Click here to switch to the map view.

The map label for this gene is mdmC [H]

Identifier: 52143030

GI number: 52143030

Start: 2335576

End: 2336169

Strand: Direct

Name: mdmC [H]

Synonym: BCZK2207

Alternate gene names: 52143030

Gene position: 2335576-2336169 (Clockwise)

Preceding gene: 52143032

Following gene: 52143031

Centisome position: 44.06

GC content: 33.84

Gene sequence:

>594_bases
ATGAAAAAAATGGATACATTAAATTCATTATTATTTCAACTTGAACAATATGGAGAAGAGCATGATCGAAATAAAAAAAC
ACGGGAAGAAAAATTACGGAATATTTCGCGTGAGATGGGGCAATTTTTATCAATTTTAGTAAAAGGGTGTAGTGTAAAAA
ACATTTTAGAAATTGGAACTTCTAATGGTTATTCTACATTGTGGTTAGCTGATGCGGTAGAAGAAACAAATGGAAATGTA
ACAACTGTAGAGCTTTCCTCAGAACGAGTTGGAGAGGCACTTGCCAATTTTGAAAAGGCAAACCTTTTACAAAGGATTGA
TGTTCACAATCAAGAAGCAGGGGCATTTTTAGATTCACAACTAGATCATTCATTTGATTTTATTTTCCTAGATTCAGAGC
GTACGCAATACATGTGGTGGCTTGAGCATATAAAACGCATTTTACAACCAAAAGGTCTTCTTGTTGTCGATAATGCTACT
TCTCATGCGAGTGAATTAGCTGAGTTTATAAAAATGATTGAAGAAGATAAAATGTTTGAAACAGTGTTATTGGCATTTCA
AAATGGTGCATTTGTAGCGCGTAAGAAGCAATAG

Upstream 100 bases:

>100_bases
ATAAATCTTTGTCATATAACGAGAAAAAGGTTTTTGTTTCGCATATAATGAAAGTAGACGAGCAACAAGAGCTTTTTCAT
CATATTGCTTTAGAAAGGCG

Downstream 100 bases:

>100_bases
GATTGAACGCAATATAATTATCACATTGAAAAAGGGTGTATGTCAAAAGATTGAGTACAGTAGGATGGGAAGGACGTAAT
TTATATATGTAACATACGAA

Product: caffeoyl-CoA O-methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MKKMDTLNSLLFQLEQYGEEHDRNKKTREEKLRNISREMGQFLSILVKGCSVKNILEIGTSNGYSTLWLADAVEETNGNV
TTVELSSERVGEALANFEKANLLQRIDVHNQEAGAFLDSQLDHSFDFIFLDSERTQYMWWLEHIKRILQPKGLLVVDNAT
SHASELAEFIKMIEEDKMFETVLLAFQNGAFVARKKQ

Sequences:

>Translated_197_residues
MKKMDTLNSLLFQLEQYGEEHDRNKKTREEKLRNISREMGQFLSILVKGCSVKNILEIGTSNGYSTLWLADAVEETNGNV
TTVELSSERVGEALANFEKANLLQRIDVHNQEAGAFLDSQLDHSFDFIFLDSERTQYMWWLEHIKRILQPKGLLVVDNAT
SHASELAEFIKMIEEDKMFETVLLAFQNGAFVARKKQ
>Mature_197_residues
MKKMDTLNSLLFQLEQYGEEHDRNKKTREEKLRNISREMGQFLSILVKGCSVKNILEIGTSNGYSTLWLADAVEETNGNV
TTVELSSERVGEALANFEKANLLQRIDVHNQEAGAFLDSQLDHSFDFIFLDSERTQYMWWLEHIKRILQPKGLLVVDNAT
SHASELAEFIKMIEEDKMFETVLLAFQNGAFVARKKQ

Specific function: 4-O-methyltransferase for the lactone ring of midecamycin and other macrolide antibiotics [H]

COG id: COG4122

COG function: function code R; Predicted O-methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. Type 3 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002935 [H]

Pfam domain/function: PF01596 Methyltransf_3 [H]

EC number: NA

Molecular weight: Translated: 22647; Mature: 22647

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKMDTLNSLLFQLEQYGEEHDRNKKTREEKLRNISREMGQFLSILVKGCSVKNILEIGT
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
SNGYSTLWLADAVEETNGNVTTVELSSERVGEALANFEKANLLQRIDVHNQEAGAFLDSQ
CCCCEEEHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LDHSFDFIFLDSERTQYMWWLEHIKRILQPKGLLVVDNATSHASELAEFIKMIEEDKMFE
CCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHH
TVLLAFQNGAFVARKKQ
HHHHHHCCCCEEEECCC
>Mature Secondary Structure
MKKMDTLNSLLFQLEQYGEEHDRNKKTREEKLRNISREMGQFLSILVKGCSVKNILEIGT
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
SNGYSTLWLADAVEETNGNVTTVELSSERVGEALANFEKANLLQRIDVHNQEAGAFLDSQ
CCCCEEEHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
LDHSFDFIFLDSERTQYMWWLEHIKRILQPKGLLVVDNATSHASELAEFIKMIEEDKMFE
CCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHH
TVLLAFQNGAFVARKKQ
HHHHHHCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1629172 [H]