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The map label for this gene is paiA [H]

Identifier: 52142288

GI number: 52142288

Start: 3085181

End: 3085699

Strand: Direct

Name: paiA [H]

Synonym: BCZK2952

Alternate gene names: 52142288

Gene position: 3085181-3085699 (Clockwise)

Preceding gene: 52142291

Following gene: 52142289

Centisome position: 58.2

GC content: 31.02

Gene sequence:

>519_bases
ATGACTACACATATAGAAAAGTGCACCCTTAAAGATATACACAAACTTCAAGAAATTAGTTATGAAACATTTAATGAAAC
TTTTAAACATCAAAATTCACCCGAAAATATGCATCATTATTTGGAAAAGGCATTTAACTTAAAGCAATTAGAAAAAGAAC
TATCCAATATCTCTTCTCAATTCTTTTTTGTCTACTTCAACGATGAAATTGCTGGGTATCTGAAGATCAATACTGATGAT
GCTCAGTCTGAAGAAATGGACGATGAATCACTTGAAGTCGAGAGAATTTATATAAAGAGCTCCTTTCAAAAACATGGTCT
TGGCAAATATCTACTAAATAACGCTATCGAAATTGCAATAGCAAATAATAAAAAGAATATTTGGCTAGGCGTATGGGAAA
AAAATGAAAATGCTATTGCTTTTTATAAAAAATTAGGGTTTGTACCAGCTGGCTCTCACTCCTTTTATATGGGAGATGAT
GAACAAGTTGACCTTATCATGATTAAAACACTCATATAA

Upstream 100 bases:

>100_bases
CTTCTTCAAAGAGTAAGAAAAAATATAGAAAAAGATTGGGAATTTGTAAAAAAGGGAAATAAGAGAGATTATTGATTATA
TAAAGGAGCGAACTATTAAT

Downstream 100 bases:

>100_bases
ATTTTTTGAGAGGTGGGCTATTATGTATATTCCAAAGTATTTTAAAGTCACAAATGTTGATGAAATTTGGGGTTTTGTTC
AAAAAAACTCTTTTGGAACA

Product: protease synthase and sporulation negative regulatory protein PAI 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MTTHIEKCTLKDIHKLQEISYETFNETFKHQNSPENMHHYLEKAFNLKQLEKELSNISSQFFFVYFNDEIAGYLKINTDD
AQSEEMDDESLEVERIYIKSSFQKHGLGKYLLNNAIEIAIANNKKNIWLGVWEKNENAIAFYKKLGFVPAGSHSFYMGDD
EQVDLIMIKTLI

Sequences:

>Translated_172_residues
MTTHIEKCTLKDIHKLQEISYETFNETFKHQNSPENMHHYLEKAFNLKQLEKELSNISSQFFFVYFNDEIAGYLKINTDD
AQSEEMDDESLEVERIYIKSSFQKHGLGKYLLNNAIEIAIANNKKNIWLGVWEKNENAIAFYKKLGFVPAGSHSFYMGDD
EQVDLIMIKTLI
>Mature_171_residues
TTHIEKCTLKDIHKLQEISYETFNETFKHQNSPENMHHYLEKAFNLKQLEKELSNISSQFFFVYFNDEIAGYLKINTDDA
QSEEMDDESLEVERIYIKSSFQKHGLGKYLLNNAIEIAIANNKKNIWLGVWEKNENAIAFYKKLGFVPAGSHSFYMGDDE
QVDLIMIKTLI

Specific function: Possesses N1-acetyltransferase activity toward polyamine substrates including spermidine and spermine. Can acetylate both spermidine and spermine. In this way it may function in regulating intracellular polyamine concentrations and/or binding capabilities

COG id: COG0454

COG function: function code KR; Histone acetyltransferase HPA2 and related acetyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181 [H]

Pfam domain/function: PF00583 Acetyltransf_1 [H]

EC number: NA

Molecular weight: Translated: 20126; Mature: 19995

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTHIEKCTLKDIHKLQEISYETFNETFKHQNSPENMHHYLEKAFNLKQLEKELSNISSQ
CCCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCE
FFFVYFNDEIAGYLKINTDDAQSEEMDDESLEVERIYIKSSFQKHGLGKYLLNNAIEIAI
EEEEEECCCEEEEEEEECCCCCCCCCCCCCCEEEEEEEECCHHHCCCHHHHHCCEEEEEE
ANNKKNIWLGVWEKNENAIAFYKKLGFVPAGSHSFYMGDDEQVDLIMIKTLI
ECCCCEEEEEEEECCCCEEEEEHHHCCCCCCCCEEEECCCCCEEEEEEEECC
>Mature Secondary Structure 
TTHIEKCTLKDIHKLQEISYETFNETFKHQNSPENMHHYLEKAFNLKQLEKELSNISSQ
CCCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHCCCCE
FFFVYFNDEIAGYLKINTDDAQSEEMDDESLEVERIYIKSSFQKHGLGKYLLNNAIEIAI
EEEEEECCCEEEEEEEECCCCCCCCCCCCCCEEEEEEEECCHHHCCCHHHHHCCEEEEEE
ANNKKNIWLGVWEKNENAIAFYKKLGFVPAGSHSFYMGDDEQVDLIMIKTLI
ECCCCEEEEEEEECCCCEEEEEHHHCCCCCCCCEEEECCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2108124; 9384377 [H]