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The map label for this gene is gpmB [H]

Identifier: 52143354

GI number: 52143354

Start: 2002586

End: 2003176

Strand: Direct

Name: gpmB [H]

Synonym: BCZK1881

Alternate gene names: 52143354

Gene position: 2002586-2003176 (Clockwise)

Preceding gene: 52143356

Following gene: 52143355

Centisome position: 37.78

GC content: 36.55

Gene sequence:

>591_bases
ATGCAAATACTACTAATACGCCACGGAGAATCAGAAGCTGATATTTTAAACGTACATGAAGGACGAGCTGACTTTGAATT
AACAGAAAAGGGAAGAGAGCAGGTGCAAAGACTTGTAAAGAAAGTGAAAGCAGATTTTCCACCAGATTTCATTTGGGCAA
GTACATTAAAACGTGCTCGTGAAACTGGTGAAACGTTAGCAGAGGGAATTGGATGTCCAATTCAATTAGAAGAGGAATTA
ATGGAGTTCAATAATGGAGTGCAAGCAGGTCTTTCATTTGAAGAAGCTCAGAAATATCCCGAGCCAAAGTTTCTTCATGA
TCGTTTTGAAAACGGGGAATCATTTATTGAATTTAGAATGAGAATAGAAGGCATCTTTTCTAAAATCGTGACGGAGAATA
CATATGACCGAATTGCAATTGTTGCACACGGTGGTGTAATAAATAGTCTATTACGTGCGTTTTTCAAAATGCCAATTTCA
ATGGACTATTATTTTAAAATGGGAGATACGGGAATAAGCTTACTTGAAATGGATGGCGAACAAAAAACGGTACATTTTAT
TAATGATACAAATCATTTGGACGGGATGTAA

Upstream 100 bases:

>100_bases
GAAAAAGAGAAATGGGATGCCATTTCTCTTTTTTGTTATAGAAAATTCAGAGTATGATATAATGGAATTTTTCGGATATT
AAAAAGGGGAGTGGAGAAAC

Downstream 100 bases:

>100_bases
AGACCTATGTACAAGATAGTGTTTTTTGATGTTGATGGAACGCTTTTAAGTGAGATTGATAGAAGTATGCACGAAAGTAC
AAAGGAAGCGATACAAAGAT

Product: phosphoglycerate mutase

Products: NA

Alternate protein names: PGAM; Phosphoglyceromutase [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MQILLIRHGESEADILNVHEGRADFELTEKGREQVQRLVKKVKADFPPDFIWASTLKRARETGETLAEGIGCPIQLEEEL
MEFNNGVQAGLSFEEAQKYPEPKFLHDRFENGESFIEFRMRIEGIFSKIVTENTYDRIAIVAHGGVINSLLRAFFKMPIS
MDYYFKMGDTGISLLEMDGEQKTVHFINDTNHLDGM

Sequences:

>Translated_196_residues
MQILLIRHGESEADILNVHEGRADFELTEKGREQVQRLVKKVKADFPPDFIWASTLKRARETGETLAEGIGCPIQLEEEL
MEFNNGVQAGLSFEEAQKYPEPKFLHDRFENGESFIEFRMRIEGIFSKIVTENTYDRIAIVAHGGVINSLLRAFFKMPIS
MDYYFKMGDTGISLLEMDGEQKTVHFINDTNHLDGM
>Mature_196_residues
MQILLIRHGESEADILNVHEGRADFELTEKGREQVQRLVKKVKADFPPDFIWASTLKRARETGETLAEGIGCPIQLEEEL
MEFNNGVQAGLSFEEAQKYPEPKFLHDRFENGESFIEFRMRIEGIFSKIVTENTYDRIAIVAHGGVINSLLRAFFKMPIS
MDYYFKMGDTGISLLEMDGEQKTVHFINDTNHLDGM

Specific function: Converts N1-(5-Phospho-Alpha-D-Ribosyl)-5,6- Dimethylbenzimidazole Into N1-Alpha-D-Ribosyl-5,6- Dimethylbenzimidazole; Involved In The Assembly Of The Nucleotide Loop Of Cobalamin. [C]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. GpmB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786857, Length=196, Percent_Identity=28.0612244897959, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI1790856, Length=207, Percent_Identity=24.6376811594203, Blast_Score=68, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6324857, Length=203, Percent_Identity=26.1083743842365, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR023086 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 22464; Mature: 22464

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQILLIRHGESEADILNVHEGRADFELTEKGREQVQRLVKKVKADFPPDFIWASTLKRAR
CEEEEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ETGETLAEGIGCPIQLEEELMEFNNGVQAGLSFEEAQKYPEPKFLHDRFENGESFIEFRM
HHHHHHHHHCCCCEEHHHHHHHHCCCHHCCCCHHHHHCCCCCCHHHHHHHCCHHHHHHHH
RIEGIFSKIVTENTYDRIAIVAHGGVINSLLRAFFKMPISMDYYFKMGDTGISLLEMDGE
HHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEECCC
QKTVHFINDTNHLDGM
CCEEEEECCCCCCCCC
>Mature Secondary Structure
MQILLIRHGESEADILNVHEGRADFELTEKGREQVQRLVKKVKADFPPDFIWASTLKRAR
CEEEEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ETGETLAEGIGCPIQLEEELMEFNNGVQAGLSFEEAQKYPEPKFLHDRFENGESFIEFRM
HHHHHHHHHCCCCEEHHHHHHHHCCCHHCCCCHHHHHCCCCCCHHHHHHHCCHHHHHHHH
RIEGIFSKIVTENTYDRIAIVAHGGVINSLLRAFFKMPISMDYYFKMGDTGISLLEMDGE
HHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEECCC
QKTVHFINDTNHLDGM
CCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA