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The map label for this gene is xseA [H]

Identifier: 52141317

GI number: 52141317

Start: 4059100

End: 4060458

Strand: Reverse

Name: xseA [H]

Synonym: BCZK3933

Alternate gene names: 52141317

Gene position: 4060458-4059100 (Counterclockwise)

Preceding gene: 52141315

Following gene: 52141316

Centisome position: 76.6

GC content: 37.6

Gene sequence:

>1359_bases
ATGGAGAAACAATATTTAACCGTTACAGCGTTAACACGCTATATAAAAACAAAAATAGAATATGATCCGCATTTACAGTC
TGTTTGGTTAAAAGGTGAAATTTCCAACTTTAAAAATCATAGCCGTGGCCACATGTATTTTACATTGAAAGATGAAAATG
CAAGAATCGCAGCGGTTATGTTTGCGGGGCATAATCGTAATATTAAATTCAGACCTGAAAATGGGATGAAGGTACTCGTG
AAGGGGAAAATCTCTGTTTACGAGGCGAGTGGTTCTTATCAAATTTATATTCAAGACATGCAACCTGACGGAATTGGAAA
CCTACATTTAGCTTACGAACAATTAAAGGTTCGTTTAGAGGAAGAAGGATTGTTTTCTCAAGTTTATAAAAAAACAATCC
CTCCTTATGCGAAAACAATAGGTGTGATTACGTCACCAACAGGGGCAGCGATTCGTGATATTATAACAACGATTAAACGT
CGTTATCCAATTGGAAATGTTATTGTGTTTCCAGTACTTGTACAGGGGGAGTCAGCAGCTCCCTCAATTGTACAAGCGAT
TCGTACAGCGAATGAAATGGAAGAGATAGATGTCCTAATCGTTGGGCGTGGTGGAGGTTCTATTGAAGAATTGTGGGCGT
TTAACGAAGAAATGGTTGCAAGAGCTATTTTCAAGAGTGAAATCCCTATTATTTCAGCAGTAGGCCATGAAACAGACTTT
ACAATTGCGGATTTTGTTGCCGATTTAAGAGCGCCAACGCCAACTGCAGCGGCTGAGCTGGCAGCGCCTAATATTATAGA
GTTACAAGAAAAGGTATTACAAAGAACTTTAAGATTGCAAAGAGCAATGAGAGAGTTAGTACATAAAAAAGAAGAAAAAC
TACAAGTATTGCAAAAATCTTATGCGTTCCGTTATCCAAGACAAGTATATGAGCAAAAAGAAGAGCAATTGGATAGAGCG
TTAGAACAGCTTGTTTTAGCGAAAGAGCGCTATATTGATAAAAAGGTAAATCAGTTAAAACAGCTTTCATTTTATTTAGA
GAAGCACCACCCATCTCAAAAAATTATGCAAACGAAGGTAGCAGTTGAAACATTACAAAAGCAATTGCAACGTGAAATGC
AAACATTACTCCAAACGAAAGAATTTGCCTTTGTAAGAGCTGCTCAAAAACTTGAAGCGCTAAGTCCGCTTAAAGTAATG
ATGAGAGGGTACGGGCTTGTATATGATGAAGAGAAGCAAGTGTTAAAAAGTGTGAAAGATGTCAGCCTTGGAGATGCTGT
TTCAGTTCAATTACAAGATGGAATACTAGATTGTAGCGTATCAGGCATAGAGGAGCGTGAATTGAATAATGGAAAATAA

Upstream 100 bases:

>100_bases
GTCCAATGACAATCACGATGCTTCTTCATAATACTGTTGAATCGGCTAAGCGTGCAGGTGTCGTTTGTAAATAATTTGAG
TCGGCTATGAGGAGAGAGAA

Downstream 100 bases:

>100_bases
ATTAAGCTTTGAAGAGGCAATTTCGCAACTTGAGCATCTCGTTTCTAAGCTAGAGCAAGGTGACGTACCTTTAGAAGAAG
CAATTTCTTATTTTAAAGAG

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MEKQYLTVTALTRYIKTKIEYDPHLQSVWLKGEISNFKNHSRGHMYFTLKDENARIAAVMFAGHNRNIKFRPENGMKVLV
KGKISVYEASGSYQIYIQDMQPDGIGNLHLAYEQLKVRLEEEGLFSQVYKKTIPPYAKTIGVITSPTGAAIRDIITTIKR
RYPIGNVIVFPVLVQGESAAPSIVQAIRTANEMEEIDVLIVGRGGGSIEELWAFNEEMVARAIFKSEIPIISAVGHETDF
TIADFVADLRAPTPTAAAELAAPNIIELQEKVLQRTLRLQRAMRELVHKKEEKLQVLQKSYAFRYPRQVYEQKEEQLDRA
LEQLVLAKERYIDKKVNQLKQLSFYLEKHHPSQKIMQTKVAVETLQKQLQREMQTLLQTKEFAFVRAAQKLEALSPLKVM
MRGYGLVYDEEKQVLKSVKDVSLGDAVSVQLQDGILDCSVSGIEERELNNGK

Sequences:

>Translated_452_residues
MEKQYLTVTALTRYIKTKIEYDPHLQSVWLKGEISNFKNHSRGHMYFTLKDENARIAAVMFAGHNRNIKFRPENGMKVLV
KGKISVYEASGSYQIYIQDMQPDGIGNLHLAYEQLKVRLEEEGLFSQVYKKTIPPYAKTIGVITSPTGAAIRDIITTIKR
RYPIGNVIVFPVLVQGESAAPSIVQAIRTANEMEEIDVLIVGRGGGSIEELWAFNEEMVARAIFKSEIPIISAVGHETDF
TIADFVADLRAPTPTAAAELAAPNIIELQEKVLQRTLRLQRAMRELVHKKEEKLQVLQKSYAFRYPRQVYEQKEEQLDRA
LEQLVLAKERYIDKKVNQLKQLSFYLEKHHPSQKIMQTKVAVETLQKQLQREMQTLLQTKEFAFVRAAQKLEALSPLKVM
MRGYGLVYDEEKQVLKSVKDVSLGDAVSVQLQDGILDCSVSGIEERELNNGK
>Mature_452_residues
MEKQYLTVTALTRYIKTKIEYDPHLQSVWLKGEISNFKNHSRGHMYFTLKDENARIAAVMFAGHNRNIKFRPENGMKVLV
KGKISVYEASGSYQIYIQDMQPDGIGNLHLAYEQLKVRLEEEGLFSQVYKKTIPPYAKTIGVITSPTGAAIRDIITTIKR
RYPIGNVIVFPVLVQGESAAPSIVQAIRTANEMEEIDVLIVGRGGGSIEELWAFNEEMVARAIFKSEIPIISAVGHETDF
TIADFVADLRAPTPTAAAELAAPNIIELQEKVLQRTLRLQRAMRELVHKKEEKLQVLQKSYAFRYPRQVYEQKEEQLDRA
LEQLVLAKERYIDKKVNQLKQLSFYLEKHHPSQKIMQTKVAVETLQKQLQREMQTLLQTKEFAFVRAAQKLEALSPLKVM
MRGYGLVYDEEKQVLKSVKDVSLGDAVSVQLQDGILDCSVSGIEERELNNGK

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=439, Percent_Identity=42.5968109339408, Blast_Score=359, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 51455; Mature: 51455

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKQYLTVTALTRYIKTKIEYDPHLQSVWLKGEISNFKNHSRGHMYFTLKDENARIAAVM
CCCCEEHHHHHHHHHHHHCCCCCCHHHEEEEEEHHHCCCCCCCEEEEEEECCCCEEEEEE
FAGHNRNIKFRPENGMKVLVKGKISVYEASGSYQIYIQDMQPDGIGNLHLAYEQLKVRLE
EECCCCCEEECCCCCCEEEEEEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHH
EEGLFSQVYKKTIPPYAKTIGVITSPTGAAIRDIITTIKRRYPIGNVIVFPVLVQGESAA
HCHHHHHHHHHHCCCHHHHCCCEECCCHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCC
PSIVQAIRTANEMEEIDVLIVGRGGGSIEELWAFNEEMVARAIFKSEIPIISAVGHETDF
HHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHCCHHHHHHHHHHHCCCEEEECCCCCCC
TIADFVADLRAPTPTAAAELAAPNIIELQEKVLQRTLRLQRAMRELVHKKEEKLQVLQKS
HHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YAFRYPRQVYEQKEEQLDRALEQLVLAKERYIDKKVNQLKQLSFYLEKHHPSQKIMQTKV
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AVETLQKQLQREMQTLLQTKEFAFVRAAQKLEALSPLKVMMRGYGLVYDEEKQVLKSVKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHC
VSLGDAVSVQLQDGILDCSVSGIEERELNNGK
CCCCCEEEEEEECCCEECCCCCCHHHCCCCCC
>Mature Secondary Structure
MEKQYLTVTALTRYIKTKIEYDPHLQSVWLKGEISNFKNHSRGHMYFTLKDENARIAAVM
CCCCEEHHHHHHHHHHHHCCCCCCHHHEEEEEEHHHCCCCCCCEEEEEEECCCCEEEEEE
FAGHNRNIKFRPENGMKVLVKGKISVYEASGSYQIYIQDMQPDGIGNLHLAYEQLKVRLE
EECCCCCEEECCCCCCEEEEEEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHH
EEGLFSQVYKKTIPPYAKTIGVITSPTGAAIRDIITTIKRRYPIGNVIVFPVLVQGESAA
HCHHHHHHHHHHCCCHHHHCCCEECCCHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCC
PSIVQAIRTANEMEEIDVLIVGRGGGSIEELWAFNEEMVARAIFKSEIPIISAVGHETDF
HHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHCCHHHHHHHHHHHCCCEEEECCCCCCC
TIADFVADLRAPTPTAAAELAAPNIIELQEKVLQRTLRLQRAMRELVHKKEEKLQVLQKS
HHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YAFRYPRQVYEQKEEQLDRALEQLVLAKERYIDKKVNQLKQLSFYLEKHHPSQKIMQTKV
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AVETLQKQLQREMQTLLQTKEFAFVRAAQKLEALSPLKVMMRGYGLVYDEEKQVLKSVKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHC
VSLGDAVSVQLQDGILDCSVSGIEERELNNGK
CCCCCEEEEEEECCCEECCCCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA