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The map label for this gene is kstR2 [H]

Identifier: 52142598

GI number: 52142598

Start: 2756697

End: 2757287

Strand: Reverse

Name: kstR2 [H]

Synonym: BCZK2644

Alternate gene names: 52142598

Gene position: 2757287-2756697 (Counterclockwise)

Preceding gene: 52142597

Following gene: 52142599

Centisome position: 52.02

GC content: 31.13

Gene sequence:

>591_bases
ATGAAAAGAATATCGAAAGAACCAGATGTTAGAAGGCAAGAGTTGATGGATATTGGTTTTGAACTATATATGAAAAATGG
TATGAAAGGATTTGGCATAAAAGATGTTGTGAATCATGCTGGTGTAGCAACGGGCTTATTTTATTATTACTTCAAGTCTA
AAGAGAATTTTGTTGATGAAGTATTAAATGATTTTATTGTGAAAAATATGGAGTTAATTGAAGAAATACTTATTTCTAAT
GAACGGTCTGTCATGCAAAAGCTGAAAGATTCTCTAAATATATTTTGGACATTTATCGAAAAATTAGCACCCTATAAAAA
TGTGAGTTCGTTTCAGACGGAACAACATTTTCAACTGGAACAGAAATTATTTACGCGAATGCAGCCATTAATTCGACAAG
TAATCGAAGAAGGGGTGAAAACTGGGATTTTTAATACTGATAACTCATTATTAGCATCAGGATTTATTTTATACGGTCTT
AGCAGTATTGCTCATTCAGAGTTGAATTTGAATCTAGACACGAAGCAAGAAATGGTTAATTTAGTATTAAATACACTACG
ATATGATCAAAGAGAAGGAGAATGTATATGA

Upstream 100 bases:

>100_bases
ATTACTCTTTTTTGTGGAAATTAATATTGACTGAATACAGTTCAGTTGTTTATGATTGAATCAGATTCAGTCGCAGAAAA
AAGATAATAGGAGATAACAT

Downstream 100 bases:

>100_bases
AGATCATGATTGATGGAAACAATATTTCGAATGAACAACTTACAAAGTGGAAAAAAGAACGTATGAAAAAAGTTTTCAAT
ACATTAGGACATAAAGAGCC

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MKRISKEPDVRRQELMDIGFELYMKNGMKGFGIKDVVNHAGVATGLFYYYFKSKENFVDEVLNDFIVKNMELIEEILISN
ERSVMQKLKDSLNIFWTFIEKLAPYKNVSSFQTEQHFQLEQKLFTRMQPLIRQVIEEGVKTGIFNTDNSLLASGFILYGL
SSIAHSELNLNLDTKQEMVNLVLNTLRYDQREGECI

Sequences:

>Translated_196_residues
MKRISKEPDVRRQELMDIGFELYMKNGMKGFGIKDVVNHAGVATGLFYYYFKSKENFVDEVLNDFIVKNMELIEEILISN
ERSVMQKLKDSLNIFWTFIEKLAPYKNVSSFQTEQHFQLEQKLFTRMQPLIRQVIEEGVKTGIFNTDNSLLASGFILYGL
SSIAHSELNLNLDTKQEMVNLVLNTLRYDQREGECI
>Mature_196_residues
MKRISKEPDVRRQELMDIGFELYMKNGMKGFGIKDVVNHAGVATGLFYYYFKSKENFVDEVLNDFIVKNMELIEEILISN
ERSVMQKLKDSLNIFWTFIEKLAPYKNVSSFQTEQHFQLEQKLFTRMQPLIRQVIEEGVKTGIFNTDNSLLASGFILYGL
SSIAHSELNLNLDTKQEMVNLVLNTLRYDQREGECI

Specific function: Controls the expression of a small regulon that may play a role in the utilization of cholesterol [H]

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22839; Mature: 22839

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRISKEPDVRRQELMDIGFELYMKNGMKGFGIKDVVNHAGVATGLFYYYFKSKENFVDE
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHH
VLNDFIVKNMELIEEILISNERSVMQKLKDSLNIFWTFIEKLAPYKNVSSFQTEQHFQLE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
QKLFTRMQPLIRQVIEEGVKTGIFNTDNSLLASGFILYGLSSIAHSELNLNLDTKQEMVN
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LVLNTLRYDQREGECI
HHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKRISKEPDVRRQELMDIGFELYMKNGMKGFGIKDVVNHAGVATGLFYYYFKSKENFVDE
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHH
VLNDFIVKNMELIEEILISNERSVMQKLKDSLNIFWTFIEKLAPYKNVSSFQTEQHFQLE
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
QKLFTRMQPLIRQVIEEGVKTGIFNTDNSLLASGFILYGLSSIAHSELNLNLDTKQEMVN
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LVLNTLRYDQREGECI
HHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA