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The map label for this gene is acoR [H]

Identifier: 52142748

GI number: 52142748

Start: 2626596

End: 2628446

Strand: Reverse

Name: acoR [H]

Synonym: BCZK2495

Alternate gene names: 52142748

Gene position: 2628446-2626596 (Counterclockwise)

Preceding gene: 52142744

Following gene: 52142747

Centisome position: 49.58

GC content: 34.68

Gene sequence:

>1851_bases
ATGTTAGCTTCACCGTTTTACTTACATACATGGAAAAAATTTGTTGATGAAGGAGTCCTTGATTCGAACCGTATAAACGA
AAGAATTTCAGAGTCATGGTATCGATGTAAACAAGCAAATGTGAATCCTCATATGAATAAAGGTCAGAAAATTTTGTCTT
CTAATATTTTTCAAGACCAAAAGAAAAAGAGTGAAATCTTCTTAGATATAGCAATACCTCAAATACAAAATATGAGAAAA
ACCATTGATGAACTGCAAATGATGGCATTATTAATTGATCCAGATGGTTACGTTCTATCGTTAAGTGGAAATGAACAAAC
ATTGAAACGAGCAAAACATATTAACTTCATTGAAGGTGTGAAATGGACGGAAGCAGCTGTTGGTACAAATGCAATAGGAA
CAGCGCTTGAGATTGAAGAGGCTATTATGATAAGTGGTACAGAGCATTATTCTGTCGCATCTCATAGCTGGAGCTGTGCG
GCTGCTCCCATTCATAACGATGATGGGAAATTAATTGGTGTTCTAGATTTCTCCTGTCCAATTGAATTTTCGCATCCATA
TATGCTCGGAATGGTAACTTCGATTGCACATGCGATTGAACGTGAATGTAGTATTCGAGTACATCAAAATGAACTGCATT
TAATCCATCGTTTTTTAGATGTAATTGACAGTAATGAACAAGTTGTAATTTGTAATCATCGTAATGTTATCGTTTCTGCA
AGCAAGAGGGTTCGGGAACGAGTAACTAATTGGTCACGAATGAAACTTGAAGATTTAATGCACTATGGATTGAAAACTAA
ATTAGAAGTTCCAGTATACAGTAATAATAGAATGATTGGGAAATGTATTTATGTAAAGGAAAATAAACAAGAAAAATTAT
TTTCAACTTCCCCATTTATAAATGGCATTACTTTCCCTGGAGTAATTGGGACAAGCGATGCATTTCAACATACATTAGAA
GAAATTAAGCTTGTATCACCAACTGATGCAAGTGTATATGTTTGTGGTGAAACAGGTGTAGGAAAAGAATATGTAGCGAG
AGCGATTCATGAAAATAGTCCAAGAAAAAATGGTCCTTTTATAGCTGTTAACTGCGGTGCATTACCGAAAGAATTAATGG
AAAGTGAATTGTTTGGTTATGCTGAAGGAGCGTTTACAGGTGCACGGCGTCAAGGATATAAAGGGAAATTCGAACAAGCA
GACGGAGGAACAATATTTTTAGATGAAATTGGTGAAGTGCCTCCAGAGATGCAAGTAGCATTATTACGTGTTTTACAAGA
ACGAACAGTAACCCCAATTGGCAGTTCAAAAGAGGTGCCAGTAAATATCCGTATTATCACTGCGACACATAAAGATTTAT
TGCGATTAGTAGAAGAAGGGAAATTTCGTCAAGATTTATATTATCGCTTACATGTTTATCCGCTATATGTTCCATCATTA
ATAGAAAGAAAAGAGGATATTCCGTACTTCATACAACATTTTTGTGAACGAAAGAATTGGAATATTGTATTTCCGAAGAG
TATTTGTAATCAGTTTTCACAGCATACATGGCCCGGAAATATTCGAGAATTATTAAATGTATTAGAACGTATTTACATTT
TGTCGCAAGGACGGGAAATATGCGAAAAACAAATCTCTTTTTTATTACAAACAATGATGAGAAATCAACATCAGCTTGAA
TTGCAAACAGAAAATAAAACAGAGGACACATTGAATTTCCGTGAAAAAATACAGCGTGATAGCATGATTGAAGCGCTAGA
AAAGACGAACGGAAATGTTTCGTTAGCTGCAAAACTGTTAGATGTACCTCGAAGTACATTTTATAAACGAATGCAAAAAT
ATAAGTTATAA

Upstream 100 bases:

>100_bases
GTGTCGTCTTTCTAGTTTTATTGAAAACGCTTTTATTCAGTTTTATAATAAAAGTATGTTTTTTACAGATCTCCAAAACA
ATAAATAGGGAGATGATACA

Downstream 100 bases:

>100_bases
AGTAGATTTTTGTAATCTACTTTTTCTTTGTGAGCTCATGTTCTGTCGGAATGTGCGCTTACCGGGGAAATAATAGAATA
GTTAGAAATTAATTCCCGGA

Product: sigma-54-dependent transcriptional activator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 616; Mature: 616

Protein sequence:

>616_residues
MLASPFYLHTWKKFVDEGVLDSNRINERISESWYRCKQANVNPHMNKGQKILSSNIFQDQKKKSEIFLDIAIPQIQNMRK
TIDELQMMALLIDPDGYVLSLSGNEQTLKRAKHINFIEGVKWTEAAVGTNAIGTALEIEEAIMISGTEHYSVASHSWSCA
AAPIHNDDGKLIGVLDFSCPIEFSHPYMLGMVTSIAHAIERECSIRVHQNELHLIHRFLDVIDSNEQVVICNHRNVIVSA
SKRVRERVTNWSRMKLEDLMHYGLKTKLEVPVYSNNRMIGKCIYVKENKQEKLFSTSPFINGITFPGVIGTSDAFQHTLE
EIKLVSPTDASVYVCGETGVGKEYVARAIHENSPRKNGPFIAVNCGALPKELMESELFGYAEGAFTGARRQGYKGKFEQA
DGGTIFLDEIGEVPPEMQVALLRVLQERTVTPIGSSKEVPVNIRIITATHKDLLRLVEEGKFRQDLYYRLHVYPLYVPSL
IERKEDIPYFIQHFCERKNWNIVFPKSICNQFSQHTWPGNIRELLNVLERIYILSQGREICEKQISFLLQTMMRNQHQLE
LQTENKTEDTLNFREKIQRDSMIEALEKTNGNVSLAAKLLDVPRSTFYKRMQKYKL

Sequences:

>Translated_616_residues
MLASPFYLHTWKKFVDEGVLDSNRINERISESWYRCKQANVNPHMNKGQKILSSNIFQDQKKKSEIFLDIAIPQIQNMRK
TIDELQMMALLIDPDGYVLSLSGNEQTLKRAKHINFIEGVKWTEAAVGTNAIGTALEIEEAIMISGTEHYSVASHSWSCA
AAPIHNDDGKLIGVLDFSCPIEFSHPYMLGMVTSIAHAIERECSIRVHQNELHLIHRFLDVIDSNEQVVICNHRNVIVSA
SKRVRERVTNWSRMKLEDLMHYGLKTKLEVPVYSNNRMIGKCIYVKENKQEKLFSTSPFINGITFPGVIGTSDAFQHTLE
EIKLVSPTDASVYVCGETGVGKEYVARAIHENSPRKNGPFIAVNCGALPKELMESELFGYAEGAFTGARRQGYKGKFEQA
DGGTIFLDEIGEVPPEMQVALLRVLQERTVTPIGSSKEVPVNIRIITATHKDLLRLVEEGKFRQDLYYRLHVYPLYVPSL
IERKEDIPYFIQHFCERKNWNIVFPKSICNQFSQHTWPGNIRELLNVLERIYILSQGREICEKQISFLLQTMMRNQHQLE
LQTENKTEDTLNFREKIQRDSMIEALEKTNGNVSLAAKLLDVPRSTFYKRMQKYKL
>Mature_616_residues
MLASPFYLHTWKKFVDEGVLDSNRINERISESWYRCKQANVNPHMNKGQKILSSNIFQDQKKKSEIFLDIAIPQIQNMRK
TIDELQMMALLIDPDGYVLSLSGNEQTLKRAKHINFIEGVKWTEAAVGTNAIGTALEIEEAIMISGTEHYSVASHSWSCA
AAPIHNDDGKLIGVLDFSCPIEFSHPYMLGMVTSIAHAIERECSIRVHQNELHLIHRFLDVIDSNEQVVICNHRNVIVSA
SKRVRERVTNWSRMKLEDLMHYGLKTKLEVPVYSNNRMIGKCIYVKENKQEKLFSTSPFINGITFPGVIGTSDAFQHTLE
EIKLVSPTDASVYVCGETGVGKEYVARAIHENSPRKNGPFIAVNCGALPKELMESELFGYAEGAFTGARRQGYKGKFEQA
DGGTIFLDEIGEVPPEMQVALLRVLQERTVTPIGSSKEVPVNIRIITATHKDLLRLVEEGKFRQDLYYRLHVYPLYVPSL
IERKEDIPYFIQHFCERKNWNIVFPKSICNQFSQHTWPGNIRELLNVLERIYILSQGREICEKQISFLLQTMMRNQHQLE
LQTENKTEDTLNFREKIQRDSMIEALEKTNGNVSLAAKLLDVPRSTFYKRMQKYKL

Specific function: Acts as a transcriptional activator of the acoABCL operon encoding the acetoin dehydrogenase complex [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=324, Percent_Identity=42.5925925925926, Blast_Score=265, Evalue=6e-72,
Organism=Escherichia coli, GI87082117, Length=336, Percent_Identity=40.1785714285714, Blast_Score=261, Evalue=1e-70,
Organism=Escherichia coli, GI1788905, Length=315, Percent_Identity=42.2222222222222, Blast_Score=255, Evalue=5e-69,
Organism=Escherichia coli, GI1789233, Length=307, Percent_Identity=39.0879478827362, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI1788550, Length=319, Percent_Identity=40.7523510971787, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1789087, Length=317, Percent_Identity=39.1167192429022, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1790299, Length=349, Percent_Identity=36.676217765043, Blast_Score=214, Evalue=9e-57,
Organism=Escherichia coli, GI1786524, Length=322, Percent_Identity=38.5093167701863, Blast_Score=212, Evalue=4e-56,
Organism=Escherichia coli, GI87082152, Length=321, Percent_Identity=36.1370716510903, Blast_Score=205, Evalue=7e-54,
Organism=Escherichia coli, GI87081858, Length=647, Percent_Identity=24.2658423493045, Blast_Score=185, Evalue=7e-48,
Organism=Escherichia coli, GI1787583, Length=247, Percent_Identity=37.6518218623482, Blast_Score=181, Evalue=2e-46,
Organism=Escherichia coli, GI87081872, Length=229, Percent_Identity=41.4847161572052, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1789828, Length=322, Percent_Identity=30.4347826086957, Blast_Score=148, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 70574; Mature: 70574

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLASPFYLHTWKKFVDEGVLDSNRINERISESWYRCKQANVNPHMNKGQKILSSNIFQDQ
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
KKKSEIFLDIAIPQIQNMRKTIDELQMMALLIDPDGYVLSLSGNEQTLKRAKHINFIEGV
HCCCEEEEEEECHHHHHHHHHHHHHHHHHEEECCCCEEEEECCCHHHHHHHHCCCHHHCC
KWTEAAVGTNAIGTALEIEEAIMISGTEHYSVASHSWSCAAAPIHNDDGKLIGVLDFSCP
CHHHHHCCCCCCCCHHEECCEEEEECCCCEEECCCCCCEEECCEECCCCCEEEEEECCCC
IEFSHPYMLGMVTSIAHAIERECSIRVHQNELHLIHRFLDVIDSNEQVVICNHRNVIVSA
CCCCCCHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHCCCCEEEEECCCCEEEEC
SKRVRERVTNWSRMKLEDLMHYGLKTKLEVPVYSNNRMIGKCIYVKENKQEKLFSTSPFI
HHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEEECCCEEEEEEEEEECCCCHHHCCCCCCC
NGITFPGVIGTSDAFQHTLEEIKLVSPTDASVYVCGETGVGKEYVARAIHENSPRKNGPF
CCCCCCCCCCCCHHHHHHHHHCEECCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCE
IAVNCGALPKELMESELFGYAEGAFTGARRQGYKGKFEQADGGTIFLDEIGEVPPEMQVA
EEEECCCCCHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCCEEEEHHHCCCCHHHHHH
LLRVLQERTVTPIGSSKEVPVNIRIITATHKDLLRLVEEGKFRQDLYYRLHVYPLYVPSL
HHHHHHHCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHCCCHHHCEEEEEEEEEEHHHHH
IERKEDIPYFIQHFCERKNWNIVFPKSICNQFSQHTWPGNIRELLNVLERIYILSQGREI
HHHCCCCHHHHHHHHCCCCCCEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHH
CEKQISFLLQTMMRNQHQLELQTENKTEDTLNFREKIQRDSMIEALEKTNGNVSLAAKLL
HHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHH
DVPRSTFYKRMQKYKL
HCCHHHHHHHHHHCCC
>Mature Secondary Structure
MLASPFYLHTWKKFVDEGVLDSNRINERISESWYRCKQANVNPHMNKGQKILSSNIFQDQ
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
KKKSEIFLDIAIPQIQNMRKTIDELQMMALLIDPDGYVLSLSGNEQTLKRAKHINFIEGV
HCCCEEEEEEECHHHHHHHHHHHHHHHHHEEECCCCEEEEECCCHHHHHHHHCCCHHHCC
KWTEAAVGTNAIGTALEIEEAIMISGTEHYSVASHSWSCAAAPIHNDDGKLIGVLDFSCP
CHHHHHCCCCCCCCHHEECCEEEEECCCCEEECCCCCCEEECCEECCCCCEEEEEECCCC
IEFSHPYMLGMVTSIAHAIERECSIRVHQNELHLIHRFLDVIDSNEQVVICNHRNVIVSA
CCCCCCHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHCCCCEEEEECCCCEEEEC
SKRVRERVTNWSRMKLEDLMHYGLKTKLEVPVYSNNRMIGKCIYVKENKQEKLFSTSPFI
HHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEEECCCEEEEEEEEEECCCCHHHCCCCCCC
NGITFPGVIGTSDAFQHTLEEIKLVSPTDASVYVCGETGVGKEYVARAIHENSPRKNGPF
CCCCCCCCCCCCHHHHHHHHHCEECCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCE
IAVNCGALPKELMESELFGYAEGAFTGARRQGYKGKFEQADGGTIFLDEIGEVPPEMQVA
EEEECCCCCHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCCEEEEHHHCCCCHHHHHH
LLRVLQERTVTPIGSSKEVPVNIRIITATHKDLLRLVEEGKFRQDLYYRLHVYPLYVPSL
HHHHHHHCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHCCCHHHCEEEEEEEEEEHHHHH
IERKEDIPYFIQHFCERKNWNIVFPKSICNQFSQHTWPGNIRELLNVLERIYILSQGREI
HHHCCCCHHHHHHHHCCCCCCEEECHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHH
CEKQISFLLQTMMRNQHQLELQTENKTEDTLNFREKIQRDSMIEALEKTNGNVSLAAKLL
HHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHH
DVPRSTFYKRMQKYKL
HCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377; 10368162 [H]