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The map label for this gene is kinB [H]

Identifier: 52142853

GI number: 52142853

Start: 2524025

End: 2525293

Strand: Reverse

Name: kinB [H]

Synonym: BCZK2387

Alternate gene names: 52142853

Gene position: 2525293-2524025 (Counterclockwise)

Preceding gene: 52142852

Following gene: 52142858

Centisome position: 47.64

GC content: 28.05

Gene sequence:

>1269_bases
ATGAACTTTGTGTATATCAATCAACACGTATTAAATAACCTTCTATATATTTTAAGTAGTATATTTATTTTTTATTTTTT
ATATGATAGCGGACGCAATTTGAAGAAATATAAAAAACTACTTATTATACTTTGTACGAGTATCCCTCTTATTCTATGTA
TGCGCTATCCTATCTATATGGATGAAAGTTGTATTCATGATTTAAGACAAATACCAGTTATAATAGGTACGCTTTATGGT
GGCTTCCCTGTCGGTATCATATTGCTTGCTATTTTATTAATTACAAGATTTTTATTTTATGGATTTAGCATGTTAACAAT
AGTAGTTTATGGAACAATGTTTATCATTACAGCATTCGCATCCGCAAAATTTAATACGTATAATAGAAAAATTAAAGTAG
CTTATGCAATGTTTTTAACATTTTTTCTAGCAATATTTACAACTGTAATTGTATTAACTTTATCAGATTTTGAAGTGAAT
AATTTGTATATTATTTATTTTATAATATTACCAACTATTTTAATGTTGTTTGTAGTTTATTTTAATGAAGTTTTAAAAGA
TGCATTATGTATGCGATCGAAGTTAATTAAAATGGAAAAAATGGAGATTGTTAGCCAACTCGCTGCTAGTATATCGCACG
AAGTAAGAAATCCCTTAACTGTCGTAAAAGGATTTACTCAACTTTTAAAAACACCAAATTTAACTCCAGAATCAAGAGAT
GAGTATATTAAGCATATACTAGAAGAATTACATCGTGCTCAAGAAATTATTGATGATTATTTAACGTTTGCCAAACCTGC
TTCAGAAAAATTAGATGAGATTTCAGTAGAACAAGAGTTAAATCGAGTTATTAATATGATCTTACCTTTATGTAATATGA
ATACAATACATATTACAAAAGATTTCTCTACGGCAACAATAGTTGGTAATAAACAACACTTTCAGCAATGTTTTTTAAAT
TTAATAAAAAATGGTATTGAAGCAATGCCTAATGGCGGTACTTTAAATATCTCCTCATCTATTAGTAATAATAAGGTTAT
CATACGTATTGAAGATAGCGGAATTGGTATGTCACAAGAGCAAATAAATCGATTTGGCGAACCGTATTTTAGTACAAAAA
CGAAAGGTACAGGTTTAGGTACAATGGTTGCTGTGAAAATCATTGAAACGATGCAAGGTAGTTTGAAAATCCGAAGCGTT
ATTAATAAAGGAACTACTTTGACAATTACATTCCCGAAATGTAATAAAAACTCATCTAACAACAAATAA

Upstream 100 bases:

>100_bases
AATAAAATATAAATCTATATTATTCAAACAAACATATAGTTTATACTATTATCATGTTAATATATATGAAAAGGAAATTA
AAAATAACGAGGCAAATATT

Downstream 100 bases:

>100_bases
AAAAGGAGCATAATCGCTCCTTTTTTATTTGTTTCGATACAGAAGTATCTTCTATGTTTTTTTAGTTTACATTTGTGGAG
ACTAATTAGAAATTAGTACC

Product: sporulation kinase B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MNFVYINQHVLNNLLYILSSIFIFYFLYDSGRNLKKYKKLLIILCTSIPLILCMRYPIYMDESCIHDLRQIPVIIGTLYG
GFPVGIILLAILLITRFLFYGFSMLTIVVYGTMFIITAFASAKFNTYNRKIKVAYAMFLTFFLAIFTTVIVLTLSDFEVN
NLYIIYFIILPTILMLFVVYFNEVLKDALCMRSKLIKMEKMEIVSQLAASISHEVRNPLTVVKGFTQLLKTPNLTPESRD
EYIKHILEELHRAQEIIDDYLTFAKPASEKLDEISVEQELNRVINMILPLCNMNTIHITKDFSTATIVGNKQHFQQCFLN
LIKNGIEAMPNGGTLNISSSISNNKVIIRIEDSGIGMSQEQINRFGEPYFSTKTKGTGLGTMVAVKIIETMQGSLKIRSV
INKGTTLTITFPKCNKNSSNNK

Sequences:

>Translated_422_residues
MNFVYINQHVLNNLLYILSSIFIFYFLYDSGRNLKKYKKLLIILCTSIPLILCMRYPIYMDESCIHDLRQIPVIIGTLYG
GFPVGIILLAILLITRFLFYGFSMLTIVVYGTMFIITAFASAKFNTYNRKIKVAYAMFLTFFLAIFTTVIVLTLSDFEVN
NLYIIYFIILPTILMLFVVYFNEVLKDALCMRSKLIKMEKMEIVSQLAASISHEVRNPLTVVKGFTQLLKTPNLTPESRD
EYIKHILEELHRAQEIIDDYLTFAKPASEKLDEISVEQELNRVINMILPLCNMNTIHITKDFSTATIVGNKQHFQQCFLN
LIKNGIEAMPNGGTLNISSSISNNKVIIRIEDSGIGMSQEQINRFGEPYFSTKTKGTGLGTMVAVKIIETMQGSLKIRSV
INKGTTLTITFPKCNKNSSNNK
>Mature_422_residues
MNFVYINQHVLNNLLYILSSIFIFYFLYDSGRNLKKYKKLLIILCTSIPLILCMRYPIYMDESCIHDLRQIPVIIGTLYG
GFPVGIILLAILLITRFLFYGFSMLTIVVYGTMFIITAFASAKFNTYNRKIKVAYAMFLTFFLAIFTTVIVLTLSDFEVN
NLYIIYFIILPTILMLFVVYFNEVLKDALCMRSKLIKMEKMEIVSQLAASISHEVRNPLTVVKGFTQLLKTPNLTPESRD
EYIKHILEELHRAQEIIDDYLTFAKPASEKLDEISVEQELNRVINMILPLCNMNTIHITKDFSTATIVGNKQHFQQCFLN
LIKNGIEAMPNGGTLNISSSISNNKVIIRIEDSGIGMSQEQINRFGEPYFSTKTKGTGLGTMVAVKIIETMQGSLKIRSV
INKGTTLTITFPKCNKNSSNNK

Specific function: Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. Spo0F is required for the kinB activity [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=278, Percent_Identity=26.2589928057554, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1788549, Length=228, Percent_Identity=27.6315789473684, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1789149, Length=232, Percent_Identity=30.1724137931034, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI145693157, Length=246, Percent_Identity=27.6422764227642, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1786600, Length=258, Percent_Identity=23.2558139534884, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788713, Length=232, Percent_Identity=27.5862068965517, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790300, Length=226, Percent_Identity=24.7787610619469, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790861, Length=232, Percent_Identity=22.4137931034483, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788393, Length=242, Percent_Identity=22.7272727272727, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1786783, Length=229, Percent_Identity=21.3973799126638, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48086; Mature: 48086

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFVYINQHVLNNLLYILSSIFIFYFLYDSGRNLKKYKKLLIILCTSIPLILCMRYPIYM
CCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
DESCIHDLRQIPVIIGTLYGGFPVGIILLAILLITRFLFYGFSMLTIVVYGTMFIITAFA
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAKFNTYNRKIKVAYAMFLTFFLAIFTTVIVLTLSDFEVNNLYIIYFIILPTILMLFVVY
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHH
FNEVLKDALCMRSKLIKMEKMEIVSQLAASISHEVRNPLTVVKGFTQLLKTPNLTPESRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCHH
EYIKHILEELHRAQEIIDDYLTFAKPASEKLDEISVEQELNRVINMILPLCNMNTIHITK
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
DFSTATIVGNKQHFQQCFLNLIKNGIEAMPNGGTLNISSSISNNKVIIRIEDSGIGMSQE
CCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEECCCCCCCHH
QINRFGEPYFSTKTKGTGLGTMVAVKIIETMQGSLKIRSVINKGTTLTITFPKCNKNSSN
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCC
NK
CC
>Mature Secondary Structure
MNFVYINQHVLNNLLYILSSIFIFYFLYDSGRNLKKYKKLLIILCTSIPLILCMRYPIYM
CCEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
DESCIHDLRQIPVIIGTLYGGFPVGIILLAILLITRFLFYGFSMLTIVVYGTMFIITAFA
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAKFNTYNRKIKVAYAMFLTFFLAIFTTVIVLTLSDFEVNNLYIIYFIILPTILMLFVVY
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHH
FNEVLKDALCMRSKLIKMEKMEIVSQLAASISHEVRNPLTVVKGFTQLLKTPNLTPESRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCHH
EYIKHILEELHRAQEIIDDYLTFAKPASEKLDEISVEQELNRVINMILPLCNMNTIHITK
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
DFSTATIVGNKQHFQQCFLNLIKNGIEAMPNGGTLNISSSISNNKVIIRIEDSGIGMSQE
CCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEECCCCCCCHH
QINRFGEPYFSTKTKGTGLGTMVAVKIIETMQGSLKIRSVINKGTTLTITFPKCNKNSSN
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCC
NK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8497199; 9274030; 9384377 [H]