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The map label for this gene is nhoA [H]

Identifier: 52142037

GI number: 52142037

Start: 3328319

End: 3329110

Strand: Direct

Name: nhoA [H]

Synonym: BCZK3206

Alternate gene names: 52142037

Gene position: 3328319-3329110 (Clockwise)

Preceding gene: 52142043

Following gene: 52142036

Centisome position: 62.79

GC content: 32.7

Gene sequence:

>792_bases
ATGACCGACTTTCAAAAACAATTTTTTGCAAGATTACATATAGAAGAAAAACAAAAAGTTTCATTTGAAGATTTACCTAA
CATTATGTACGCAATGGCACAAACTGTCCCATTTGAAAACTTAAATGTTCTCGAAAAGAATTTTAAGGAAATATCAAAAG
AAAATCTAAAAGAAAAAATTTTAGTAAACAATCGTGGTGGTCTTTGTTATGAACTCAATCCTACTATGTATTATTTCCTT
AAAGATGCTGGATTCGATGTTTATCTCGTTTCAGGAACAGTGTATAACGCTGCAAATTCCATATGGGCCGTTGATTCCGG
ACATATCGCAACCGTTTTAAAACATCATAATGAGCTTTATTTAATTGAAGTTGGATTCGGATCGTACTTACCTCTTGCAC
CTGTTCCTTTCTCAGGTGAAGTCATTCATTCCGTTACAGGAGATTATCGTATTCGTAAAGAAATAACCGAAAAAGGAAAC
TATATTTTAGAGATGCGTAAAAACGATGAGTTTTTGGATCAATCTTCTACTGATGATTGGACGTTAGGCTATGCATTTTA
TATAGAAGAAGTCGATGAAGAAAAAGCAAATGCAGCACAAAAAATTATTGTTGAACATGAGGGCTCACCATTTAACAAAG
TACCTCTTATTGTAAAACTAACTGAAGATGGGCATGCATCTTTAACGAAGGATAGTCTGACCGTAACAAAAAACGGTGCA
AAAACAAAAGAAACCGTTACAGATGTGCAATATAAAAATCTTTTACATTCAAAATTTGGAATTACATTATAA

Upstream 100 bases:

>100_bases
GAAGTAAAGGTGTCATACTTTAGTCGTACGCACATATGCAGATGTTTTCTTCTTAATGATTCAATATAATTTATTTAGAA
CAAATTTTGGAGGGATTTCT

Downstream 100 bases:

>100_bases
TTTGTTTAGCCTTGCCTTTTAGCAAGGCTTTTTAATTTTCAGCAGGGATTTTTTGCAATTTGTTGTATTTCATAGTTATA
TAGAAATATAACTACATATT

Product: N-hydroxyarylamine O-acetyltransferase (arylamine N-acetyltransferase)

Products: CoA; an n-acetoxyarylamine [C]

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MTDFQKQFFARLHIEEKQKVSFEDLPNIMYAMAQTVPFENLNVLEKNFKEISKENLKEKILVNNRGGLCYELNPTMYYFL
KDAGFDVYLVSGTVYNAANSIWAVDSGHIATVLKHHNELYLIEVGFGSYLPLAPVPFSGEVIHSVTGDYRIRKEITEKGN
YILEMRKNDEFLDQSSTDDWTLGYAFYIEEVDEEKANAAQKIIVEHEGSPFNKVPLIVKLTEDGHASLTKDSLTVTKNGA
KTKETVTDVQYKNLLHSKFGITL

Sequences:

>Translated_263_residues
MTDFQKQFFARLHIEEKQKVSFEDLPNIMYAMAQTVPFENLNVLEKNFKEISKENLKEKILVNNRGGLCYELNPTMYYFL
KDAGFDVYLVSGTVYNAANSIWAVDSGHIATVLKHHNELYLIEVGFGSYLPLAPVPFSGEVIHSVTGDYRIRKEITEKGN
YILEMRKNDEFLDQSSTDDWTLGYAFYIEEVDEEKANAAQKIIVEHEGSPFNKVPLIVKLTEDGHASLTKDSLTVTKNGA
KTKETVTDVQYKNLLHSKFGITL
>Mature_262_residues
TDFQKQFFARLHIEEKQKVSFEDLPNIMYAMAQTVPFENLNVLEKNFKEISKENLKEKILVNNRGGLCYELNPTMYYFLK
DAGFDVYLVSGTVYNAANSIWAVDSGHIATVLKHHNELYLIEVGFGSYLPLAPVPFSGEVIHSVTGDYRIRKEITEKGNY
ILEMRKNDEFLDQSSTDDWTLGYAFYIEEVDEEKANAAQKIIVEHEGSPFNKVPLIVKLTEDGHASLTKDSLTVTKNGAK
TKETVTDVQYKNLLHSKFGITL

Specific function: Unknown

COG id: COG2162

COG function: function code Q; Arylamine N-acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arylamine N-acetyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI237649128, Length=249, Percent_Identity=23.6947791164659, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI237649126, Length=249, Percent_Identity=23.6947791164659, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI237649124, Length=249, Percent_Identity=23.6947791164659, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI237649122, Length=249, Percent_Identity=23.6947791164659, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI237649119, Length=249, Percent_Identity=23.6947791164659, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI42741671, Length=249, Percent_Identity=23.6947791164659, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI237649009, Length=249, Percent_Identity=23.6947791164659, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI237649132, Length=249, Percent_Identity=23.6947791164659, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI237649130, Length=249, Percent_Identity=23.6947791164659, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1787736, Length=264, Percent_Identity=23.8636363636364, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001447 [H]

Pfam domain/function: PF00797 Acetyltransf_2 [H]

EC number: 2.3.1.118 [C]

Molecular weight: Translated: 29963; Mature: 29832

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDFQKQFFARLHIEEKQKVSFEDLPNIMYAMAQTVPFENLNVLEKNFKEISKENLKEKI
CCCHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHEE
LVNNRGGLCYELNPTMYYFLKDAGFDVYLVSGTVYNAANSIWAVDSGHIATVLKHHNELY
EEECCCCEEEEECCEEEEEEECCCCEEEEEECEEECCCCCEEEECCCCEEEEEECCCEEE
LIEVGFGSYLPLAPVPFSGEVIHSVTGDYRIRKEITEKGNYILEMRKNDEFLDQSSTDDW
EEEECCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCCCE
TLGYAFYIEEVDEEKANAAQKIIVEHEGSPFNKVPLIVKLTEDGHASLTKDSLTVTKNGA
EEEEEEEEEHHHHHHHHHHHEEEEEECCCCCCCCCEEEEECCCCCCEEECCCEEEECCCC
KTKETVTDVQYKNLLHSKFGITL
CCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TDFQKQFFARLHIEEKQKVSFEDLPNIMYAMAQTVPFENLNVLEKNFKEISKENLKEKI
CCHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHEE
LVNNRGGLCYELNPTMYYFLKDAGFDVYLVSGTVYNAANSIWAVDSGHIATVLKHHNELY
EEECCCCEEEEECCEEEEEEECCCCEEEEEECEEECCCCCEEEECCCCEEEEEECCCEEE
LIEVGFGSYLPLAPVPFSGEVIHSVTGDYRIRKEITEKGNYILEMRKNDEFLDQSSTDDW
EEEECCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCCCE
TLGYAFYIEEVDEEKANAAQKIIVEHEGSPFNKVPLIVKLTEDGHASLTKDSLTVTKNGA
EEEEEEEEEHHHHHHHHHHHEEEEEECCCCCCCCCEEEEECCCCCCEEECCCEEEECCCC
KTKETVTDVQYKNLLHSKFGITL
CCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; an n-hydroxyarylamine [C]

Specific reaction: Acetyl-CoA + an n-hydroxyarylamine = CoA + an n-acetoxyarylamine [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]