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The map label for this gene is nudH [C]

Identifier: 52142750

GI number: 52142750

Start: 2623880

End: 2624317

Strand: Reverse

Name: nudH [C]

Synonym: BCZK2490

Alternate gene names: 52142750

Gene position: 2624317-2623880 (Counterclockwise)

Preceding gene: 52142745

Following gene: 52142752

Centisome position: 49.51

GC content: 36.99

Gene sequence:

>438_bases
ATGTCGATGCCCCTATATTATAAAAAAATCCGTGAGCAATTAGGTCATGAACTAATTTTTATACCGAGTGTAGCTGCTAT
TATTAAAAATGAGCAAGGGAAAATCTTATTTCAATATCCTGGCGGAGAATACTGGAGCTTGCCAGCTGGAGCAATTGAAC
CTGGAGAAACTCCAGAAGAAGCAGTAGTTCGGGAGGTTTGGGAAGAAACGGGGCTTAAAGTACGAGTGAAAAAGCAAAAA
GGGATATTTGGAGGGAAAGAGTTCCGGCATACATATTCGAATGGAGATCAAGTAGAATACATTGTTGTTGTGTTTGAATG
TGAAGTTATCAGTGGTAAGCTGAAGGCAATAGATGGTGAATCTTTAAAACTAAAATATTTCTCATTATCTGAAAAGCCTT
CTTTAGCGCTACCATACCCAAATAATATATTTTTATAA

Upstream 100 bases:

>100_bases
TCATTTTCTTATCCTTTCTATATAGAAATTGTTATTGGTATTATTATATAATAAGTGTCAGAAAATACAGTTATTTATTA
ATAGAGTGGGAGAGAATTAT

Downstream 100 bases:

>100_bases
ATGTAAAATAGCACACCTCATGTATTGAAGGTGTGCTATTTATATAAACCAGTCGTATACATTTTCGTCAATGTATGCAC
AATTTCTTCTAGGTCGATCT

Product: MutT/Nudix family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 144

Protein sequence:

>145_residues
MSMPLYYKKIREQLGHELIFIPSVAAIIKNEQGKILFQYPGGEYWSLPAGAIEPGETPEEAVVREVWEETGLKVRVKKQK
GIFGGKEFRHTYSNGDQVEYIVVVFECEVISGKLKAIDGESLKLKYFSLSEKPSLALPYPNNIFL

Sequences:

>Translated_145_residues
MSMPLYYKKIREQLGHELIFIPSVAAIIKNEQGKILFQYPGGEYWSLPAGAIEPGETPEEAVVREVWEETGLKVRVKKQK
GIFGGKEFRHTYSNGDQVEYIVVVFECEVISGKLKAIDGESLKLKYFSLSEKPSLALPYPNNIFL
>Mature_144_residues
SMPLYYKKIREQLGHELIFIPSVAAIIKNEQGKILFQYPGGEYWSLPAGAIEPGETPEEAVVREVWEETGLKVRVKKQKG
IFGGKEFRHTYSNGDQVEYIVVVFECEVISGKLKAIDGESLKLKYFSLSEKPSLALPYPNNIFL

Specific function: Preferentially Hydrolyzes Diadenosine Penta-Phosphate With ATP As One Of The Reaction Products. Also Able To Hydrolyze Diadenosine Hexa- And Tetra-Phosphate. Has No Activity On Diadenosine Tri-Phosphate, Adp-Ribose, NADH And Udp-Glucose. In The Meningitis

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006357
- InterPro:   IPR023215
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00702 Hydrolase; PF00293 NUDIX [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 16427; Mature: 16296

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMPLYYKKIREQLGHELIFIPSVAAIIKNEQGKILFQYPGGEYWSLPAGAIEPGETPEE
CCCCHHHHHHHHHHCCEEEEECCEEEEEECCCCCEEEECCCCCEEECCCCCCCCCCCHHH
AVVREVWEETGLKVRVKKQKGIFGGKEFRHTYSNGDQVEYIVVVFECEVISGKLKAIDGE
HHHHHHHHHCCCEEEEECCCCCCCCHHHHEECCCCCEEEEEEEEEEEEEECCEEEEECCC
SLKLKYFSLSEKPSLALPYPNNIFL
CEEEEEEECCCCCCEECCCCCCCCC
>Mature Secondary Structure 
SMPLYYKKIREQLGHELIFIPSVAAIIKNEQGKILFQYPGGEYWSLPAGAIEPGETPEE
CCCHHHHHHHHHHCCEEEEECCEEEEEECCCCCEEEECCCCCEEECCCCCCCCCCCHHH
AVVREVWEETGLKVRVKKQKGIFGGKEFRHTYSNGDQVEYIVVVFECEVISGKLKAIDGE
HHHHHHHHHCCCEEEEECCCCCCCCHHHHEECCCCCEEEEEEEEEEEEEECCEEEEECCC
SLKLKYFSLSEKPSLALPYPNNIFL
CEEEEEEECCCCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631946 [H]