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The map label for this gene is yokL [H]

Identifier: 52143343

GI number: 52143343

Start: 2015076

End: 2015642

Strand: Direct

Name: yokL [H]

Synonym: BCZK1895

Alternate gene names: 52143343

Gene position: 2015076-2015642 (Clockwise)

Preceding gene: 52143344

Following gene: 52143339

Centisome position: 38.01

GC content: 38.62

Gene sequence:

>567_bases
ATGAAAAGCGTAATCATAAAAGGGGATAAAGTAACAATTCGTACAATTGAAGAATCAGATATAAAAACATTATGGAATCT
CGTGTTTAAAGAAGAAAATCCAGAATGGAAAAAATGGGATGCACCGTATTTTCCGTTTTCGATGCAAGAATACTCAGCCT
ATAAGGAAAAGATGCAAACTCGTTTAAAAGAAGAACCGCTATCCAATTTAATTATAGAAAATAACGGTCAAGTTATAGGG
ACGGTCGGATTTTATTGGGAGTATAAACCGACGCGTTGGTTGGAGATGGGAATTGTCATTTATAATCCGGCTTACTGGAA
TGGCGGCTACGGTACAGAAGCGTTAACGTTATATCGGGATTTACTATTTGAAAAGATGGAGATTGGTAGAGTAGGGCTCA
CGACTTGGTCTGGTAATGAACGAATGATGAAAGTGGCGGAGAAAATAGGAATGAGCCTAGAAGGTAGAATGCGAAAATGC
CGTTATTATAACGGAACGTACTATGACTCTATTCGAATGGGAATGATTCGTGAAGAATGGGAAGCGCTATGTGTAACAAA
GGGGTGA

Upstream 100 bases:

>100_bases
TATAACAAAATTATACAATATAATAAACGATATCTGTTTTGATTTTTCAGAAAAAACATTATAATTATATATGAAATAAA
GAGGAGTGTAGGAGGAAATT

Downstream 100 bases:

>100_bases
AGGGATATGTACGCTATTATTGCTACATTTGATCGTGTATTTACTAATAAAATTACAGAATTGCAAAATGAATTAACAAA
TATCATTGGCACAAATCAAT

Product: acetyltransferase

Products: Coenzyme A; H+; N8-Acetylspermidine [C]

Alternate protein names: NA

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MKSVIIKGDKVTIRTIEESDIKTLWNLVFKEENPEWKKWDAPYFPFSMQEYSAYKEKMQTRLKEEPLSNLIIENNGQVIG
TVGFYWEYKPTRWLEMGIVIYNPAYWNGGYGTEALTLYRDLLFEKMEIGRVGLTTWSGNERMMKVAEKIGMSLEGRMRKC
RYYNGTYYDSIRMGMIREEWEALCVTKG

Sequences:

>Translated_188_residues
MKSVIIKGDKVTIRTIEESDIKTLWNLVFKEENPEWKKWDAPYFPFSMQEYSAYKEKMQTRLKEEPLSNLIIENNGQVIG
TVGFYWEYKPTRWLEMGIVIYNPAYWNGGYGTEALTLYRDLLFEKMEIGRVGLTTWSGNERMMKVAEKIGMSLEGRMRKC
RYYNGTYYDSIRMGMIREEWEALCVTKG
>Mature_188_residues
MKSVIIKGDKVTIRTIEESDIKTLWNLVFKEENPEWKKWDAPYFPFSMQEYSAYKEKMQTRLKEEPLSNLIIENNGQVIG
TVGFYWEYKPTRWLEMGIVIYNPAYWNGGYGTEALTLYRDLLFEKMEIGRVGLTTWSGNERMMKVAEKIGMSLEGRMRKC
RYYNGTYYDSIRMGMIREEWEALCVTKG

Specific function: Regulates Polyamine Concentration By Their Degradation. Acts On Spermidine, Forming N(1)- And N(8)-Acetylspermidine. [C]

COG id: COG1670

COG function: function code J; Acetyltransferases, including N-acetylases of ribosomal proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181 [H]

Pfam domain/function: PF00583 Acetyltransf_1 [H]

EC number: 2.3.1.57 [C]

Molecular weight: Translated: 22261; Mature: 22261

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSVIIKGDKVTIRTIEESDIKTLWNLVFKEENPEWKKWDAPYFPFSMQEYSAYKEKMQT
CCCEEEECCEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
RLKEEPLSNLIIENNGQVIGTVGFYWEYKPTRWLEMGIVIYNPAYWNGGYGTEALTLYRD
HHHHCCHHCEEEECCCCEEEEEEEEEECCCCEEEEEEEEEECCCEECCCCCHHHHHHHHH
LLFEKMEIGRVGLTTWSGNERMMKVAEKIGMSLEGRMRKCRYYNGTYYDSIRMGMIREEW
HHHHHHHCCEEEEEEECCCHHHHHHHHHHCCCCCCHHHEEEECCCEEECHHHHHHHHHHH
EALCVTKG
HEEEEECC
>Mature Secondary Structure
MKSVIIKGDKVTIRTIEESDIKTLWNLVFKEENPEWKKWDAPYFPFSMQEYSAYKEKMQT
CCCEEEECCEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
RLKEEPLSNLIIENNGQVIGTVGFYWEYKPTRWLEMGIVIYNPAYWNGGYGTEALTLYRD
HHHHCCHHCEEEECCCCEEEEEEEEEECCCCEEEEEEEEEECCCEECCCCCHHHHHHHHH
LLFEKMEIGRVGLTTWSGNERMMKVAEKIGMSLEGRMRKCRYYNGTYYDSIRMGMIREEW
HHHHHHHCCEEEEEEECCCHHHHHHHHHHCCCCCCHHHEEEECCCEEECHHHHHHHHHHH
EALCVTKG
HEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; Spermidine [C]

Specific reaction: Acetyl-CoA + Spermidine --> Coenzyme A + H+ + N8-Acetylspermidine [C]

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]