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The map label for this gene is sigM [H]

Identifier: 52142270

GI number: 52142270

Start: 3103583

End: 3104083

Strand: Reverse

Name: sigM [H]

Synonym: BCZK2972

Alternate gene names: 52142270

Gene position: 3104083-3103583 (Counterclockwise)

Preceding gene: 52142269

Following gene: 52142272

Centisome position: 58.56

GC content: 32.14

Gene sequence:

>501_bases
ATGGAAATTGAAGAAATATATAAGATTTATATAAACGATGTGTACCGATATTTATTTTCCCTTTCTCGTAGCCATCATGT
AGCGGAGGACTTGATGCAGGAGACTTTTTATCGTGCGTATCTTTATCTAGAAGACTATGAAAACCAAAAGGTAAAATCAT
GGCTCTTTAAAGTGGCATATCATACGTTTATTGATTTTGTTAGAAAAGAGAAAAAAGTATCTTTTGTAGGAACGGAGGAA
TTAGAGGCAATTCAAGCAGGTGAATCTACAGAAGAGTATGTAGTCGCAAAAAATAGTTATGAAAAATTAATTCAGATTAT
TCATACTTTACCTGTGATAGAGGCGCAAGCTATTTTATTATGTGACGTACATGAATTAACGTACGAAGAGGGTGCTTCTG
TATTAGATTTAAAGTTAAACACGTATAAAAGTCACATATTTCGTGGGAGAAAAAGATTAAAACAATTATTAAAGGAGGAA
AAGAGTCAAAATGACAAATGA

Upstream 100 bases:

>100_bases
TAGAATGTATAAGGGTTATTTTTTTATAAAAAAAGATAAAGGAAAAATAATGCAACTTTTTAACGCGTTTATTCGTGTTA
TATGTGAAAGGAGGAGGGGG

Downstream 100 bases:

>100_bases
TAAACCTCATTCTGAACAAGAAGATTATAAAGACTTGTTGCAAGAAGCTCTTCATCAAAGACCTGCATCTCTTCCTGATG
GAAAACAGGAGCAAGTGTTG

Product: RNA polymerase sigma factor SigM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MEIEEIYKIYINDVYRYLFSLSRSHHVAEDLMQETFYRAYLYLEDYENQKVKSWLFKVAYHTFIDFVRKEKKVSFVGTEE
LEAIQAGESTEEYVVAKNSYEKLIQIIHTLPVIEAQAILLCDVHELTYEEGASVLDLKLNTYKSHIFRGRKRLKQLLKEE
KSQNDK

Sequences:

>Translated_166_residues
MEIEEIYKIYINDVYRYLFSLSRSHHVAEDLMQETFYRAYLYLEDYENQKVKSWLFKVAYHTFIDFVRKEKKVSFVGTEE
LEAIQAGESTEEYVVAKNSYEKLIQIIHTLPVIEAQAILLCDVHELTYEEGASVLDLKLNTYKSHIFRGRKRLKQLLKEE
KSQNDK
>Mature_166_residues
MEIEEIYKIYINDVYRYLFSLSRSHHVAEDLMQETFYRAYLYLEDYENQKVKSWLFKVAYHTFIDFVRKEKKVSFVGTEE
LEAIQAGESTEEYVVAKNSYEKLIQIIHTLPVIEAQAILLCDVHELTYEEGASVLDLKLNTYKSHIFRGRKRLKQLLKEE
KSQNDK

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor may be involved in the maintenance of membrane and cell wall integrity in response to salt, acid and e

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014296
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 19801; Mature: 19801

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIEEIYKIYINDVYRYLFSLSRSHHVAEDLMQETFYRAYLYLEDYENQKVKSWLFKVAY
CCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
HTFIDFVRKEKKVSFVGTEELEAIQAGESTEEYVVAKNSYEKLIQIIHTLPVIEAQAILL
HHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHEEECHHHHHHHHHHHHHHHHHHHHHHH
CDVHELTYEEGASVLDLKLNTYKSHIFRGRKRLKQLLKEEKSQNDK
HHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEIEEIYKIYINDVYRYLFSLSRSHHVAEDLMQETFYRAYLYLEDYENQKVKSWLFKVAY
CCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
HTFIDFVRKEKKVSFVGTEELEAIQAGESTEEYVVAKNSYEKLIQIIHTLPVIEAQAILL
HHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHEEECHHHHHHHHHHHHHHHHHHHHHHH
CDVHELTYEEGASVLDLKLNTYKSHIFRGRKRLKQLLKEEKSQNDK
HHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 12775685; 10216858 [H]