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The map label for this gene is hutI [H]

Identifier: 52141892

GI number: 52141892

Start: 3485375

End: 3486646

Strand: Reverse

Name: hutI [H]

Synonym: BCZK3352

Alternate gene names: 52141892

Gene position: 3486646-3485375 (Counterclockwise)

Preceding gene: 52141893

Following gene: 52141891

Centisome position: 65.77

GC content: 40.09

Gene sequence:

>1272_bases
ATGCTGGACACTTTACTAATCAATATCGGTCAATTACTAACAATGGATCAAGAAGATGGCTTGTTAAGACGGGAAGCGAT
GAACACGCTTCCTGTTATCGAAAATGGTGCGGTTGGAATTGAAAACGGCGTAATTACTTTCGTTGGAACAGTGGAAGAAG
CAAAAGGGTTACAAGCGAAAGAGGTTATTGATTGCGGCGGAAAAATGGTTTCTCCTGGCCTTGTTGACCCGCATACTCAT
CTTGTATTTGGTGGATCTCGTGAAAATGAAATCGCACTAAAATTACAAGGAGTTCCGTACTTAGAAATTTTAGAAAAAGG
CGGAGGTATTCTTTCAACTGTAAATGCAACGAAACAAGCGTCGAAAGAAGAACTCGTTCAAAAAGCGAAATTCCATTTAG
ACCGTATGCTATCTTTCGGAGTTACAACTGTAGAAGCGAAGAGTGGTTATGGATTAGATGATGAGACGGAATGGAAACAA
TTAGAGGCAACTGCACAATTACAAAAAGAACATCCAATCGATTTAGTGTCAACGTTTTTAGGTGCTCATGCAGTTCCGAA
GGAGTACAAAGGTAGATCAAAAGAATTTTTACAATGGATGTTAGACCTACTACCAGAAATGAAAGAGAAGCAATTAGCAG
AATTCGTTGATATTTTCTGCGAAACAGGTGTGTTCTCTGTCGAAGAATCAAAAGATTTTTTATTAAAAGCGAAAGAGCTT
GGCTTTGATGTGAAAATTCATGCGGATGAAATTGATCCTCTTGGTGGTGCGGAAGCAGCAGCTGAAATTGGTGCAGCATC
AGCGGACCATTTAGTTGGTGCTTCTGATAAAGGAATTGAAATGCTTGCAAACTCTAATACAGTAGCCACTTTATTACCAG
GAACAACTTTCTATTTAAATAAAGAAAGCTTTGCTCGCGGTCGTAAAATGATCGATGAAGGTGTTGCGGTAGCTTTAGCC
ACAGACTTTAACCCAGGCAGCTGCCCAACTGAAAACATTCAGCTTATTATGAGCATCGCAATGCTGAAATTGAAAATGAC
ACCAGAGGAAGTTTGGAATGCTGTAACAGTTAACTCTTCTTACGCGATTAATCGTGGTGAGGTAGCTGGGAAAATTAGAG
TTGGTCGCAAGGCAGATTTAGTGTTATGGGATGCTTACAACTATGCTTACGTACCGTATCATTACGGCGTAAGTCATGTA
AATACAGTCTGGAAGAATGGTAATATCGCATATACAAGAGGTGAACAATCGTGGAGCACGGCCACTATTTAA

Upstream 100 bases:

>100_bases
GGGAGTTGTTCGTCACGTTGATGCAGGGTATGACTTAGCTGTGGAAACTGCGAAAGAAAAAGGCGTTAACATTCCAATGA
TGAAATAAGGAGGAGAAAAC

Downstream 100 bases:

>100_bases
AGAAAAATGCAAAGTTTATTGATCGTGAAGTAACGAAATGGAGTGAGATGATTAAAGATTGGGAGGAAGGCGTGGAAATA
TTCGGTGCTGCCTTAATTGG

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase [H]

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MLDTLLINIGQLLTMDQEDGLLRREAMNTLPVIENGAVGIENGVITFVGTVEEAKGLQAKEVIDCGGKMVSPGLVDPHTH
LVFGGSRENEIALKLQGVPYLEILEKGGGILSTVNATKQASKEELVQKAKFHLDRMLSFGVTTVEAKSGYGLDDETEWKQ
LEATAQLQKEHPIDLVSTFLGAHAVPKEYKGRSKEFLQWMLDLLPEMKEKQLAEFVDIFCETGVFSVEESKDFLLKAKEL
GFDVKIHADEIDPLGGAEAAAEIGAASADHLVGASDKGIEMLANSNTVATLLPGTTFYLNKESFARGRKMIDEGVAVALA
TDFNPGSCPTENIQLIMSIAMLKLKMTPEEVWNAVTVNSSYAINRGEVAGKIRVGRKADLVLWDAYNYAYVPYHYGVSHV
NTVWKNGNIAYTRGEQSWSTATI

Sequences:

>Translated_423_residues
MLDTLLINIGQLLTMDQEDGLLRREAMNTLPVIENGAVGIENGVITFVGTVEEAKGLQAKEVIDCGGKMVSPGLVDPHTH
LVFGGSRENEIALKLQGVPYLEILEKGGGILSTVNATKQASKEELVQKAKFHLDRMLSFGVTTVEAKSGYGLDDETEWKQ
LEATAQLQKEHPIDLVSTFLGAHAVPKEYKGRSKEFLQWMLDLLPEMKEKQLAEFVDIFCETGVFSVEESKDFLLKAKEL
GFDVKIHADEIDPLGGAEAAAEIGAASADHLVGASDKGIEMLANSNTVATLLPGTTFYLNKESFARGRKMIDEGVAVALA
TDFNPGSCPTENIQLIMSIAMLKLKMTPEEVWNAVTVNSSYAINRGEVAGKIRVGRKADLVLWDAYNYAYVPYHYGVSHV
NTVWKNGNIAYTRGEQSWSTATI
>Mature_423_residues
MLDTLLINIGQLLTMDQEDGLLRREAMNTLPVIENGAVGIENGVITFVGTVEEAKGLQAKEVIDCGGKMVSPGLVDPHTH
LVFGGSRENEIALKLQGVPYLEILEKGGGILSTVNATKQASKEELVQKAKFHLDRMLSFGVTTVEAKSGYGLDDETEWKQ
LEATAQLQKEHPIDLVSTFLGAHAVPKEYKGRSKEFLQWMLDLLPEMKEKQLAEFVDIFCETGVFSVEESKDFLLKAKEL
GFDVKIHADEIDPLGGAEAAAEIGAASADHLVGASDKGIEMLANSNTVATLLPGTTFYLNKESFARGRKMIDEGVAVALA
TDFNPGSCPTENIQLIMSIAMLKLKMTPEEVWNAVTVNSSYAINRGEVAGKIRVGRKADLVLWDAYNYAYVPYHYGVSHV
NTVWKNGNIAYTRGEQSWSTATI

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family [H]

Homologues:

Organism=Homo sapiens, GI223972677, Length=420, Percent_Identity=36.4285714285714, Blast_Score=254, Evalue=1e-67,
Organism=Caenorhabditis elegans, GI17555004, Length=449, Percent_Identity=34.9665924276169, Blast_Score=248, Evalue=4e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.7 [H]

Molecular weight: Translated: 46199; Mature: 46199

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDTLLINIGQLLTMDQEDGLLRREAMNTLPVIENGAVGIENGVITFVGTVEEAKGLQAK
CCCCEEECCHHHEEECCCCCHHHHHHHCCCCEECCCCEEECCCEEEEEEEHHHHCCCCHH
EVIDCGGKMVSPGLVDPHTHLVFGGSRENEIALKLQGVPYLEILEKGGGILSTVNATKQA
HHHHCCCCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCHHHHHHCCCCEEEECCHHHHH
SKEELVQKAKFHLDRMLSFGVTTVEAKSGYGLDDETEWKQLEATAQLQKEHPIDLVSTFL
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
GAHAVPKEYKGRSKEFLQWMLDLLPEMKEKQLAEFVDIFCETGVFSVEESKDFLLKAKEL
CCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHC
GFDVKIHADEIDPLGGAEAAAEIGAASADHLVGASDKGIEMLANSNTVATLLPGTTFYLN
CCEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEECCCEEEEEECCEEEEEC
KESFARGRKMIDEGVAVALATDFNPGSCPTENIQLIMSIAMLKLKMTPEEVWNAVTVNSS
CHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHEECCHHHHCCEEEECCC
YAINRGEVAGKIRVGRKADLVLWDAYNYAYVPYHYGVSHVNTVWKNGNIAYTRGEQSWST
EEECCCCEEEEEEECCCCCEEEEECCCEEEEEEECCCHHHHHHEECCCEEEECCCCCCCC
ATI
CCC
>Mature Secondary Structure
MLDTLLINIGQLLTMDQEDGLLRREAMNTLPVIENGAVGIENGVITFVGTVEEAKGLQAK
CCCCEEECCHHHEEECCCCCHHHHHHHCCCCEECCCCEEECCCEEEEEEEHHHHCCCCHH
EVIDCGGKMVSPGLVDPHTHLVFGGSRENEIALKLQGVPYLEILEKGGGILSTVNATKQA
HHHHCCCCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCHHHHHHCCCCEEEECCHHHHH
SKEELVQKAKFHLDRMLSFGVTTVEAKSGYGLDDETEWKQLEATAQLQKEHPIDLVSTFL
HHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
GAHAVPKEYKGRSKEFLQWMLDLLPEMKEKQLAEFVDIFCETGVFSVEESKDFLLKAKEL
CCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHC
GFDVKIHADEIDPLGGAEAAAEIGAASADHLVGASDKGIEMLANSNTVATLLPGTTFYLN
CCEEEEECCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEECCCEEEEEECCEEEEEC
KESFARGRKMIDEGVAVALATDFNPGSCPTENIQLIMSIAMLKLKMTPEEVWNAVTVNSS
CHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHEECCHHHHCCEEEECCC
YAINRGEVAGKIRVGRKADLVLWDAYNYAYVPYHYGVSHVNTVWKNGNIAYTRGEQSWST
EEECCCCEEEEEEECCCCCEEEEECCCEEEEEEECCCHHHHHHEECCCEEEECCCCCCCC
ATI
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA