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The map label for this gene is yqgN [H]

Identifier: 52141234

GI number: 52141234

Start: 4123933

End: 4124511

Strand: Reverse

Name: yqgN [H]

Synonym: BCZK4016

Alternate gene names: 52141234

Gene position: 4124511-4123933 (Counterclockwise)

Preceding gene: 52141232

Following gene: 52141233

Centisome position: 77.81

GC content: 35.06

Gene sequence:

>579_bases
GTGAGAGAAGAGAAACTACGTTTACGTAAACAAATAATAGAGCACATGAATTCTTTATCAAAAGAACGGTATACAACTTT
ATCAGAGCAAATAGCATTTTCGTTGTATGAGCAAAAAGAGTGGGCTGAAGCTAAAACAATTGGAATCACTCTCTCGATGG
AAAATGAAGTGAATACATATCCTATTATCGAAAAAGCTTGGAAAGAAGGAAAGAGAGTTGTTGTTCCGAAGTGTAATAAA
GAAACAAGAACGATGTCCTTTAGGCAAATTAGTAATTTTGATCAATTAGAAACAGTGTATATGAATTTACGTGAGCCAAT
TCCAGCACTTACGGAAGAAGTGAATGCAGATGAAATTGATCTTCAAATCGTACCAGGCGTAGCTTATACAGAGCGAGGAG
AACGGATTGGATATGGCGGTGGCTATTATGATCGTTATCTCGTGCATTATAAAGGGAAAACGCTATCATTAGCTTATAGT
TTTCAAATGGTAGAACATATTCCAGTAGAGCCGTTTGATAAAAATGTAGAAAAAATTATTACAGAAAAAGGAACAATGGT
TAAAAATGGGCTTGTATAG

Upstream 100 bases:

>100_bases
TAGGAATATTTTCCTACTGTTTCTTTTTTTATTCGATTCCTCTCTTAAAAATGATACACTATCATCGTAGAGCAAAGTAT
CACTGTGAGGGGGAAAATGT

Downstream 100 bases:

>100_bases
ACAAATAAAAATTGACGAGACTTTTTCTTCTTGATTATAATAAAATATGTGAACGTTTTCTTATTATAATTTTTTTATAG
TAAGTGAGCATAGAGGGTGA

Product: 5-formyltetrahydrofolate cyclo-ligase

Products: ADP; phosphate; 5,10-methenyltetrahydrofolate

Alternate protein names: NA

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MREEKLRLRKQIIEHMNSLSKERYTTLSEQIAFSLYEQKEWAEAKTIGITLSMENEVNTYPIIEKAWKEGKRVVVPKCNK
ETRTMSFRQISNFDQLETVYMNLREPIPALTEEVNADEIDLQIVPGVAYTERGERIGYGGGYYDRYLVHYKGKTLSLAYS
FQMVEHIPVEPFDKNVEKIITEKGTMVKNGLV

Sequences:

>Translated_192_residues
MREEKLRLRKQIIEHMNSLSKERYTTLSEQIAFSLYEQKEWAEAKTIGITLSMENEVNTYPIIEKAWKEGKRVVVPKCNK
ETRTMSFRQISNFDQLETVYMNLREPIPALTEEVNADEIDLQIVPGVAYTERGERIGYGGGYYDRYLVHYKGKTLSLAYS
FQMVEHIPVEPFDKNVEKIITEKGTMVKNGLV
>Mature_192_residues
MREEKLRLRKQIIEHMNSLSKERYTTLSEQIAFSLYEQKEWAEAKTIGITLSMENEVNTYPIIEKAWKEGKRVVVPKCNK
ETRTMSFRQISNFDQLETVYMNLREPIPALTEEVNADEIDLQIVPGVAYTERGERIGYGGGYYDRYLVHYKGKTLSLAYS
FQMVEHIPVEPFDKNVEKIITEKGTMVKNGLV

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Homo sapiens, GI5453746, Length=192, Percent_Identity=26.5625, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1789278, Length=168, Percent_Identity=30.3571428571429, Blast_Score=91, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17510857, Length=199, Percent_Identity=29.1457286432161, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321031, Length=204, Percent_Identity=26.4705882352941, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI161077430, Length=191, Percent_Identity=27.7486910994764, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: 6.3.3.2

Molecular weight: Translated: 22365; Mature: 22365

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREEKLRLRKQIIEHMNSLSKERYTTLSEQIAFSLYEQKEWAEAKTIGITLSMENEVNTY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCC
PIIEKAWKEGKRVVVPKCNKETRTMSFRQISNFDQLETVYMNLREPIPALTEEVNADEID
HHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHCCCCEEE
LQIVPGVAYTERGERIGYGGGYYDRYLVHYKGKTLSLAYSFQMVEHIPVEPFDKNVEKII
EEEECCCCCCCCCCCCCCCCCHHHEEEEEECCCEEEEEEEEHHHHHCCCCCCCCHHHHHH
TEKGTMVKNGLV
HCCCCCCCCCCC
>Mature Secondary Structure
MREEKLRLRKQIIEHMNSLSKERYTTLSEQIAFSLYEQKEWAEAKTIGITLSMENEVNTY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCC
PIIEKAWKEGKRVVVPKCNKETRTMSFRQISNFDQLETVYMNLREPIPALTEEVNADEID
HHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHCCCCEEE
LQIVPGVAYTERGERIGYGGGYYDRYLVHYKGKTLSLAYSFQMVEHIPVEPFDKNVEKII
EEEECCCCCCCCCCCCCCCCCHHHEEEEEECCCEEEEEEEEHHHHHCCCCCCCCHHHHHH
TEKGTMVKNGLV
HCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 5-formyltetrahydrofolate

Specific reaction: ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]