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The map label for this gene is hemA [H]

Identifier: 52141036

GI number: 52141036

Start: 4318024

End: 4319358

Strand: Reverse

Name: hemA [H]

Synonym: BCZK4210

Alternate gene names: 52141036

Gene position: 4319358-4318024 (Counterclockwise)

Preceding gene: 52141039

Following gene: 52141041

Centisome position: 81.48

GC content: 37.6

Gene sequence:

>1335_bases
GTGCATATTCTTGTTGTTAGTGTAAATTATCGAACAGCCCCTGTAGAATTTCGTGAGAAACTCACATTTCAGGCAGCAGA
GCTAGAGCGAGCAATGACGACATTACAAAATCAAAAGAGCGTGTTAGAGAATGTCATTGTATCAACTTGTAATCGCACTG
AGATTTACGCTGTTGTCGATCAATTACACACGGGACGGTATTATATTAAGAAGTTTTTAGCTGATTGGTTTCAGCTTGAA
ATAGAAGAAGTCGCACCATATTTAACTATTTTTGAACAAGATGGTGCAATAGATCATTTATTCCGCGTAACGTGCGGTTT
AGATTCTATGGTAGTTGGAGAGACGCAAATTTTAGGTCAAATAAAAGATAGCTTTTTAGAAGCGCAACAAGTAAAAGCAA
CAGGGACAATTTTTAATGAATTGTTTAAGCAAGTCATTACATTAGCGAAACGTGCTCACTCAGAAACGACAATTGGTGAA
AGTGCGATGTCTGTTAGTTATGCTGCTGTTGAGCTAGGGAAGAAGATATTCGGCGAGTTAACAGATTGTCACGTGCTTAT
TCTCGGTGCTGGTAAAATGGGTGAACTTGCACTGCAGAACTTATATGGAAGCGGTGCTCGTAAAGTAACAGTCATGAATA
GAACGCTTTCAAAAGCAGAAATAATGGCTGAGAAATATATGGGACATGCAAAACCTTTAAGTGAATTACAATGTGCATTA
TTAGAAGCTGATATTTTAATTAGTTCAACTGGTGCATCGGATTATGTCATTACGAAAGAGATGATGACAAAAGTAGAGAA
AATGCGCTCTGGTCGTCCATTATTTATGGTTGATATTGCAGTGCCGCGTGATATTGATCCCGCGATTGATGAGCTAGAAG
GTTCTTTCTTATATGACATTGATGATTTGCAAGGAGTAGTGGAAGCGAACCGTGCTGAACGTTTAAAAGAAGCAGAGAAA
ATTCAATTTATGATTGAAGAGGAAATTGTTTTATTTAAAACGTGGTTAAGTACACTTGGTGTCGTTCCGTTAATATCAGC
CCTTCGTGATAAGGCACTTGCTATCCAAAGTGAAACGATGGAAAGTCTGGAACGAAAAATACCGAATCTTAGTGATCGTG
AGAGAAAAGTAATTAGTAAGCATACGAAAAGTATTATTAATCAATTATTAAAAGACCCAATTTTAGTAGCGAAAGAAATA
GCTGCTGAAGAGGGAGCAGACGAAAAATTAGCGTTATTTGCAAAGATTTTTGATTTAGAAATGGAAGACGTAGAGAGTCG
TGCGGAAGAAGTAGAACATAAAAGAGCGTGGACACCATCCGTTCCATCTTTATAA

Upstream 100 bases:

>100_bases
AAAAATAATCAGTTGTTCACACGATTGTCAGATTCATAAGAGGAAAGTTGTATTATGATAGTAGATAAAGTGATAAAACG
GGTGAAGGGGGACATGCTGC

Downstream 100 bases:

>100_bases
TTTGGAAGGATGATCGGATGAGTTTTTTAAATAACAGTATTATTTATCATATTGCAATTATTTTATATGCTTGTAGCATT
AGTTTATATTTTATAGATTA

Product: glutamyl-tRNA reductase

Products: NA

Alternate protein names: GluTR [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MHILVVSVNYRTAPVEFREKLTFQAAELERAMTTLQNQKSVLENVIVSTCNRTEIYAVVDQLHTGRYYIKKFLADWFQLE
IEEVAPYLTIFEQDGAIDHLFRVTCGLDSMVVGETQILGQIKDSFLEAQQVKATGTIFNELFKQVITLAKRAHSETTIGE
SAMSVSYAAVELGKKIFGELTDCHVLILGAGKMGELALQNLYGSGARKVTVMNRTLSKAEIMAEKYMGHAKPLSELQCAL
LEADILISSTGASDYVITKEMMTKVEKMRSGRPLFMVDIAVPRDIDPAIDELEGSFLYDIDDLQGVVEANRAERLKEAEK
IQFMIEEEIVLFKTWLSTLGVVPLISALRDKALAIQSETMESLERKIPNLSDRERKVISKHTKSIINQLLKDPILVAKEI
AAEEGADEKLALFAKIFDLEMEDVESRAEEVEHKRAWTPSVPSL

Sequences:

>Translated_444_residues
MHILVVSVNYRTAPVEFREKLTFQAAELERAMTTLQNQKSVLENVIVSTCNRTEIYAVVDQLHTGRYYIKKFLADWFQLE
IEEVAPYLTIFEQDGAIDHLFRVTCGLDSMVVGETQILGQIKDSFLEAQQVKATGTIFNELFKQVITLAKRAHSETTIGE
SAMSVSYAAVELGKKIFGELTDCHVLILGAGKMGELALQNLYGSGARKVTVMNRTLSKAEIMAEKYMGHAKPLSELQCAL
LEADILISSTGASDYVITKEMMTKVEKMRSGRPLFMVDIAVPRDIDPAIDELEGSFLYDIDDLQGVVEANRAERLKEAEK
IQFMIEEEIVLFKTWLSTLGVVPLISALRDKALAIQSETMESLERKIPNLSDRERKVISKHTKSIINQLLKDPILVAKEI
AAEEGADEKLALFAKIFDLEMEDVESRAEEVEHKRAWTPSVPSL
>Mature_444_residues
MHILVVSVNYRTAPVEFREKLTFQAAELERAMTTLQNQKSVLENVIVSTCNRTEIYAVVDQLHTGRYYIKKFLADWFQLE
IEEVAPYLTIFEQDGAIDHLFRVTCGLDSMVVGETQILGQIKDSFLEAQQVKATGTIFNELFKQVITLAKRAHSETTIGE
SAMSVSYAAVELGKKIFGELTDCHVLILGAGKMGELALQNLYGSGARKVTVMNRTLSKAEIMAEKYMGHAKPLSELQCAL
LEADILISSTGASDYVITKEMMTKVEKMRSGRPLFMVDIAVPRDIDPAIDELEGSFLYDIDDLQGVVEANRAERLKEAEK
IQFMIEEEIVLFKTWLSTLGVVPLISALRDKALAIQSETMESLERKIPNLSDRERKVISKHTKSIINQLLKDPILVAKEI
AAEEGADEKLALFAKIFDLEMEDVESRAEEVEHKRAWTPSVPSL

Specific function: Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) [H]

COG id: COG0373

COG function: function code H; Glutamyl-tRNA reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamyl-tRNA reductase family [H]

Homologues:

Organism=Escherichia coli, GI1787461, Length=420, Percent_Identity=33.0952380952381, Blast_Score=236, Evalue=3e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000343
- InterPro:   IPR015896
- InterPro:   IPR015895
- InterPro:   IPR016040
- InterPro:   IPR018214
- InterPro:   IPR006151 [H]

Pfam domain/function: PF00745 GlutR_dimer; PF05201 GlutR_N; PF01488 Shikimate_DH [H]

EC number: =1.2.1.70 [H]

Molecular weight: Translated: 49797; Mature: 49797

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00747 GLUTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHILVVSVNYRTAPVEFREKLTFQAAELERAMTTLQNQKSVLENVIVSTCNRTEIYAVVD
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
QLHTGRYYIKKFLADWFQLEIEEVAPYLTIFEQDGAIDHLFRVTCGLDSMVVGETQILGQ
HHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHH
IKDSFLEAQQVKATGTIFNELFKQVITLAKRAHSETTIGESAMSVSYAAVELGKKIFGEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCC
TDCHVLILGAGKMGELALQNLYGSGARKVTVMNRTLSKAEIMAEKYMGHAKPLSELQCAL
CCCEEEEEECCCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LEADILISSTGASDYVITKEMMTKVEKMRSGRPLFMVDIAVPRDIDPAIDELEGSFLYDI
HHHHHEEECCCCCCCEEHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHCCCCEEEEH
DDLQGVVEANRAERLKEAEKIQFMIEEEIVLFKTWLSTLGVVPLISALRDKALAIQSETM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESLERKIPNLSDRERKVISKHTKSIINQLLKDPILVAKEIAAEEGADEKLALFAKIFDLE
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHCC
MEDVESRAEEVEHKRAWTPSVPSL
HHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MHILVVSVNYRTAPVEFREKLTFQAAELERAMTTLQNQKSVLENVIVSTCNRTEIYAVVD
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
QLHTGRYYIKKFLADWFQLEIEEVAPYLTIFEQDGAIDHLFRVTCGLDSMVVGETQILGQ
HHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHH
IKDSFLEAQQVKATGTIFNELFKQVITLAKRAHSETTIGESAMSVSYAAVELGKKIFGEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCC
TDCHVLILGAGKMGELALQNLYGSGARKVTVMNRTLSKAEIMAEKYMGHAKPLSELQCAL
CCCEEEEEECCCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LEADILISSTGASDYVITKEMMTKVEKMRSGRPLFMVDIAVPRDIDPAIDELEGSFLYDI
HHHHHEEECCCCCCCEEHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHCCCCEEEEH
DDLQGVVEANRAERLKEAEKIQFMIEEEIVLFKTWLSTLGVVPLISALRDKALAIQSETM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESLERKIPNLSDRERKVISKHTKSIINQLLKDPILVAKEIAAEEGADEKLALFAKIFDLE
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHCC
MEDVESRAEEVEHKRAWTPSVPSL
HHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA