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The map label for this gene is yqkF [H]

Identifier: 52141396

GI number: 52141396

Start: 3980416

End: 3981330

Strand: Direct

Name: yqkF [H]

Synonym: BCZK3852

Alternate gene names: 52141396

Gene position: 3980416-3981330 (Clockwise)

Preceding gene: 52141398

Following gene: 52141394

Centisome position: 75.09

GC content: 34.97

Gene sequence:

>915_bases
ATGAAAAAACGTCAATTAGGAAACTCAGATTTATTTGTGACAGAAATGGGACTTGGCTGTATGTCTCTCGGTACATCTGA
AACAGAAGCTATGCGTATTATCGATGAAGCAATCGATTTAGGAATCAATTTTTTTGATACAGCAGATTTATATGATTATG
GATTAAACGAAGAATTTGTTGGAAAATCCTTAAAAGGAAAACGAGACCAAATTATTCTTACAACAAAGGTTGGAAATCGA
TGGACAGAAGAAAAAAACGGTTGGTCTTGGGACCCTTCTAAAAATTACATAAAGGCTGAAGTGAAGGAAAGTTTACGTAG
ACTTCAAACTGATTATATTGATCTTTATCAACTTCACGGCGGAACGATTGAAGATCCTATAGATGAAGTAATTGAAGCCT
TTGAAGAATTAAAAAAAGAAGGTATCATTCGCCATTACGGTATTTCTTCTATACGTCCAAATGTCATTCGTGAGTATGCA
AAACGTTCAAATATCGTTAGTGTACTAATGGAATATAGCCTTTTAAATCGTCGCCCTGAAGAATGGTTCCCGCTTATTAA
TGAACATCAAATTAGCGTCATTGCCCGCGGACCACTTGCGAAAGGAATATTAACTGATAACAATGCAAGAAAGATAGAAA
GAGTAAAAGAAAAAGATTACCTTTCTTATTCTTACGATGAATTATATGCGACGCTTGCGAATGTAAAAGAAATAATTGGA
GAAAACTCCTTAACTGGAACAGCTATTCAATATTGCTTACATAACGACACTGTAGCAGCTGTAATACCTGGTGCAAGCTC
TATTCAACAATTACGAGAAAATGTACAAGCCAGTAAACAAACACAGTTAACAACAGAAGAATATATACAGCTTCAGCAAA
TCGCTAAATGTGATACGTACGCTTTACATCGTTAA

Upstream 100 bases:

>100_bases
AAGAGTATACAACTGTACAAGAGTGGATTACAGCAACTAAAAAGTAAACGTTTGTCAACCTCTTTTCCCTTGCGTACAAT
AAGGAGAAGGAGGTTGACTT

Downstream 100 bases:

>100_bases
AAAGACGCTACCATACTGGTAGCGTCTTTTTATAACGTATCATATTTATCAGGATTCGTTCCTACATGTAAATTACGATT
TAACGTATTAATTTGAGTCA

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MKKRQLGNSDLFVTEMGLGCMSLGTSETEAMRIIDEAIDLGINFFDTADLYDYGLNEEFVGKSLKGKRDQIILTTKVGNR
WTEEKNGWSWDPSKNYIKAEVKESLRRLQTDYIDLYQLHGGTIEDPIDEVIEAFEELKKEGIIRHYGISSIRPNVIREYA
KRSNIVSVLMEYSLLNRRPEEWFPLINEHQISVIARGPLAKGILTDNNARKIERVKEKDYLSYSYDELYATLANVKEIIG
ENSLTGTAIQYCLHNDTVAAVIPGASSIQQLRENVQASKQTQLTTEEYIQLQQIAKCDTYALHR

Sequences:

>Translated_304_residues
MKKRQLGNSDLFVTEMGLGCMSLGTSETEAMRIIDEAIDLGINFFDTADLYDYGLNEEFVGKSLKGKRDQIILTTKVGNR
WTEEKNGWSWDPSKNYIKAEVKESLRRLQTDYIDLYQLHGGTIEDPIDEVIEAFEELKKEGIIRHYGISSIRPNVIREYA
KRSNIVSVLMEYSLLNRRPEEWFPLINEHQISVIARGPLAKGILTDNNARKIERVKEKDYLSYSYDELYATLANVKEIIG
ENSLTGTAIQYCLHNDTVAAVIPGASSIQQLRENVQASKQTQLTTEEYIQLQQIAKCDTYALHR
>Mature_304_residues
MKKRQLGNSDLFVTEMGLGCMSLGTSETEAMRIIDEAIDLGINFFDTADLYDYGLNEEFVGKSLKGKRDQIILTTKVGNR
WTEEKNGWSWDPSKNYIKAEVKESLRRLQTDYIDLYQLHGGTIEDPIDEVIEAFEELKKEGIIRHYGISSIRPNVIREYA
KRSNIVSVLMEYSLLNRRPEEWFPLINEHQISVIARGPLAKGILTDNNARKIERVKEKDYLSYSYDELYATLANVKEIIG
ENSLTGTAIQYCLHNDTVAAVIPGASSIQQLRENVQASKQTQLTTEEYIQLQQIAKCDTYALHR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=306, Percent_Identity=29.7385620915033, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI4504825, Length=303, Percent_Identity=29.7029702970297, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI27436964, Length=306, Percent_Identity=27.4509803921569, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI27436966, Length=306, Percent_Identity=27.1241830065359, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI27436962, Length=306, Percent_Identity=27.1241830065359, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI27436971, Length=321, Percent_Identity=27.1028037383178, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI223718702, Length=300, Percent_Identity=25.3333333333333, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI87081735, Length=330, Percent_Identity=31.2121212121212, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1788070, Length=314, Percent_Identity=29.9363057324841, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789199, Length=344, Percent_Identity=26.1627906976744, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789375, Length=321, Percent_Identity=28.3489096573209, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787674, Length=283, Percent_Identity=25.4416961130742, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788081, Length=295, Percent_Identity=26.7796610169492, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI87082198, Length=215, Percent_Identity=28.3720930232558, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI48994888, Length=296, Percent_Identity=23.9864864864865, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1786400, Length=200, Percent_Identity=30.5, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI212645785, Length=305, Percent_Identity=26.8852459016393, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6325169, Length=337, Percent_Identity=27.299703264095, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6319958, Length=296, Percent_Identity=25.6756756756757, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323998, Length=321, Percent_Identity=23.6760124610592, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646155, Length=295, Percent_Identity=27.1186440677966, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24646159, Length=294, Percent_Identity=26.1904761904762, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24640980, Length=338, Percent_Identity=25.4437869822485, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45549126, Length=338, Percent_Identity=25.4437869822485, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34753; Mature: 34753

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRQLGNSDLFVTEMGLGCMSLGTSETEAMRIIDEAIDLGINFFDTADLYDYGLNEEFV
CCCCCCCCCCEEEEECCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHHH
GKSLKGKRDQIILTTKVGNRWTEEKNGWSWDPSKNYIKAEVKESLRRLQTDYIDLYQLHG
CCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
GTIEDPIDEVIEAFEELKKEGIIRHYGISSIRPNVIREYAKRSNIVSVLMEYSLLNRRPE
CCCCCHHHHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCH
EWFPLINEHQISVIARGPLAKGILTDNNARKIERVKEKDYLSYSYDELYATLANVKEIIG
HHCCCCCCCEEEEEECCCCCCCEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
ENSLTGTAIQYCLHNDTVAAVIPGASSIQQLRENVQASKQTQLTTEEYIQLQQIAKCDTY
CCCCCHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ALHR
HCCC
>Mature Secondary Structure
MKKRQLGNSDLFVTEMGLGCMSLGTSETEAMRIIDEAIDLGINFFDTADLYDYGLNEEFV
CCCCCCCCCCEEEEECCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHHH
GKSLKGKRDQIILTTKVGNRWTEEKNGWSWDPSKNYIKAEVKESLRRLQTDYIDLYQLHG
CCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
GTIEDPIDEVIEAFEELKKEGIIRHYGISSIRPNVIREYAKRSNIVSVLMEYSLLNRRPE
CCCCCHHHHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCH
EWFPLINEHQISVIARGPLAKGILTDNNARKIERVKEKDYLSYSYDELYATLANVKEIIG
HHCCCCCCCEEEEEECCCCCCCEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHC
ENSLTGTAIQYCLHNDTVAAVIPGASSIQQLRENVQASKQTQLTTEEYIQLQQIAKCDTY
CCCCCHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ALHR
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]