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The map label for this gene is cisA [H]

Identifier: 52143243

GI number: 52143243

Start: 2117396

End: 2118181

Strand: Direct

Name: cisA [H]

Synonym: BCZK1994

Alternate gene names: 52143243

Gene position: 2117396-2118181 (Clockwise)

Preceding gene: 52143244

Following gene: 52143242

Centisome position: 39.94

GC content: 37.66

Gene sequence:

>786_bases
ATGGGAGAGAAAGTAGTTGGTTATGTACGAGTTTCAACGGAAGGACAAGTGCGTGAAGGGTATAGCCTAACGTATCAAGT
AGAAGAAATTGAACGGTACTGCATCGAAAATAAACTACAACTGCTTCACATATACGAAGATAAAGGAATCAGCGGAGCGA
CAGTAGATGAAGATGGATTAACAGTTGAACGTGAAGGATTACAAGAGCTATTGTCAGATTTGGCGTATCAACAAGTGAGC
CACGTGATTGTACTAAATACATCTCGGTTATGGCGCTCTGATATGGCAAAAGTGTTAATACAACGAGAACTAAAGAAACA
TGAGGTTGATGTAAAAGCAATTGAACAACCAAATTATAGTATATACACGCATGACCCAAATGACTTTTTAGTAAATGGTA
TGTTAGAGCTATTAGATCAATATCAACGTCTTGAGATTGCATTAAAGCTAAGTAGAGGCAGAAAGAAAAAAGCAGAACAA
GGTGGATATGCGGGGGGCGGTGTGATGTTTGGTTATAGAGTAAAGAAAGGACAAAAAGTGTTAGAGGTAGATGCGGAGAA
AGCGATAGTTGTACGTAGACTATTTGAATTAAGACACTTTTTTAAACATTGGTCGCTAACTCAATTGGCAGAACGACTAA
ATAGGGAAGGGTATTGTACTGAGAAAAGAAAGTTGTTTACGAAAGTGCAAGTGAAACGTATGTTAGACCGAGAGAACTTT
TATCGAGGGGTATATACATACGGGCAAATACAAACAATTGGGAAACATCCAGTAATTATTTTATAA

Upstream 100 bases:

>100_bases
TAAAGTACGTTTTAACGGATGGACGTTATGCACACGTTATCCGCAAAAAACAGGTAAACGTTACAGGGACTTTAATTGCT
GTAACGGGAAGGGGCTCAAT

Downstream 100 bases:

>100_bases
ACTCACTTAAAAAATTAGCTCATTTTACTATACATACTACTAGAGTTATGAAAAATGGATAGGCTTGCGTACCTATGCGC
ATCGGAAGATGAACGCTCGA

Product: resolvase

Products: NA

Alternate protein names: Stage IV sporulation protein CA [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MGEKVVGYVRVSTEGQVREGYSLTYQVEEIERYCIENKLQLLHIYEDKGISGATVDEDGLTVEREGLQELLSDLAYQQVS
HVIVLNTSRLWRSDMAKVLIQRELKKHEVDVKAIEQPNYSIYTHDPNDFLVNGMLELLDQYQRLEIALKLSRGRKKKAEQ
GGYAGGGVMFGYRVKKGQKVLEVDAEKAIVVRRLFELRHFFKHWSLTQLAERLNREGYCTEKRKLFTKVQVKRMLDRENF
YRGVYTYGQIQTIGKHPVIIL

Sequences:

>Translated_261_residues
MGEKVVGYVRVSTEGQVREGYSLTYQVEEIERYCIENKLQLLHIYEDKGISGATVDEDGLTVEREGLQELLSDLAYQQVS
HVIVLNTSRLWRSDMAKVLIQRELKKHEVDVKAIEQPNYSIYTHDPNDFLVNGMLELLDQYQRLEIALKLSRGRKKKAEQ
GGYAGGGVMFGYRVKKGQKVLEVDAEKAIVVRRLFELRHFFKHWSLTQLAERLNREGYCTEKRKLFTKVQVKRMLDRENF
YRGVYTYGQIQTIGKHPVIIL
>Mature_260_residues
GEKVVGYVRVSTEGQVREGYSLTYQVEEIERYCIENKLQLLHIYEDKGISGATVDEDGLTVEREGLQELLSDLAYQQVSH
VIVLNTSRLWRSDMAKVLIQRELKKHEVDVKAIEQPNYSIYTHDPNDFLVNGMLELLDQYQRLEIALKLSRGRKKKAEQG
GYAGGGVMFGYRVKKGQKVLEVDAEKAIVVRRLFELRHFFKHWSLTQLAERLNREGYCTEKRKLFTKVQVKRMLDRENFY
RGVYTYGQIQTIGKHPVIIL

Specific function: Putative site-specific recombinase having a very important role in sporulation. It probably plays a role in the recombination of spoIIIC and spoIVCB to form sigma K factor [H]

COG id: COG1961

COG function: function code L; Site-specific recombinases, DNA invertase Pin homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 recombinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011109
- InterPro:   IPR006118
- InterPro:   IPR006119 [H]

Pfam domain/function: PF07508 Recombinase; PF00239 Resolvase [H]

EC number: NA

Molecular weight: Translated: 30376; Mature: 30245

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS00397 RECOMBINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEKVVGYVRVSTEGQVREGYSLTYQVEEIERYCIENKLQLLHIYEDKGISGATVDEDGL
CCCCEEEEEEECCCCCCCCCCEEEEEHHHHHHHHHHCCEEEEEEEECCCCCCCEECCCCC
TVEREGLQELLSDLAYQQVSHVIVLNTSRLWRSDMAKVLIQRELKKHEVDVKAIEQPNYS
EEEHHHHHHHHHHHHHHHHCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCE
IYTHDPNDFLVNGMLELLDQYQRLEIALKLSRGRKKKAEQGGYAGGGVMFGYRVKKGQKV
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCEEEEEEECCCCEE
LEVDAEKAIVVRRLFELRHFFKHWSLTQLAERLNREGYCTEKRKLFTKVQVKRMLDRENF
EECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
YRGVYTYGQIQTIGKHPVIIL
HHHHEEECEEEECCCCCEEEC
>Mature Secondary Structure 
GEKVVGYVRVSTEGQVREGYSLTYQVEEIERYCIENKLQLLHIYEDKGISGATVDEDGL
CCCEEEEEEECCCCCCCCCCEEEEEHHHHHHHHHHCCEEEEEEEECCCCCCCEECCCCC
TVEREGLQELLSDLAYQQVSHVIVLNTSRLWRSDMAKVLIQRELKKHEVDVKAIEQPNYS
EEEHHHHHHHHHHHHHHHHCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCE
IYTHDPNDFLVNGMLELLDQYQRLEIALKLSRGRKKKAEQGGYAGGGVMFGYRVKKGQKV
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCEEEEEEECCCCEE
LEVDAEKAIVVRRLFELRHFFKHWSLTQLAERLNREGYCTEKRKLFTKVQVKRMLDRENF
EECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
YRGVYTYGQIQTIGKHPVIIL
HHHHEEECEEEECCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2105293; 7704261; 8969508; 9384377 [H]