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The map label for this gene is sfp [H]

Identifier: 52143104

GI number: 52143104

Start: 2263646

End: 2264395

Strand: Direct

Name: sfp [H]

Synonym: BCZK2134

Alternate gene names: 52143104

Gene position: 2263646-2264395 (Clockwise)

Preceding gene: 52143106

Following gene: 52143103

Centisome position: 42.7

GC content: 36.27

Gene sequence:

>750_bases
ATGATAGAAAGTAAAGTTGTAGATTCTATACCAACTTTGAATGAGAATGATTGTCAAATATGGTGGGGAAGAATTTCAGA
TTTACAATCATGGCATTATAATTTACTAAATGATGTTGAACGAGAGAAAGCAAATTCATATCATCATTCGGCAGATCGTG
CCCGTTTTATAATCGGTTGCGTAATTAGTAGATTAGTTCTTGGAAAGATACTTTCTATGTCGCCAGTTCAAGTTCCGATT
GATCGAATGTGCCCAGTATGTAAGTTACAACATGGTAGACCACAATTACCAGAAGGCATGCCGCAGTTATCCGTTTCACA
TTCGGGTGAGTGGGTTGTTGTTGCATTTACAAAGTTTGCACCTGTAGGCGTTGATGTTGAACAAATGAATCCGAATGTGG
ATGTTATGAAAATGGCGGATGGCGTATTAACAGACAGTGAAAAAGCGCAAGTTATGAAATTACCTAATGAACAGAAAATA
GAAGGTTTTTTAACATATTGGACTAGAAAAGAAGCAGTGCTAAAAGCGACTGGTGAAGGACTAATGATTTCACCAGTGGA
TATTACTATATCAGCTCCAAATGATTCTCCAAACTTATTGGTTTTTAAGGATAGACAAGAGTTAGTAGAAAATACAGTGA
TGAGAGATTTAAGGCCAAGTGTAGATTATATGGCTTCTATTGCAATATGTAGTAAAGAAGTCACCGAAATTACACAGTTG
GACGCAGTAGCGCTTTTAACTTATAAATAA

Upstream 100 bases:

>100_bases
AATGTCAAAGAAGAAAGAAAAAATGTTATCCGTAACAAAAAAAGAGAAAGCACTTGTCAATGAATAACAATTGATATTCG
TTATATAAAGGAGAGTTTTC

Downstream 100 bases:

>100_bases
GTTAAATAAAATATTTTATAGAAGAGGTGTTCCTCATGTTAGTAGCGGAAAATAGAACAAATGAATTCACATATAATGTA
CAAGCAATCAAAAATATTTT

Product: 4'-phosphopantetheinyl transferase

Products: adenosine 3',5'-bisphosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MIESKVVDSIPTLNENDCQIWWGRISDLQSWHYNLLNDVEREKANSYHHSADRARFIIGCVISRLVLGKILSMSPVQVPI
DRMCPVCKLQHGRPQLPEGMPQLSVSHSGEWVVVAFTKFAPVGVDVEQMNPNVDVMKMADGVLTDSEKAQVMKLPNEQKI
EGFLTYWTRKEAVLKATGEGLMISPVDITISAPNDSPNLLVFKDRQELVENTVMRDLRPSVDYMASIAICSKEVTEITQL
DAVALLTYK

Sequences:

>Translated_249_residues
MIESKVVDSIPTLNENDCQIWWGRISDLQSWHYNLLNDVEREKANSYHHSADRARFIIGCVISRLVLGKILSMSPVQVPI
DRMCPVCKLQHGRPQLPEGMPQLSVSHSGEWVVVAFTKFAPVGVDVEQMNPNVDVMKMADGVLTDSEKAQVMKLPNEQKI
EGFLTYWTRKEAVLKATGEGLMISPVDITISAPNDSPNLLVFKDRQELVENTVMRDLRPSVDYMASIAICSKEVTEITQL
DAVALLTYK
>Mature_249_residues
MIESKVVDSIPTLNENDCQIWWGRISDLQSWHYNLLNDVEREKANSYHHSADRARFIIGCVISRLVLGKILSMSPVQVPI
DRMCPVCKLQHGRPQLPEGMPQLSVSHSGEWVVVAFTKFAPVGVDVEQMNPNVDVMKMADGVLTDSEKAQVMKLPNEQKI
EGFLTYWTRKEAVLKATGEGLMISPVDITISAPNDSPNLLVFKDRQELVENTVMRDLRPSVDYMASIAICSKEVTEITQL
DAVALLTYK

Specific function: Probably activates the acyl carrier protein (ACP) domain of hetM, by transferring the 4'-phosphopantetheinyl moiety of coenzyme A (CoA) to a serine residue. May be required for maintaining vegetative growth and probably acts via hetN to inhibit differenti

COG id: COG2091

COG function: function code H; Phosphopantetheinyl transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. Gsp/sfp/hetI/acpT family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: NA

Molecular weight: Translated: 27956; Mature: 27956

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIESKVVDSIPTLNENDCQIWWGRISDLQSWHYNLLNDVEREKANSYHHSADRARFIIGC
CCCCHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VISRLVLGKILSMSPVQVPIDRMCPVCKLQHGRPQLPEGMPQLSVSHSGEWVVVAFTKFA
HHHHHHHHHHHCCCCCCCCHHHCCCHHCCCCCCCCCCCCCCCEEECCCCCEEEEEEECCC
PVGVDVEQMNPNVDVMKMADGVLTDSEKAQVMKLPNEQKIEGFLTYWTRKEAVLKATGEG
CCCCCHHHCCCCCEEEECCCCCCCCCCCHHEEECCCHHHHHHHHHHHHHHHHHEEECCCC
LMISPVDITISAPNDSPNLLVFKDRQELVENTVMRDLRPSVDYMASIAICSKEVTEITQL
EEEECEEEEEECCCCCCCEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
DAVALLTYK
CEEEEEEEC
>Mature Secondary Structure
MIESKVVDSIPTLNENDCQIWWGRISDLQSWHYNLLNDVEREKANSYHHSADRARFIIGC
CCCCHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VISRLVLGKILSMSPVQVPIDRMCPVCKLQHGRPQLPEGMPQLSVSHSGEWVVVAFTKFA
HHHHHHHHHHHCCCCCCCCHHHCCCHHCCCCCCCCCCCCCCCEEECCCCCEEEEEEECCC
PVGVDVEQMNPNVDVMKMADGVLTDSEKAQVMKLPNEQKIEGFLTYWTRKEAVLKATGEG
CCCCCHHHCCCCCEEEECCCCCCCCCCCHHEEECCCHHHHHHHHHHHHHHHHHEEECCCC
LMISPVDITISAPNDSPNLLVFKDRQELVENTVMRDLRPSVDYMASIAICSKEVTEITQL
EEEECEEEEEECCCCCCCEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
DAVALLTYK
CEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coenzyme A; apo-[acyl carrier protein] [C]

Specific reaction: Coenzyme A + apo-[acyl carrier protein] = adenosine 3',5'-bisphosphate + [acyl carrier protein] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8157596; 11759840; 8939709 [H]