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The map label for this gene is p20 [H]

Identifier: 52140737

GI number: 52140737

Start: 4610773

End: 4611297

Strand: Direct

Name: p20 [H]

Synonym: BCZK4516

Alternate gene names: 52140737

Gene position: 4610773-4611297 (Clockwise)

Preceding gene: 52140741

Following gene: 52140736

Centisome position: 86.98

GC content: 31.62

Gene sequence:

>525_bases
TTGTTTGAATCAAACCGTATCCAGTTACGAAAATTTTCCGAAGATGATATTCTAACATATTATAAATGGCATAATGATAT
AGACGTTATGAGTTCAACTACTCTCACTCTTGATAAATATTCCCTTCAAGACACAGAAAAACTTTGCCAACAATTTATTC
ATTCTTCGGACTCTAAAAGCTATATCATTGAAGAAAAAGCTACGCATCTTTCAATTGGTATTACTTCTTTAATTCATATT
GATTCGTATAATCGAAACGCTGAATGTATTATTGATATTGGTAACAAGGATTACTGGGGGCAAGGTTATGGGAAGGAAGC
TTTCACCTTATTATTGGATTATGCATTTTTAGAATTAAATTTACATCGCCTTTCTTTACGAGTATTTTCTTTTAACGATA
GAGCAATTAAATTATATAAATCGCTCGGTTTTCAACATGAAGGAACTTGTAAAGAAGCTATATTCCGCAATGGCACTTGG
CATGACATTGAACTCTTCGCTTTATTCCAACGTAATTATATATAA

Upstream 100 bases:

>100_bases
CGAATATGAGAAAGTATATTGAACTAGAAGGAGAGATTTATTGTAGCTCGTGTGTTGAAATAATGAACAAAAAATAGTAA
ATACAAAAGGGGGACTTACA

Downstream 100 bases:

>100_bases
AAAAAGCTTTGCGCTCACTGCGCAAAGCTTTTTTTCATATATTATAGACCAGCTTGCTCTTTTAAAGCTGCAGCTTTGTC
TGTACGTTCCCATGATAGAT

Product: acetyltransferase

Products: Coenzyme A; H+; N8-Acetylspermidine [C]

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MFESNRIQLRKFSEDDILTYYKWHNDIDVMSSTTLTLDKYSLQDTEKLCQQFIHSSDSKSYIIEEKATHLSIGITSLIHI
DSYNRNAECIIDIGNKDYWGQGYGKEAFTLLLDYAFLELNLHRLSLRVFSFNDRAIKLYKSLGFQHEGTCKEAIFRNGTW
HDIELFALFQRNYI

Sequences:

>Translated_174_residues
MFESNRIQLRKFSEDDILTYYKWHNDIDVMSSTTLTLDKYSLQDTEKLCQQFIHSSDSKSYIIEEKATHLSIGITSLIHI
DSYNRNAECIIDIGNKDYWGQGYGKEAFTLLLDYAFLELNLHRLSLRVFSFNDRAIKLYKSLGFQHEGTCKEAIFRNGTW
HDIELFALFQRNYI
>Mature_174_residues
MFESNRIQLRKFSEDDILTYYKWHNDIDVMSSTTLTLDKYSLQDTEKLCQQFIHSSDSKSYIIEEKATHLSIGITSLIHI
DSYNRNAECIIDIGNKDYWGQGYGKEAFTLLLDYAFLELNLHRLSLRVFSFNDRAIKLYKSLGFQHEGTCKEAIFRNGTW
HDIELFALFQRNYI

Specific function: Regulates Polyamine Concentration By Their Degradation. Acts On Spermidine, Forming N(1)- And N(8)-Acetylspermidine. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1787867, Length=177, Percent_Identity=28.8135593220339, Blast_Score=73, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181 [H]

Pfam domain/function: PF00583 Acetyltransf_1 [H]

EC number: 2.3.1.57 [C]

Molecular weight: Translated: 20515; Mature: 20515

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFESNRIQLRKFSEDDILTYYKWHNDIDVMSSTTLTLDKYSLQDTEKLCQQFIHSSDSKS
CCCCCCEEEEEECCCCEEEEEEECCCEEEECCCEEEEECCCCHHHHHHHHHHHHCCCCCE
YIIEEKATHLSIGITSLIHIDSYNRNAECIIDIGNKDYWGQGYGKEAFTLLLDYAFLELN
EEEECCCCEEEEEEEEEEEEECCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHEEE
LHRLSLRVFSFNDRAIKLYKSLGFQHEGTCKEAIFRNGTWHDIELFALFQRNYI
EEEEEEEEEECCCHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHHEEEEEHHCCC
>Mature Secondary Structure
MFESNRIQLRKFSEDDILTYYKWHNDIDVMSSTTLTLDKYSLQDTEKLCQQFIHSSDSKS
CCCCCCEEEEEECCCCEEEEEEECCCEEEECCCEEEEECCCCHHHHHHHHHHHHCCCCCE
YIIEEKATHLSIGITSLIHIDSYNRNAECIIDIGNKDYWGQGYGKEAFTLLLDYAFLELN
EEEECCCCEEEEEEEEEEEEECCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHEEE
LHRLSLRVFSFNDRAIKLYKSLGFQHEGTCKEAIFRNGTWHDIELFALFQRNYI
EEEEEEEEEECCCHHHHHHHHHCCCCCCCHHHHHHCCCCCCHHHEEEEEHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; Spermidine [C]

Specific reaction: Acetyl-CoA + Spermidine --> Coenzyme A + H+ + N8-Acetylspermidine [C]

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2838827 [H]