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The map label for this gene is yueD [H]

Identifier: 52141987

GI number: 52141987

Start: 3383016

End: 3383765

Strand: Direct

Name: yueD [H]

Synonym: BCZK3256

Alternate gene names: 52141987

Gene position: 3383016-3383765 (Clockwise)

Preceding gene: 52141988

Following gene: 52141980

Centisome position: 63.82

GC content: 35.07

Gene sequence:

>750_bases
ATGCGCTACGTTATTATAACAGGAACTTCACAAGGTTTAGGTGAGGCTATTGCCACACAATTGTTAGAAAAAAATACAAC
TGTCATCTCTATTTCTAGAAGAGAAAATAAAGAGCTTACGAAACTCGCAGAACAATATAATAGCAATTGTGTTTTCTACT
CCTTAGATCTTCAAGATGTACATAATTTAGAAACAAACTTTAAAGAAATTCTTTCATCTATTAAAGAAAACAGCGTATCC
GCTATTCATTTAATTAATAATGCGGGTACAGTTGCTCCTATGAAGCCAATTGAAAAAGCAGAAAGTGAACAATTCATTAC
GAACGTTCACATTAATTTACTTGCGCCTATGATTCTTACATCTACTTTCATGAAATATACAACAGACTGGAAAGTAGATA
AACGCGTTATAAATATTTCATCTGGCGCAGGAAAAAACCCTTATTTCGGATGGGGCGCTTATTGTACGACGAAAGCTGGT
GTAAATATGTTTACACAGTGCGTAGCAACCGAAGAGGTAGAAAAAGAATATCCCGTAAAAATCGTCGCTTTTGCGCCTGG
TGTTGTTGACACTAATATGCAAGCACAAATTCGTGAAACAAATAAAGAAGACTTCACAAATTTAGACCGCTTCATCGCAT
TAAAAGAAGAAGGAAAGCTATTATCACCTGAATATGTCGCGAAAGCTATTCGTAATTTACTAGAAACTGAAGACTTCCCT
CAAGGCGAAGTTATTAGAATTGATGAATAA

Upstream 100 bases:

>100_bases
AATTATAGTAAAAATTGCTCTATACTATAAAATGTAGACAAACTATACAATGTACGTTGTCCAACAAAATTCCGCACATA
TGAGAGGAGTTTATAAAACT

Downstream 100 bases:

>100_bases
CAAAAAGGCGCGCTATTTTAGCACGCCTTTTTGTTCTACTTCTCTAAAAATATAAGAAGAGACTCCGCAATTTGTTCATA
ACCAATTTCTTGATAAATTT

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MRYVIITGTSQGLGEAIATQLLEKNTTVISISRRENKELTKLAEQYNSNCVFYSLDLQDVHNLETNFKEILSSIKENSVS
AIHLINNAGTVAPMKPIEKAESEQFITNVHINLLAPMILTSTFMKYTTDWKVDKRVINISSGAGKNPYFGWGAYCTTKAG
VNMFTQCVATEEVEKEYPVKIVAFAPGVVDTNMQAQIRETNKEDFTNLDRFIALKEEGKLLSPEYVAKAIRNLLETEDFP
QGEVIRIDE

Sequences:

>Translated_249_residues
MRYVIITGTSQGLGEAIATQLLEKNTTVISISRRENKELTKLAEQYNSNCVFYSLDLQDVHNLETNFKEILSSIKENSVS
AIHLINNAGTVAPMKPIEKAESEQFITNVHINLLAPMILTSTFMKYTTDWKVDKRVINISSGAGKNPYFGWGAYCTTKAG
VNMFTQCVATEEVEKEYPVKIVAFAPGVVDTNMQAQIRETNKEDFTNLDRFIALKEEGKLLSPEYVAKAIRNLLETEDFP
QGEVIRIDE
>Mature_249_residues
MRYVIITGTSQGLGEAIATQLLEKNTTVISISRRENKELTKLAEQYNSNCVFYSLDLQDVHNLETNFKEILSSIKENSVS
AIHLINNAGTVAPMKPIEKAESEQFITNVHINLLAPMILTSTFMKYTTDWKVDKRVINISSGAGKNPYFGWGAYCTTKAG
VNMFTQCVATEEVEKEYPVKIVAFAPGVVDTNMQAQIRETNKEDFTNLDRFIALKEEGKLLSPEYVAKAIRNLLETEDFP
QGEVIRIDE

Specific function: Reduces benzil stereospecifically to (S)-benzoin. Can also reduces 1-phenyl-1,2-propanedione, 1,4-naphthoquinone, 1-(4- methyl-phenyl)-2-phenyl-ethane-1,2-dione, 1-(4-fluoro-phenyl)-2- phenyl-ethane-1,2-dione, methyl benzoylformate, p- nitrobenzaldehyde i

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4507185, Length=253, Percent_Identity=29.6442687747036, Blast_Score=94, Evalue=9e-20,
Organism=Homo sapiens, GI150247226, Length=223, Percent_Identity=27.3542600896861, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=24.2798353909465, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI22507405, Length=204, Percent_Identity=25.4901960784314, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI109715829, Length=243, Percent_Identity=25.9259259259259, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787820, Length=195, Percent_Identity=27.6923076923077, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=23.7903225806452, Blast_Score=62, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=259, Percent_Identity=28.957528957529, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=193, Percent_Identity=26.4248704663212, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=26.5625, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322227, Length=242, Percent_Identity=30.5785123966942, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6322226, Length=246, Percent_Identity=28.0487804878049, Blast_Score=90, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24640597, Length=258, Percent_Identity=27.906976744186, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=27.710843373494, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24643142, Length=194, Percent_Identity=25.7731958762887, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27968; Mature: 27968

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYVIITGTSQGLGEAIATQLLEKNTTVISISRRENKELTKLAEQYNSNCVFYSLDLQDV
CEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECHHHH
HNLETNFKEILSSIKENSVSAIHLINNAGTVAPMKPIEKAESEQFITNVHINLLAPMILT
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHH
STFMKYTTDWKVDKRVINISSGAGKNPYFGWGAYCTTKAGVNMFTQCVATEEVEKEYPVK
HHHHHHCCCCEECEEEEEECCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHCCEE
IVAFAPGVVDTNMQAQIRETNKEDFTNLDRFIALKEEGKLLSPEYVAKAIRNLLETEDFP
EEEECCCEECCCCHHHHHHCCHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHCCCCCC
QGEVIRIDE
CCCEEEECC
>Mature Secondary Structure
MRYVIITGTSQGLGEAIATQLLEKNTTVISISRRENKELTKLAEQYNSNCVFYSLDLQDV
CEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECHHHH
HNLETNFKEILSSIKENSVSAIHLINNAGTVAPMKPIEKAESEQFITNVHINLLAPMILT
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHH
STFMKYTTDWKVDKRVINISSGAGKNPYFGWGAYCTTKAGVNMFTQCVATEEVEKEYPVK
HHHHHHCCCCEECEEEEEECCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHCCEE
IVAFAPGVVDTNMQAQIRETNKEDFTNLDRFIALKEEGKLLSPEYVAKAIRNLLETEDFP
EEEECCCEECCCCHHHHHHCCHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHCCCCCC
QGEVIRIDE
CCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11745140; 11796169 [H]