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The map label for this gene is dtD [H]

Identifier: 52141099

GI number: 52141099

Start: 4255825

End: 4256265

Strand: Reverse

Name: dtD [H]

Synonym: BCZK4150

Alternate gene names: 52141099

Gene position: 4256265-4255825 (Counterclockwise)

Preceding gene: 52141100

Following gene: 52141101

Centisome position: 80.29

GC content: 39.0

Gene sequence:

>441_bases
ATGAGAGTTGTTTTACAACGATCAAAAGAAGCGTCTGTCACAGTAGACGGTGAGATCGTAGGACAAATTCCGTTCGGTTT
AACATTACTAGTTGGCATTACGCATGAAGATACAGAAAAAGATGCAACTTACATTGCAGAAAAAATTGCGAACTTACGTA
TTTTTGAAGATGAGAGTGGAAAGATGAACCATTCTGTACTTGATGTAGAAGGACAAGTTCTATCCATTTCGCAATTCACA
TTATACGGAGATTGCCGCAAGGGAAGACGTCCAAACTTTATGGATGCTGCCAAACCTGACTATGCAGAGCGTTTATATGA
TTTCTTTAATGAAGAAGTACGTAAGCAAGGATTGCATGTAGAAACAGGGAAGTTCGGAGCAATGATGGATGTTTCTTTAA
TCAATGATGGTCCGGTGACCCTTATTGTGGAAAGTAAATAG

Upstream 100 bases:

>100_bases
GTAACTTACAGCACTTGAAAAAAGTAGTAGAACGCATTAAACGTGTTCCAGAAATTTATGCAGTACGACGCATGATGCAT
TAATAGGGAGTGTAGAAAAG

Downstream 100 bases:

>100_bases
TGTTGAAAGAAGAGAGGGGATGAGCCCCTCTCTTCTTTTATGGTTTTTAATGGTATATTTTGTTAATTATTGTTATGATA
GTTAAGAAAATAAACGATAT

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MRVVLQRSKEASVTVDGEIVGQIPFGLTLLVGITHEDTEKDATYIAEKIANLRIFEDESGKMNHSVLDVEGQVLSISQFT
LYGDCRKGRRPNFMDAAKPDYAERLYDFFNEEVRKQGLHVETGKFGAMMDVSLINDGPVTLIVESK

Sequences:

>Translated_146_residues
MRVVLQRSKEASVTVDGEIVGQIPFGLTLLVGITHEDTEKDATYIAEKIANLRIFEDESGKMNHSVLDVEGQVLSISQFT
LYGDCRKGRRPNFMDAAKPDYAERLYDFFNEEVRKQGLHVETGKFGAMMDVSLINDGPVTLIVESK
>Mature_146_residues
MRVVLQRSKEASVTVDGEIVGQIPFGLTLLVGITHEDTEKDATYIAEKIANLRIFEDESGKMNHSVLDVEGQVLSISQFT
LYGDCRKGRRPNFMDAAKPDYAERLYDFFNEEVRKQGLHVETGKFGAMMDVSLINDGPVTLIVESK

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine [H]

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family [H]

Homologues:

Organism=Homo sapiens, GI30795227, Length=149, Percent_Identity=46.3087248322148, Blast_Score=119, Evalue=1e-27,
Organism=Escherichia coli, GI1790320, Length=144, Percent_Identity=47.2222222222222, Blast_Score=143, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI115533292, Length=149, Percent_Identity=46.9798657718121, Blast_Score=126, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=41.2162162162162, Blast_Score=115, Evalue=2e-27,
Organism=Drosophila melanogaster, GI281361569, Length=147, Percent_Identity=44.8979591836735, Blast_Score=116, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003732 [H]

Pfam domain/function: PF02580 Tyr_Deacylase [H]

EC number: NA

Molecular weight: Translated: 16342; Mature: 16342

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVVLQRSKEASVTVDGEIVGQIPFGLTLLVGITHEDTEKDATYIAEKIANLRIFEDESG
CCEEEECCCCCEEEECCEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHCEEEEECCCC
KMNHSVLDVEGQVLSISQFTLYGDCRKGRRPNFMDAAKPDYAERLYDFFNEEVRKQGLHV
CCCCEEEECCCCEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
ETGKFGAMMDVSLINDGPVTLIVESK
ECCCCCCEEEEEEECCCCEEEEEECC
>Mature Secondary Structure
MRVVLQRSKEASVTVDGEIVGQIPFGLTLLVGITHEDTEKDATYIAEKIANLRIFEDESG
CCEEEECCCCCEEEECCEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHCEEEEECCCC
KMNHSVLDVEGQVLSISQFTLYGDCRKGRRPNFMDAAKPDYAERLYDFFNEEVRKQGLHV
CCCCEEEECCCCEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
ETGKFGAMMDVSLINDGPVTLIVESK
ECCCCCCEEEEEEECCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA