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The map label for this gene is fabG [H]

Identifier: 52142209

GI number: 52142209

Start: 3163682

End: 3164440

Strand: Reverse

Name: fabG [H]

Synonym: BCZK3032

Alternate gene names: 52142209

Gene position: 3164440-3163682 (Counterclockwise)

Preceding gene: 52142210

Following gene: 52142211

Centisome position: 59.7

GC content: 39.92

Gene sequence:

>759_bases
GTGAAGAAAATAGCAATTGTAACAGGGGCCACTCGTCTGAATGGAATTGGTGCAGTTGTATGCAAGGTGCTTGCTCAAAA
AGGAATAGACATTTTTTTCACGTACTGGTCTCAGTATGATAAAGCGATGCCGTGGGGAATGCATGACAAAGAGCCCTTTT
TGTTGAAAGAGGAGATTGAAAGTTACGGTGTTCGATGTGAAATGGCAGAAATCAACTTATCGCAGTCGTATTCATCAAAT
CGTTTGTTTTATATGGTATCAGAACGGTTAGGTGATCCATCTATTTTAATTAATAATGCAGCGTATGCTACTCATACGAG
AATTGAGGAATTAAATGTAGAACAGTTAGATAAACATTATACGGTTAATGTTCGGGCTACTATGTTATTAAGCTCATTAT
TTATAAAACATTATGCAAGCAAGACGAGTGGGAGTATTATTAATCTTACTTCAGGACAGTCACTCGGGCCAATGCCTGAT
GAACTAGCATACGTAGCAACGAAAGGAGCAATTGAAGCATTTACAAAATCAGTAGCACCAGTTGCGATGGAGAAGGGGAT
TACAGTAAATGCTGTTGATCCAGGACCGACGAATACAGGATGGATTACAGAGGAGCTGAAGCATCATTTAGTATGGAAGT
TCCCGCAAGGTAAAGTAGGAGAGCCGGTGGATGCTGCGCGCTTAATATCTTTTTTAGTAAGTGAAGAAGCGAAATGGATT
ACTGGGCAAGTTATTCATTCGAACGGTGGTTACTCATAA

Upstream 100 bases:

>100_bases
TTTTAAAATTAGGTGCAGAACGTATATTGTCAAATATTGAATAAAAAGATAGATCCTCTGTATTCGTGCAGAGGATCTAT
CCATAGGTGGAGGAGAAAAG

Downstream 100 bases:

>100_bases
ATATATTATGTTAACAATTGTTGAGAAACAAAAAAACGAAAGAAAATTTTATTTTTTTGTATAAATAAAATGTCAAGAAA
GATAAAAATTTGATAGAAGA

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MKKIAIVTGATRLNGIGAVVCKVLAQKGIDIFFTYWSQYDKAMPWGMHDKEPFLLKEEIESYGVRCEMAEINLSQSYSSN
RLFYMVSERLGDPSILINNAAYATHTRIEELNVEQLDKHYTVNVRATMLLSSLFIKHYASKTSGSIINLTSGQSLGPMPD
ELAYVATKGAIEAFTKSVAPVAMEKGITVNAVDPGPTNTGWITEELKHHLVWKFPQGKVGEPVDAARLISFLVSEEAKWI
TGQVIHSNGGYS

Sequences:

>Translated_252_residues
MKKIAIVTGATRLNGIGAVVCKVLAQKGIDIFFTYWSQYDKAMPWGMHDKEPFLLKEEIESYGVRCEMAEINLSQSYSSN
RLFYMVSERLGDPSILINNAAYATHTRIEELNVEQLDKHYTVNVRATMLLSSLFIKHYASKTSGSIINLTSGQSLGPMPD
ELAYVATKGAIEAFTKSVAPVAMEKGITVNAVDPGPTNTGWITEELKHHLVWKFPQGKVGEPVDAARLISFLVSEEAKWI
TGQVIHSNGGYS
>Mature_252_residues
MKKIAIVTGATRLNGIGAVVCKVLAQKGIDIFFTYWSQYDKAMPWGMHDKEPFLLKEEIESYGVRCEMAEINLSQSYSSN
RLFYMVSERLGDPSILINNAAYATHTRIEELNVEQLDKHYTVNVRATMLLSSLFIKHYASKTSGSIINLTSGQSLGPMPD
ELAYVATKGAIEAFTKSVAPVAMEKGITVNAVDPGPTNTGWITEELKHHLVWKFPQGKVGEPVDAARLISFLVSEEAKWI
TGQVIHSNGGYS

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=254, Percent_Identity=26.7716535433071, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI40254992, Length=250, Percent_Identity=24.4, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI66933014, Length=207, Percent_Identity=26.0869565217391, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI7705925, Length=168, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI15277342, Length=268, Percent_Identity=25.7462686567164, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1788459, Length=255, Percent_Identity=30.5882352941176, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787335, Length=254, Percent_Identity=27.9527559055118, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=28.968253968254, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082160, Length=254, Percent_Identity=27.5590551181102, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI87082100, Length=264, Percent_Identity=25, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI2367175, Length=261, Percent_Identity=26.4367816091954, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789208, Length=255, Percent_Identity=26.2745098039216, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790717, Length=202, Percent_Identity=22.7722772277228, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786812, Length=177, Percent_Identity=27.1186440677966, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=23.8683127572016, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=268, Percent_Identity=27.6119402985075, Blast_Score=90, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI115534694, Length=256, Percent_Identity=25.78125, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17562906, Length=269, Percent_Identity=27.1375464684015, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17538486, Length=270, Percent_Identity=27.7777777777778, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17531453, Length=275, Percent_Identity=30.1818181818182, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=269, Percent_Identity=26.3940520446097, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17560676, Length=254, Percent_Identity=24.8031496062992, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=272, Percent_Identity=25.3676470588235, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=271, Percent_Identity=27.6752767527675, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=272, Percent_Identity=27.5735294117647, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=258, Percent_Identity=26.7441860465116, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=194, Percent_Identity=29.3814432989691, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=261, Percent_Identity=24.1379310344828, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=255, Percent_Identity=27.4509803921569, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=200, Percent_Identity=27.5, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=262, Percent_Identity=24.8091603053435, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=261, Percent_Identity=26.0536398467433, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=202, Percent_Identity=26.7326732673267, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=269, Percent_Identity=26.0223048327138, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=24.9056603773585, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=198, Percent_Identity=27.7777777777778, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=25.1908396946565, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=274, Percent_Identity=26.2773722627737, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17561272, Length=200, Percent_Identity=26.5, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI23397609, Length=258, Percent_Identity=27.1317829457364, Blast_Score=97, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24639444, Length=258, Percent_Identity=25.968992248062, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21355319, Length=258, Percent_Identity=27.906976744186, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21357041, Length=263, Percent_Identity=30.7984790874525, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24644339, Length=188, Percent_Identity=30.8510638297872, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28571526, Length=169, Percent_Identity=33.1360946745562, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24644337, Length=169, Percent_Identity=28.9940828402367, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24643142, Length=258, Percent_Identity=25.968992248062, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 27847; Mature: 27847

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIAIVTGATRLNGIGAVVCKVLAQKGIDIFFTYWSQYDKAMPWGMHDKEPFLLKEEIE
CCEEEEEECCHHHCHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCCCCCCCCCHHHHHHH
SYGVRCEMAEINLSQSYSSNRLFYMVSERLGDPSILINNAAYATHTRIEELNVEQLDKHY
HHCCEEEEEEECCCCCCCCCEEEEEEHHHCCCCEEEEECCCHHHHHHHHHCCHHHHCCEE
TVNVRATMLLSSLFIKHYASKTSGSIINLTSGQSLGPMPDELAYVATKGAIEAFTKSVAP
EEEHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
VAMEKGITVNAVDPGPTNTGWITEELKHHLVWKFPQGKVGEPVDAARLISFLVSEEAKWI
HHHHCCCEEEECCCCCCCCCCHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHCCCCEE
TGQVIHSNGGYS
EEEEEECCCCCC
>Mature Secondary Structure
MKKIAIVTGATRLNGIGAVVCKVLAQKGIDIFFTYWSQYDKAMPWGMHDKEPFLLKEEIE
CCEEEEEECCHHHCHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCCCCCCCCCHHHHHHH
SYGVRCEMAEINLSQSYSSNRLFYMVSERLGDPSILINNAAYATHTRIEELNVEQLDKHY
HHCCEEEEEEECCCCCCCCCEEEEEEHHHCCCCEEEEECCCHHHHHHHHHCCHHHHCCEE
TVNVRATMLLSSLFIKHYASKTSGSIINLTSGQSLGPMPDELAYVATKGAIEAFTKSVAP
EEEHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
VAMEKGITVNAVDPGPTNTGWITEELKHHLVWKFPQGKVGEPVDAARLISFLVSEEAKWI
HHHHCCCEEEECCCCCCCCCCHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHCCCCEE
TGQVIHSNGGYS
EEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]