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The map label for this gene is schC [H]

Identifier: 52142025

GI number: 52142025

Start: 3339755

End: 3341392

Strand: Reverse

Name: schC [H]

Synonym: BCZK3219

Alternate gene names: 52142025

Gene position: 3341392-3339755 (Counterclockwise)

Preceding gene: 52142018

Following gene: 52142024

Centisome position: 63.03

GC content: 36.63

Gene sequence:

>1638_bases
GTGGAGGATAAATATATGGAATCGAATGATGTACCAGTTTTAATTGTTGGAGGTGGATTATCAGGATTAGCATCTGCGTT
ATTTCTTGCAAAACATAATATTGAGTACTTACTTATTGAAAGGCATCCGTCTACTGCAATTCATCCAAAAGCAGGTGGAA
TCACTTTTCGTACGATGGAGTTATTTCGAGAATTGGGTTTAGAACAAAGAATTAGATCAGCGGGTAAAACATTAGAAAAT
TGCCGAGGAAGAATAGCTGTTCATACAATAGCTGAGGCGAATCAGGAAGAATTCGCACAATTGAGGGTGACTCAGTATGA
AAACGATGAAAAATTACTTCAAAAAGTAAAAGAGATTAGTCCATCAAAACAAACTGCGTGTTATCAAATAATTTTAGAAG
AGATGATGTTACAGGAAGCGAAAACGCTAGGCGGGCAACTATCTTTTTATCATGAATTAGTTTCATTTGAACAAAATGAA
AACGGGGTAAAAGCAACGATTCGAAATCGTGAAACAAAAAAAGAAGGTGTCATACATTGTGACTATGTAATTGCAGCAGA
TGGGGCAAAAAGTAAAATACGTGAGCAGCTAGGGATAAGTACGGAGGGACGAGGTACAATCGGTGGCTATTATATGAATA
TTTATTTTGAAGCGGATTTAAGTGAATTTATACAAGGAGATGCATTCGGTTTTTCTATGGTACTCCATCCAGAAGTTCTT
GGTGCGCTTATTCCAGTTGATAACGAAAGAAGATGGATTTACCATGTATCCTACGATCCATTAAAAGGAGAGCAACCAGA
AGATTTCACTATAGAACGTTGTAAACAAATTATTCAAACCGCAATAGGAAGTACAAATGTTGAGTCAGAAATAGTAAGTG
TTTTACCGTGGGAAGCGACTGAAAGTACTGCTACAAAATTTCAAGATAATCGCATTTTTTTAGTTGGTGATTCTGCACAT
ATTATGCCGCCAACAGGAGGGCTTGGTTCCAATACAGGAATACAAGATGCGCACAATCTAGCTTGGAAATTAGCGGCTGT
TATAAAAGGAAAAGCAAACCCGAAATTGTTAGAAACATATCATAAAGAGAGATATCCTGTTGCAAAATTAACGACAGATT
ATGCGAGTAGTTTACTGTTTCGTGCTGCGAATAGAGAGGAAGGCAGTTTGAATAAGATGGATGGTTTAGCTGTAACTGCT
GGGTATCATTATAGTTCAGATGCAATAATAGATGATGACTCAGTCACTCCACATAGAATGGATATAGTACAGTTGAACGG
AAGACCTGGAACGCGAGCACCACATTTTATTGGAATGTATGAGGAGAAAGAAGTCTCTGTCCTTGATTTATTAGGTAACG
ATTTTGTTTTGCTTACTGGAGCAGAAAATGATTCTTGGGCTGAATCAGCACATACTGTTTCAGCTAAATTAGGAGTAAAT
ATAAAAGTATATCGCGTTGGTTTAAGTGGAGATTTTATTGCTCAAGAAAATGTTTTTAGCGAATTATATGGTTTAAGTGA
TGGAGGAGCTGTATTAATTAGACCAGATGCTTTTATAGGATGGCGTTCGGAAAAAGAGGTAGTAAATCTAGATGTAGTGC
TTGAAGAGGTAATGGGTAATTTATTATGTGATTTTTAA

Upstream 100 bases:

>100_bases
GGGGCGTAATCTATCTATATGATAATTTAAAATGAAATATAAGTCTATATCTTTGTTGTTTTTTTGATTATATTTATGTC
ACTGAGCTCAGAACAATGAT

Downstream 100 bases:

>100_bases
GTAACTAAGGAAGTATTGTCTTTTATAGAACGATACTTCTATTTTTTTAGCTTAAAAAATAAAGATTGTGTAGTGAAGAG
ACATTATTATTATAAAAATA

Product: PheA/TfdB family FAD-binding monooxygenase

Products: H2O; 3-(2,3-dihydroxyphenyl)propionate; NAD [C]

Alternate protein names: NA

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MEDKYMESNDVPVLIVGGGLSGLASALFLAKHNIEYLLIERHPSTAIHPKAGGITFRTMELFRELGLEQRIRSAGKTLEN
CRGRIAVHTIAEANQEEFAQLRVTQYENDEKLLQKVKEISPSKQTACYQIILEEMMLQEAKTLGGQLSFYHELVSFEQNE
NGVKATIRNRETKKEGVIHCDYVIAADGAKSKIREQLGISTEGRGTIGGYYMNIYFEADLSEFIQGDAFGFSMVLHPEVL
GALIPVDNERRWIYHVSYDPLKGEQPEDFTIERCKQIIQTAIGSTNVESEIVSVLPWEATESTATKFQDNRIFLVGDSAH
IMPPTGGLGSNTGIQDAHNLAWKLAAVIKGKANPKLLETYHKERYPVAKLTTDYASSLLFRAANREEGSLNKMDGLAVTA
GYHYSSDAIIDDDSVTPHRMDIVQLNGRPGTRAPHFIGMYEEKEVSVLDLLGNDFVLLTGAENDSWAESAHTVSAKLGVN
IKVYRVGLSGDFIAQENVFSELYGLSDGGAVLIRPDAFIGWRSEKEVVNLDVVLEEVMGNLLCDF

Sequences:

>Translated_545_residues
MEDKYMESNDVPVLIVGGGLSGLASALFLAKHNIEYLLIERHPSTAIHPKAGGITFRTMELFRELGLEQRIRSAGKTLEN
CRGRIAVHTIAEANQEEFAQLRVTQYENDEKLLQKVKEISPSKQTACYQIILEEMMLQEAKTLGGQLSFYHELVSFEQNE
NGVKATIRNRETKKEGVIHCDYVIAADGAKSKIREQLGISTEGRGTIGGYYMNIYFEADLSEFIQGDAFGFSMVLHPEVL
GALIPVDNERRWIYHVSYDPLKGEQPEDFTIERCKQIIQTAIGSTNVESEIVSVLPWEATESTATKFQDNRIFLVGDSAH
IMPPTGGLGSNTGIQDAHNLAWKLAAVIKGKANPKLLETYHKERYPVAKLTTDYASSLLFRAANREEGSLNKMDGLAVTA
GYHYSSDAIIDDDSVTPHRMDIVQLNGRPGTRAPHFIGMYEEKEVSVLDLLGNDFVLLTGAENDSWAESAHTVSAKLGVN
IKVYRVGLSGDFIAQENVFSELYGLSDGGAVLIRPDAFIGWRSEKEVVNLDVVLEEVMGNLLCDF
>Mature_545_residues
MEDKYMESNDVPVLIVGGGLSGLASALFLAKHNIEYLLIERHPSTAIHPKAGGITFRTMELFRELGLEQRIRSAGKTLEN
CRGRIAVHTIAEANQEEFAQLRVTQYENDEKLLQKVKEISPSKQTACYQIILEEMMLQEAKTLGGQLSFYHELVSFEQNE
NGVKATIRNRETKKEGVIHCDYVIAADGAKSKIREQLGISTEGRGTIGGYYMNIYFEADLSEFIQGDAFGFSMVLHPEVL
GALIPVDNERRWIYHVSYDPLKGEQPEDFTIERCKQIIQTAIGSTNVESEIVSVLPWEATESTATKFQDNRIFLVGDSAH
IMPPTGGLGSNTGIQDAHNLAWKLAAVIKGKANPKLLETYHKERYPVAKLTTDYASSLLFRAANREEGSLNKMDGLAVTA
GYHYSSDAIIDDDSVTPHRMDIVQLNGRPGTRAPHFIGMYEEKEVSVLDLLGNDFVLLTGAENDSWAESAHTVSAKLGVN
IKVYRVGLSGDFIAQENVFSELYGLSDGGAVLIRPDAFIGWRSEKEVVNLDVVLEEVMGNLLCDF

Specific function: Involved in developmentally regulated synthesis of a compound biosynthetically related to polyketide antibiotics which is essential for spore color in Streptomyces halstedii [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pheA/tfdB FAD monooxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786543, Length=401, Percent_Identity=24.9376558603491, Blast_Score=104, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.- [C]

Molecular weight: Translated: 60461; Mature: 60461

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDKYMESNDVPVLIVGGGLSGLASALFLAKHNIEYLLIERHPSTAIHPKAGGITFRTME
CCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEHHHHH
LFRELGLEQRIRSAGKTLENCRGRIAVHTIAEANQEEFAQLRVTQYENDEKLLQKVKEIS
HHHHCCHHHHHHHHHHHHHHCCCEEEEEEEHHCCHHHHHHEEEEECCCHHHHHHHHHHCC
PSKQTACYQIILEEMMLQEAKTLGGQLSFYHELVSFEQNENGVKATIRNRETKKEGVIHC
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEE
DYVIAADGAKSKIREQLGISTEGRGTIGGYYMNIYFEADLSEFIQGDAFGFSMVLHPEVL
EEEEECCCCHHHHHHHHCCCCCCCCCCCEEEEEEEEECCHHHHHCCCCCCEEEEECHHHH
GALIPVDNERRWIYHVSYDPLKGEQPEDFTIERCKQIIQTAIGSTNVESEIVSVLPWEAT
HEEECCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCC
ESTATKFQDNRIFLVGDSAHIMPPTGGLGSNTGIQDAHNLAWKLAAVIKGKANPKLLETY
CHHHHEECCCEEEEEECCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHH
HKERYPVAKLTTDYASSLLFRAANREEGSLNKMDGLAVTAGYHYSSDAIIDDDSVTPHRM
HHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCEECCCCEECCCCCCCCEE
DIVQLNGRPGTRAPHFIGMYEEKEVSVLDLLGNDFVLLTGAENDSWAESAHTVSAKLGVN
EEEEECCCCCCCCCCEEECCCCCCCEEEEECCCCEEEEECCCCCCHHHHHHEEEEEECCE
IKVYRVGLSGDFIAQENVFSELYGLSDGGAVLIRPDAFIGWRSEKEVVNLDVVLEEVMGN
EEEEEEECCCCCEEHHHHHHHHHCCCCCCEEEECCCCEECCCCCCCEEHHHHHHHHHHHH
LLCDF
HHCCC
>Mature Secondary Structure
MEDKYMESNDVPVLIVGGGLSGLASALFLAKHNIEYLLIERHPSTAIHPKAGGITFRTME
CCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEHHHHH
LFRELGLEQRIRSAGKTLENCRGRIAVHTIAEANQEEFAQLRVTQYENDEKLLQKVKEIS
HHHHCCHHHHHHHHHHHHHHCCCEEEEEEEHHCCHHHHHHEEEEECCCHHHHHHHHHHCC
PSKQTACYQIILEEMMLQEAKTLGGQLSFYHELVSFEQNENGVKATIRNRETKKEGVIHC
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEE
DYVIAADGAKSKIREQLGISTEGRGTIGGYYMNIYFEADLSEFIQGDAFGFSMVLHPEVL
EEEEECCCCHHHHHHHHCCCCCCCCCCCEEEEEEEEECCHHHHHCCCCCCEEEEECHHHH
GALIPVDNERRWIYHVSYDPLKGEQPEDFTIERCKQIIQTAIGSTNVESEIVSVLPWEAT
HEEECCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCC
ESTATKFQDNRIFLVGDSAHIMPPTGGLGSNTGIQDAHNLAWKLAAVIKGKANPKLLETY
CHHHHEECCCEEEEEECCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHH
HKERYPVAKLTTDYASSLLFRAANREEGSLNKMDGLAVTAGYHYSSDAIIDDDSVTPHRM
HHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCEECCCCEECCCCCCCCEE
DIVQLNGRPGTRAPHFIGMYEEKEVSVLDLLGNDFVLLTGAENDSWAESAHTVSAKLGVN
EEEEECCCCCCCCCCEEECCCCCCCEEEEECCCCEEEEECCCCCCHHHHHHEEEEEECCE
IKVYRVGLSGDFIAQENVFSELYGLSDGGAVLIRPDAFIGWRSEKEVVNLDVVLEEVMGN
EEEEEEECCCCCEEHHHHHHHHHCCCCCCEEEECCCCEECCCCCCCEEHHHHHHHHHHHH
LLCDF
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3-(3-hydroxyphenyl)propionate; NADH; O2 [C]

Specific reaction: 3-(3-hydroxyphenyl)propionate + NADH + O2 = H2O + 3-(2,3-dihydroxyphenyl)propionate + NAD [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8253693; 8344517 [H]