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The map label for this gene is mrp [H]

Identifier: 52141972

GI number: 52141972

Start: 3397799

End: 3398848

Strand: Reverse

Name: mrp [H]

Synonym: BCZK3271

Alternate gene names: 52141972

Gene position: 3398848-3397799 (Counterclockwise)

Preceding gene: 52141969

Following gene: 52141974

Centisome position: 64.12

GC content: 37.43

Gene sequence:

>1050_bases
ATGCTTACTCAAGAACAAATAATGAATGCGTTAAAACATGTAGAGGATCCAGAATTACACAAAAGTATTGTAGAGTTAAA
CATGGTTAGAAATATACAAATGAATGGAACAGAGGTTAAACTTGAAGTAGTGCTAACGATTCAAGGTTGTCCGTTAAAAG
CAAAAATTCAACAAGATATTGAAGAATCACTTTACGCAATTGGTGCATCTAAAGTAGATTTAACATTCGGTTCTATGACA
AAAGAAGAACGTGCAGACTTAACAGAGAAGTTAAAGAAAAATACTAGAACAGAAACTGGTATGCCGAACATGCTCCGTCC
GGATTCAGGGGTACAATTTCTTACTGTAACGAGTGGAAAAGGTGGAGTCGGAAAATCGACTGTGACAATTAATCTTGCAA
CGGCTTTAGCTCGTATGGGCAAAAAAGTGGGGATATTAGATGCAGATATATATGGTTTTAGCATTCCAGCTATGATGGAA
ACGAAGCAAAAACCAACGATGATTGATCAAACAGCAATTCCGGTAATTAGTCACGGTGTTAAAATTATGTCTATGGGATT
TTTTACAGAAGGAAATAATCCGGTTATGTGGCGCGGACCGATGTTAAATAAATGGATTCAAAATTTCCTTGCGAATACGC
ACTGGGGAGAATTAGATTATTTACTTCTTGATTTACCACCTGGTACAGGAGATGTTGCCATTGATGTTGCAGCAATGATT
CCGCAGGCGAAAGAAATTATCGTTACAACTCCGCACAATGTAGCTTCATTCGTAGCATCTAGAGTAGGCGTAATGGCAAA
ACATACGAAACACGAGATTTTAGGTATTGTGGAAAACATGGCTTATTACGAAGAACAAGATGGATCGAAAAATTATCTGT
TCGGCAAAGGCGGCGGCGAAATGTTGGCAGAACAATTGAAAACAGAAGTAATCGCACAAGTACCTTTTGCAAAACGTGAA
GAAAATAACGGTTCATCTGTATATGATGAAGATTCTCTTGTTGGAGAAGTGTTTACAGCGTTAGCAGAAGATATTATTTA
TAAAGGATAG

Upstream 100 bases:

>100_bases
GATCCCCCACCTAACTTCTCTGCTTTCGCTGAATTTTGAGGTGGGGGTCTTACTGCCCATTAAAGTCGGATAAATTCGAA
TATGAGAAGGGATGAGTTCT

Downstream 100 bases:

>100_bases
AGGAGGAATTTTATTATGGGGTGTAATATCGATCATTCTATTGAAGATGTAATGAATAAGTTTGAAAGTCAAAAGAGTTT
TTTACCGGAAGTGATTTTTA

Product: ATP-binding mrp protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MLTQEQIMNALKHVEDPELHKSIVELNMVRNIQMNGTEVKLEVVLTIQGCPLKAKIQQDIEESLYAIGASKVDLTFGSMT
KEERADLTEKLKKNTRTETGMPNMLRPDSGVQFLTVTSGKGGVGKSTVTINLATALARMGKKVGILDADIYGFSIPAMME
TKQKPTMIDQTAIPVISHGVKIMSMGFFTEGNNPVMWRGPMLNKWIQNFLANTHWGELDYLLLDLPPGTGDVAIDVAAMI
PQAKEIIVTTPHNVASFVASRVGVMAKHTKHEILGIVENMAYYEEQDGSKNYLFGKGGGEMLAEQLKTEVIAQVPFAKRE
ENNGSSVYDEDSLVGEVFTALAEDIIYKG

Sequences:

>Translated_349_residues
MLTQEQIMNALKHVEDPELHKSIVELNMVRNIQMNGTEVKLEVVLTIQGCPLKAKIQQDIEESLYAIGASKVDLTFGSMT
KEERADLTEKLKKNTRTETGMPNMLRPDSGVQFLTVTSGKGGVGKSTVTINLATALARMGKKVGILDADIYGFSIPAMME
TKQKPTMIDQTAIPVISHGVKIMSMGFFTEGNNPVMWRGPMLNKWIQNFLANTHWGELDYLLLDLPPGTGDVAIDVAAMI
PQAKEIIVTTPHNVASFVASRVGVMAKHTKHEILGIVENMAYYEEQDGSKNYLFGKGGGEMLAEQLKTEVIAQVPFAKRE
ENNGSSVYDEDSLVGEVFTALAEDIIYKG
>Mature_349_residues
MLTQEQIMNALKHVEDPELHKSIVELNMVRNIQMNGTEVKLEVVLTIQGCPLKAKIQQDIEESLYAIGASKVDLTFGSMT
KEERADLTEKLKKNTRTETGMPNMLRPDSGVQFLTVTSGKGGVGKSTVTINLATALARMGKKVGILDADIYGFSIPAMME
TKQKPTMIDQTAIPVISHGVKIMSMGFFTEGNNPVMWRGPMLNKWIQNFLANTHWGELDYLLLDLPPGTGDVAIDVAAMI
PQAKEIIVTTPHNVASFVASRVGVMAKHTKHEILGIVENMAYYEEQDGSKNYLFGKGGGEMLAEQLKTEVIAQVPFAKRE
ENNGSSVYDEDSLVGEVFTALAEDIIYKG

Specific function: Negatively regulates the expression of hpr/scoC. The effect on hpr/scoC may be indirect [H]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI157384956, Length=234, Percent_Identity=39.7435897435897, Blast_Score=165, Evalue=5e-41,
Organism=Homo sapiens, GI6912540, Length=214, Percent_Identity=38.3177570093458, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI118572611, Length=215, Percent_Identity=33.953488372093, Blast_Score=114, Evalue=1e-25,
Organism=Escherichia coli, GI87082045, Length=314, Percent_Identity=35.6687898089172, Blast_Score=174, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI25143050, Length=251, Percent_Identity=36.6533864541833, Blast_Score=131, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6322188, Length=244, Percent_Identity=36.8852459016393, Blast_Score=138, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6321347, Length=262, Percent_Identity=32.4427480916031, Blast_Score=106, Evalue=5e-24,
Organism=Drosophila melanogaster, GI221511043, Length=253, Percent_Identity=39.1304347826087, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24667611, Length=246, Percent_Identity=37.3983739837398, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI19921440, Length=222, Percent_Identity=33.3333333333333, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR000808 [H]

Pfam domain/function: PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 38338; Mature: 38338

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTQEQIMNALKHVEDPELHKSIVELNMVRNIQMNGTEVKLEVVLTIQGCPLKAKIQQDI
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHEEEECCCEEEEEEEEEEECCCCHHHHHHHH
EESLYAIGASKVDLTFGSMTKEERADLTEKLKKNTRTETGMPNMLRPDSGVQFLTVTSGK
HHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCC
GGVGKSTVTINLATALARMGKKVGILDADIYGFSIPAMMETKQKPTMIDQTAIPVISHGV
CCCCCEEEEEEHHHHHHHCCCCCCEEECCCCCCCCCHHHHCCCCCCEECHHHHHHHHCCE
KIMSMGFFTEGNNPVMWRGPMLNKWIQNFLANTHWGELDYLLLDLPPGTGDVAIDVAAMI
EEEEEEEEECCCCEEEEECHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEHHHHC
PQAKEIIVTTPHNVASFVASRVGVMAKHTKHEILGIVENMAYYEEQDGSKNYLFGKGGGE
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHH
MLAEQLKTEVIAQVPFAKREENNGSSVYDEDSLVGEVFTALAEDIIYKG
HHHHHHHHHHHHHCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLTQEQIMNALKHVEDPELHKSIVELNMVRNIQMNGTEVKLEVVLTIQGCPLKAKIQQDI
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHEEEECCCEEEEEEEEEEECCCCHHHHHHHH
EESLYAIGASKVDLTFGSMTKEERADLTEKLKKNTRTETGMPNMLRPDSGVQFLTVTSGK
HHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCC
GGVGKSTVTINLATALARMGKKVGILDADIYGFSIPAMMETKQKPTMIDQTAIPVISHGV
CCCCCEEEEEEHHHHHHHCCCCCCEEECCCCCCCCCHHHHCCCCCCEECHHHHHHHHCCE
KIMSMGFFTEGNNPVMWRGPMLNKWIQNFLANTHWGELDYLLLDLPPGTGDVAIDVAAMI
EEEEEEEEECCCCEEEEECHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEHHHHC
PQAKEIIVTTPHNVASFVASRVGVMAKHTKHEILGIVENMAYYEEQDGSKNYLFGKGGGE
CCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHH
MLAEQLKTEVIAQVPFAKREENNGSSVYDEDSLVGEVFTALAEDIIYKG
HHHHHHHHHHHHHCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7559346; 8969501; 9384377; 2517635 [H]