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The map label for this gene is mhqO [H]

Identifier: 52141900

GI number: 52141900

Start: 3477309

End: 3478247

Strand: Reverse

Name: mhqO [H]

Synonym: BCZK3346

Alternate gene names: 52141900

Gene position: 3478247-3477309 (Counterclockwise)

Preceding gene: 52141901

Following gene: 52141899

Centisome position: 65.62

GC content: 37.7

Gene sequence:

>939_bases
ATGGAAAAGAAAACAATGGGAATTCATCACATTACAGCAATTGTAGGACATCCACAAGAAAATGTAGATTTTTATGCTGG
TGTATTAGGGTTACGTTTAGTGAAACAAACAGTGAATTTTGATGATCCAGGTACGTACCATCTTTATTTCGGTAATGAAG
GAGGAAAGCCTGGAACAATCATTACGTTTTTCCCATGGGCAGGTGCTCGTCAAGGAATTATTGGTGACGGTCAAGTAGGA
ATCACTTCTTATGTTGTACCAAAAGGGGCAATGAAATTTTGGGAAAATAGATTAGAAAAATTCGATATTTCGTATACAAA
AATGACTCGATTTGGAGAACAATACTTAGAATTTGATGATCCGCATGGTTTGCATATAGAATTAGTAGAAAGAGAAGAAG
GCGAATTAAATAATTGGAGCTTTGGGGAAGTTACGCCAGAAGTAGCAATTAAAGGATTTGGTGGTGCTGTTCTTTTATCA
GCGCACCCTCAAAAAACTGCTGAATTGTTAGAGCACGTTATGGGTCTTGAGAAAATTGGGGAAGAGGGCGAATTTGTTCG
ATTCCGTTCTTCTGCTGATATTGGAAATATTATTGATTTGAAATTATCGACAATTGGACGTGGCCAGATGGGTGTTGGTA
CAGTCCATCATATTGCTTGGAGAGCGAGTGATGATGCTGATCAGTTAGACTGGAAAGAGCACGTATCCCGCTTTGGATAC
CACGTAACTCCTGTACAAGACCGAAATTATTTTAACGCAATTTATTTTAGAGAACACGGTGAAATTTTATTTGAAATTGC
AACAGATCCTCCTGGTTTCGCTCATGATGAATCGTTAGAGACGATGGGTGAGGAATTAAAGTTACCGGAACAATATGAAC
AACATAGAAAACAGATTGAACAAACGCTTTTACCATTTGAAGTGAGAAATTTAGATTAA

Upstream 100 bases:

>100_bases
AATTATAATTCAGGATTTTACTTTATCGTATGGACAAAATAAATAATGAATTTTAATGTAAAAAAATTTTTCATAATGAA
TTAAAAAAGGAGTGGAGAAA

Downstream 100 bases:

>100_bases
AGTGATTGAAAGGGGAACAGAATTATGATGAAACATGTTTTTCAAAAAGGAAAAGATACGTCAAAACCAGTGTTATTATT
ACTTCATGGTACAGGAGGTA

Product: glyoxalase/bleomycin resistance protein

Products: glutathione; methylglyoxal

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MEKKTMGIHHITAIVGHPQENVDFYAGVLGLRLVKQTVNFDDPGTYHLYFGNEGGKPGTIITFFPWAGARQGIIGDGQVG
ITSYVVPKGAMKFWENRLEKFDISYTKMTRFGEQYLEFDDPHGLHIELVEREEGELNNWSFGEVTPEVAIKGFGGAVLLS
AHPQKTAELLEHVMGLEKIGEEGEFVRFRSSADIGNIIDLKLSTIGRGQMGVGTVHHIAWRASDDADQLDWKEHVSRFGY
HVTPVQDRNYFNAIYFREHGEILFEIATDPPGFAHDESLETMGEELKLPEQYEQHRKQIEQTLLPFEVRNLD

Sequences:

>Translated_312_residues
MEKKTMGIHHITAIVGHPQENVDFYAGVLGLRLVKQTVNFDDPGTYHLYFGNEGGKPGTIITFFPWAGARQGIIGDGQVG
ITSYVVPKGAMKFWENRLEKFDISYTKMTRFGEQYLEFDDPHGLHIELVEREEGELNNWSFGEVTPEVAIKGFGGAVLLS
AHPQKTAELLEHVMGLEKIGEEGEFVRFRSSADIGNIIDLKLSTIGRGQMGVGTVHHIAWRASDDADQLDWKEHVSRFGY
HVTPVQDRNYFNAIYFREHGEILFEIATDPPGFAHDESLETMGEELKLPEQYEQHRKQIEQTLLPFEVRNLD
>Mature_312_residues
MEKKTMGIHHITAIVGHPQENVDFYAGVLGLRLVKQTVNFDDPGTYHLYFGNEGGKPGTIITFFPWAGARQGIIGDGQVG
ITSYVVPKGAMKFWENRLEKFDISYTKMTRFGEQYLEFDDPHGLHIELVEREEGELNNWSFGEVTPEVAIKGFGGAVLLS
AHPQKTAELLEHVMGLEKIGEEGEFVRFRSSADIGNIIDLKLSTIGRGQMGVGTVHHIAWRASDDADQLDWKEHVSRFGY
HVTPVQDRNYFNAIYFREHGEILFEIATDPPGFAHDESLETMGEELKLPEQYEQHRKQIEQTLLPFEVRNLD

Specific function: Putative ring-cleavage dioxygenase that may contribute to the degradation of aromatic compounds (Potential) [H]

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the extradiol ring-cleavage dioxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 4.4.1.5

Molecular weight: Translated: 35361; Mature: 35361

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKKTMGIHHITAIVGHPQENVDFYAGVLGLRLVKQTVNFDDPGTYHLYFGNEGGKPGTI
CCCCCCCHHEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEE
ITFFPWAGARQGIIGDGQVGITSYVVPKGAMKFWENRLEKFDISYTKMTRFGEQYLEFDD
EEEECCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
PHGLHIELVEREEGELNNWSFGEVTPEVAIKGFGGAVLLSAHPQKTAELLEHVMGLEKIG
CCCCEEEEEECCCCCCCCCCCCCCCHHHEEECCCCEEEEECCCHHHHHHHHHHHHHHHHC
EEGEFVRFRSSADIGNIIDLKLSTIGRGQMGVGTVHHIAWRASDDADQLDWKEHVSRFGY
CCCCEEEEECCCCCCCEEEEEEEECCCCCCCCCHHHHEEEECCCCCCCCCHHHHHHHCCC
HVTPVQDRNYFNAIYFREHGEILFEIATDPPGFAHDESLETMGEELKLPEQYEQHRKQIE
EECEECCCCCEEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHH
QTLLPFEVRNLD
HHHCCEEECCCC
>Mature Secondary Structure
MEKKTMGIHHITAIVGHPQENVDFYAGVLGLRLVKQTVNFDDPGTYHLYFGNEGGKPGTI
CCCCCCCHHEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEE
ITFFPWAGARQGIIGDGQVGITSYVVPKGAMKFWENRLEKFDISYTKMTRFGEQYLEFDD
EEEECCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
PHGLHIELVEREEGELNNWSFGEVTPEVAIKGFGGAVLLSAHPQKTAELLEHVMGLEKIG
CCCCEEEEEECCCCCCCCCCCCCCCHHHEEECCCCEEEEECCCHHHHHHHHHHHHHHHHC
EEGEFVRFRSSADIGNIIDLKLSTIGRGQMGVGTVHHIAWRASDDADQLDWKEHVSRFGY
CCCCEEEEECCCCCCCEEEEEEEECCCCCCCCCHHHHEEEECCCCCCCCCHHHHHHHCCC
HVTPVQDRNYFNAIYFREHGEILFEIATDPPGFAHDESLETMGEELKLPEQYEQHRKQIE
EECEECCCCCEEEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHH
QTLLPFEVRNLD
HHHCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]