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The map label for this gene is pepQ [H]

Identifier: 52140895

GI number: 52140895

Start: 4471846

End: 4472943

Strand: Direct

Name: pepQ [H]

Synonym: BCZK4355

Alternate gene names: 52140895

Gene position: 4471846-4472943 (Clockwise)

Preceding gene: 52140900

Following gene: 52140894

Centisome position: 84.36

GC content: 38.52

Gene sequence:

>1098_bases
ATGAATGCTAGATTAGAAAATTTAATGCAATGGCTAAAAGAAAAAAACGTAGAAGCTGTGTTCTTAACTTCTACACCAAA
CGTCTTCTACATGACAAACTTCCACTGTGAACCACACGAAAGACTTCTTGGTATGTTTGTATTCCAAGAAAAAGAGCCTA
TTTTAATTTGTCCTAAAATGGAAGAAGGTCAAGCGCGTAACGCGGGATGGGCACATGAAATTATCGGATTTACTGATACT
GACAGACCATGGGATATGATTGCAAAAGCAATTAAAGACCGCGGTATCCATGCAAATGCAGTTGCAATTGAAAAAGAACA
TTTAAACGTAGAGCGCTACGAAGAATTAACAAAACTATTCCCAAATGCAGCTTTCACATCAGCTGAGGAAAAAGTTCGTG
AACTTCGTTTAATTAAAGATGAAAAAGAGCTTTCTATTTTACGCGAAGCAGCTAAAATGGCAGACTATGCTGTTGAAGTT
GGTGTAAATGCAATTAAAGAAGATCGCAGCGAACTAGAAGTATTAGCAATTATTGAACACGAATTAAAAACAAAAGGCAT
ACATAAAATGTCATTTGATACGATGGTATTAGCTGGTGCAAACTCTGCTCTTCCACACGGTATTCCAGGTGCAAACAAAA
TGAAACGCGGCGATTTCATACTATTTGATTTAGGCGTAATCATTGACGGTTATTGCTCTGACATTACACGTACAGTGGCA
TTTGGCGAGATTTCTGAAGAACAAACTCGCATTTACAACACTGTACTTGCTGGACAACTACAAGCAGTTGAAGCATGTAA
ACCAGGTATTACACTTGGCGCAATCGACAACGCTGCTCGTTCTGTTATCGCAGATGCAGGTTATGGTGACTTTTTCCCGC
ACCGCCTTGGTCACGGACTTGGAATTAGCGTACACGAATATCCAGATGTAAAAGCTGGTAACGAGTCTCCATTAAAAGAA
GGTATGGTCTTCACAATTGAACCAGGTATTTACGTACCAAACGTAGGTGGCGTTCGTATTGAAGATGATATTTATATCAC
AAAAGACGGATCAGAAATTTTAACGAAGTTCCCGAAAGAATTACAATTTGTAAAATAA

Upstream 100 bases:

>100_bases
TTTCAATTCCCTGTCTTTTCTAACATCTATTTACTTGTCATAACGCTTTCTTCCGAGTTAAAGTTATATTTGTAATTAAA
TATCTCGGGGGTGCCAATCG

Downstream 100 bases:

>100_bases
TAAAAAAGGCAGCGTGAGTGCTGCCTTTTTTATTTCTCTACTATTTCAAACTTCTCTACAATCATTTTTGCTGGATAGCT
TTCAAGCATTTGAGAAGACC

Product: Xaa-Pro dipeptidase (proline dipeptidase)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MNARLENLMQWLKEKNVEAVFLTSTPNVFYMTNFHCEPHERLLGMFVFQEKEPILICPKMEEGQARNAGWAHEIIGFTDT
DRPWDMIAKAIKDRGIHANAVAIEKEHLNVERYEELTKLFPNAAFTSAEEKVRELRLIKDEKELSILREAAKMADYAVEV
GVNAIKEDRSELEVLAIIEHELKTKGIHKMSFDTMVLAGANSALPHGIPGANKMKRGDFILFDLGVIIDGYCSDITRTVA
FGEISEEQTRIYNTVLAGQLQAVEACKPGITLGAIDNAARSVIADAGYGDFFPHRLGHGLGISVHEYPDVKAGNESPLKE
GMVFTIEPGIYVPNVGGVRIEDDIYITKDGSEILTKFPKELQFVK

Sequences:

>Translated_365_residues
MNARLENLMQWLKEKNVEAVFLTSTPNVFYMTNFHCEPHERLLGMFVFQEKEPILICPKMEEGQARNAGWAHEIIGFTDT
DRPWDMIAKAIKDRGIHANAVAIEKEHLNVERYEELTKLFPNAAFTSAEEKVRELRLIKDEKELSILREAAKMADYAVEV
GVNAIKEDRSELEVLAIIEHELKTKGIHKMSFDTMVLAGANSALPHGIPGANKMKRGDFILFDLGVIIDGYCSDITRTVA
FGEISEEQTRIYNTVLAGQLQAVEACKPGITLGAIDNAARSVIADAGYGDFFPHRLGHGLGISVHEYPDVKAGNESPLKE
GMVFTIEPGIYVPNVGGVRIEDDIYITKDGSEILTKFPKELQFVK
>Mature_365_residues
MNARLENLMQWLKEKNVEAVFLTSTPNVFYMTNFHCEPHERLLGMFVFQEKEPILICPKMEEGQARNAGWAHEIIGFTDT
DRPWDMIAKAIKDRGIHANAVAIEKEHLNVERYEELTKLFPNAAFTSAEEKVRELRLIKDEKELSILREAAKMADYAVEV
GVNAIKEDRSELEVLAIIEHELKTKGIHKMSFDTMVLAGANSALPHGIPGANKMKRGDFILFDLGVIIDGYCSDITRTVA
FGEISEEQTRIYNTVLAGQLQAVEACKPGITLGAIDNAARSVIADAGYGDFFPHRLGHGLGISVHEYPDVKAGNESPLKE
GMVFTIEPGIYVPNVGGVRIEDDIYITKDGSEILTKFPKELQFVK

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=262, Percent_Identity=31.2977099236641, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI149589008, Length=332, Percent_Identity=26.5060240963855, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI260593665, Length=332, Percent_Identity=26.5060240963855, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI40385867, Length=248, Percent_Identity=27.0161290322581, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI260593663, Length=252, Percent_Identity=27.7777777777778, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI93141226, Length=248, Percent_Identity=30.6451612903226, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI264681563, Length=166, Percent_Identity=33.1325301204819, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI164420681, Length=249, Percent_Identity=24.4979919678715, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI264681565, Length=163, Percent_Identity=31.2883435582822, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1788728, Length=374, Percent_Identity=36.096256684492, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1789275, Length=263, Percent_Identity=30.7984790874525, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1786364, Length=232, Percent_Identity=28.0172413793103, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17508215, Length=301, Percent_Identity=26.9102990033223, Blast_Score=104, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17509539, Length=232, Percent_Identity=30.1724137931034, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320922, Length=258, Percent_Identity=28.6821705426357, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6321118, Length=281, Percent_Identity=29.1814946619217, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6323273, Length=230, Percent_Identity=24.3478260869565, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19920384, Length=282, Percent_Identity=29.4326241134752, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21357079, Length=295, Percent_Identity=29.1525423728814, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21355531, Length=263, Percent_Identity=25.4752851711027, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24583427, Length=235, Percent_Identity=25.531914893617, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 40763; Mature: 40763

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNARLENLMQWLKEKNVEAVFLTSTPNVFYMTNFHCEPHERLLGMFVFQEKEPILICPKM
CCHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEECCCHHHHHHHHHEEECCCCEEEECCC
EEGQARNAGWAHEIIGFTDTDRPWDMIAKAIKDRGIHANAVAIEKEHLNVERYEELTKLF
CCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEHHHCCHHHHHHHHHHC
PNAAFTSAEEKVRELRLIKDEKELSILREAAKMADYAVEVGVNAIKEDRSELEVLAIIEH
CCCHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELKTKGIHKMSFDTMVLAGANSALPHGIPGANKMKRGDFILFDLGVIIDGYCSDITRTVA
HHHHCCCEEECCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHH
FGEISEEQTRIYNTVLAGQLQAVEACKPGITLGAIDNAARSVIADAGYGDFFPHRLGHGL
HCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHCCCCCCCCHHHHCCCC
GISVHEYPDVKAGNESPLKEGMVFTIEPGIYVPNVGGVRIEDDIYITKDGSEILTKFPKE
CCEEECCCCCCCCCCCHHHCCCEEEECCCEEECCCCCEEEECCEEEECCCHHHHHHCHHH
LQFVK
HCCCC
>Mature Secondary Structure
MNARLENLMQWLKEKNVEAVFLTSTPNVFYMTNFHCEPHERLLGMFVFQEKEPILICPKM
CCHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEECCCHHHHHHHHHEEECCCCEEEECCC
EEGQARNAGWAHEIIGFTDTDRPWDMIAKAIKDRGIHANAVAIEKEHLNVERYEELTKLF
CCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEHHHCCHHHHHHHHHHC
PNAAFTSAEEKVRELRLIKDEKELSILREAAKMADYAVEVGVNAIKEDRSELEVLAIIEH
CCCHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELKTKGIHKMSFDTMVLAGANSALPHGIPGANKMKRGDFILFDLGVIIDGYCSDITRTVA
HHHHCCCEEECCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHH
FGEISEEQTRIYNTVLAGQLQAVEACKPGITLGAIDNAARSVIADAGYGDFFPHRLGHGL
HCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHCCCCCCCCHHHHCCCC
GISVHEYPDVKAGNESPLKEGMVFTIEPGIYVPNVGGVRIEDDIYITKDGSEILTKFPKE
CCEEECCCCCCCCCCCHHHCCCEEEECCCEEECCCCCEEEECCEEEECCCHHHHHHCHHH
LQFVK
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]