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The map label for this gene is mtnN [H]

Identifier: 52142645

GI number: 52142645

Start: 2712790

End: 2713491

Strand: Reverse

Name: mtnN [H]

Synonym: BCZK2595

Alternate gene names: 52142645

Gene position: 2713491-2712790 (Counterclockwise)

Preceding gene: 52142646

Following gene: 52142647

Centisome position: 51.19

GC content: 35.33

Gene sequence:

>702_bases
ATGAACAGAATCGGCATTATCGGAGCAATGCAAATTGAAATAGACTTACTTTTAGAAAAATTAGTTGTACAAGAGGAACA
AACAATTGCGGGAATGCCTTTTTACGTTGGAGAATTCATGGGAACTGAAGTAATTGTTACAAGATGTGGTGTAGGGAAAG
TAAATGCAGCCGCATGTACGCAAACATTAATTCATAAATTTGATGTAGATGCTATCATCAATACAGGTGTTGCTGGTGGG
TTACACCCGGATGTAAAAGTTGGTGATATCGTTATTTCAACGAATGTTACTCATCATGATGTAAGTAAGACTCAAATGAA
AAACTTATTCCCGTTTCAAGAAGAATTTATCGCAAGTAAGGAATTAGTAGAGTTAGCGCGTAAAGCATGCAATAGTAGTA
ATTTACACATAGAGATTCATGAAGGAAGAATTGTAAGCGGTGAATGTTTTGTTGAAGATTCAAAACTAAAAGCGAAATTA
ATAGATGAATATGCACCGCATTGTACAGAAATGGAAGGTGCAGCAATTGGACATGTTGCCTACATAAATGAAGTACCGTT
TCTCGTAATACGATGTATTTCTGACAGTGCAGACGATGAAGCTCAAATTTCTTATGATGACTTCGCGAAAACGGCCGCAA
ACTATTGTTCAGAAATTATCGTTGAGATGCTTAAAAATATATCAAGTAAAACTGTATTATAA

Upstream 100 bases:

>100_bases
CCACCTTCACGTTTCGCGGATGAAATGAATTGGATAGCTAAAAATTACAGTGCATTACATAGTATATTGGCAGATCTATA
AGAAAAGGGAGATTACATTC

Downstream 100 bases:

>100_bases
TTCAAAAGGAGAGAATGAAATGTTACAAGCATTAATTTTTGATATGGACGGAACGTTATTTCAAACAGATAAAATTTTAG
AATTATCGTTAGATGATACT

Product: bifunctional 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase/phosphatase

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MNRIGIIGAMQIEIDLLLEKLVVQEEQTIAGMPFYVGEFMGTEVIVTRCGVGKVNAAACTQTLIHKFDVDAIINTGVAGG
LHPDVKVGDIVISTNVTHHDVSKTQMKNLFPFQEEFIASKELVELARKACNSSNLHIEIHEGRIVSGECFVEDSKLKAKL
IDEYAPHCTEMEGAAIGHVAYINEVPFLVIRCISDSADDEAQISYDDFAKTAANYCSEIIVEMLKNISSKTVL

Sequences:

>Translated_233_residues
MNRIGIIGAMQIEIDLLLEKLVVQEEQTIAGMPFYVGEFMGTEVIVTRCGVGKVNAAACTQTLIHKFDVDAIINTGVAGG
LHPDVKVGDIVISTNVTHHDVSKTQMKNLFPFQEEFIASKELVELARKACNSSNLHIEIHEGRIVSGECFVEDSKLKAKL
IDEYAPHCTEMEGAAIGHVAYINEVPFLVIRCISDSADDEAQISYDDFAKTAANYCSEIIVEMLKNISSKTVL
>Mature_233_residues
MNRIGIIGAMQIEIDLLLEKLVVQEEQTIAGMPFYVGEFMGTEVIVTRCGVGKVNAAACTQTLIHKFDVDAIINTGVAGG
LHPDVKVGDIVISTNVTHHDVSKTQMKNLFPFQEEFIASKELVELARKACNSSNLHIEIHEGRIVSGECFVEDSKLKAKL
IDEYAPHCTEMEGAAIGHVAYINEVPFLVIRCISDSADDEAQISYDDFAKTAANYCSEIIVEMLKNISSKTVL

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=231, Percent_Identity=36.7965367965368, Blast_Score=124, Evalue=7e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 25533; Mature: 25533

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRIGIIGAMQIEIDLLLEKLVVQEEQTIAGMPFYVGEFMGTEVIVTRCGVGKVNAAACT
CCCEEEEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEECCCCCCCHHHHH
QTLIHKFDVDAIINTGVAGGLHPDVKVGDIVISTNVTHHDVSKTQMKNLFPFQEEFIASK
HHHHHHHCHHHHHHCCCCCCCCCCCEECCEEEECCCCHHHCHHHHHHHCCCHHHHHHHHH
ELVELARKACNSSNLHIEIHEGRIVSGECFVEDSKLKAKLIDEYAPHCTEMEGAAIGHVA
HHHHHHHHHCCCCCEEEEEECCEEECCEEEEECCHHHHHHHHHHCCCCCCCCCCCCHHHH
YINEVPFLVIRCISDSADDEAQISYDDFAKTAANYCSEIIVEMLKNISSKTVL
HHHCCHHEEHEECCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNRIGIIGAMQIEIDLLLEKLVVQEEQTIAGMPFYVGEFMGTEVIVTRCGVGKVNAAACT
CCCEEEEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEEEECCCCCCCHHHHH
QTLIHKFDVDAIINTGVAGGLHPDVKVGDIVISTNVTHHDVSKTQMKNLFPFQEEFIASK
HHHHHHHCHHHHHHCCCCCCCCCCCEECCEEEECCCCHHHCHHHHHHHCCCHHHHHHHHH
ELVELARKACNSSNLHIEIHEGRIVSGECFVEDSKLKAKLIDEYAPHCTEMEGAAIGHVA
HHHHHHHHHCCCCCEEEEEECCEEECCEEEEECCHHHHHHHHHHCCCCCCCCCCCCHHHH
YINEVPFLVIRCISDSADDEAQISYDDFAKTAANYCSEIIVEMLKNISSKTVL
HHHCCHHEEHEECCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA