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The map label for this gene is trpS [H]

Identifier: 52142190

GI number: 52142190

Start: 3182614

End: 3183612

Strand: Reverse

Name: trpS [H]

Synonym: BCZK3053

Alternate gene names: 52142190

Gene position: 3183612-3182614 (Counterclockwise)

Preceding gene: 52142187

Following gene: 52142189

Centisome position: 60.06

GC content: 38.14

Gene sequence:

>999_bases
ATGAGTGACAAAATAATGTTAACAGGAATTAAGCCGACAGGTTATCCGCATTTAGGAAATTATATTGGTGCAATTAAACC
TGCGTTGCAAATGTCAAAGAAGAATGAAGGAAAAGCATTGTATTTTATAGCAGATTATCACGCGTTAAATGCTGTGCATA
ATCAGAGCCAGTTTAGTAGCTATACGAAAGAGGTAGCTGCTACTTGGTTATCGCTTGGACTTGGAGAAGATGTTATATTT
TACCGACAAACAGAAGTGCCGGAGATTCTAGAATTAGCTTGGATATTAGCTTGCCTAACTCCGAAAGGGCTTATGAACCG
TGCTCATGCGTATAAAGCGAAGGTGGAGCAAAATAAAGAAGCGGGTTTAGAGGTCGATGCAGGAGTGAATATGGGATTAT
ATACGTATCCGATCTTAATGGCAGCTGACATATTGCTATTTCAGGCTACATATGTGCCAGTCGGAAAAGACCAAATTCAG
CATATTGAAATCGCGCGTGATATTGCGACGTATTTTAATCATACTTTTGGCAGGACATTTACACTTCCGGAGTATGTCAT
ACAAGAAGAGGGTGCAATATTACCAGGGCTTGATGGAAGAAAGATGAGTAAAAGTTATGGGAATGTGATCCCATTATTTG
CAGAGCAAGAAAAACTACGAAAGTTAATATTTAAAATCAAAACAGATTCTTCACTTCCAAATGAACCGAAAGAATTAGAA
ACGTTATTTACGATTTATAAAGAATTTGCAAAAGAAGATGAAATGCAGTCATTACGTGAAAAATATGAGACTGGAATCGG
ATGGGGCGATGTGAAAAAAGAGTTGTTTCGCGTTGTAGACCGTGAATTAGCTGGGCCTCGTGAGAAATATGCTATGTATA
TGAATGAACCGAATTTATTATATGAAGCGTTGGAAAAAGGTGCTAAGCAGGCAAGAGAAATCGCGAAGGCAAATTTAGCA
GAAATTAAAAAAAGGATTGGGTTTGAAGGGGGACGTTAA

Upstream 100 bases:

>100_bases
GTGAGCTATAATGATAGCTAAATAAGGTGGTACCGCGGGAGTCTCTCGTCCTTTTTTTAGGATGAGGGACTCTTTTTGTT
TTGAGAAAGGAGGAGTTAGG

Downstream 100 bases:

>100_bases
GCGTTCCCTTGTTTTTTTGCAAAAAAAACGAACGAAATTTCAATTTGTTACCAATATAGAGTGAGGAGGGATAGAAATGA
TTACAACTCTCGAGTTAAAA

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MSDKIMLTGIKPTGYPHLGNYIGAIKPALQMSKKNEGKALYFIADYHALNAVHNQSQFSSYTKEVAATWLSLGLGEDVIF
YRQTEVPEILELAWILACLTPKGLMNRAHAYKAKVEQNKEAGLEVDAGVNMGLYTYPILMAADILLFQATYVPVGKDQIQ
HIEIARDIATYFNHTFGRTFTLPEYVIQEEGAILPGLDGRKMSKSYGNVIPLFAEQEKLRKLIFKIKTDSSLPNEPKELE
TLFTIYKEFAKEDEMQSLREKYETGIGWGDVKKELFRVVDRELAGPREKYAMYMNEPNLLYEALEKGAKQAREIAKANLA
EIKKRIGFEGGR

Sequences:

>Translated_332_residues
MSDKIMLTGIKPTGYPHLGNYIGAIKPALQMSKKNEGKALYFIADYHALNAVHNQSQFSSYTKEVAATWLSLGLGEDVIF
YRQTEVPEILELAWILACLTPKGLMNRAHAYKAKVEQNKEAGLEVDAGVNMGLYTYPILMAADILLFQATYVPVGKDQIQ
HIEIARDIATYFNHTFGRTFTLPEYVIQEEGAILPGLDGRKMSKSYGNVIPLFAEQEKLRKLIFKIKTDSSLPNEPKELE
TLFTIYKEFAKEDEMQSLREKYETGIGWGDVKKELFRVVDRELAGPREKYAMYMNEPNLLYEALEKGAKQAREIAKANLA
EIKKRIGFEGGR
>Mature_331_residues
SDKIMLTGIKPTGYPHLGNYIGAIKPALQMSKKNEGKALYFIADYHALNAVHNQSQFSSYTKEVAATWLSLGLGEDVIFY
RQTEVPEILELAWILACLTPKGLMNRAHAYKAKVEQNKEAGLEVDAGVNMGLYTYPILMAADILLFQATYVPVGKDQIQH
IEIARDIATYFNHTFGRTFTLPEYVIQEEGAILPGLDGRKMSKSYGNVIPLFAEQEKLRKLIFKIKTDSSLPNEPKELET
LFTIYKEFAKEDEMQSLREKYETGIGWGDVKKELFRVVDRELAGPREKYAMYMNEPNLLYEALEKGAKQAREIAKANLAE
IKKRIGFEGGR

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=337, Percent_Identity=29.9703264094956, Blast_Score=144, Evalue=9e-35,
Organism=Homo sapiens, GI41352700, Length=187, Percent_Identity=36.8983957219251, Blast_Score=139, Evalue=4e-33,
Organism=Escherichia coli, GI1789786, Length=341, Percent_Identity=31.9648093841642, Blast_Score=160, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI71982800, Length=339, Percent_Identity=31.5634218289086, Blast_Score=144, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI71982793, Length=339, Percent_Identity=31.5634218289086, Blast_Score=142, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6320474, Length=349, Percent_Identity=34.0974212034384, Blast_Score=168, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24666151, Length=335, Percent_Identity=29.8507462686567, Blast_Score=139, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37591; Mature: 37460

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS50237 HECT ; PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKIMLTGIKPTGYPHLGNYIGAIKPALQMSKKNEGKALYFIADYHALNAVHNQSQFSS
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHH
YTKEVAATWLSLGLGEDVIFYRQTEVPEILELAWILACLTPKGLMNRAHAYKAKVEQNKE
HHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHH
AGLEVDAGVNMGLYTYPILMAADILLFQATYVPVGKDQIQHIEIARDIATYFNHTFGRTF
CCCEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
TLPEYVIQEEGAILPGLDGRKMSKSYGNVIPLFAEQEKLRKLIFKIKTDSSLPNEPKELE
CCHHHHHHCCCCCCCCCCCCHHHHHHCCEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHH
TLFTIYKEFAKEDEMQSLREKYETGIGWGDVKKELFRVVDRELAGPREKYAMYMNEPNLL
HHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHEEEECCCHHH
YEALEKGAKQAREIAKANLAEIKKRIGFEGGR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SDKIMLTGIKPTGYPHLGNYIGAIKPALQMSKKNEGKALYFIADYHALNAVHNQSQFSS
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHH
YTKEVAATWLSLGLGEDVIFYRQTEVPEILELAWILACLTPKGLMNRAHAYKAKVEQNKE
HHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHH
AGLEVDAGVNMGLYTYPILMAADILLFQATYVPVGKDQIQHIEIARDIATYFNHTFGRTF
CCCEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
TLPEYVIQEEGAILPGLDGRKMSKSYGNVIPLFAEQEKLRKLIFKIKTDSSLPNEPKELE
CCHHHHHHCCCCCCCCCCCCHHHHHHCCEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHH
TLFTIYKEFAKEDEMQSLREKYETGIGWGDVKKELFRVVDRELAGPREKYAMYMNEPNLL
HHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHEEEECCCHHH
YEALEKGAKQAREIAKANLAEIKKRIGFEGGR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]