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The map label for this gene is ccdA [H]

Identifier: 52141876

GI number: 52141876

Start: 3504506

End: 3505213

Strand: Reverse

Name: ccdA [H]

Synonym: BCZK3367

Alternate gene names: 52141876

Gene position: 3505213-3504506 (Counterclockwise)

Preceding gene: 52141874

Following gene: 52141879

Centisome position: 66.12

GC content: 34.04

Gene sequence:

>708_bases
ATGCAAGATATTAGTATTTTTTTAGCGTTTGGCGCCGGGTTTTTATCATTTATTTCCCCATGTTGCTTGCCGCTTTATCC
CGCATTTCTATCATATATAACAGGTATGTCGGTTTCTGAGCTGAAAGAAGAAAATGCAATGCTTCGCAAAAGAAGTATGA
TACATACAGCGTTTTTCTTACTTGGATTTTCAATTATATTTATTGCAATTGGATTTGGTACAAGTTTTATTGGAGGCATC
TTTACAAATTATAAAGATTTAATTAGACAGCTAGGTGGTATCTTTATTATCGTGTTCGGTCTTATTATTGTTGGTGTGTT
TAAGCCGAAGTTTTTAATGCAAGATCGTAAATTTACGTTTAAAAATCGCCCGAGTGGCTATTTTGGATCTGTTTTAATTG
GTTTAGCATTTGCTGCAGGATGGACACCTTGTACAGGACCTATTTTAGTATCTGTTATTGGATTAGCAGCGACAAACCCA
GAATCAGCAATGATTTATATGATCGCATACATACTTGGATTCGCTATCCCGTTCTTCGTACTATCATTCTTTATTACGAA
AATGTCTTGGATTAAAAGAAACAGTATGAAGTTCATGAAAATCGGGGGATACGTTATGATTATCATGGGTATTTTCTTAT
ACTTTAACTGGATGACGAAAATTATCGTATATTTCTCAAGTTTATTTGGTGGTTTTACTGGTTTTTAG

Upstream 100 bases:

>100_bases
GGCAGTTTTTCTTATTATCACGTTGGAAAAGTGATTTCACGAATTGTTCATAGTATTTTTACGTGTTTTTGCTACAATAT
GTAAGGAGAGGAGTGGAACA

Downstream 100 bases:

>100_bases
TATTATTCTGTGAAAATGTTGGAAATACTAACGGAAAAGCATATAATGAAAGTATATTTTGCATATAGCCACAAAAAAGG
ATGAGAAAATATGAACATAG

Product: cytochrome c-type biogenesis protein (holocytochrome-c synthase)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MQDISIFLAFGAGFLSFISPCCLPLYPAFLSYITGMSVSELKEENAMLRKRSMIHTAFFLLGFSIIFIAIGFGTSFIGGI
FTNYKDLIRQLGGIFIIVFGLIIVGVFKPKFLMQDRKFTFKNRPSGYFGSVLIGLAFAAGWTPCTGPILVSVIGLAATNP
ESAMIYMIAYILGFAIPFFVLSFFITKMSWIKRNSMKFMKIGGYVMIIMGIFLYFNWMTKIIVYFSSLFGGFTGF

Sequences:

>Translated_235_residues
MQDISIFLAFGAGFLSFISPCCLPLYPAFLSYITGMSVSELKEENAMLRKRSMIHTAFFLLGFSIIFIAIGFGTSFIGGI
FTNYKDLIRQLGGIFIIVFGLIIVGVFKPKFLMQDRKFTFKNRPSGYFGSVLIGLAFAAGWTPCTGPILVSVIGLAATNP
ESAMIYMIAYILGFAIPFFVLSFFITKMSWIKRNSMKFMKIGGYVMIIMGIFLYFNWMTKIIVYFSSLFGGFTGF
>Mature_235_residues
MQDISIFLAFGAGFLSFISPCCLPLYPAFLSYITGMSVSELKEENAMLRKRSMIHTAFFLLGFSIIFIAIGFGTSFIGGI
FTNYKDLIRQLGGIFIIVFGLIIVGVFKPKFLMQDRKFTFKNRPSGYFGSVLIGLAFAAGWTPCTGPILVSVIGLAATNP
ESAMIYMIAYILGFAIPFFVLSFFITKMSWIKRNSMKFMKIGGYVMIIMGIFLYFNWMTKIIVYFSSLFGGFTGF

Specific function: Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation [H]

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: NA

Molecular weight: Translated: 26277; Mature: 26277

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDISIFLAFGAGFLSFISPCCLPLYPAFLSYITGMSVSELKEENAMLRKRSMIHTAFFL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LGFSIIFIAIGFGTSFIGGIFTNYKDLIRQLGGIFIIVFGLIIVGVFKPKFLMQDRKFTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCC
KNRPSGYFGSVLIGLAFAAGWTPCTGPILVSVIGLAATNPESAMIYMIAYILGFAIPFFV
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LSFFITKMSWIKRNSMKFMKIGGYVMIIMGIFLYFNWMTKIIVYFSSLFGGFTGF
HHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQDISIFLAFGAGFLSFISPCCLPLYPAFLSYITGMSVSELKEENAMLRKRSMIHTAFFL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
LGFSIIFIAIGFGTSFIGGIFTNYKDLIRQLGGIFIIVFGLIIVGVFKPKFLMQDRKFTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCC
KNRPSGYFGSVLIGLAFAAGWTPCTGPILVSVIGLAATNPESAMIYMIAYILGFAIPFFV
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LSFFITKMSWIKRNSMKFMKIGGYVMIIMGIFLYFNWMTKIIVYFSSLFGGFTGF
HHHHHHHHHHHHHCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969507; 9068642; 9384377; 10781554; 11844773 [H]