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The map label for this gene is bla

Identifier: 52142087

GI number: 52142087

Start: 3285480

End: 3285995

Strand: Reverse

Name: bla

Synonym: BCZK3155

Alternate gene names: NA

Gene position: 3285995-3285480 (Counterclockwise)

Preceding gene: 52142086

Following gene: 161763545

Centisome position: 61.99

GC content: 36.05

Gene sequence:

>516_bases
ATGGCAGAAAAGAAATTTAAGAAGAGTGTAACGGATGTTATTATTACACATGCACACGCTGATCGGATTGGCGGAATAAA
AACGTTGAAAGAAAGAGGCATTAAAGCGCATAGTACAACGTTAACTGCGGAACTAGCAAAGAAAAATGGATATGAAGAAC
CACTTGGAGACTTACAAGCAATTACGAAATTGAAGTTTGGAAATATGAAAGTAGAAACGTTTTACCCAGGGAAAGGACAT
ACAGAAGATAATATCGTCGTATGGTTACCACAATACAACATGTTAGTTGGAGGCTGTTTAGTGAAGTATGCGTCCGCGAA
AGATTTAGGAAATGTTACTGATGCTTATGTAAATGAATGGTCTACATCGATTGAGAATGTGCTGAAGCGATATGAAAATA
TAAATTTTGTAGTACCTGGTCATGGAGAAGTAGGGGATAAAGGATTACTTTTACATACATTGGATTTGTTAAAAGAAAAA
AGCGAGGAGAAACAATTTCTCCTCGCTTTTTTCTAA

Upstream 100 bases:

>100_bases
CTGTACAAGCAGAACGAACGGTTTAATCCTTAATACTTCTAAAGGATTAGTACTTGTCGATTCTTCTTGGGATGATAAGT
TAACGAAGGAATTAATAGAG

Downstream 100 bases:

>100_bases
CTATATTTAAATGCGAAGCTATGCATACTTTACTGAGATTTTAATTCCAAGTATACAAATACTAGTACTGTCATAATTGC
AATAACAACGTAAGTAGCAT

Product: beta-lactamase II

Products: NA

Alternate protein names: Beta-lactamase II; Cephalosporinase; Penicillinase [H]

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MAEKKFKKSVTDVIITHAHADRIGGIKTLKERGIKAHSTTLTAELAKKNGYEEPLGDLQAITKLKFGNMKVETFYPGKGH
TEDNIVVWLPQYNMLVGGCLVKYASAKDLGNVTDAYVNEWSTSIENVLKRYENINFVVPGHGEVGDKGLLLHTLDLLKEK
SEEKQFLLAFF

Sequences:

>Translated_171_residues
MAEKKFKKSVTDVIITHAHADRIGGIKTLKERGIKAHSTTLTAELAKKNGYEEPLGDLQAITKLKFGNMKVETFYPGKGH
TEDNIVVWLPQYNMLVGGCLVKYASAKDLGNVTDAYVNEWSTSIENVLKRYENINFVVPGHGEVGDKGLLLHTLDLLKEK
SEEKQFLLAFF
>Mature_170_residues
AEKKFKKSVTDVIITHAHADRIGGIKTLKERGIKAHSTTLTAELAKKNGYEEPLGDLQAITKLKFGNMKVETFYPGKGHT
EDNIVVWLPQYNMLVGGCLVKYASAKDLGNVTDAYVNEWSTSIENVLKRYENINFVVPGHGEVGDKGLLLHTLDLLKEKS
EEKQFLLAFF

Specific function: Can hydrolyze carbapenem compounds [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001018
- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 19110; Mature: 18979

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS00743 BETA_LACTAMASE_B_1 ; PS00744 BETA_LACTAMASE_B_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKKFKKSVTDVIITHAHADRIGGIKTLKERGIKAHSTTLTAELAKKNGYEEPLGDLQA
CCHHHHHHHHHHHHHHHCCHHHHCCHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHH
ITKLKFGNMKVETFYPGKGHTEDNIVVWLPQYNMLVGGCLVKYASAKDLGNVTDAYVNEW
HHHHHCCCEEEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
STSIENVLKRYENINFVVPGHGEVGDKGLLLHTLDLLKEKSEEKQFLLAFF
HHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCCHHEEEEEC
>Mature Secondary Structure 
AEKKFKKSVTDVIITHAHADRIGGIKTLKERGIKAHSTTLTAELAKKNGYEEPLGDLQA
CHHHHHHHHHHHHHHHCCHHHHCCHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHH
ITKLKFGNMKVETFYPGKGHTEDNIVVWLPQYNMLVGGCLVKYASAKDLGNVTDAYVNEW
HHHHHCCCEEEEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
STSIENVLKRYENINFVVPGHGEVGDKGLLLHTLDLLKEKSEEKQFLLAFF
HHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCCHHEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3131315; 2501295; 1904717 [H]