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The map label for this gene is adp [C]

Identifier: 52142220

GI number: 52142220

Start: 3152639

End: 3154801

Strand: Reverse

Name: adp [C]

Synonym: BCZK3022

Alternate gene names: 52142220

Gene position: 3154801-3152639 (Counterclockwise)

Preceding gene: 52142215

Following gene: 52142221

Centisome position: 59.51

GC content: 38.42

Gene sequence:

>2163_bases
ATGAAGTCATTTATCTTAAAAAAAGGAACAGCCCTTACTTTAACAGGGGCAATATTGGTTGGAGCGTTAGCGATACCTTC
TTTTGAAAACGTACATGCGGTAAACAAAAGGACATCAATTGAACAAGTTATTGATAAAGCTGCCGATGCAAAGAATATTC
CAGGAGTTATTGTTACTGTGAAAAATGGAGAGACAAGTTGGGCATATGCTTCTGGTGAAGGTAATATTGAGAGAAATCAT
AAAGTAGATGCTGATTCTGCTTTTAGAATTGGGAGCACAACGAAGAGCTTTGTAGCTACAGTAGTATTGCAGCTTGCGGG
TGAAAAGAAGTTAAGTCTTGATGATACGGTAGAGAAATGGTTGCCAGGACTTATTAAAGGGAAAGGCTATGATGGCAGCA
AAATTACGATTCGCCAACTATTAAATCATACAAGTGGAATTGCTGATTACTTGACTTCAGATCTTAAAGAGAAATTAATG
GAGAATCCAAGTGAGAATTATACAGCGGAACAATTAATTTCTCGTGCTTTACAATTGGAACCAGTAAAAGGATGGTCATA
CTCGAATACGAATATGGTTATTATTGGATTAATTATTCAGAAAGTAACAGGGGAATCATATGCTGAGCAGATACAAAAAC
GAATTATTAATCCTCTTAGTTTAAAAGAAACAGTTCTTCCTGGAAGCTCAATGGATATTCCGAAAAAAAATGCCCGTGGC
TATTTAAATACGGGAGATAAATTAGTAGATATTACTTTGTTTAATCCATCGTTTGCTAATGCTAGTGGTGAAATGATTTC
GACAGGAGAAGATATGACAACGTTCTTCCGTGCCTTATTAGGTGGTAAATTACTTACACCGGAAATGCAGAAGGAGATGG
TGACTCACACAGTAGATACCCCATTAGGAAAGTATGGGCTTGGTATTCACGCAACAAAATTACCAGATGGTACTGAAGTA
TGGGGACATGGTGGTGGTATCCCTGGTTTTACTAACTTTGCTGGTGGAACGAAAGATGGTCAGCATGTTATCTCGATAAA
TATTAATGTATTAGGCGCAGAGAAACAGATTAATAATATTTTAGCTTCAGAATTTGCGGCAAAATCAAAAAAGGAACCCA
CTAATAAGGAAAAGAAAAGCAAACATCGAGAGGAAGTACAAAATGTAATGGATCAAGTAGTAACGAATAAAAAAATTCCT
AGTGTTATAGCTGGTGGATTAAAGGATGGAAAGCGTTGGTCGTATGCTACCGGAACAGCTAGTTACGAGATGCCACGCCC
TGTAGAACCGAATTTTTCGTTCCGTATCGGAAGCATAACGAAGACATTCACTGCTTCTGTTGTACTGCAATTGGCTGAAG
AGAAACAATTAAACCTTGATGATACAGTTGAAAAATGGTTGCCGGGAGTTGTGCAGGGTAACGGATATGATGGGAGTAAA
ATTACAATTCGTCAGTTATTAAACCATACAAGTGGGATTGCAGCATATACTGATTTAGATATGCGAGATATTACATTGCC
TCAAAACCCATTTCGTTATTATAGTACCGATGAGCTCATAAGTTTAGCGCTTGCAAAGCCGCCTGTATTTGCACCAGGGG
AGGGCTGGGACTATTCGAACACAAATACTGTTATAGCCGGGGAAATTATTCGAAAGGTAACAGGAGATACGTATGCGGAG
CAAATTAGAAAAAGATTTATTGAACCGCTCGGGTTAAAAGAAACATTCGTAATGGAAGCAAGTTCGCACATACTGGGTAA
GCATGCTAATGGTTATAACATGGATAGATCAGGTCGTTTATATGATTTGACAGAAATTAATCAGTCATGGGCAAATGCAG
CTGGAGATATGGTTTCAACAGTGGAAGATTTGACTACATTCTTCAGTGCACTGTTAGGTGGGAAGCTCTTAAATCAAGAA
CTAATGAATCAGATGTTAACAACGGTAGATTCACCTATAGGTAAGGTTGGACTGGGAGTTTATGAAGAGAAAACACCAGA
CGGGCAATCGTATTGGGGACATGCTGGTGGGACTTTTGGATTTGAAACAAGGGTCGGTGGACCTATTGGAGGAGAACATA
TTTTAGTAACTGCTATTAATGCAGTAGGTCCAGAAGTCATTACAGGCAGGGATAAAATATTTAATAAAGAATTTGGACGT
TAA

Upstream 100 bases:

>100_bases
ATAAATTAAAACGTTTTGTCACTATGTGATTTAACAATATTGAAGGTAAGGTAAGGGAGTGAGGCAACAGAAAAATTTAA
AATAATAGGAGCGATGCATA

Downstream 100 bases:

>100_bases
ATGAAAAATCGACATCGATCCTTCCGTTTGAAGGCTCGATGTCGATTTTTTTTATCCCGCATTAACGGGCAGTACAACCC
CCACATCAAAATTCAGCGGA

Product: alkaline D-peptidase and alkaline D-peptidase fusion

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase [H]

Number of amino acids: Translated: 720; Mature: 720

Protein sequence:

>720_residues
MKSFILKKGTALTLTGAILVGALAIPSFENVHAVNKRTSIEQVIDKAADAKNIPGVIVTVKNGETSWAYASGEGNIERNH
KVDADSAFRIGSTTKSFVATVVLQLAGEKKLSLDDTVEKWLPGLIKGKGYDGSKITIRQLLNHTSGIADYLTSDLKEKLM
ENPSENYTAEQLISRALQLEPVKGWSYSNTNMVIIGLIIQKVTGESYAEQIQKRIINPLSLKETVLPGSSMDIPKKNARG
YLNTGDKLVDITLFNPSFANASGEMISTGEDMTTFFRALLGGKLLTPEMQKEMVTHTVDTPLGKYGLGIHATKLPDGTEV
WGHGGGIPGFTNFAGGTKDGQHVISININVLGAEKQINNILASEFAAKSKKEPTNKEKKSKHREEVQNVMDQVVTNKKIP
SVIAGGLKDGKRWSYATGTASYEMPRPVEPNFSFRIGSITKTFTASVVLQLAEEKQLNLDDTVEKWLPGVVQGNGYDGSK
ITIRQLLNHTSGIAAYTDLDMRDITLPQNPFRYYSTDELISLALAKPPVFAPGEGWDYSNTNTVIAGEIIRKVTGDTYAE
QIRKRFIEPLGLKETFVMEASSHILGKHANGYNMDRSGRLYDLTEINQSWANAAGDMVSTVEDLTTFFSALLGGKLLNQE
LMNQMLTTVDSPIGKVGLGVYEEKTPDGQSYWGHAGGTFGFETRVGGPIGGEHILVTAINAVGPEVITGRDKIFNKEFGR

Sequences:

>Translated_720_residues
MKSFILKKGTALTLTGAILVGALAIPSFENVHAVNKRTSIEQVIDKAADAKNIPGVIVTVKNGETSWAYASGEGNIERNH
KVDADSAFRIGSTTKSFVATVVLQLAGEKKLSLDDTVEKWLPGLIKGKGYDGSKITIRQLLNHTSGIADYLTSDLKEKLM
ENPSENYTAEQLISRALQLEPVKGWSYSNTNMVIIGLIIQKVTGESYAEQIQKRIINPLSLKETVLPGSSMDIPKKNARG
YLNTGDKLVDITLFNPSFANASGEMISTGEDMTTFFRALLGGKLLTPEMQKEMVTHTVDTPLGKYGLGIHATKLPDGTEV
WGHGGGIPGFTNFAGGTKDGQHVISININVLGAEKQINNILASEFAAKSKKEPTNKEKKSKHREEVQNVMDQVVTNKKIP
SVIAGGLKDGKRWSYATGTASYEMPRPVEPNFSFRIGSITKTFTASVVLQLAEEKQLNLDDTVEKWLPGVVQGNGYDGSK
ITIRQLLNHTSGIAAYTDLDMRDITLPQNPFRYYSTDELISLALAKPPVFAPGEGWDYSNTNTVIAGEIIRKVTGDTYAE
QIRKRFIEPLGLKETFVMEASSHILGKHANGYNMDRSGRLYDLTEINQSWANAAGDMVSTVEDLTTFFSALLGGKLLNQE
LMNQMLTTVDSPIGKVGLGVYEEKTPDGQSYWGHAGGTFGFETRVGGPIGGEHILVTAINAVGPEVITGRDKIFNKEFGR
>Mature_720_residues
MKSFILKKGTALTLTGAILVGALAIPSFENVHAVNKRTSIEQVIDKAADAKNIPGVIVTVKNGETSWAYASGEGNIERNH
KVDADSAFRIGSTTKSFVATVVLQLAGEKKLSLDDTVEKWLPGLIKGKGYDGSKITIRQLLNHTSGIADYLTSDLKEKLM
ENPSENYTAEQLISRALQLEPVKGWSYSNTNMVIIGLIIQKVTGESYAEQIQKRIINPLSLKETVLPGSSMDIPKKNARG
YLNTGDKLVDITLFNPSFANASGEMISTGEDMTTFFRALLGGKLLTPEMQKEMVTHTVDTPLGKYGLGIHATKLPDGTEV
WGHGGGIPGFTNFAGGTKDGQHVISININVLGAEKQINNILASEFAAKSKKEPTNKEKKSKHREEVQNVMDQVVTNKKIP
SVIAGGLKDGKRWSYATGTASYEMPRPVEPNFSFRIGSITKTFTASVVLQLAEEKQLNLDDTVEKWLPGVVQGNGYDGSK
ITIRQLLNHTSGIAAYTDLDMRDITLPQNPFRYYSTDELISLALAKPPVFAPGEGWDYSNTNTVIAGEIIRKVTGDTYAE
QIRKRFIEPLGLKETFVMEASSHILGKHANGYNMDRSGRLYDLTEINQSWANAAGDMVSTVEDLTTFFSALLGGKLLNQE
LMNQMLTTVDSPIGKVGLGVYEEKTPDGQSYWGHAGGTFGFETRVGGPIGGEHILVTAINAVGPEVITGRDKIFNKEFGR

Specific function: Catalyzes distinct carboxypeptidation and transpeptidation reactions during the last stages of wall peptidoglycan synthesis. Mistaking a beta-lactam antibiotic molecule for a normal substrate (i.e., a D-alanyl-D-alanine- terminated peptide), it becomes im

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S12 family [H]

Homologues:

Organism=Escherichia coli, GI1786574, Length=219, Percent_Identity=24.2009132420091, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1790593, Length=318, Percent_Identity=22.9559748427673, Blast_Score=62, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI115533026, Length=271, Percent_Identity=26.5682656826568, Blast_Score=90, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17565630, Length=291, Percent_Identity=25.7731958762887, Blast_Score=73, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17550934, Length=174, Percent_Identity=29.3103448275862, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 78401; Mature: 78401

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSFILKKGTALTLTGAILVGALAIPSFENVHAVNKRTSIEQVIDKAADAKNIPGVIVTV
CCCCEECCCCEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
KNGETSWAYASGEGNIERNHKVDADSAFRIGSTTKSFVATVVLQLAGEKKLSLDDTVEKW
ECCCCCEEEECCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHH
LPGLIKGKGYDGSKITIRQLLNHTSGIADYLTSDLKEKLMENPSENYTAEQLISRALQLE
CCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCC
PVKGWSYSNTNMVIIGLIIQKVTGESYAEQIQKRIINPLSLKETVLPGSSMDIPKKNARG
CCCCCCCCCCCEEEEEEHHHHHCCHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCC
YLNTGDKLVDITLFNPSFANASGEMISTGEDMTTFFRALLGGKLLTPEMQKEMVTHTVDT
CCCCCCEEEEEEEECCCCCCCCCCEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
PLGKYGLGIHATKLPDGTEVWGHGGGIPGFTNFAGGTKDGQHVISININVLGAEKQINNI
CCCCCCCCEEEEECCCCCEECCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECHHHHHHH
LASEFAAKSKKEPTNKEKKSKHREEVQNVMDQVVTNKKIPSVIAGGLKDGKRWSYATGTA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCEEEECCCC
SYEMPRPVEPNFSFRIGSITKTFTASVVLQLAEEKQLNLDDTVEKWLPGVVQGNGYDGSK
CCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEECCCCCCCH
ITIRQLLNHTSGIAAYTDLDMRDITLPQNPFRYYSTDELISLALAKPPVFAPGEGWDYSN
HHHHHHHCCCCCEEEEECCCCEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCC
TNTVIAGEIIRKVTGDTYAEQIRKRFIEPLGLKETFVMEASSHILGKHANGYNMDRSGRL
CCEEEHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCE
YDLTEINQSWANAAGDMVSTVEDLTTFFSALLGGKLLNQELMNQMLTTVDSPIGKVGLGV
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHCCCC
YEEKTPDGQSYWGHAGGTFGFETRVGGPIGGEHILVTAINAVGPEVITGRDKIFNKEFGR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MKSFILKKGTALTLTGAILVGALAIPSFENVHAVNKRTSIEQVIDKAADAKNIPGVIVTV
CCCCEECCCCEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
KNGETSWAYASGEGNIERNHKVDADSAFRIGSTTKSFVATVVLQLAGEKKLSLDDTVEKW
ECCCCCEEEECCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHH
LPGLIKGKGYDGSKITIRQLLNHTSGIADYLTSDLKEKLMENPSENYTAEQLISRALQLE
CCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCC
PVKGWSYSNTNMVIIGLIIQKVTGESYAEQIQKRIINPLSLKETVLPGSSMDIPKKNARG
CCCCCCCCCCCEEEEEEHHHHHCCHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCC
YLNTGDKLVDITLFNPSFANASGEMISTGEDMTTFFRALLGGKLLTPEMQKEMVTHTVDT
CCCCCCEEEEEEEECCCCCCCCCCEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
PLGKYGLGIHATKLPDGTEVWGHGGGIPGFTNFAGGTKDGQHVISININVLGAEKQINNI
CCCCCCCCEEEEECCCCCEECCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECHHHHHHH
LASEFAAKSKKEPTNKEKKSKHREEVQNVMDQVVTNKKIPSVIAGGLKDGKRWSYATGTA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCEEEECCCC
SYEMPRPVEPNFSFRIGSITKTFTASVVLQLAEEKQLNLDDTVEKWLPGVVQGNGYDGSK
CCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEECCCCCCCH
ITIRQLLNHTSGIAAYTDLDMRDITLPQNPFRYYSTDELISLALAKPPVFAPGEGWDYSN
HHHHHHHCCCCCEEEEECCCCEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCC
TNTVIAGEIIRKVTGDTYAEQIRKRFIEPLGLKETFVMEASSHILGKHANGYNMDRSGRL
CCEEEHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCE
YDLTEINQSWANAAGDMVSTVEDLTTFFSALLGGKLLNQELMNQMLTTVDSPIGKVGLGV
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHCCCC
YEEKTPDGQSYWGHAGGTFGFETRVGGPIGGEHILVTAINAVGPEVITGRDKIFNKEFGR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3830154; 7925404; 3030739; 2175384; 2386365; 3997832; 7490745 [H]