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The map label for this gene is hrcA [H]

Identifier: 52141186

GI number: 52141186

Start: 4172225

End: 4173241

Strand: Reverse

Name: hrcA [H]

Synonym: BCZK4063

Alternate gene names: 52141186

Gene position: 4173241-4172225 (Counterclockwise)

Preceding gene: 52141187

Following gene: 52141188

Centisome position: 78.73

GC content: 36.18

Gene sequence:

>1017_bases
ATGCTTACGGAACGTCAGCTCTTAATTTTACAAACAATTATTGATGACTTTATTGGATCAGCGCAACCTGTTGGGTCAAG
AACGTTGGCTAAGAAAGATGCAATTACATTTAGTTCAGCTACTATTCGAAATGAAATGGCTGATTTAGAGGAACTAGGAT
TTATTGAGAAAACCCACAGTTCTTCAGGACGTGTTCCTTCTGAAAAAGGATACCGATTTTATGTAGACCATCTTTTAGCG
CCGCAAAACTTACCAAAAGATGAAATTGTACAAATTAAAGATTTATTTGCTGAAAGAATTTTTGAAGCGGAAAAGATTGC
GCAGCAATCCGCTCAAATTTTATCAGAGCTTACAAATTATACGGCCATTGTTCTTGGACCGAAGTTAAGCACAAATAAAC
TTAAAAACGTACAAATCGTTCCGCTGGATCGTCAAACTGCAGTCGCTATTATTGTAACGGATACAGGGCATGTACAAAGC
AAAACGATTACCGTTCCGGAATCTGTTGATTTATCAGATTTAGAAAAAATGGTTAATATTTTAAATGAAAAGCTATCGGG
CGTACCAATGTCAGAACTCCATAATAAAATCTTTAAGGAGATTGTTACTGTATTGCGTGGGTATGTTCATAATTACGATA
GTGCAATAAAAATGTTAGATGGTACATTTCAAGTTCCTTTATCGGAAAAGATATACTTTGGAGGAAAAGCAAATATGCTT
TCCCAGCCAGAGTTCCATGACATTCACAAAGTAAGGTCCTTACTGACGATGATTGATAACGAAGCTGAGTTTTATGATAT
TTTGCGTCATAAACAAGTCGGTATTCAAGTGAAAATTGGTAGGGAAAACTCTGCGACGGCCATGGAAGATTGTAGTTTGA
TTTCTGCAACGTATTCGATTGGAGAAGAACAGCTTGGAACAATTGCTATTTTAGGTCCGACAAGAATGCAATACTCTCGG
GTAATTAGTTTGTTACAGTTATTTACGAGACAATTTACAGATGGACTTAAAAAGTAA

Upstream 100 bases:

>100_bases
ATTTCGTGACGTTTCCGTTGACAATTGAATGTCAATTTTGGTAAGTTATTAATAGATTTAGCACTCGAAGACAAAGAGTG
CTAACAGAGGTGATGATGAG

Downstream 100 bases:

>100_bases
ATGAGAGTAATACATTCGCTCAAGTGATGAACTTTTCATTGCTGTGTGTAATATATAATGCTTAGGTAATTGTGTTTAAC
ATGGTACCTAATACCTTTTA

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MLTERQLLILQTIIDDFIGSAQPVGSRTLAKKDAITFSSATIRNEMADLEELGFIEKTHSSSGRVPSEKGYRFYVDHLLA
PQNLPKDEIVQIKDLFAERIFEAEKIAQQSAQILSELTNYTAIVLGPKLSTNKLKNVQIVPLDRQTAVAIIVTDTGHVQS
KTITVPESVDLSDLEKMVNILNEKLSGVPMSELHNKIFKEIVTVLRGYVHNYDSAIKMLDGTFQVPLSEKIYFGGKANML
SQPEFHDIHKVRSLLTMIDNEAEFYDILRHKQVGIQVKIGRENSATAMEDCSLISATYSIGEEQLGTIAILGPTRMQYSR
VISLLQLFTRQFTDGLKK

Sequences:

>Translated_338_residues
MLTERQLLILQTIIDDFIGSAQPVGSRTLAKKDAITFSSATIRNEMADLEELGFIEKTHSSSGRVPSEKGYRFYVDHLLA
PQNLPKDEIVQIKDLFAERIFEAEKIAQQSAQILSELTNYTAIVLGPKLSTNKLKNVQIVPLDRQTAVAIIVTDTGHVQS
KTITVPESVDLSDLEKMVNILNEKLSGVPMSELHNKIFKEIVTVLRGYVHNYDSAIKMLDGTFQVPLSEKIYFGGKANML
SQPEFHDIHKVRSLLTMIDNEAEFYDILRHKQVGIQVKIGRENSATAMEDCSLISATYSIGEEQLGTIAILGPTRMQYSR
VISLLQLFTRQFTDGLKK
>Mature_338_residues
MLTERQLLILQTIIDDFIGSAQPVGSRTLAKKDAITFSSATIRNEMADLEELGFIEKTHSSSGRVPSEKGYRFYVDHLLA
PQNLPKDEIVQIKDLFAERIFEAEKIAQQSAQILSELTNYTAIVLGPKLSTNKLKNVQIVPLDRQTAVAIIVTDTGHVQS
KTITVPESVDLSDLEKMVNILNEKLSGVPMSELHNKIFKEIVTVLRGYVHNYDSAIKMLDGTFQVPLSEKIYFGGKANML
SQPEFHDIHKVRSLLTMIDNEAEFYDILRHKQVGIQVKIGRENSATAMEDCSLISATYSIGEEQLGTIAILGPTRMQYSR
VISLLQLFTRQFTDGLKK

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR023120
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 37872; Mature: 37872

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTERQLLILQTIIDDFIGSAQPVGSRTLAKKDAITFSSATIRNEMADLEELGFIEKTHS
CCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCEEHHHHHHHHHHHHHHHCCHHHCCC
SSGRVPSEKGYRFYVDHLLAPQNLPKDEIVQIKDLFAERIFEAEKIAQQSAQILSELTNY
CCCCCCCCCCCEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TAIVLGPKLSTNKLKNVQIVPLDRQTAVAIIVTDTGHVQSKTITVPESVDLSDLEKMVNI
EEEEECCCCCCCCCCCEEEEECCCCCEEEEEEECCCCCCCCEEECCCCCCHHHHHHHHHH
LNEKLSGVPMSELHNKIFKEIVTVLRGYVHNYDSAIKMLDGTFQVPLSEKIYFGGKANML
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEEECCCCCCC
SQPEFHDIHKVRSLLTMIDNEAEFYDILRHKQVGIQVKIGRENSATAMEDCSLISATYSI
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHC
GEEQLGTIAILGPTRMQYSRVISLLQLFTRQFTDGLKK
CHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLTERQLLILQTIIDDFIGSAQPVGSRTLAKKDAITFSSATIRNEMADLEELGFIEKTHS
CCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCEEHHHHHHHHHHHHHHHCCHHHCCC
SSGRVPSEKGYRFYVDHLLAPQNLPKDEIVQIKDLFAERIFEAEKIAQQSAQILSELTNY
CCCCCCCCCCCEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TAIVLGPKLSTNKLKNVQIVPLDRQTAVAIIVTDTGHVQSKTITVPESVDLSDLEKMVNI
EEEEECCCCCCCCCCCEEEEECCCCCEEEEEEECCCCCCCCEEECCCCCCHHHHHHHHHH
LNEKLSGVPMSELHNKIFKEIVTVLRGYVHNYDSAIKMLDGTFQVPLSEKIYFGGKANML
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCEEEECCCCCCC
SQPEFHDIHKVRSLLTMIDNEAEFYDILRHKQVGIQVKIGRENSATAMEDCSLISATYSI
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHC
GEEQLGTIAILGPTRMQYSRVISLLQLFTRQFTDGLKK
CHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA