Click here to switch to the map view.

The map label for this gene is ackA [H]

Identifier: 52141333

GI number: 52141333

Start: 4038365

End: 4039468

Strand: Reverse

Name: ackA [H]

Synonym: BCZK3916

Alternate gene names: 52141333

Gene position: 4039468-4038365 (Counterclockwise)

Preceding gene: 52141331

Following gene: 52141335

Centisome position: 76.2

GC content: 38.13

Gene sequence:

>1104_bases
GTGTCTGTAAATCGAATTCTTGTTATTAATCCGGGTAGTACATCCACAAAAATTGGTGTTTTTGATAATGAAAGACCCGT
TTTAGAAGAAACTATTCGTCATGACGAAGAACAGATTGGAAAATATAAGCGAATTATCGACCAATATGAGTTTCGTAAAG
AAACGATCTTAGAAGTTCTACATTCTCACGGTATTAACATTTCAAAATTAAACGCAGTTTGTGGCCGTGGGGGATTACTT
CGTCCAATCGAAGGCGGAACATACACAGTAAACGATGCGATGTTAGAAGATTTAAAAAATGGTTTTAGTGGTCATCACGC
TTCAAACCTTGGGGGCATTTTAGCATATGAAATAGCTTCTGGATTAAATATTCCGGCATTCATTGTAGACCCTGTCGTTG
TAGATGAAATGGAGCCTATTGCTCGTATAAGTGGTATTGCTGGTATGGAACGTAAAAGTATTTTCCATGCATTAAATCAA
AAAGCAGTTGCTCGTAAAGTGGCTGAAGAATTAAACCACAAATATGAGGATTTAAATTTATTAGTTACACATATGGGCGG
CGGTATTACAGTTGGTGCTCATAAAAAAGGAAAAGTTATTGATGTGAATAATGGCTTAAACGGAGAAGGACCATTTAGCC
CAGAGCGTGCTGGTACAGTACCAGTAGGACAACTAGTTGAAATGTGCTTCTCTGGTGAGTATTATCGAGATGAAATGATT
AAAAAACTTGTCGGACAAGGTGGACTTGTAAGTCTTATCGGTACAAATGATGCGATTAAAGTAGAGCAAATGGTTGAAAA
AGGTGATCCTGAAGCAACTCTTATTTATAAAGCTATGGCATATCAAGTTGCAAAAGAGATTGGCGGAGCTAGCGCTGTAC
TTCACGGGAAAATCGATGCAATCGTATTAACTGGTGGACTTGCTTACAGTAAAATCCTTGTTGATGAAATAAAAGAACGA
GTAGACTGGATTGCAGATGTTATCGTACATCCAGGAGAAGATGAATTACAAGCATTAGCAGAAGGGGCACTTCGTGTACT
ACGTGAAGAAGAAGCTCCAAAAGAATATATTGTACGTGAAAAAGAAACGGTAGCTAGGGGTTGA

Upstream 100 bases:

>100_bases
TAGCCGTCGCTAATCATTCATATATTACTTTGACAAAAGGTGTGGTTACCTCTTATGAGGTTTCCACCTCCTTTTGAATT
TATTAGTGGAGGTAGCAACA

Downstream 100 bases:

>100_bases
GATAATGGCAAAAGAATATGATTTAGTCATCGTTGGCGGCGGTACTGGTGGATATGTTGCTGCTATTCGTGCATCACAAC
TAGGGTTAAAAACTGCACTT

Product: butyrate kinase

Products: NA

Alternate protein names: BK; Branched-chain carboxylic acid kinase [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSVNRILVINPGSTSTKIGVFDNERPVLEETIRHDEEQIGKYKRIIDQYEFRKETILEVLHSHGINISKLNAVCGRGGLL
RPIEGGTYTVNDAMLEDLKNGFSGHHASNLGGILAYEIASGLNIPAFIVDPVVVDEMEPIARISGIAGMERKSIFHALNQ
KAVARKVAEELNHKYEDLNLLVTHMGGGITVGAHKKGKVIDVNNGLNGEGPFSPERAGTVPVGQLVEMCFSGEYYRDEMI
KKLVGQGGLVSLIGTNDAIKVEQMVEKGDPEATLIYKAMAYQVAKEIGGASAVLHGKIDAIVLTGGLAYSKILVDEIKER
VDWIADVIVHPGEDELQALAEGALRVLREEEAPKEYIVREKETVARG

Sequences:

>Translated_367_residues
MSVNRILVINPGSTSTKIGVFDNERPVLEETIRHDEEQIGKYKRIIDQYEFRKETILEVLHSHGINISKLNAVCGRGGLL
RPIEGGTYTVNDAMLEDLKNGFSGHHASNLGGILAYEIASGLNIPAFIVDPVVVDEMEPIARISGIAGMERKSIFHALNQ
KAVARKVAEELNHKYEDLNLLVTHMGGGITVGAHKKGKVIDVNNGLNGEGPFSPERAGTVPVGQLVEMCFSGEYYRDEMI
KKLVGQGGLVSLIGTNDAIKVEQMVEKGDPEATLIYKAMAYQVAKEIGGASAVLHGKIDAIVLTGGLAYSKILVDEIKER
VDWIADVIVHPGEDELQALAEGALRVLREEEAPKEYIVREKETVARG
>Mature_366_residues
SVNRILVINPGSTSTKIGVFDNERPVLEETIRHDEEQIGKYKRIIDQYEFRKETILEVLHSHGINISKLNAVCGRGGLLR
PIEGGTYTVNDAMLEDLKNGFSGHHASNLGGILAYEIASGLNIPAFIVDPVVVDEMEPIARISGIAGMERKSIFHALNQK
AVARKVAEELNHKYEDLNLLVTHMGGGITVGAHKKGKVIDVNNGLNGEGPFSPERAGTVPVGQLVEMCFSGEYYRDEMIK
KLVGQGGLVSLIGTNDAIKVEQMVEKGDPEATLIYKAMAYQVAKEIGGASAVLHGKIDAIVLTGGLAYSKILVDEIKERV
DWIADVIVHPGEDELQALAEGALRVLREEEAPKEYIVREKETVARG

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG3426

COG function: function code C; Butyrate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=222, Percent_Identity=24.7747747747748, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788633, Length=170, Percent_Identity=28.2352941176471, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR011245 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.7 [H]

Molecular weight: Translated: 39983; Mature: 39852

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVNRILVINPGSTSTKIGVFDNERPVLEETIRHDEEQIGKYKRIIDQYEFRKETILEVL
CCCCEEEEECCCCCCCEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
HSHGINISKLNAVCGRGGLLRPIEGGTYTVNDAMLEDLKNGFSGHHASNLGGILAYEIAS
HHCCCCHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCCCHHHHHHHC
GLNIPAFIVDPVVVDEMEPIARISGIAGMERKSIFHALNQKAVARKVAEELNHKYEDLNL
CCCCCHHEECCHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHE
LVTHMGGGITVGAHKKGKVIDVNNGLNGEGPFSPERAGTVPVGQLVEMCFSGEYYRDEMI
EEEECCCCEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHH
KKLVGQGGLVSLIGTNDAIKVEQMVEKGDPEATLIYKAMAYQVAKEIGGASAVLHGKIDA
HHHHCCCCEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCEE
IVLTGGLAYSKILVDEIKERVDWIADVIVHPGEDELQALAEGALRVLREEEAPKEYIVRE
EEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCC
KETVARG
HHHHCCC
>Mature Secondary Structure 
SVNRILVINPGSTSTKIGVFDNERPVLEETIRHDEEQIGKYKRIIDQYEFRKETILEVL
CCCEEEEECCCCCCCEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
HSHGINISKLNAVCGRGGLLRPIEGGTYTVNDAMLEDLKNGFSGHHASNLGGILAYEIAS
HHCCCCHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCCCHHHHHHHC
GLNIPAFIVDPVVVDEMEPIARISGIAGMERKSIFHALNQKAVARKVAEELNHKYEDLNL
CCCCCHHEECCHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHE
LVTHMGGGITVGAHKKGKVIDVNNGLNGEGPFSPERAGTVPVGQLVEMCFSGEYYRDEMI
EEEECCCCEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHH
KKLVGQGGLVSLIGTNDAIKVEQMVEKGDPEATLIYKAMAYQVAKEIGGASAVLHGKIDA
HHHHCCCCEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCEE
IVLTGGLAYSKILVDEIKERVDWIADVIVHPGEDELQALAEGALRVLREEEAPKEYIVRE
EEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCC
KETVARG
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA