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The map label for this gene is ileS [H]

Identifier: 52143260

GI number: 52143260

Start: 2092834

End: 2095935

Strand: Direct

Name: ileS [H]

Synonym: BCZK1977

Alternate gene names: 52143260

Gene position: 2092834-2095935 (Clockwise)

Preceding gene: 52143261

Following gene: 52143259

Centisome position: 39.48

GC content: 37.3

Gene sequence:

>3102_bases
ATGAAGAAAGTAGATGTAAAAGAGTCAGCTGTAGGGAGAGAAACACGTATTCGTAAACAGTGGAACGAGCAAAGCATTTT
CGAGCAATCAATTCAGAATCGAGAAGGCGCACAATCTTTTGTTTTTTATGAAGGACCACCGACGGCGAATGGATTACCAC
ATGTAGGTCATGCACTTGGACGAACAATTAAAGATGTAGTAGCAAGATATAAAACGATGGCTGGTTATAAAGTGTTAAGA
AAAGCGGGATGGGATACGCACGGCTTACCTGTAGAATTAGGTGTTGAGAAGCAACTCGGTATTTCTGGTAAACATGAAAT
CGAGGAGTACGGAATTGAACCATTTATTAAGAAGTGTAAAGAGAGTGTATTCACATATGAGAAGCAGTGGCGTGAATTCA
CTGAAAGCATCGGTTATTGGGTCGATATGGATGATCCATACGTTACGTTAGAGAATCCATATATCGAAAGTGTATGGCAT
ATTTTAGGGACGATTCATGAAAAAGGGTTATTGTATAAAGGGCATAGAGTTTCACCATATTGCCCAAGCTGTCAAACTTC
ACTAAGTTCACATGAGGTTGCCCAAGGGTATAAAACAGTAAAAGATTTAAGTGCAACAGTTAAGTTTAAAGTGAAAGATA
GTGAAAATGAATATTTCCTAGGTTGGACGACAACACCTTGGACACTTCCAGCGAATGTTGCACTCGCTGTACATCCAAAT
ATGGAATACGTGAAAGCAAAACAAGAAGGTCATGTATACATTGTTGCGAAAGAACGTGTACAAGATGTATTAAAAGAAAA
CTATGAAGTATTATCTGTTCATAAGGGAGAAGAATTATTAAATATTTCTTATACAGCACCGTTTCCAATGAAAGAAGTTA
CAAATGGTTACCGCGTTATCGGAGCAGATTTCGTAACGGCAGATAGTGGTACAGGACTTGTTCATATTGCTCCAGCATAC
GGAGAGGACGATTATAGAGTCGTGCAAAGTGAAGGATTGTCATTTTTGCATGTTGTAGATGAAAAGGGTGAGTATACAGA
AGCCGTACCATTTTTGAAAGGTAAATTTGTAAAAGATTGTGACGTAGATATCGTTCGTTATTTAGCGAAGGAAGGTTTAC
TGTATCATAAAGAAAAGTATGAACATAGTTACCCGCATTGCTGGCGCTGTGATTCACCACTTCTTTATTATGCAGGAGAG
AGCTGGTTAATCCGAACGACTGCAATTAAGGATACATTTTTACAAAATAATGATTCTGTTACTTGGTATCCAGATCATAT
GAAACATGGACGCTTTGGTAAGTTTTTAGAAAATATGGTGGACTGGAATATTAGCCGAAATAGATATTGGGGAACACCAT
TAAACGTATGGGAATGTGAAAGTTGCGATCATCAATTTGCACCGAAAAGCATTGATGATTTAAGAAAGCATAGTACGAAA
GAAACACAGGAAGATTTAGAATTGCATAAGCCCTATGTAGATGAAGTGCAAGTTTGCTGCGAAAAATGCGGTGGCACAAT
GACTCGTACACCAGAAGTAATTGATGTTTGGTTTGATAGTGGTTCCATGCCATTTGCGCAATATCATTATCCATTTGAAA
ATAAAGAGTTATTTGAAGAACAGTTTCCAGCAGATGTAATTGCAGAAGGAATTGATCAAACACGTGGCTGGTTTTATAGT
TTATTAGCAGTATCAGCACTATATACAGGAAAAGTGCCTTATAAACGAGTGTTATCACTAGGGCATGTATTAGACGAAGA
AGGACAGAAAATGTCTAAAAGTAAAGGGAATGCACTAGATCCAGTTGATTTAGTAAATCAGTTTGGTGCAGATGCTTTAA
GATGGGCTCTACTTGTTGATAGTGCTCCGTGGAATGCGAAACGTTTTTCTGAAAGAACAGTACTGGAAGCGAAATCTAAA
TTTGTAGATACGTTAGTCAATGTGTATAGCTTCTACGTTTTATATGCAAATTTAGATGAGTATAATCCGAATGAAACATA
TGACGTAAAGCGGACGAAATTGGATGAATGGGTATTATCAAGATTGCATAGCACAACGAAAAAAGTGAGAATAGCACTTG
ATGATTATCAATTTACGAATGCAGCTCGTGAAATTGCGGCACTTGTAGATGAAGTAAGTAACTGGTACGTAAGACGATCA
CGTAATCGTTTCTGGGAATCTGGTATGAATGCTGAAAAAGCAGCTGCGTATGAAACACTTCATGACGTGCTTGTGACAAT
TAGTAAATTAATCGCACCGTTTACACCGTTTGTCGCTGAAGATATTCATTTGAATTTAACTGGAAGTAGCGTTCATCTAG
AGGATTATCCAGTTGTAAATGAATCATTACTCCAGCCTAAATTAGAAGCGGAAATGAATGCTGTTTTACAAGTTGTTGAA
CTTGGAAGAAGTAACCGTAATCAGCATTCTTTAAAAGTAAAACAGCCGTTAGCGGAACTTGTACTACTTGAGCATAATGA
AAATGATATGGATTGGGAATCTTACCGTGATATCGTTATGGATGAGTTAAATGTGAAGGCGTTCCATGTTGAACTCGATG
AAACGAAATACACATCTTATCAATTAAAGCTGAATTTTAAAACGGCTGGGCCGAAGTTCGGTAAAAATGTGAATGCAGTA
AATGGCTGGCTAAAACAATTATCACAAGACGAGGTACAAAACTTTGTCTCTACAGAAAGAGCAGTTTACGAAGTAGCATC
AGGAGAAGAAATAGTTGTAACGACTGAAGATGTATTAGTAGAGAAAGTTGCGAAATCTGGATTCTCTAATACAACTAACG
GACAATATACAGTAATGTTAGATACGAATGTAACGGAAGAATTGCTACAAGAAGGGGTAGCACGTGAATTCATTCGCGCC
GTTCAAGAATATCGTAAGCAGTTGAATTTACCTGTTAATTTACGAGTAGATGTAATTCTTGATACAGAGGAAGAACTACA
GCAAACGTTAACGAATCATAAAGAGTTGTTGGAAGAAAACTTACTCGTTAAACAATTTACATTTGGTCACTTAACGAATG
AAGATGATGAACTATCTTTAGGTGAGACGAAAGTTCGTATTAAATTAAGCGCGACTAAGTAA

Upstream 100 bases:

>100_bases
GAGCTAATAGAATTAGGGTGGTAACGCGGTTAAACCCGTCCCTACTTCGTAGGGACGGGTTTTTTGTGTGCTTTAAAACA
TTCAAAAGGAGTGATTGTAG

Downstream 100 bases:

>100_bases
AGAAAAGGAAGTTGGAATCATTCCAACTTCCTTTTTTGTATGATAGATATTTATCCGGCTAATTTTTTCATAATCGATTC
GATAGGACCTCAAGAAAATT

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase 2; IleRS 2 [H]

Number of amino acids: Translated: 1033; Mature: 1033

Protein sequence:

>1033_residues
MKKVDVKESAVGRETRIRKQWNEQSIFEQSIQNREGAQSFVFYEGPPTANGLPHVGHALGRTIKDVVARYKTMAGYKVLR
KAGWDTHGLPVELGVEKQLGISGKHEIEEYGIEPFIKKCKESVFTYEKQWREFTESIGYWVDMDDPYVTLENPYIESVWH
ILGTIHEKGLLYKGHRVSPYCPSCQTSLSSHEVAQGYKTVKDLSATVKFKVKDSENEYFLGWTTTPWTLPANVALAVHPN
MEYVKAKQEGHVYIVAKERVQDVLKENYEVLSVHKGEELLNISYTAPFPMKEVTNGYRVIGADFVTADSGTGLVHIAPAY
GEDDYRVVQSEGLSFLHVVDEKGEYTEAVPFLKGKFVKDCDVDIVRYLAKEGLLYHKEKYEHSYPHCWRCDSPLLYYAGE
SWLIRTTAIKDTFLQNNDSVTWYPDHMKHGRFGKFLENMVDWNISRNRYWGTPLNVWECESCDHQFAPKSIDDLRKHSTK
ETQEDLELHKPYVDEVQVCCEKCGGTMTRTPEVIDVWFDSGSMPFAQYHYPFENKELFEEQFPADVIAEGIDQTRGWFYS
LLAVSALYTGKVPYKRVLSLGHVLDEEGQKMSKSKGNALDPVDLVNQFGADALRWALLVDSAPWNAKRFSERTVLEAKSK
FVDTLVNVYSFYVLYANLDEYNPNETYDVKRTKLDEWVLSRLHSTTKKVRIALDDYQFTNAAREIAALVDEVSNWYVRRS
RNRFWESGMNAEKAAAYETLHDVLVTISKLIAPFTPFVAEDIHLNLTGSSVHLEDYPVVNESLLQPKLEAEMNAVLQVVE
LGRSNRNQHSLKVKQPLAELVLLEHNENDMDWESYRDIVMDELNVKAFHVELDETKYTSYQLKLNFKTAGPKFGKNVNAV
NGWLKQLSQDEVQNFVSTERAVYEVASGEEIVVTTEDVLVEKVAKSGFSNTTNGQYTVMLDTNVTEELLQEGVAREFIRA
VQEYRKQLNLPVNLRVDVILDTEEELQQTLTNHKELLEENLLVKQFTFGHLTNEDDELSLGETKVRIKLSATK

Sequences:

>Translated_1033_residues
MKKVDVKESAVGRETRIRKQWNEQSIFEQSIQNREGAQSFVFYEGPPTANGLPHVGHALGRTIKDVVARYKTMAGYKVLR
KAGWDTHGLPVELGVEKQLGISGKHEIEEYGIEPFIKKCKESVFTYEKQWREFTESIGYWVDMDDPYVTLENPYIESVWH
ILGTIHEKGLLYKGHRVSPYCPSCQTSLSSHEVAQGYKTVKDLSATVKFKVKDSENEYFLGWTTTPWTLPANVALAVHPN
MEYVKAKQEGHVYIVAKERVQDVLKENYEVLSVHKGEELLNISYTAPFPMKEVTNGYRVIGADFVTADSGTGLVHIAPAY
GEDDYRVVQSEGLSFLHVVDEKGEYTEAVPFLKGKFVKDCDVDIVRYLAKEGLLYHKEKYEHSYPHCWRCDSPLLYYAGE
SWLIRTTAIKDTFLQNNDSVTWYPDHMKHGRFGKFLENMVDWNISRNRYWGTPLNVWECESCDHQFAPKSIDDLRKHSTK
ETQEDLELHKPYVDEVQVCCEKCGGTMTRTPEVIDVWFDSGSMPFAQYHYPFENKELFEEQFPADVIAEGIDQTRGWFYS
LLAVSALYTGKVPYKRVLSLGHVLDEEGQKMSKSKGNALDPVDLVNQFGADALRWALLVDSAPWNAKRFSERTVLEAKSK
FVDTLVNVYSFYVLYANLDEYNPNETYDVKRTKLDEWVLSRLHSTTKKVRIALDDYQFTNAAREIAALVDEVSNWYVRRS
RNRFWESGMNAEKAAAYETLHDVLVTISKLIAPFTPFVAEDIHLNLTGSSVHLEDYPVVNESLLQPKLEAEMNAVLQVVE
LGRSNRNQHSLKVKQPLAELVLLEHNENDMDWESYRDIVMDELNVKAFHVELDETKYTSYQLKLNFKTAGPKFGKNVNAV
NGWLKQLSQDEVQNFVSTERAVYEVASGEEIVVTTEDVLVEKVAKSGFSNTTNGQYTVMLDTNVTEELLQEGVAREFIRA
VQEYRKQLNLPVNLRVDVILDTEEELQQTLTNHKELLEENLLVKQFTFGHLTNEDDELSLGETKVRIKLSATK
>Mature_1033_residues
MKKVDVKESAVGRETRIRKQWNEQSIFEQSIQNREGAQSFVFYEGPPTANGLPHVGHALGRTIKDVVARYKTMAGYKVLR
KAGWDTHGLPVELGVEKQLGISGKHEIEEYGIEPFIKKCKESVFTYEKQWREFTESIGYWVDMDDPYVTLENPYIESVWH
ILGTIHEKGLLYKGHRVSPYCPSCQTSLSSHEVAQGYKTVKDLSATVKFKVKDSENEYFLGWTTTPWTLPANVALAVHPN
MEYVKAKQEGHVYIVAKERVQDVLKENYEVLSVHKGEELLNISYTAPFPMKEVTNGYRVIGADFVTADSGTGLVHIAPAY
GEDDYRVVQSEGLSFLHVVDEKGEYTEAVPFLKGKFVKDCDVDIVRYLAKEGLLYHKEKYEHSYPHCWRCDSPLLYYAGE
SWLIRTTAIKDTFLQNNDSVTWYPDHMKHGRFGKFLENMVDWNISRNRYWGTPLNVWECESCDHQFAPKSIDDLRKHSTK
ETQEDLELHKPYVDEVQVCCEKCGGTMTRTPEVIDVWFDSGSMPFAQYHYPFENKELFEEQFPADVIAEGIDQTRGWFYS
LLAVSALYTGKVPYKRVLSLGHVLDEEGQKMSKSKGNALDPVDLVNQFGADALRWALLVDSAPWNAKRFSERTVLEAKSK
FVDTLVNVYSFYVLYANLDEYNPNETYDVKRTKLDEWVLSRLHSTTKKVRIALDDYQFTNAAREIAALVDEVSNWYVRRS
RNRFWESGMNAEKAAAYETLHDVLVTISKLIAPFTPFVAEDIHLNLTGSSVHLEDYPVVNESLLQPKLEAEMNAVLQVVE
LGRSNRNQHSLKVKQPLAELVLLEHNENDMDWESYRDIVMDELNVKAFHVELDETKYTSYQLKLNFKTAGPKFGKNVNAV
NGWLKQLSQDEVQNFVSTERAVYEVASGEEIVVTTEDVLVEKVAKSGFSNTTNGQYTVMLDTNVTEELLQEGVAREFIRA
VQEYRKQLNLPVNLRVDVILDTEEELQQTLTNHKELLEENLLVKQFTFGHLTNEDDELSLGETKVRIKLSATK

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI94721239, Length=1034, Percent_Identity=35.9767891682785, Blast_Score=636, Evalue=0.0,
Organism=Homo sapiens, GI94721241, Length=1034, Percent_Identity=35.9767891682785, Blast_Score=636, Evalue=0.0,
Organism=Homo sapiens, GI46852147, Length=780, Percent_Identity=29.8717948717949, Blast_Score=285, Evalue=1e-76,
Organism=Homo sapiens, GI268370293, Length=885, Percent_Identity=22.8248587570621, Blast_Score=161, Evalue=4e-39,
Organism=Homo sapiens, GI268370297, Length=885, Percent_Identity=22.8248587570621, Blast_Score=160, Evalue=6e-39,
Organism=Homo sapiens, GI268370295, Length=857, Percent_Identity=22.9871645274212, Blast_Score=159, Evalue=1e-38,
Organism=Homo sapiens, GI5454158, Length=892, Percent_Identity=23.542600896861, Blast_Score=153, Evalue=1e-36,
Organism=Escherichia coli, GI2367096, Length=786, Percent_Identity=29.3893129770992, Blast_Score=348, Evalue=1e-96,
Organism=Escherichia coli, GI1790708, Length=894, Percent_Identity=23.1543624161074, Blast_Score=189, Evalue=7e-49,
Organism=Escherichia coli, GI1786861, Length=376, Percent_Identity=21.8085106382979, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17541896, Length=988, Percent_Identity=38.3603238866397, Blast_Score=672, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71980946, Length=788, Percent_Identity=28.1725888324873, Blast_Score=261, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI17510661, Length=869, Percent_Identity=24.1657077100115, Blast_Score=188, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI72001587, Length=878, Percent_Identity=23.5763097949886, Blast_Score=180, Evalue=4e-45,
Organism=Saccharomyces cerevisiae, GI6319395, Length=997, Percent_Identity=35.3059177532598, Blast_Score=631, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6325217, Length=782, Percent_Identity=25.9590792838875, Blast_Score=245, Evalue=3e-65,
Organism=Saccharomyces cerevisiae, GI6321531, Length=841, Percent_Identity=24.256837098692, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI28574730, Length=1052, Percent_Identity=36.1216730038023, Blast_Score=645, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668547, Length=1052, Percent_Identity=36.1216730038023, Blast_Score=645, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668543, Length=1052, Percent_Identity=36.1216730038023, Blast_Score=645, Evalue=0.0,
Organism=Drosophila melanogaster, GI281366294, Length=787, Percent_Identity=28.7166454891995, Blast_Score=263, Evalue=3e-70,
Organism=Drosophila melanogaster, GI17864482, Length=863, Percent_Identity=23.0590961761298, Blast_Score=182, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24653289, Length=863, Percent_Identity=23.0590961761298, Blast_Score=182, Evalue=1e-45,
Organism=Drosophila melanogaster, GI21355675, Length=937, Percent_Identity=22.1985058697972, Blast_Score=140, Evalue=5e-33,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008 [H]

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1 [H]

EC number: =6.1.1.5 [H]

Molecular weight: Translated: 118487; Mature: 118487

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVDVKESAVGRETRIRKQWNEQSIFEQSIQNREGAQSFVFYEGPPTANGLPHVGHALG
CCCCCCCHHHCCHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHH
RTIKDVVARYKTMAGYKVLRKAGWDTHGLPVELGVEKQLGISGKHEIEEYGIEPFIKKCK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHCCCCCCHHHHHCCCCHHHHHHH
ESVFTYEKQWREFTESIGYWVDMDDPYVTLENPYIESVWHILGTIHEKGLLYKGHRVSPY
HHHHHHHHHHHHHHHHCCEEEECCCCEEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCC
CPSCQTSLSSHEVAQGYKTVKDLSATVKFKVKDSENEYFLGWTTTPWTLPANVALAVHPN
CCCHHHCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCEEEEECCCCCCCCCCEEEEECCC
MEYVKAKQEGHVYIVAKERVQDVLKENYEVLSVHKGEELLNISYTAPFPMKEVTNGYRVI
HHHHHCCCCCCEEEEEHHHHHHHHHCCCEEEEEECCCEEEEEEECCCCCHHHHCCCEEEE
GADFVTADSGTGLVHIAPAYGEDDYRVVQSEGLSFLHVVDEKGEYTEAVPFLKGKFVKDC
EEEEEEECCCCCEEEEECCCCCCCCEEHHHCCCEEEEEECCCCCHHHHCHHHCCCCCCCC
DVDIVRYLAKEGLLYHKEKYEHSYPHCWRCDSPLLYYAGESWLIRTTAIKDTFLQNNDSV
CHHHHHHHHHCCCEEEHHHHCCCCCCCCCCCCCEEEEECCCEEEEEEHHHHHHHCCCCCE
TWYPDHMKHGRFGKFLENMVDWNISRNRYWGTPLNVWECESCDHQFAPKSIDDLRKHSTK
EECCCHHCCCCHHHHHHHHHCCCCCCCEECCCCCCCEECCCCCCCCCCCCHHHHHHCCCH
ETQEDLELHKPYVDEVQVCCEKCGGTMTRTPEVIDVWFDSGSMPFAQYHYPFENKELFEE
HHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHEECCCCCCHHHHHH
QFPADVIAEGIDQTRGWFYSLLAVSALYTGKVPYKRVLSLGHVLDEEGQKMSKSKGNALD
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
PVDLVNQFGADALRWALLVDSAPWNAKRFSERTVLEAKSKFVDTLVNVYSFYVLYANLDE
HHHHHHHHCHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
YNPNETYDVKRTKLDEWVLSRLHSTTKKVRIALDDYQFTNAAREIAALVDEVSNWYVRRS
CCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
RNRFWESGMNAEKAAAYETLHDVLVTISKLIAPFTPFVAEDIHLNLTGSSVHLEDYPVVN
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCEEEEEECCEEEECCCCCCC
ESLLQPKLEAEMNAVLQVVELGRSNRNQHSLKVKQPLAELVLLEHNENDMDWESYRDIVM
HHHHCCHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHEEEECCCCCCCHHHHHHHHH
DELNVKAFHVELDETKYTSYQLKLNFKTAGPKFGKNVNAVNGWLKQLSQDEVQNFVSTER
HCCCEEEEEEEECCCEEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AVYEVASGEEIVVTTEDVLVEKVAKSGFSNTTNGQYTVMLDTNVTEELLQEGVAREFIRA
HHHEECCCCEEEEEHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHH
VQEYRKQLNLPVNLRVDVILDTEEELQQTLTNHKELLEENLLVKQFTFGHLTNEDDELSL
HHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCC
GETKVRIKLSATK
CCEEEEEEEECCC
>Mature Secondary Structure
MKKVDVKESAVGRETRIRKQWNEQSIFEQSIQNREGAQSFVFYEGPPTANGLPHVGHALG
CCCCCCCHHHCCHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHH
RTIKDVVARYKTMAGYKVLRKAGWDTHGLPVELGVEKQLGISGKHEIEEYGIEPFIKKCK
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHCCCCCCHHHHHCCCCHHHHHHH
ESVFTYEKQWREFTESIGYWVDMDDPYVTLENPYIESVWHILGTIHEKGLLYKGHRVSPY
HHHHHHHHHHHHHHHHCCEEEECCCCEEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCC
CPSCQTSLSSHEVAQGYKTVKDLSATVKFKVKDSENEYFLGWTTTPWTLPANVALAVHPN
CCCHHHCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCEEEEECCCCCCCCCCEEEEECCC
MEYVKAKQEGHVYIVAKERVQDVLKENYEVLSVHKGEELLNISYTAPFPMKEVTNGYRVI
HHHHHCCCCCCEEEEEHHHHHHHHHCCCEEEEEECCCEEEEEEECCCCCHHHHCCCEEEE
GADFVTADSGTGLVHIAPAYGEDDYRVVQSEGLSFLHVVDEKGEYTEAVPFLKGKFVKDC
EEEEEEECCCCCEEEEECCCCCCCCEEHHHCCCEEEEEECCCCCHHHHCHHHCCCCCCCC
DVDIVRYLAKEGLLYHKEKYEHSYPHCWRCDSPLLYYAGESWLIRTTAIKDTFLQNNDSV
CHHHHHHHHHCCCEEEHHHHCCCCCCCCCCCCCEEEEECCCEEEEEEHHHHHHHCCCCCE
TWYPDHMKHGRFGKFLENMVDWNISRNRYWGTPLNVWECESCDHQFAPKSIDDLRKHSTK
EECCCHHCCCCHHHHHHHHHCCCCCCCEECCCCCCCEECCCCCCCCCCCCHHHHHHCCCH
ETQEDLELHKPYVDEVQVCCEKCGGTMTRTPEVIDVWFDSGSMPFAQYHYPFENKELFEE
HHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHEECCCCCCHHHHHH
QFPADVIAEGIDQTRGWFYSLLAVSALYTGKVPYKRVLSLGHVLDEEGQKMSKSKGNALD
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
PVDLVNQFGADALRWALLVDSAPWNAKRFSERTVLEAKSKFVDTLVNVYSFYVLYANLDE
HHHHHHHHCHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
YNPNETYDVKRTKLDEWVLSRLHSTTKKVRIALDDYQFTNAAREIAALVDEVSNWYVRRS
CCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
RNRFWESGMNAEKAAAYETLHDVLVTISKLIAPFTPFVAEDIHLNLTGSSVHLEDYPVVN
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCEEEEEECCEEEECCCCCCC
ESLLQPKLEAEMNAVLQVVELGRSNRNQHSLKVKQPLAELVLLEHNENDMDWESYRDIVM
HHHHCCHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHEEEECCCCCCCHHHHHHHHH
DELNVKAFHVELDETKYTSYQLKLNFKTAGPKFGKNVNAVNGWLKQLSQDEVQNFVSTER
HCCCEEEEEEEECCCEEEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AVYEVASGEEIVVTTEDVLVEKVAKSGFSNTTNGQYTVMLDTNVTEELLQEGVAREFIRA
HHHEECCCCEEEEEHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHH
VQEYRKQLNLPVNLRVDVILDTEEELQQTLTNHKELLEENLLVKQFTFGHLTNEDDELSL
HHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCC
GETKVRIKLSATK
CCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]