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The map label for this gene is pyc [H]

Identifier: 52141541

GI number: 52141541

Start: 3845138

End: 3848584

Strand: Reverse

Name: pyc [H]

Synonym: BCZK3707

Alternate gene names: 52141541

Gene position: 3848584-3845138 (Counterclockwise)

Preceding gene: 52141540

Following gene: 52141542

Centisome position: 72.6

GC content: 37.95

Gene sequence:

>3447_bases
ATGACAAAGCTGCAACGTATTCAAAAAGTATTGGTAGCTAACCGTGGAGAGATTGCAATTCGTGTGTTTCGAGCTTGTTC
GGAACTGGGATTAAAAACAGTTGCAATCTATTCTAAAGAGGATAGTGGTTCTTATCATCGTTATAAAGCCGATGAATCCT
ATTTAGTTGGGGAAGGAAAAAAGCCAATTGATGCTTATCTAGATATTGAAGGCATTATTGAGATTGCGAAAAGTAATCAT
GTAGATGCAATCCACCCTGGATATGGTTTCTTGTCAGAAAATATTCAATTCGCAAAACGTTGTGAAGAAGAAGGGATTAT
CTTTATCGGTCCAAAAAGTAAGCATTTAGATATGTTTGGAGATAAAGTAAAAGCAAGAACACAAGCGCAGCTAGCACAAA
TTCCAGTTATTCCTGGTAGTGATGGGCCAGTAGATTCATTAGAAGAAGTCAAAGAATTTGCTGAAAAGTATGATTACCCG
ATTATTATTAAAGCTTCCCTTGGCGGTGGCGGTCGTGGTATGCGTATTGTACGTAATAGTGAAGAATTAAGAGAATCGTA
TAATCGAGCGAAGTCAGAAGCAAAAGCAGCCTTTGGTAATGATGAAGTATACGTAGAAAAATTCGTTGAAAAACCTAAAC
ATATAGAAGTTCAAATTTTAGCAGATGAAGAGGGCAATGTTGTTCATTTATACGAGCGAGACTGTTCTGTACAACGTCGT
CACCAAAAAGTAGTAGAAATTGCACCTAGTGTGTCGCTTTCAGATGATTTGCGTCAGCGTATTTGTGATGCCGCTGTGAA
ATTAACAAAAAATGTAAATTATTTAAACGCAGGAACAGTTGAATTCCTTGTAAAAGATGATAATTTCTATTTCATTGAAG
TAAATCCGCGTGTTCAAGTAGAACATACAATTACAGAAATGATTACAGGAGTCGATATCGTTCAATCACAAATTTTAATA
GCTGATGGACATGCGTTACATAGCAAATTGGTGGGTGTTCCTAAGCAAGAGGAAGTTGTTGTACATGGATTTGCAATACA
ATCTCGAGTAACGACTGAGGACCCACTAAATAATTTCATGCCAGATACAGGGAAAATTATGGCATATCGATCAGGTGGTG
GCTTTGGGGTTCGTCTTGATACAGGTAATAGTTTCCAAGGTGCTGTTATTACACCGTACTATGATTCTTTACTTGTAAAA
GTTACAACATGGGCGCTTACTTTTGAACAAGCTGCTGCAAAAATGGAACGTAACTTAAAAGAATTCCGTATTCGTGGTAT
TAAAACTAATATTCCATTCCTAGAGAATGTAGTAAAACATAAAAACTTCTTATCAGGGGAATATGACACTTCATTTATTG
ATGCGTCACCTGAACTATTCTTGTTCCCGAAACGTAAAGACCGCGGAACGAAAATGTTAAATTACATCGGGACAGTAACA
GTAAATGGCTTCCCGGGGGTAGGGAAAAAAGAGAAACCAATTTTCCCAGATGCTCGTATACCGAATGTATTACACTCAGA
GCCAATCCAAAATGGAACGAAACAAATTTTGGATGAGCATGGAGCAGACGGATTAGTAAAATGGGTACAAGATCAAAAAC
GTGTACTTTTAACGGATACAACATTCCGTGATGCGCATCAGTCATTACTTGCAACGCGTATTCGTACAAAAGATTTACAT
CAAATTGCAGAGCCAACAGCGAGAATGTTACCGAACTTATTCTCAGCAGAAATGTGGGGCGGTGCAACGTTTGATGTTGC
ATATCGTTTCTTAAAAGAAGATCCGTGGGAACGATTACTAGATCTTCGTGAAAAAATGCCAAATGTTTTATTCCAAATGT
TACTTCGTTCTTCAAATGCAGTTGGTTACAAAAACTATCCGGATAATTTAATTCAAAAGTTTGTGGAGTGTTCTGCTCAA
GCTGGAATTGATGTGTTCCGTATTTTTGATAGCTTAAACTGGGTAGAAGGTATGAGAGTTGCGATTGATGCTGTACGAGA
TACTGGTAAAATTGCAGAAGCAACTATGTGTTACACAGGGGATATTCATGATCCATTGCGTAGTAAATATGATTTAAATT
ACTATAAAAATTTAGCAAAAGAATTAGAAGCATCAGGAGCTCACATTTTAGGTATTAAAGATATGGCGGGCTTACTAAAA
CCAAACGCAGCATATGATTTAGTTTCAGCATTAAAAGAGACAGTATCGATTCCGATTCACCTGCACACACACGATACGAG
TGGAAATGGTATATTAACGTATACGAAAGCAATTGAAGCGGGTGTTGATATTGTCGATGTAGCAGTAAGTTCTATGGCTG
GTCAAACGTCACAACCAAGTGCGAACACGCTATACTATGCGTTAGGCGGAAACGAAAGACAGCCAGATGTTAATATAGAT
TCATTAGAAAAACTATCTCATTACTGGGAAGATGTACGTAAATACTATGCACCGTTTGAAAGTGGTATGAATGCTCCTCA
TACAGAGGTATATATGCACGAAATGCCAGGCGGACAGTATAGTAATTTACAACAACAAGCGAAAGCGGTTGGCTTAGGAG
ATCGTTTTGATGAAGTGAAAGTAATGTACCGCCGTGTGAATGACATGTTTGGTGATATTGTTAAAGTAACGCCATCATCT
AAAGTTGTCGGTGATATGGCATTATTCATGGTTCAAAATCACTTAACAGAACAAGATGTTTTAGAGCGTGGACATTCTAT
GGACTTCCCAGGATCTGTTGTTGAAATGTTCTCTGGAGACTTAGGACAACCATATGGTGGTTTCCCGAAAAAGTTACAAG
AAATTATTTTAAAAGGGAAAGAACCATTAACAGTAAGACCGGGTGAATTATTAGAGCCAGTAGATTTCGACGCGTTAAAA
GAAGAGCTATTCCATAAGCTTGGACGCGAAGTGACGATGTTTGATGTAGTTGCATATGCATTATATCCAAAAGTATTTAT
GGATTACGAAAAAGTTGCTGAGCTTTATGGAAATGTATCTGTGCTTGATACACCGACATTCTTCTATGGTATGAGACTTG
GTGAAGAAATCGATGTGGAAATTGAACAAGGTAAAACATTGATGGTTAAACTAGTATCAATCGCAGAGCCTCAGCCAGAT
GGAAATCGTGTTCTTTATCTGGAATTTAACGGTCAACCACGTGAGATTGTTGTGAAAGACGAAAGTGTGAAAGCAACAGT
TGCACAACGCGTGAAAGGAAACCGTGAAAATCCAAACCACATTAGCGCAACAATGCCAGGAACGGTTATTAAAGTAGTTG
TAAAAGAAGGCGATGAAGTGAAAAAAGGCGATTCTATGGCAATTACAGAAGCGATGAAAATGGAAACGACAGTTCAAGCG
CCGTTCAATGGTAAAGTGAAAAAAGTATATGTTAATGATGGAGATGCAATTCAAACGGGTGACTTACTCATTGAATTAGA
TCACTAA

Upstream 100 bases:

>100_bases
TTCTAAGTATAATATAATGTAGAAAGTGAAGAACTTCACGCTCTTTAGGGTGTGTATATATTTTATCTCTAGAGTGGTAG
GAAAGTAGAGGGGGAAAATC

Downstream 100 bases:

>100_bases
AATAAAAAAAGAGTTGTGGAAACACAGCTCTTTTTTATTGCGAAAAAATACCTTGCCAATTCGGCAAGGTATTTTCATTT
ATTTTGTTTGTTTAGAAGTT

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1148; Mature: 1147

Protein sequence:

>1148_residues
MTKLQRIQKVLVANRGEIAIRVFRACSELGLKTVAIYSKEDSGSYHRYKADESYLVGEGKKPIDAYLDIEGIIEIAKSNH
VDAIHPGYGFLSENIQFAKRCEEEGIIFIGPKSKHLDMFGDKVKARTQAQLAQIPVIPGSDGPVDSLEEVKEFAEKYDYP
IIIKASLGGGGRGMRIVRNSEELRESYNRAKSEAKAAFGNDEVYVEKFVEKPKHIEVQILADEEGNVVHLYERDCSVQRR
HQKVVEIAPSVSLSDDLRQRICDAAVKLTKNVNYLNAGTVEFLVKDDNFYFIEVNPRVQVEHTITEMITGVDIVQSQILI
ADGHALHSKLVGVPKQEEVVVHGFAIQSRVTTEDPLNNFMPDTGKIMAYRSGGGFGVRLDTGNSFQGAVITPYYDSLLVK
VTTWALTFEQAAAKMERNLKEFRIRGIKTNIPFLENVVKHKNFLSGEYDTSFIDASPELFLFPKRKDRGTKMLNYIGTVT
VNGFPGVGKKEKPIFPDARIPNVLHSEPIQNGTKQILDEHGADGLVKWVQDQKRVLLTDTTFRDAHQSLLATRIRTKDLH
QIAEPTARMLPNLFSAEMWGGATFDVAYRFLKEDPWERLLDLREKMPNVLFQMLLRSSNAVGYKNYPDNLIQKFVECSAQ
AGIDVFRIFDSLNWVEGMRVAIDAVRDTGKIAEATMCYTGDIHDPLRSKYDLNYYKNLAKELEASGAHILGIKDMAGLLK
PNAAYDLVSALKETVSIPIHLHTHDTSGNGILTYTKAIEAGVDIVDVAVSSMAGQTSQPSANTLYYALGGNERQPDVNID
SLEKLSHYWEDVRKYYAPFESGMNAPHTEVYMHEMPGGQYSNLQQQAKAVGLGDRFDEVKVMYRRVNDMFGDIVKVTPSS
KVVGDMALFMVQNHLTEQDVLERGHSMDFPGSVVEMFSGDLGQPYGGFPKKLQEIILKGKEPLTVRPGELLEPVDFDALK
EELFHKLGREVTMFDVVAYALYPKVFMDYEKVAELYGNVSVLDTPTFFYGMRLGEEIDVEIEQGKTLMVKLVSIAEPQPD
GNRVLYLEFNGQPREIVVKDESVKATVAQRVKGNRENPNHISATMPGTVIKVVVKEGDEVKKGDSMAITEAMKMETTVQA
PFNGKVKKVYVNDGDAIQTGDLLIELDH

Sequences:

>Translated_1148_residues
MTKLQRIQKVLVANRGEIAIRVFRACSELGLKTVAIYSKEDSGSYHRYKADESYLVGEGKKPIDAYLDIEGIIEIAKSNH
VDAIHPGYGFLSENIQFAKRCEEEGIIFIGPKSKHLDMFGDKVKARTQAQLAQIPVIPGSDGPVDSLEEVKEFAEKYDYP
IIIKASLGGGGRGMRIVRNSEELRESYNRAKSEAKAAFGNDEVYVEKFVEKPKHIEVQILADEEGNVVHLYERDCSVQRR
HQKVVEIAPSVSLSDDLRQRICDAAVKLTKNVNYLNAGTVEFLVKDDNFYFIEVNPRVQVEHTITEMITGVDIVQSQILI
ADGHALHSKLVGVPKQEEVVVHGFAIQSRVTTEDPLNNFMPDTGKIMAYRSGGGFGVRLDTGNSFQGAVITPYYDSLLVK
VTTWALTFEQAAAKMERNLKEFRIRGIKTNIPFLENVVKHKNFLSGEYDTSFIDASPELFLFPKRKDRGTKMLNYIGTVT
VNGFPGVGKKEKPIFPDARIPNVLHSEPIQNGTKQILDEHGADGLVKWVQDQKRVLLTDTTFRDAHQSLLATRIRTKDLH
QIAEPTARMLPNLFSAEMWGGATFDVAYRFLKEDPWERLLDLREKMPNVLFQMLLRSSNAVGYKNYPDNLIQKFVECSAQ
AGIDVFRIFDSLNWVEGMRVAIDAVRDTGKIAEATMCYTGDIHDPLRSKYDLNYYKNLAKELEASGAHILGIKDMAGLLK
PNAAYDLVSALKETVSIPIHLHTHDTSGNGILTYTKAIEAGVDIVDVAVSSMAGQTSQPSANTLYYALGGNERQPDVNID
SLEKLSHYWEDVRKYYAPFESGMNAPHTEVYMHEMPGGQYSNLQQQAKAVGLGDRFDEVKVMYRRVNDMFGDIVKVTPSS
KVVGDMALFMVQNHLTEQDVLERGHSMDFPGSVVEMFSGDLGQPYGGFPKKLQEIILKGKEPLTVRPGELLEPVDFDALK
EELFHKLGREVTMFDVVAYALYPKVFMDYEKVAELYGNVSVLDTPTFFYGMRLGEEIDVEIEQGKTLMVKLVSIAEPQPD
GNRVLYLEFNGQPREIVVKDESVKATVAQRVKGNRENPNHISATMPGTVIKVVVKEGDEVKKGDSMAITEAMKMETTVQA
PFNGKVKKVYVNDGDAIQTGDLLIELDH
>Mature_1147_residues
TKLQRIQKVLVANRGEIAIRVFRACSELGLKTVAIYSKEDSGSYHRYKADESYLVGEGKKPIDAYLDIEGIIEIAKSNHV
DAIHPGYGFLSENIQFAKRCEEEGIIFIGPKSKHLDMFGDKVKARTQAQLAQIPVIPGSDGPVDSLEEVKEFAEKYDYPI
IIKASLGGGGRGMRIVRNSEELRESYNRAKSEAKAAFGNDEVYVEKFVEKPKHIEVQILADEEGNVVHLYERDCSVQRRH
QKVVEIAPSVSLSDDLRQRICDAAVKLTKNVNYLNAGTVEFLVKDDNFYFIEVNPRVQVEHTITEMITGVDIVQSQILIA
DGHALHSKLVGVPKQEEVVVHGFAIQSRVTTEDPLNNFMPDTGKIMAYRSGGGFGVRLDTGNSFQGAVITPYYDSLLVKV
TTWALTFEQAAAKMERNLKEFRIRGIKTNIPFLENVVKHKNFLSGEYDTSFIDASPELFLFPKRKDRGTKMLNYIGTVTV
NGFPGVGKKEKPIFPDARIPNVLHSEPIQNGTKQILDEHGADGLVKWVQDQKRVLLTDTTFRDAHQSLLATRIRTKDLHQ
IAEPTARMLPNLFSAEMWGGATFDVAYRFLKEDPWERLLDLREKMPNVLFQMLLRSSNAVGYKNYPDNLIQKFVECSAQA
GIDVFRIFDSLNWVEGMRVAIDAVRDTGKIAEATMCYTGDIHDPLRSKYDLNYYKNLAKELEASGAHILGIKDMAGLLKP
NAAYDLVSALKETVSIPIHLHTHDTSGNGILTYTKAIEAGVDIVDVAVSSMAGQTSQPSANTLYYALGGNERQPDVNIDS
LEKLSHYWEDVRKYYAPFESGMNAPHTEVYMHEMPGGQYSNLQQQAKAVGLGDRFDEVKVMYRRVNDMFGDIVKVTPSSK
VVGDMALFMVQNHLTEQDVLERGHSMDFPGSVVEMFSGDLGQPYGGFPKKLQEIILKGKEPLTVRPGELLEPVDFDALKE
ELFHKLGREVTMFDVVAYALYPKVFMDYEKVAELYGNVSVLDTPTFFYGMRLGEEIDVEIEQGKTLMVKLVSIAEPQPDG
NRVLYLEFNGQPREIVVKDESVKATVAQRVKGNRENPNHISATMPGTVIKVVVKEGDEVKKGDSMAITEAMKMETTVQAP
FNGKVKKVYVNDGDAIQTGDLLIELDH

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1146, Percent_Identity=50.6980802792321, Blast_Score=1136, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1146, Percent_Identity=50.6980802792321, Blast_Score=1136, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1146, Percent_Identity=50.6980802792321, Blast_Score=1136, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=464, Percent_Identity=43.3189655172414, Blast_Score=395, Evalue=1e-109,
Organism=Homo sapiens, GI189095269, Length=464, Percent_Identity=42.4568965517241, Blast_Score=366, Evalue=1e-101,
Organism=Homo sapiens, GI65506442, Length=456, Percent_Identity=42.9824561403509, Blast_Score=364, Evalue=1e-100,
Organism=Homo sapiens, GI295821183, Length=456, Percent_Identity=42.9824561403509, Blast_Score=364, Evalue=1e-100,
Organism=Homo sapiens, GI134142062, Length=509, Percent_Identity=31.6306483300589, Blast_Score=241, Evalue=3e-63,
Organism=Homo sapiens, GI38679960, Length=508, Percent_Identity=32.0866141732283, Blast_Score=240, Evalue=5e-63,
Organism=Homo sapiens, GI38679974, Length=508, Percent_Identity=32.0866141732283, Blast_Score=240, Evalue=5e-63,
Organism=Homo sapiens, GI38679977, Length=508, Percent_Identity=32.0866141732283, Blast_Score=240, Evalue=5e-63,
Organism=Homo sapiens, GI38679967, Length=508, Percent_Identity=32.0866141732283, Blast_Score=240, Evalue=5e-63,
Organism=Homo sapiens, GI38679971, Length=508, Percent_Identity=32.0866141732283, Blast_Score=240, Evalue=6e-63,
Organism=Escherichia coli, GI1789654, Length=449, Percent_Identity=46.3251670378619, Blast_Score=390, Evalue=1e-109,
Organism=Escherichia coli, GI1786216, Length=365, Percent_Identity=23.013698630137, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562816, Length=1153, Percent_Identity=50.4770164787511, Blast_Score=1136, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17567343, Length=470, Percent_Identity=43.1914893617021, Blast_Score=363, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI71987519, Length=462, Percent_Identity=42.8571428571429, Blast_Score=350, Evalue=4e-96,
Organism=Caenorhabditis elegans, GI71997168, Length=438, Percent_Identity=30.8219178082192, Blast_Score=205, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI71997163, Length=438, Percent_Identity=30.8219178082192, Blast_Score=204, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI133931226, Length=499, Percent_Identity=29.6593186372746, Blast_Score=201, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1156, Percent_Identity=49.3079584775086, Blast_Score=1097, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1156, Percent_Identity=49.5674740484429, Blast_Score=1091, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=448, Percent_Identity=38.1696428571429, Blast_Score=304, Evalue=5e-83,
Organism=Saccharomyces cerevisiae, GI6323863, Length=437, Percent_Identity=34.324942791762, Blast_Score=231, Evalue=4e-61,
Organism=Saccharomyces cerevisiae, GI6324343, Length=512, Percent_Identity=30.078125, Blast_Score=224, Evalue=6e-59,
Organism=Drosophila melanogaster, GI24652212, Length=1145, Percent_Identity=51.703056768559, Blast_Score=1157, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1145, Percent_Identity=51.703056768559, Blast_Score=1157, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1145, Percent_Identity=51.703056768559, Blast_Score=1157, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1145, Percent_Identity=51.703056768559, Blast_Score=1157, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1145, Percent_Identity=51.703056768559, Blast_Score=1157, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1160, Percent_Identity=51.0344827586207, Blast_Score=1150, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1160, Percent_Identity=51.0344827586207, Blast_Score=1150, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1160, Percent_Identity=51.0344827586207, Blast_Score=1150, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1160, Percent_Identity=51.0344827586207, Blast_Score=1150, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1160, Percent_Identity=51.0344827586207, Blast_Score=1150, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=510, Percent_Identity=40.1960784313725, Blast_Score=369, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24651759, Length=467, Percent_Identity=39.4004282655246, Blast_Score=327, Evalue=4e-89,
Organism=Drosophila melanogaster, GI161076407, Length=504, Percent_Identity=31.3492063492063, Blast_Score=238, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24586460, Length=504, Percent_Identity=31.3492063492063, Blast_Score=238, Evalue=2e-62,
Organism=Drosophila melanogaster, GI161076409, Length=504, Percent_Identity=31.3492063492063, Blast_Score=238, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24586458, Length=504, Percent_Identity=31.3492063492063, Blast_Score=238, Evalue=3e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 128491; Mature: 128360

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLQRIQKVLVANRGEIAIRVFRACSELGLKTVAIYSKEDSGSYHRYKADESYLVGEGK
CCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEECCCCEEECCCC
KPIDAYLDIEGIIEIAKSNHVDAIHPGYGFLSENIQFAKRCEEEGIIFIGPKSKHLDMFG
CCHHHHCCHHHHHHHHHCCCCCEECCCCCHHHHCHHHHHHHCCCCEEEECCCCCCHHHHH
DKVKARTQAQLAQIPVIPGSDGPVDSLEEVKEFAEKYDYPIIIKASLGGGGRGMRIVRNS
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECH
EELRESYNRAKSEAKAAFGNDEVYVEKFVEKPKHIEVQILADEEGNVVHLYERDCSVQRR
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCHHHHH
HQKVVEIAPSVSLSDDLRQRICDAAVKLTKNVNYLNAGTVEFLVKDDNFYFIEVNPRVQV
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEECCCEEEEEEECCCEEEEEECCCEEE
EHTITEMITGVDIVQSQILIADGHALHSKLVGVPKQEEVVVHGFAIQSRVTTEDPLNNFM
HHHHHHHHHHHHHHHCEEEEECCHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCHHHCC
PDTGKIMAYRSGGGFGVRLDTGNSFQGAVITPYYDSLLVKVTTWALTFEQAAAKMERNLK
CCCCCEEEEECCCCEEEEEECCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHCHH
EFRIRGIKTNIPFLENVVKHKNFLSGEYDTSFIDASPELFLFPKRKDRGTKMLNYIGTVT
HHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEECCCCCEEEEECCCCCHHHHHHHHEEEE
VNGFPGVGKKEKPIFPDARIPNVLHSEPIQNGTKQILDEHGADGLVKWVQDQKRVLLTDT
ECCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHCCCCHHHHHHHCCCCEEEEEC
TFRDAHQSLLATRIRTKDLHQIAEPTARMLPNLFSAEMWGGATFDVAYRFLKEDPWERLL
CHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHH
DLREKMPNVLFQMLLRSSNAVGYKNYPDNLIQKFVECSAQAGIDVFRIFDSLNWVEGMRV
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHH
AIDAVRDTGKIAEATMCYTGDIHDPLRSKYDLNYYKNLAKELEASGAHILGIKDMAGLLK
HHHHHHCCCCHHHEEEEEECCCCHHHHHCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHC
PNAAYDLVSALKETVSIPIHLHTHDTSGNGILTYTKAIEAGVDIVDVAVSSMAGQTSQPS
CCHHHHHHHHHHHHHEEEEEEEECCCCCCEEEEEHHHHHCCCHHHHHHHHHHCCCCCCCC
ANTLYYALGGNERQPDVNIDSLEKLSHYWEDVRKYYAPFESGMNAPHTEVYMHEMPGGQY
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCH
SNLQQQAKAVGLGDRFDEVKVMYRRVNDMFGDIVKVTPSSKVVGDMALFMVQNHLTEQDV
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHCCCHHHH
LERGHSMDFPGSVVEMFSGDLGQPYGGFPKKLQEIILKGKEPLTVRPGELLEPVDFDALK
HHCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCHHHHH
EELFHKLGREVTMFDVVAYALYPKVFMDYEKVAELYGNVSVLDTPTFFYGMRLGEEIDVE
HHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCEEEECCHHHHHHHCCCEEEEE
IEQGKTLMVKLVSIAEPQPDGNRVLYLEFNGQPREIVVKDESVKATVAQRVKGNRENPNH
ECCCCEEEEEEEHHCCCCCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHCCCCCCCCE
ISATMPGTVIKVVVKEGDEVKKGDSMAITEAMKMETTVQAPFNGKVKKVYVNDGDAIQTG
EEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHEEEECCCCCCEEEEEECCCCEEEEC
DLLIELDH
CEEEEECC
>Mature Secondary Structure 
TKLQRIQKVLVANRGEIAIRVFRACSELGLKTVAIYSKEDSGSYHRYKADESYLVGEGK
CHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEECCCCEEECCCC
KPIDAYLDIEGIIEIAKSNHVDAIHPGYGFLSENIQFAKRCEEEGIIFIGPKSKHLDMFG
CCHHHHCCHHHHHHHHHCCCCCEECCCCCHHHHCHHHHHHHCCCCEEEECCCCCCHHHHH
DKVKARTQAQLAQIPVIPGSDGPVDSLEEVKEFAEKYDYPIIIKASLGGGGRGMRIVRNS
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECH
EELRESYNRAKSEAKAAFGNDEVYVEKFVEKPKHIEVQILADEEGNVVHLYERDCSVQRR
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCHHHHH
HQKVVEIAPSVSLSDDLRQRICDAAVKLTKNVNYLNAGTVEFLVKDDNFYFIEVNPRVQV
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEECCCEEEEEEECCCEEEEEECCCEEE
EHTITEMITGVDIVQSQILIADGHALHSKLVGVPKQEEVVVHGFAIQSRVTTEDPLNNFM
HHHHHHHHHHHHHHHCEEEEECCHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCHHHCC
PDTGKIMAYRSGGGFGVRLDTGNSFQGAVITPYYDSLLVKVTTWALTFEQAAAKMERNLK
CCCCCEEEEECCCCEEEEEECCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHCHH
EFRIRGIKTNIPFLENVVKHKNFLSGEYDTSFIDASPELFLFPKRKDRGTKMLNYIGTVT
HHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEECCCCCEEEEECCCCCHHHHHHHHEEEE
VNGFPGVGKKEKPIFPDARIPNVLHSEPIQNGTKQILDEHGADGLVKWVQDQKRVLLTDT
ECCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHCCCCHHHHHHHCCCCEEEEEC
TFRDAHQSLLATRIRTKDLHQIAEPTARMLPNLFSAEMWGGATFDVAYRFLKEDPWERLL
CHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHH
DLREKMPNVLFQMLLRSSNAVGYKNYPDNLIQKFVECSAQAGIDVFRIFDSLNWVEGMRV
HHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHH
AIDAVRDTGKIAEATMCYTGDIHDPLRSKYDLNYYKNLAKELEASGAHILGIKDMAGLLK
HHHHHHCCCCHHHEEEEEECCCCHHHHHCCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHC
PNAAYDLVSALKETVSIPIHLHTHDTSGNGILTYTKAIEAGVDIVDVAVSSMAGQTSQPS
CCHHHHHHHHHHHHHEEEEEEEECCCCCCEEEEEHHHHHCCCHHHHHHHHHHCCCCCCCC
ANTLYYALGGNERQPDVNIDSLEKLSHYWEDVRKYYAPFESGMNAPHTEVYMHEMPGGQY
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCH
SNLQQQAKAVGLGDRFDEVKVMYRRVNDMFGDIVKVTPSSKVVGDMALFMVQNHLTEQDV
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHCCCHHHH
LERGHSMDFPGSVVEMFSGDLGQPYGGFPKKLQEIILKGKEPLTVRPGELLEPVDFDALK
HHCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCEECCCCCCCCCCHHHHH
EELFHKLGREVTMFDVVAYALYPKVFMDYEKVAELYGNVSVLDTPTFFYGMRLGEEIDVE
HHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCEEEECCHHHHHHHCCCEEEEE
IEQGKTLMVKLVSIAEPQPDGNRVLYLEFNGQPREIVVKDESVKATVAQRVKGNRENPNH
ECCCCEEEEEEEHHCCCCCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHCCCCCCCCE
ISATMPGTVIKVVVKEGDEVKKGDSMAITEAMKMETTVQAPFNGKVKKVYVNDGDAIQTG
EEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHEEEECCCCCCEEEEEECCCCEEEEC
DLLIELDH
CEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]