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The map label for this gene is gntR [H]

Identifier: 52142822

GI number: 52142822

Start: 2557755

End: 2559191

Strand: Reverse

Name: gntR [H]

Synonym: BCZK2419

Alternate gene names: 52142822

Gene position: 2559191-2557755 (Counterclockwise)

Preceding gene: 52142807

Following gene: 52142823

Centisome position: 48.28

GC content: 34.1

Gene sequence:

>1437_bases
TTGATGACAACTAGTAAAAAAACAACTAAGTATCGGCAAATAGTAGACTATATGAAAGAAAAAATTGAAAATGGAGAATG
GCCAATTGGAAGTAAGATTCCTAGTCAAAGGCAATTAGCGAAATTATTTCAAGTAAATCGTAGCACTGTAATAACTGCAC
TAGATGAACTTATGGCTGATGGATTGATTCAAGGGAAAATTGGAGCAGGAACAATTGTAACGAATAATACATGGTCATTA
TTAGCGACGAATCCACCACCTGATTGGAGTGAATATGTAAAGGCCGGTATTCATAAACCAAGCAAGTTAATGGTACGAGA
AATAAATGAAGCAGAAGCAAATAACAAACTTATCCATCTAAGTAAAGGTGAACTTGCTCCTCATCTTTTTCCGTTAGAGA
CGATGCAGTCCATTATGAAAAAAGTAAGTGAGGAATTAGATTATTTTGGATATGAGGAACAAAAAGGGTTTTATCCGTTA
CGTGAAGCAATAAGTAAATATGTAAAATCATTTGGAATACAGGCATCACCAAGTTCCATATTAATCGTCTCGGGTGCATT
ACAAGCATTGCAATTAATATCAATTGGTCTTTTACATAGAGAGTCAACCGTCTTACTTGAACAACCTTCTTACTTATATT
CACTTCATGTATTTCAATCAGCAAATATAAATCTATCTGGTATATCTATGGATCCTCACGGTATATTACCTAACGAGTTA
TTAAAACGAATTAAATACAGTCAGAAGAAAAACATTTTATATTCAATTCCTTGTTTTCAAAATCCAACAGGCATATTAAT
GTCTAAAGAGCGGAGAAAAGAAATATTAAAAATATGTGAAAAGGAACAGTTACCTATTATTGAAGATGATATTTACCGCG
AGTTATGGATTGATGCACCGCCCCCAGCTCCTTTAAAATCAAGGGATAAACATGGACATGTATTATATATTGGTAGTCTC
TCTAAGACACTTACCCCAGGACTTAGAATTGGATGGATTATCGGTCCAGAACCGGTTATTGATAGATTATCAGATATAAA
AATGCAAACAGATTATGGATCAAGCTCCTTATCCCAAAGAGTTGCTGCTGAATGGATAAATAAAGGGTTTTATGAGGAAC
ATGTAGCGAACGTAAGAATTAAACTAAAAGAACGAAGACAAATAATGATACGAGCTTTAAATAAGTATTGCGCAGATATT
GCATCGTGGGATATCCCTACTGGTGGATTTTTTATATGGCTAAAGGTAGTACCTAGCATTCCGATGAAGAAATTATTTTC
AGAGGCACTATCAAAAGGAATTCTTTTAAACCCAGGACGTATCTATGAAGAAGAAACAGATCGATACATTCGTTTATCAT
ATGGATATGCTTCTCCAGAGCAAATGACTAACGGGATTAAATTGTTGAGTGAATTAATTCGTAAGTTAATGACATAA

Upstream 100 bases:

>100_bases
TTTCTTTTCATCATATTTAATAGTTGATACAATGTCTTCAACCAGTTTTTTATCGTAAAAACCAACCACTTGGCATTTTT
CAAGTGAACGAAGGAGTTTT

Downstream 100 bases:

>100_bases
CAAAAACTCCTCTTTTTCTATAGAGGAGTTTTTGTGTATTTTATTTACCACAATCTCATTTCCTGCCCTAATAAAATAAG
TGCTTCATAAGGATCCCCGT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MMTTSKKTTKYRQIVDYMKEKIENGEWPIGSKIPSQRQLAKLFQVNRSTVITALDELMADGLIQGKIGAGTIVTNNTWSL
LATNPPPDWSEYVKAGIHKPSKLMVREINEAEANNKLIHLSKGELAPHLFPLETMQSIMKKVSEELDYFGYEEQKGFYPL
REAISKYVKSFGIQASPSSILIVSGALQALQLISIGLLHRESTVLLEQPSYLYSLHVFQSANINLSGISMDPHGILPNEL
LKRIKYSQKKNILYSIPCFQNPTGILMSKERRKEILKICEKEQLPIIEDDIYRELWIDAPPPAPLKSRDKHGHVLYIGSL
SKTLTPGLRIGWIIGPEPVIDRLSDIKMQTDYGSSSLSQRVAAEWINKGFYEEHVANVRIKLKERRQIMIRALNKYCADI
ASWDIPTGGFFIWLKVVPSIPMKKLFSEALSKGILLNPGRIYEEETDRYIRLSYGYASPEQMTNGIKLLSELIRKLMT

Sequences:

>Translated_478_residues
MMTTSKKTTKYRQIVDYMKEKIENGEWPIGSKIPSQRQLAKLFQVNRSTVITALDELMADGLIQGKIGAGTIVTNNTWSL
LATNPPPDWSEYVKAGIHKPSKLMVREINEAEANNKLIHLSKGELAPHLFPLETMQSIMKKVSEELDYFGYEEQKGFYPL
REAISKYVKSFGIQASPSSILIVSGALQALQLISIGLLHRESTVLLEQPSYLYSLHVFQSANINLSGISMDPHGILPNEL
LKRIKYSQKKNILYSIPCFQNPTGILMSKERRKEILKICEKEQLPIIEDDIYRELWIDAPPPAPLKSRDKHGHVLYIGSL
SKTLTPGLRIGWIIGPEPVIDRLSDIKMQTDYGSSSLSQRVAAEWINKGFYEEHVANVRIKLKERRQIMIRALNKYCADI
ASWDIPTGGFFIWLKVVPSIPMKKLFSEALSKGILLNPGRIYEEETDRYIRLSYGYASPEQMTNGIKLLSELIRKLMT
>Mature_478_residues
MMTTSKKTTKYRQIVDYMKEKIENGEWPIGSKIPSQRQLAKLFQVNRSTVITALDELMADGLIQGKIGAGTIVTNNTWSL
LATNPPPDWSEYVKAGIHKPSKLMVREINEAEANNKLIHLSKGELAPHLFPLETMQSIMKKVSEELDYFGYEEQKGFYPL
REAISKYVKSFGIQASPSSILIVSGALQALQLISIGLLHRESTVLLEQPSYLYSLHVFQSANINLSGISMDPHGILPNEL
LKRIKYSQKKNILYSIPCFQNPTGILMSKERRKEILKICEKEQLPIIEDDIYRELWIDAPPPAPLKSRDKHGHVLYIGSL
SKTLTPGLRIGWIIGPEPVIDRLSDIKMQTDYGSSSLSQRVAAEWINKGFYEEHVANVRIKLKERRQIMIRALNKYCADI
ASWDIPTGGFFIWLKVVPSIPMKKLFSEALSKGILLNPGRIYEEETDRYIRLSYGYASPEQMTNGIKLLSELIRKLMT

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=314, Percent_Identity=31.2101910828025, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI33469970, Length=314, Percent_Identity=31.2101910828025, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI4507369, Length=258, Percent_Identity=27.1317829457364, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI1787710, Length=471, Percent_Identity=24.416135881104, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1790797, Length=484, Percent_Identity=26.2396694214876, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1788722, Length=329, Percent_Identity=23.7082066869301, Blast_Score=81, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6321236, Length=361, Percent_Identity=24.6537396121884, Blast_Score=97, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6321000, Length=271, Percent_Identity=26.1992619926199, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356535, Length=355, Percent_Identity=24.2253521126761, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI18859735, Length=205, Percent_Identity=26.3414634146341, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 54295; Mature: 54295

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTTSKKTTKYRQIVDYMKEKIENGEWPIGSKIPSQRQLAKLFQVNRSTVITALDELMAD
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHC
GLIQGKIGAGTIVTNNTWSLLATNPPPDWSEYVKAGIHKPSKLMVREINEAEANNKLIHL
CCEECCCCCCEEEECCCEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEE
SKGELAPHLFPLETMQSIMKKVSEELDYFGYEEQKGFYPLREAISKYVKSFGIQASPSSI
ECCCCCCCEECHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHCCCCCCCCCE
LIVSGALQALQLISIGLLHRESTVLLEQPSYLYSLHVFQSANINLSGISMDPHGILPNEL
EEEHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEEECCEEEEEECCCCCCCCHHHH
LKRIKYSQKKNILYSIPCFQNPTGILMSKERRKEILKICEKEQLPIIEDDIYRELWIDAP
HHHHHHHHHCCEEEECCCCCCCCCCEECHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCC
PPAPLKSRDKHGHVLYIGSLSKTLTPGLRIGWIIGPEPVIDRLSDIKMQTDYGSSSLSQR
CCCCCCCCCCCCCEEEEECCHHHCCCCCEEEEEECCHHHHHHHHHCEEECCCCCHHHHHH
VAAEWINKGFYEEHVANVRIKLKERRQIMIRALNKYCADIASWDIPTGGFFIWLKVVPSI
HHHHHHHCCHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHCCC
PMKKLFSEALSKGILLNPGRIYEEETDRYIRLSYGYASPEQMTNGIKLLSELIRKLMT
CHHHHHHHHHHCCEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMTTSKKTTKYRQIVDYMKEKIENGEWPIGSKIPSQRQLAKLFQVNRSTVITALDELMAD
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHC
GLIQGKIGAGTIVTNNTWSLLATNPPPDWSEYVKAGIHKPSKLMVREINEAEANNKLIHL
CCEECCCCCCEEEECCCEEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEE
SKGELAPHLFPLETMQSIMKKVSEELDYFGYEEQKGFYPLREAISKYVKSFGIQASPSSI
ECCCCCCCEECHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHCCCCCCCCCE
LIVSGALQALQLISIGLLHRESTVLLEQPSYLYSLHVFQSANINLSGISMDPHGILPNEL
EEEHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEEECCEEEEEECCCCCCCCHHHH
LKRIKYSQKKNILYSIPCFQNPTGILMSKERRKEILKICEKEQLPIIEDDIYRELWIDAP
HHHHHHHHHCCEEEECCCCCCCCCCEECHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCC
PPAPLKSRDKHGHVLYIGSLSKTLTPGLRIGWIIGPEPVIDRLSDIKMQTDYGSSSLSQR
CCCCCCCCCCCCCEEEEECCHHHCCCCCEEEEEECCHHHHHHHHHCEEECCCCCHHHHHH
VAAEWINKGFYEEHVANVRIKLKERRQIMIRALNKYCADIASWDIPTGGFFIWLKVVPSI
HHHHHHHCCHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHCCC
PMKKLFSEALSKGILLNPGRIYEEETDRYIRLSYGYASPEQMTNGIKLLSELIRKLMT
CHHHHHHHHHHCCEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]