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The map label for this gene is ag45 [H]

Identifier: 52142059

GI number: 52142059

Start: 3308027

End: 3309352

Strand: Direct

Name: ag45 [H]

Synonym: BCZK3185

Alternate gene names: 52142059

Gene position: 3308027-3309352 (Clockwise)

Preceding gene: 52142064

Following gene: 52142051

Centisome position: 62.4

GC content: 37.03

Gene sequence:

>1326_bases
TTGGAACAATCAGCACATGAAGTAGCAAATTGGCAATATTATTTTGCAATTGCCGTATTTTTAGTCACGTACGGATTTAT
TATTTCTGAGAAATTGAATCGTGCTGTAATTGCACTATTCGGTGCTGCTATTATGATTATTTTTGGAATTGTAGATTTAC
ACGCTGCTTTCACATCACATATTCAATGGGAAACGATCACCCTCTTAATTGGGATGATGATTCTCGTACATATTACAAGT
CAATCAGGCGTATTTGAATTTGTGGCTATTAAAGCAGCTAAGGCAGCTGGCGGCAAACCAATCCGCATTTTACTATTACT
ATCCCTATTAACCGCTGTCGGTTCTGCATTTTTGGACAACGTAACGACCGTTTTATTAATCGTTCCTGTTACATTATCCA
TTACACGTATTTTAAAAGTTAATCCTATTCCTTATTTACTTTCAGAAGTACTATTTTCAAATATAGGCGGAACAGCAACA
TTAATCGGTGACCCACCGAACATTATGATTGGATCAGCAAATAAGCATTTAGACTTTAATGCCTTTTTACTAAACTTAGC
TCCAATTGTAATTATTATTTCTATCGTTACACTTGGCATTATTTACTTCCTGTATCGCAATAAACTAAAAACAACAACTG
AACAAATTAAAATATTAATGGAATTAAACGAAAAAGATTATATTAAAGATCACAGCCTCCTTTTAAAATCCATTTCGATT
TTAGGACTAACTATTTTAGGCTTTATACTTCATTCGATTATTCACGTAGACGCTGCCGTTATCGCGATGACAGGCGCTAC
ACTTCTTATGCTAATTGGAGTAAAAGACCATGATATTGAAGATGTATTTGCCCACGTTGAATGGGTAACCATCTTCTTCT
TCGCCGGACTATTCGTTCTTGTTGGCGGTTTAATTGATATCGGGCTTATTTCTTCACTTGCAAAAGAAGTAATCGACGTA
ACAAACGGGGATATCGGTTTCGCTGCGATACTTATCTTATGGGTATCCGGCATCGCATCTGCAACCATCGACAATATCCC
ATTTGTCGCAACGATGATCCCGCTTATTCAAGATTTAGCTACAGGACTCGGACTATCTGTTGATTCCCCGCAAATCGAAG
TACTATGGTGGGCGTTATCACTTGGAGCTTGCTTAGGAGGAAACGGAACATTAATCGGAGCATCCGCAAACGTAGTCGTT
GCTGGTATTGCAAAACGTGAAGGGCATGCTTTCTCTTATATGGACTTCTTAAAAATTGGTTTACCGTTAACAATTATTGC
GCTATTGTTATCACACGCTTACATATATTTACGTTATTTAATGTAA

Upstream 100 bases:

>100_bases
TTCTTTCTTTTTTGAATTTGCTACAATATATTTTATCCCGTATTTATACAGCGGGATACATTTCAACAATTGAATACATA
CTTTAAAGAAGGTGACATGA

Downstream 100 bases:

>100_bases
AAGTTATATTGCATGAAATTATATCGTCAAATACAAAAGGTTTGCAGCACTATGCTGCAAACCTTTTTTCATCACCAAAA
TATACCGATAATTGCTAATC

Product: arsenical pump family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MEQSAHEVANWQYYFAIAVFLVTYGFIISEKLNRAVIALFGAAIMIIFGIVDLHAAFTSHIQWETITLLIGMMILVHITS
QSGVFEFVAIKAAKAAGGKPIRILLLLSLLTAVGSAFLDNVTTVLLIVPVTLSITRILKVNPIPYLLSEVLFSNIGGTAT
LIGDPPNIMIGSANKHLDFNAFLLNLAPIVIIISIVTLGIIYFLYRNKLKTTTEQIKILMELNEKDYIKDHSLLLKSISI
LGLTILGFILHSIIHVDAAVIAMTGATLLMLIGVKDHDIEDVFAHVEWVTIFFFAGLFVLVGGLIDIGLISSLAKEVIDV
TNGDIGFAAILILWVSGIASATIDNIPFVATMIPLIQDLATGLGLSVDSPQIEVLWWALSLGACLGGNGTLIGASANVVV
AGIAKREGHAFSYMDFLKIGLPLTIIALLLSHAYIYLRYLM

Sequences:

>Translated_441_residues
MEQSAHEVANWQYYFAIAVFLVTYGFIISEKLNRAVIALFGAAIMIIFGIVDLHAAFTSHIQWETITLLIGMMILVHITS
QSGVFEFVAIKAAKAAGGKPIRILLLLSLLTAVGSAFLDNVTTVLLIVPVTLSITRILKVNPIPYLLSEVLFSNIGGTAT
LIGDPPNIMIGSANKHLDFNAFLLNLAPIVIIISIVTLGIIYFLYRNKLKTTTEQIKILMELNEKDYIKDHSLLLKSISI
LGLTILGFILHSIIHVDAAVIAMTGATLLMLIGVKDHDIEDVFAHVEWVTIFFFAGLFVLVGGLIDIGLISSLAKEVIDV
TNGDIGFAAILILWVSGIASATIDNIPFVATMIPLIQDLATGLGLSVDSPQIEVLWWALSLGACLGGNGTLIGASANVVV
AGIAKREGHAFSYMDFLKIGLPLTIIALLLSHAYIYLRYLM
>Mature_441_residues
MEQSAHEVANWQYYFAIAVFLVTYGFIISEKLNRAVIALFGAAIMIIFGIVDLHAAFTSHIQWETITLLIGMMILVHITS
QSGVFEFVAIKAAKAAGGKPIRILLLLSLLTAVGSAFLDNVTTVLLIVPVTLSITRILKVNPIPYLLSEVLFSNIGGTAT
LIGDPPNIMIGSANKHLDFNAFLLNLAPIVIIISIVTLGIIYFLYRNKLKTTTEQIKILMELNEKDYIKDHSLLLKSISI
LGLTILGFILHSIIHVDAAVIAMTGATLLMLIGVKDHDIEDVFAHVEWVTIFFFAGLFVLVGGLIDIGLISSLAKEVIDV
TNGDIGFAAILILWVSGIASATIDNIPFVATMIPLIQDLATGLGLSVDSPQIEVLWWALSLGACLGGNGTLIGASANVVV
AGIAKREGHAFSYMDFLKIGLPLTIIALLLSHAYIYLRYLM

Specific function: Unknown

COG id: COG1055

COG function: function code P; Na+/H+ antiporter NhaD and related arsenite permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitM (TC 2.A.11) transporter family [H]

Homologues:

Organism=Homo sapiens, GI157266326, Length=503, Percent_Identity=34.9900596421471, Blast_Score=248, Evalue=8e-66,
Organism=Drosophila melanogaster, GI24581759, Length=496, Percent_Identity=32.6612903225806, Blast_Score=242, Evalue=4e-64,
Organism=Drosophila melanogaster, GI28574683, Length=497, Percent_Identity=32.9979879275654, Blast_Score=242, Evalue=4e-64,
Organism=Drosophila melanogaster, GI28574681, Length=497, Percent_Identity=32.9979879275654, Blast_Score=242, Evalue=4e-64,
Organism=Drosophila melanogaster, GI28574685, Length=497, Percent_Identity=32.9979879275654, Blast_Score=242, Evalue=4e-64,
Organism=Drosophila melanogaster, GI28574678, Length=497, Percent_Identity=32.9979879275654, Blast_Score=242, Evalue=4e-64,
Organism=Drosophila melanogaster, GI19920704, Length=497, Percent_Identity=32.9979879275654, Blast_Score=242, Evalue=4e-64,
Organism=Drosophila melanogaster, GI221472711, Length=497, Percent_Identity=29.7786720321932, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI24581764, Length=497, Percent_Identity=29.7786720321932, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI45550608, Length=471, Percent_Identity=32.484076433121, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI62484377, Length=454, Percent_Identity=25.9911894273128, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI85724998, Length=454, Percent_Identity=25.9911894273128, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24656008, Length=462, Percent_Identity=26.1904761904762, Blast_Score=119, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000802
- InterPro:   IPR004680 [H]

Pfam domain/function: PF03600 CitMHS [H]

EC number: NA

Molecular weight: Translated: 47681; Mature: 47681

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQSAHEVANWQYYFAIAVFLVTYGFIISEKLNRAVIALFGAAIMIIFGIVDLHAAFTSH
CCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IQWETITLLIGMMILVHITSQSGVFEFVAIKAAKAAGGKPIRILLLLSLLTAVGSAFLDN
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
VTTVLLIVPVTLSITRILKVNPIPYLLSEVLFSNIGGTATLIGDPPNIMIGSANKHLDFN
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCCCHH
AFLLNLAPIVIIISIVTLGIIYFLYRNKLKTTTEQIKILMELNEKDYIKDHSLLLKSISI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LGLTILGFILHSIIHVDAAVIAMTGATLLMLIGVKDHDIEDVFAHVEWVTIFFFAGLFVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
VGGLIDIGLISSLAKEVIDVTNGDIGFAAILILWVSGIASATIDNIPFVATMIPLIQDLA
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
TGLGLSVDSPQIEVLWWALSLGACLGGNGTLIGASANVVVAGIAKREGHAFSYMDFLKIG
HHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEECCCCCCHHHHHHHHHC
LPLTIIALLLSHAYIYLRYLM
CHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEQSAHEVANWQYYFAIAVFLVTYGFIISEKLNRAVIALFGAAIMIIFGIVDLHAAFTSH
CCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IQWETITLLIGMMILVHITSQSGVFEFVAIKAAKAAGGKPIRILLLLSLLTAVGSAFLDN
CCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
VTTVLLIVPVTLSITRILKVNPIPYLLSEVLFSNIGGTATLIGDPPNIMIGSANKHLDFN
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCCCCCHH
AFLLNLAPIVIIISIVTLGIIYFLYRNKLKTTTEQIKILMELNEKDYIKDHSLLLKSISI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LGLTILGFILHSIIHVDAAVIAMTGATLLMLIGVKDHDIEDVFAHVEWVTIFFFAGLFVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
VGGLIDIGLISSLAKEVIDVTNGDIGFAAILILWVSGIASATIDNIPFVATMIPLIQDLA
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
TGLGLSVDSPQIEVLWWALSLGACLGGNGTLIGASANVVVAGIAKREGHAFSYMDFLKIG
HHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEECCCCCCHHHHHHHHHC
LPLTIIALLLSHAYIYLRYLM
CHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]