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The map label for this gene is gntK [H]

Identifier: 52142163

GI number: 52142163

Start: 3205442

End: 3206983

Strand: Reverse

Name: gntK [H]

Synonym: BCZK3078

Alternate gene names: 52142163

Gene position: 3206983-3205442 (Counterclockwise)

Preceding gene: 52142164

Following gene: 52142168

Centisome position: 60.5

GC content: 38.0

Gene sequence:

>1542_bases
ATGGTGAGGTCAAAATATATGATTGGTGTAGACATTGGGACAACTAGTACAAAATCAGTTCTATTTTCTACTGATGGATC
TGTTATTGCAAGTCATGGAATTGAATATCCTTTATATTCTCCTACGCCGGAAACAGCAGAACAAGACCCAGAAGAAATTT
TTCGTGCAGTAATACATACGATTAAAGAAACTGTACAGTCAAGTAGTGTACAGCCAAATGATATTCTTTGCGTCTCTTTT
AGTTCGGCAATGCATAGTATCATTGCTGTAGATGAGAAGGGAAAGCCGTTAACGAGATGTATTACTTGGGCAGATAATAG
AAGTGCAAGCTGGGCAGAGAAAATAAAGAATGATATGAATGGTCATGAAATTTATTTGCGGACTGGGACACCAATTCATC
CGATGTCACCACTTTCGAAATTAGTTTGGCTACAAAATGAGCAGGCAGAATTGTTCGCAAAAACTTATAAATTTATTTCT
ATTAAAGAGTATGTTTTTTATAAGTTATATAAGGAGTATGTAATTGATTATTCTATAGCATCAGCAACAGGGATGTTTAA
TTTGAAATCTTTGAAATGGGATGAAGAGGCTTTATATGTTGCGGGAATTACAGATGACAAACTTTCTAAACTGGTTCCAA
CAACGCACAGTTTAACAGGATTAGATGAAGAGCTTGCCAATGAGATGAATGTACTTGTTTCTACTCCATTTGTAGTAGGA
GCGAGTGACGGAGTCCTATCCAATTTAGGTGTAAATGCAATTGATCCTGGTGTTGTGGCTGTTACAATTGGTACAAGCGG
TGCGATACGTGCTGTAACAAATCGTCCTGTAACAGATCCAAAAGGTAGAATTTTTTGTTACGCCTTAACTGAAGACCATT
GGGTAATTGGCGGACCGGTTAATAACGGTGGTATGATTTTCAGATGGGCTCGTGATCAATTAGGCACTTCAGAGATTGAG
CTTGCGAAGCGTTTAGGAAAAGATCCATATGAAGTGCTTACTGAAATAGCAGCAAAAGTGAATCCGGGATCTGACGGTTT
ATTATTTCATCCGTATTTAGCAGGGGAAAGAGCTCCTTTATGGAATGCAAATGCGCGAGGATCTTTCTTTGGACTTGGAT
TGCATCATAAGAAAGAACATCTTATCCGTGCTGTTTTAGAAGGAGTAATTTATAATTTATATACCGTTCTCCTTGCTTTA
AAAGAACTCATTGGTGAACCGAAAAAAATTCAAGCGACAGGCGGTTTTGCAAGATCGGAACTTTGGAGACAGATGATGGC
GGATATTTTTCATCAAGACGTATATGTTCCCGAAAGTTTCGAAAGCTCTTGCTTAGGAGCTGCCATCCTCGGCTTATATA
GTTTAGGTGAAGTAGATACGTTGCATGTAGTTTCTGAAATGGTAGGTGCGAATTTCCACCATGAACCAAACATGGAAAGT
GTGGAAAAATATAAAGATTTAACACCAATCTATATTCGTCTGTCCCGTCAATTGGAAGAAGAATATGAAAGTATAGCAGC
GTATCAAAAAAAGTGGGTTTAA

Upstream 100 bases:

>100_bases
TTTATCGCTTTTGGAGGAGTTTTACTACTCGATATGTTTGTTTAAAATAAGGATGTTTTTATGGTGGGATACTGTAGTAA
TTTTTTGTTAGGAGGAAGAA

Downstream 100 bases:

>100_bases
AGGCTATTTTGCAAGAAAATATGGTAACGTATAAAGAGGTACTCCAATTCTTTTAGGATACTCTTTCAACATAAAATATG
TTAAGAAGTATGATGAACGA

Product: gluconate kinase (2-dehydro-3-deoxygluconokinase)

Products: NA

Alternate protein names: Gluconate kinase [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MVRSKYMIGVDIGTTSTKSVLFSTDGSVIASHGIEYPLYSPTPETAEQDPEEIFRAVIHTIKETVQSSSVQPNDILCVSF
SSAMHSIIAVDEKGKPLTRCITWADNRSASWAEKIKNDMNGHEIYLRTGTPIHPMSPLSKLVWLQNEQAELFAKTYKFIS
IKEYVFYKLYKEYVIDYSIASATGMFNLKSLKWDEEALYVAGITDDKLSKLVPTTHSLTGLDEELANEMNVLVSTPFVVG
ASDGVLSNLGVNAIDPGVVAVTIGTSGAIRAVTNRPVTDPKGRIFCYALTEDHWVIGGPVNNGGMIFRWARDQLGTSEIE
LAKRLGKDPYEVLTEIAAKVNPGSDGLLFHPYLAGERAPLWNANARGSFFGLGLHHKKEHLIRAVLEGVIYNLYTVLLAL
KELIGEPKKIQATGGFARSELWRQMMADIFHQDVYVPESFESSCLGAAILGLYSLGEVDTLHVVSEMVGANFHHEPNMES
VEKYKDLTPIYIRLSRQLEEEYESIAAYQKKWV

Sequences:

>Translated_513_residues
MVRSKYMIGVDIGTTSTKSVLFSTDGSVIASHGIEYPLYSPTPETAEQDPEEIFRAVIHTIKETVQSSSVQPNDILCVSF
SSAMHSIIAVDEKGKPLTRCITWADNRSASWAEKIKNDMNGHEIYLRTGTPIHPMSPLSKLVWLQNEQAELFAKTYKFIS
IKEYVFYKLYKEYVIDYSIASATGMFNLKSLKWDEEALYVAGITDDKLSKLVPTTHSLTGLDEELANEMNVLVSTPFVVG
ASDGVLSNLGVNAIDPGVVAVTIGTSGAIRAVTNRPVTDPKGRIFCYALTEDHWVIGGPVNNGGMIFRWARDQLGTSEIE
LAKRLGKDPYEVLTEIAAKVNPGSDGLLFHPYLAGERAPLWNANARGSFFGLGLHHKKEHLIRAVLEGVIYNLYTVLLAL
KELIGEPKKIQATGGFARSELWRQMMADIFHQDVYVPESFESSCLGAAILGLYSLGEVDTLHVVSEMVGANFHHEPNMES
VEKYKDLTPIYIRLSRQLEEEYESIAAYQKKWV
>Mature_513_residues
MVRSKYMIGVDIGTTSTKSVLFSTDGSVIASHGIEYPLYSPTPETAEQDPEEIFRAVIHTIKETVQSSSVQPNDILCVSF
SSAMHSIIAVDEKGKPLTRCITWADNRSASWAEKIKNDMNGHEIYLRTGTPIHPMSPLSKLVWLQNEQAELFAKTYKFIS
IKEYVFYKLYKEYVIDYSIASATGMFNLKSLKWDEEALYVAGITDDKLSKLVPTTHSLTGLDEELANEMNVLVSTPFVVG
ASDGVLSNLGVNAIDPGVVAVTIGTSGAIRAVTNRPVTDPKGRIFCYALTEDHWVIGGPVNNGGMIFRWARDQLGTSEIE
LAKRLGKDPYEVLTEIAAKVNPGSDGLLFHPYLAGERAPLWNANARGSFFGLGLHHKKEHLIRAVLEGVIYNLYTVLLAL
KELIGEPKKIQATGGFARSELWRQMMADIFHQDVYVPESFESSCLGAAILGLYSLGEVDTLHVVSEMVGANFHHEPNMES
VEKYKDLTPIYIRLSRQLEEEYESIAAYQKKWV

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI88196792, Length=483, Percent_Identity=26.0869565217391, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI189409120, Length=462, Percent_Identity=26.8398268398268, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI42794763, Length=463, Percent_Identity=25.9179265658747, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI4504007, Length=463, Percent_Identity=26.7818574514039, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI41393575, Length=453, Percent_Identity=26.2693156732892, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI164663828, Length=547, Percent_Identity=23.0347349177331, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI1789987, Length=494, Percent_Identity=27.3279352226721, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI1787789, Length=499, Percent_Identity=28.6573146292585, Blast_Score=161, Evalue=7e-41,
Organism=Escherichia coli, GI1790361, Length=501, Percent_Identity=26.5469061876248, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1790005, Length=494, Percent_Identity=22.8744939271255, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1789168, Length=491, Percent_Identity=21.1812627291242, Blast_Score=102, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17535599, Length=459, Percent_Identity=24.8366013071895, Blast_Score=121, Evalue=8e-28,
Organism=Saccharomyces cerevisiae, GI6321755, Length=536, Percent_Identity=25.3731343283582, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24655555, Length=476, Percent_Identity=24.5798319327731, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24655560, Length=476, Percent_Identity=24.5798319327731, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24655570, Length=476, Percent_Identity=24.5798319327731, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24655574, Length=476, Percent_Identity=24.5798319327731, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24655565, Length=476, Percent_Identity=24.5798319327731, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24656367, Length=551, Percent_Identity=22.5045372050817, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI21357867, Length=564, Percent_Identity=21.9858156028369, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI17864214, Length=475, Percent_Identity=24.2105263157895, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24654573, Length=423, Percent_Identity=23.6406619385343, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24657106, Length=562, Percent_Identity=23.3096085409253, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24657102, Length=562, Percent_Identity=23.3096085409253, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24656372, Length=366, Percent_Identity=21.8579234972678, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006002 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 56980; Mature: 56980

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRSKYMIGVDIGTTSTKSVLFSTDGSVIASHGIEYPLYSPTPETAEQDPEEIFRAVIHT
CCCCEEEEEEEECCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
IKETVQSSSVQPNDILCVSFSSAMHSIIAVDEKGKPLTRCITWADNRSASWAEKIKNDMN
HHHHHHHCCCCCCCEEEEEEHHHHHHEEEECCCCCCHHHEEEECCCCCHHHHHHHHCCCC
GHEIYLRTGTPIHPMSPLSKLVWLQNEQAELFAKTYKFISIKEYVFYKLYKEYVIDYSIA
CCEEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SATGMFNLKSLKWDEEALYVAGITDDKLSKLVPTTHSLTGLDEELANEMNVLVSTPFVVG
HHCCCEEECCCCCCCCEEEEEECCHHHHHHHCCCCCHHCCCHHHHHHHHHEEEECCEEEE
ASDGVLSNLGVNAIDPGVVAVTIGTSGAIRAVTNRPVTDPKGRIFCYALTEDHWVIGGPV
CCCCHHHHCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCEEEEEECCCCEEEECEE
NNGGMIFRWARDQLGTSEIELAKRLGKDPYEVLTEIAAKVNPGSDGLLFHPYLAGERAPL
CCCCEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCC
WNANARGSFFGLGLHHKKEHLIRAVLEGVIYNLYTVLLALKELIGEPKKIQATGGFARSE
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHH
LWRQMMADIFHQDVYVPESFESSCLGAAILGLYSLGEVDTLHVVSEMVGANFHHEPNMES
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHH
VEKYKDLTPIYIRLSRQLEEEYESIAAYQKKWV
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVRSKYMIGVDIGTTSTKSVLFSTDGSVIASHGIEYPLYSPTPETAEQDPEEIFRAVIHT
CCCCEEEEEEEECCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
IKETVQSSSVQPNDILCVSFSSAMHSIIAVDEKGKPLTRCITWADNRSASWAEKIKNDMN
HHHHHHHCCCCCCCEEEEEEHHHHHHEEEECCCCCCHHHEEEECCCCCHHHHHHHHCCCC
GHEIYLRTGTPIHPMSPLSKLVWLQNEQAELFAKTYKFISIKEYVFYKLYKEYVIDYSIA
CCEEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SATGMFNLKSLKWDEEALYVAGITDDKLSKLVPTTHSLTGLDEELANEMNVLVSTPFVVG
HHCCCEEECCCCCCCCEEEEEECCHHHHHHHCCCCCHHCCCHHHHHHHHHEEEECCEEEE
ASDGVLSNLGVNAIDPGVVAVTIGTSGAIRAVTNRPVTDPKGRIFCYALTEDHWVIGGPV
CCCCHHHHCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCEEEEEECCCCEEEECEE
NNGGMIFRWARDQLGTSEIELAKRLGKDPYEVLTEIAAKVNPGSDGLLFHPYLAGERAPL
CCCCEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCC
WNANARGSFFGLGLHHKKEHLIRAVLEGVIYNLYTVLLALKELIGEPKKIQATGGFARSE
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHH
LWRQMMADIFHQDVYVPESFESSCLGAAILGLYSLGEVDTLHVVSEMVGANFHHEPNMES
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHH
VEKYKDLTPIYIRLSRQLEEEYESIAAYQKKWV
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3020045; 7584049; 9384377 [H]