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The map label for this gene is mdtH [H]

Identifier: 52142183

GI number: 52142183

Start: 3189149

End: 3190330

Strand: Direct

Name: mdtH [H]

Synonym: BCZK3060

Alternate gene names: 52142183

Gene position: 3189149-3190330 (Clockwise)

Preceding gene: 52142186

Following gene: 52142180

Centisome position: 60.16

GC content: 32.66

Gene sequence:

>1182_bases
ATGAAAAGTTTCTCAACACCGATACGTTTCATGCTTATTTCTTCATTTTTTATGTCTTTTGGGTATTTTGCAGTATACGC
ATTTTTAGCTATTTATCTATTAACCTTTCTCCATTTTTCAGCTTTTCAAGTAGGAACAGTATTGACGGTTATGATAATTA
CATCACGAGTTATCCCTTTATTTTCAGGATTAATTGCTGACAAAATAGGCTATATCATTATGATGATAGCCGGATTATTG
TTAAGAGGAATCGGATTTATCGCTTTAGGAATATGTTCTGATTTCTATACAATTTCTATTTCTTCTGCACTTATTGGCTT
CGGAACTGCATTTTACGAACCTGCTGCTCGCGCTATATTTGGATCACAACCAGCTCATACAAGAAAAAATTTATTTACAT
ATTTAAACCTTAGCTTTAATTGTGGTGCAATAATCGGACCAATTGCAGGAGGGTTCTTACTCTTACTCGATCCAATCTAT
GCTTTCTCTCTAACAGGATCTCTTATGCTGTTATTCGCTTTTATCTTTTACTTACTTAAAAACCACTTCCAAGTCACTAC
TGAAAACACATCTATTACATTAGGAATACAGGCCATCTTACAAAACAAGTCTTTCCTTCTGTTTTCATTTATCATGATTT
TCTTCTATATTATGTTTACACAGCTTACCGTCGCACTTCCACTTCATATGAAAAACATTAGTAATAGCAATCAACTTGCT
ACATTAGTCATTACGATAAATGCAATAACAGGCGTCATATTTATGGTGTTATTTCGAAAACCCTTTCTCAAATACAACAC
CCTTTCCTTTATTAAATACGGTGTTTTATTAATGAGTATTTCCTTTTTACTCATTCCTTTATTTCAACACCCATATTGGC
TATTTATTTGTGTAATTTTCTTTACAATCGGTGAAACACTCGTATTACCTAACGTTGATATCGCCACTGCAAATTACAGT
AATGAATCATATACAGCTACTTACTTCGGATTTTATCAACTATCACTCGCATTTGGTTTTATCATCGGTAACTATATCGG
TACATGGTTTACATCAAATTTAAACGAAATGTATACACCATGGCTTATTTTTGGCGGAATAGGGCTTACTGGTTTTATTT
CACTACATATTTTGAATATAAAAAAAGTGGCCTCTAAAGAGGATAGATATATACCTATGTAA

Upstream 100 bases:

>100_bases
TCTTCTTAAAATTTACTTTTTTCTGACTTTATGTATAATTATAATATAAAATAGTTAACCATTAAATGATTTTACCGGTT
ACATAATTAGGAGGATTTCT

Downstream 100 bases:

>100_bases
TACAAGCGACCTATAACGAAAAAGATTCGACCATCATGTTTGACAGTTGAATCTTTTTATTGTTCATATTCAAGATGATT
ATGTCTTTTACAACCAAATA

Product: membrane protein; TGF-beta receptor, type I/II extracellular region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MKSFSTPIRFMLISSFFMSFGYFAVYAFLAIYLLTFLHFSAFQVGTVLTVMIITSRVIPLFSGLIADKIGYIIMMIAGLL
LRGIGFIALGICSDFYTISISSALIGFGTAFYEPAARAIFGSQPAHTRKNLFTYLNLSFNCGAIIGPIAGGFLLLLDPIY
AFSLTGSLMLLFAFIFYLLKNHFQVTTENTSITLGIQAILQNKSFLLFSFIMIFFYIMFTQLTVALPLHMKNISNSNQLA
TLVITINAITGVIFMVLFRKPFLKYNTLSFIKYGVLLMSISFLLIPLFQHPYWLFICVIFFTIGETLVLPNVDIATANYS
NESYTATYFGFYQLSLAFGFIIGNYIGTWFTSNLNEMYTPWLIFGGIGLTGFISLHILNIKKVASKEDRYIPM

Sequences:

>Translated_393_residues
MKSFSTPIRFMLISSFFMSFGYFAVYAFLAIYLLTFLHFSAFQVGTVLTVMIITSRVIPLFSGLIADKIGYIIMMIAGLL
LRGIGFIALGICSDFYTISISSALIGFGTAFYEPAARAIFGSQPAHTRKNLFTYLNLSFNCGAIIGPIAGGFLLLLDPIY
AFSLTGSLMLLFAFIFYLLKNHFQVTTENTSITLGIQAILQNKSFLLFSFIMIFFYIMFTQLTVALPLHMKNISNSNQLA
TLVITINAITGVIFMVLFRKPFLKYNTLSFIKYGVLLMSISFLLIPLFQHPYWLFICVIFFTIGETLVLPNVDIATANYS
NESYTATYFGFYQLSLAFGFIIGNYIGTWFTSNLNEMYTPWLIFGGIGLTGFISLHILNIKKVASKEDRYIPM
>Mature_393_residues
MKSFSTPIRFMLISSFFMSFGYFAVYAFLAIYLLTFLHFSAFQVGTVLTVMIITSRVIPLFSGLIADKIGYIIMMIAGLL
LRGIGFIALGICSDFYTISISSALIGFGTAFYEPAARAIFGSQPAHTRKNLFTYLNLSFNCGAIIGPIAGGFLLLLDPIY
AFSLTGSLMLLFAFIFYLLKNHFQVTTENTSITLGIQAILQNKSFLLFSFIMIFFYIMFTQLTVALPLHMKNISNSNQLA
TLVITINAITGVIFMVLFRKPFLKYNTLSFIKYGVLLMSISFLLIPLFQHPYWLFICVIFFTIGETLVLPNVDIATANYS
NESYTATYFGFYQLSLAFGFIIGNYIGTWFTSNLNEMYTPWLIFGGIGLTGFISLHILNIKKVASKEDRYIPM

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081828, Length=390, Percent_Identity=24.3589743589744, Blast_Score=119, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR022855
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44163; Mature: 44163

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSFSTPIRFMLISSFFMSFGYFAVYAFLAIYLLTFLHFSAFQVGTVLTVMIITSRVIPL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSGLIADKIGYIIMMIAGLLLRGIGFIALGICSDFYTISISSALIGFGTAFYEPAARAIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHHHHHHHHC
GSQPAHTRKNLFTYLNLSFNCGAIIGPIAGGFLLLLDPIYAFSLTGSLMLLFAFIFYLLK
CCCCCHHHHHHEEEEEECCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NHFQVTTENTSITLGIQAILQNKSFLLFSFIMIFFYIMFTQLTVALPLHMKNISNSNQLA
CCEEEEECCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
TLVITINAITGVIFMVLFRKPFLKYNTLSFIKYGVLLMSISFLLIPLFQHPYWLFICVIF
EEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
FTIGETLVLPNVDIATANYSNESYTATYFGFYQLSLAFGFIIGNYIGTWFTSNLNEMYTP
HHHCCEEEECCCEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCC
WLIFGGIGLTGFISLHILNIKKVASKEDRYIPM
HHHCCCCCHHHHHHHHEEHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKSFSTPIRFMLISSFFMSFGYFAVYAFLAIYLLTFLHFSAFQVGTVLTVMIITSRVIPL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSGLIADKIGYIIMMIAGLLLRGIGFIALGICSDFYTISISSALIGFGTAFYEPAARAIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHHHHHHHHC
GSQPAHTRKNLFTYLNLSFNCGAIIGPIAGGFLLLLDPIYAFSLTGSLMLLFAFIFYLLK
CCCCCHHHHHHEEEEEECCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NHFQVTTENTSITLGIQAILQNKSFLLFSFIMIFFYIMFTQLTVALPLHMKNISNSNQLA
CCEEEEECCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
TLVITINAITGVIFMVLFRKPFLKYNTLSFIKYGVLLMSISFLLIPLFQHPYWLFICVIF
EEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
FTIGETLVLPNVDIATANYSNESYTATYFGFYQLSLAFGFIIGNYIGTWFTSNLNEMYTP
HHHCCEEEECCCEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCC
WLIFGGIGLTGFISLHILNIKKVASKEDRYIPM
HHHCCCCCHHHHHHHHEEHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA