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The map label for this gene is nrnA [H]

Identifier: 52140902

GI number: 52140902

Start: 4465847

End: 4466779

Strand: Reverse

Name: nrnA [H]

Synonym: BCZK4348

Alternate gene names: 52140902

Gene position: 4466779-4465847 (Counterclockwise)

Preceding gene: 52140901

Following gene: 52140905

Centisome position: 84.26

GC content: 37.08

Gene sequence:

>933_bases
ATGCATGAGAAAATTTTAGGAGCAATTAAAGAGTTTGATACAATTATTATTCATCGTCATGTGCGTCCGGATCCAGATGC
GTTAGGCTCACAGGGCGGTCTTAGTACCATTCTACAAGAATCGTTTCCAGAGAAAAATATTTATACGGTTGGGTACAATG
AACCGTCATTAGCATATTTACGAGTAATGGATGAGATTGAAGATAGTGTATACGAAAATGCGCTTGTTATCGTTTGTGAT
ACAGCAAACCAAGAACGTGTTGACGATCAACGCTATACAAAAGGGAAGATGTTAATCAAAATTGATCATCATCCAAATGA
GGATCCATACGGAGATATTACGTGGGTAGATACGACAGCAAGTTCTACAAGTGAAATGATTTATGAGTTTTATAATTATG
GAAAAGATAAAGGGTTACAAATAACAAAAGAAGCAGCTCGTCTTATTTTAGCGGGTATTGTTGGGGATACAGGACGTTTC
TTATTCCCGAATACAACAGCAAAAACACTTCGTTACGTAAGTGAGCTTGTTGATATGGATGTGAAATTCACGGATTTATA
CAATGAAATGTATAAGACGAAAGAAAAAATCGCTCGTTTAAACGGCTATATTTTACAAAACTTTACGATGGTAGAAGAAG
GAGCAGCTTACATTAAATTAACGAAAGAAGTATTAGAAAAATTTGATGTACTTCCTTCTGAGGCATCCGGTGTTGTTGGA
GCACTTGGTAACATTGATGGATTAAAGGCGTGGGTTCTATTTTTAGAGGAAGACGATGTGATTCGTGTTCGTCTTCGTTC
AAAAGGACCAGTTATAAATAAATTAGCAATGCAATATAACGGCGGAGGACATCCGATGGCTTCTGGTGCAAAAGCATCTT
CTTGGGAAGAAGCGGATCGTCTATTTGCTGATTTACGTGAGATTTGTAAATAA

Upstream 100 bases:

>100_bases
TAGTGTGGGGATGTTTCCGCGCGCTAATGATTAGCCCACATTCATTGGGCTTTTACTGCACGTTAAAGTGAAGAAGTTGA
ATAAAAAGGAGATTATACAT

Downstream 100 bases:

>100_bases
GAAATTATATGTTAGAACGAAAAGAAGGAGTGGCGTTAAAGCCCTCCTTCTTTATTTTTCTTTCTCTATCGTAATGCTAA
TTTCAAGCACGGTATCAAAA

Product: DHH family phosphoesterase

Products: NA

Alternate protein names: 3'(2'),5'-bisphosphate nucleotidase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; nanoRNAse [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MHEKILGAIKEFDTIIIHRHVRPDPDALGSQGGLSTILQESFPEKNIYTVGYNEPSLAYLRVMDEIEDSVYENALVIVCD
TANQERVDDQRYTKGKMLIKIDHHPNEDPYGDITWVDTTASSTSEMIYEFYNYGKDKGLQITKEAARLILAGIVGDTGRF
LFPNTTAKTLRYVSELVDMDVKFTDLYNEMYKTKEKIARLNGYILQNFTMVEEGAAYIKLTKEVLEKFDVLPSEASGVVG
ALGNIDGLKAWVLFLEEDDVIRVRLRSKGPVINKLAMQYNGGGHPMASGAKASSWEEADRLFADLREICK

Sequences:

>Translated_310_residues
MHEKILGAIKEFDTIIIHRHVRPDPDALGSQGGLSTILQESFPEKNIYTVGYNEPSLAYLRVMDEIEDSVYENALVIVCD
TANQERVDDQRYTKGKMLIKIDHHPNEDPYGDITWVDTTASSTSEMIYEFYNYGKDKGLQITKEAARLILAGIVGDTGRF
LFPNTTAKTLRYVSELVDMDVKFTDLYNEMYKTKEKIARLNGYILQNFTMVEEGAAYIKLTKEVLEKFDVLPSEASGVVG
ALGNIDGLKAWVLFLEEDDVIRVRLRSKGPVINKLAMQYNGGGHPMASGAKASSWEEADRLFADLREICK
>Mature_310_residues
MHEKILGAIKEFDTIIIHRHVRPDPDALGSQGGLSTILQESFPEKNIYTVGYNEPSLAYLRVMDEIEDSVYENALVIVCD
TANQERVDDQRYTKGKMLIKIDHHPNEDPYGDITWVDTTASSTSEMIYEFYNYGKDKGLQITKEAARLILAGIVGDTGRF
LFPNTTAKTLRYVSELVDMDVKFTDLYNEMYKTKEKIARLNGYILQNFTMVEEGAAYIKLTKEVLEKFDVLPSEASGVVG
ALGNIDGLKAWVLFLEEDDVIRVRLRSKGPVINKLAMQYNGGGHPMASGAKASSWEEADRLFADLREICK

Specific function: Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities. Degrades RNA oligonucleotides with a length of 5 nucleotides and shorter. Converts 3'(2')- phosphoadenosine 5'-phosphate (PAP) to AMP [H]

COG id: COG0618

COG function: function code R; Exopolyphosphatase-related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003156
- InterPro:   IPR001667 [H]

Pfam domain/function: PF01368 DHH; PF02272 DHHA1 [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 34923; Mature: 34923

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEKILGAIKEFDTIIIHRHVRPDPDALGSQGGLSTILQESFPEKNIYTVGYNEPSLAYL
CCHHHHHHHHHHCEEEEEECCCCCHHHCCCCCCHHHHHHHHCCCCCEEEECCCCCCHHHH
RVMDEIEDSVYENALVIVCDTANQERVDDQRYTKGKMLIKIDHHPNEDPYGDITWVDTTA
HHHHHHHHHHHCCEEEEEECCCCCHHCCHHHHCCCEEEEEECCCCCCCCCCCEEEEECCC
SSTSEMIYEFYNYGKDKGLQITKEAARLILAGIVGDTGRFLFPNTTAKTLRYVSELVDMD
CHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHCC
VKFTDLYNEMYKTKEKIARLNGYILQNFTMVEEGAAYIKLTKEVLEKFDVLPSEASGVVG
CHHHHHHHHHHHHHHHHHHHCCHHHCCEEEHHCCCHHHHHHHHHHHHHCCCCCCCCCHHH
ALGNIDGLKAWVLFLEEDDVIRVRLRSKGPVINKLAMQYNGGGHPMASGAKASSWEEADR
HHCCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHHHEECCCCCCCCCCCCCCCHHHHHH
LFADLREICK
HHHHHHHHCC
>Mature Secondary Structure
MHEKILGAIKEFDTIIIHRHVRPDPDALGSQGGLSTILQESFPEKNIYTVGYNEPSLAYL
CCHHHHHHHHHHCEEEEEECCCCCHHHCCCCCCHHHHHHHHCCCCCEEEECCCCCCHHHH
RVMDEIEDSVYENALVIVCDTANQERVDDQRYTKGKMLIKIDHHPNEDPYGDITWVDTTA
HHHHHHHHHHHCCEEEEEECCCCCHHCCHHHHCCCEEEEEECCCCCCCCCCCEEEEECCC
SSTSEMIYEFYNYGKDKGLQITKEAARLILAGIVGDTGRFLFPNTTAKTLRYVSELVDMD
CHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHCC
VKFTDLYNEMYKTKEKIARLNGYILQNFTMVEEGAAYIKLTKEVLEKFDVLPSEASGVVG
CHHHHHHHHHHHHHHHHHHHCCHHHCCEEEHHCCCHHHHHHHHHHHHHCCCCCCCCCHHH
ALGNIDGLKAWVLFLEEDDVIRVRLRSKGPVINKLAMQYNGGGHPMASGAKASSWEEADR
HHCCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHHHEECCCCCCCCCCCCCCCHHHHHH
LFADLREICK
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]