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The map label for this gene is yxdK [H]

Identifier: 52140666

GI number: 52140666

Start: 4672849

End: 4673871

Strand: Direct

Name: yxdK [H]

Synonym: BCZK4588

Alternate gene names: 52140666

Gene position: 4672849-4673871 (Clockwise)

Preceding gene: 52140668

Following gene: 52140665

Centisome position: 88.15

GC content: 35.29

Gene sequence:

>1023_bases
ATGAAGCTATTTTTACGTGATCATTTTGCATTTTTTCTACTGTACATATTAAACTTCGGTATCATTTTCGTTCTTTATGA
TGCAGTAGATGGATTTCAAAATAATAAATTTTACTTCGTTGTTTTAAGCTTATACTTATTTATTTGTTTCCTCGCTTATC
GTTACGTTCGTAATCGTAGAATGTACCATAGATTAAGTGAACAACCAGAAAAAATGGAAGATGCGTTTATTGAAAGAGCA
ACTGCTCCGATGCCTAACGGTGTAAATGAACTCGTGCGCACGCAGTATCGTCTCTTCCAAAAAGAACTACAATCGTATGA
AGTAAAACAACAAGAACATCAATTATTCATTAACCACTGGGTGCATCAAATGAAAACGCCCGTTTCTGTTATGCAACTTA
TGGTGCTTGAAATGGAAGATGAACATTTAATTCCGAAATTCAAAAAAGAATTAGAACGTCTAAACCAAGGGCTTGATATG
GCTTTATACATGGCAAGGTTAAATAACTTCCATGAAGACTTCCATGTTGAGACAATTTCATTAAAAGATACGGTAACGAA
AAATATTAATGGATTAAAAGAACTATTTATCCGAAACGGAGTCTTCCCTGTTTTAGAAGTTCATTCTGATTTAAAGGTTG
CTTCTGATGCGAAATGGCTAAAATTTATCATCTATCAGTTAATGACAAATGCCGTTCGTTACTCTGGTCAGCGCGGAAAG
AAAGTATTCTTATCCGCTTATCGAAACGGAAAAGATATTATTTTAGAAGTTCGTGATGAAGGTGTTGGTATTCCGCAAGA
AGATATTCGACGAGTATTCGAACCGTTTTACACTGGGAAAAATGGTCGTACATTCGGAGAATCTACTGGTATGGGACTTT
ATATCGTAAGTAAAATTTGTGATTATTTAGGTCACTCTGTCAAACTAGATTCTGAAGTTGGTAAAGGAACGACGATTAAA
ATCATCTTCCACAACGCTGCAAATAATCAATCAGAACATGCGGAGAAGGTGACCGAAGCATGA

Upstream 100 bases:

>100_bases
CGCGTCTTCGTAAAAAGTTCAATGAGCTTGGTATTGAAAATGCTATTGAAACAGTGCGCGGACTTGGGTATCGTTTTAAC
GCAACTTGGAGTGAATAAGC

Downstream 100 bases:

>100_bases
TCGTGACATATGCAAGCAAAATGTATGAGAACTCACTCTCATACATTTTTTGCAATAAAACTACTTCTATATCTTCTAAC
AGGAGGTATAATTTATGACC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MKLFLRDHFAFFLLYILNFGIIFVLYDAVDGFQNNKFYFVVLSLYLFICFLAYRYVRNRRMYHRLSEQPEKMEDAFIERA
TAPMPNGVNELVRTQYRLFQKELQSYEVKQQEHQLFINHWVHQMKTPVSVMQLMVLEMEDEHLIPKFKKELERLNQGLDM
ALYMARLNNFHEDFHVETISLKDTVTKNINGLKELFIRNGVFPVLEVHSDLKVASDAKWLKFIIYQLMTNAVRYSGQRGK
KVFLSAYRNGKDIILEVRDEGVGIPQEDIRRVFEPFYTGKNGRTFGESTGMGLYIVSKICDYLGHSVKLDSEVGKGTTIK
IIFHNAANNQSEHAEKVTEA

Sequences:

>Translated_340_residues
MKLFLRDHFAFFLLYILNFGIIFVLYDAVDGFQNNKFYFVVLSLYLFICFLAYRYVRNRRMYHRLSEQPEKMEDAFIERA
TAPMPNGVNELVRTQYRLFQKELQSYEVKQQEHQLFINHWVHQMKTPVSVMQLMVLEMEDEHLIPKFKKELERLNQGLDM
ALYMARLNNFHEDFHVETISLKDTVTKNINGLKELFIRNGVFPVLEVHSDLKVASDAKWLKFIIYQLMTNAVRYSGQRGK
KVFLSAYRNGKDIILEVRDEGVGIPQEDIRRVFEPFYTGKNGRTFGESTGMGLYIVSKICDYLGHSVKLDSEVGKGTTIK
IIFHNAANNQSEHAEKVTEA
>Mature_340_residues
MKLFLRDHFAFFLLYILNFGIIFVLYDAVDGFQNNKFYFVVLSLYLFICFLAYRYVRNRRMYHRLSEQPEKMEDAFIERA
TAPMPNGVNELVRTQYRLFQKELQSYEVKQQEHQLFINHWVHQMKTPVSVMQLMVLEMEDEHLIPKFKKELERLNQGLDM
ALYMARLNNFHEDFHVETISLKDTVTKNINGLKELFIRNGVFPVLEVHSDLKVASDAKWLKFIIYQLMTNAVRYSGQRGK
KVFLSAYRNGKDIILEVRDEGVGIPQEDIRRVFEPFYTGKNGRTFGESTGMGLYIVSKICDYLGHSVKLDSEVGKGTTIK
IIFHNAANNQSEHAEKVTEA

Specific function: Probable member of the two-component regulatory system yxdK/yxdJ. May activate yxdJ in response to the antibacterial protein LL-37 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=253, Percent_Identity=22.5296442687747, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI48994928, Length=131, Percent_Identity=30.5343511450382, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790436, Length=243, Percent_Identity=24.2798353909465, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467 [H]

Pfam domain/function: PF02518 HATPase_c [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39870; Mature: 39870

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFLRDHFAFFLLYILNFGIIFVLYDAVDGFQNNKFYFVVLSLYLFICFLAYRYVRNRR
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MYHRLSEQPEKMEDAFIERATAPMPNGVNELVRTQYRLFQKELQSYEVKQQEHQLFINHW
HHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VHQMKTPVSVMQLMVLEMEDEHLIPKFKKELERLNQGLDMALYMARLNNFHEDFHVETIS
HHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCEEEEE
LKDTVTKNINGLKELFIRNGVFPVLEVHSDLKVASDAKWLKFIIYQLMTNAVRYSGQRGK
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCC
KVFLSAYRNGKDIILEVRDEGVGIPQEDIRRVFEPFYTGKNGRTFGESTGMGLYIVSKIC
HHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
DYLGHSVKLDSEVGKGTTIKIIFHNAANNQSEHAEKVTEA
HHCCCCEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHCC
>Mature Secondary Structure
MKLFLRDHFAFFLLYILNFGIIFVLYDAVDGFQNNKFYFVVLSLYLFICFLAYRYVRNRR
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MYHRLSEQPEKMEDAFIERATAPMPNGVNELVRTQYRLFQKELQSYEVKQQEHQLFINHW
HHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VHQMKTPVSVMQLMVLEMEDEHLIPKFKKELERLNQGLDMALYMARLNNFHEDFHVETIS
HHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCEEEEE
LKDTVTKNINGLKELFIRNGVFPVLEVHSDLKVASDAKWLKFIIYQLMTNAVRYSGQRGK
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCC
KVFLSAYRNGKDIILEVRDEGVGIPQEDIRRVFEPFYTGKNGRTFGESTGMGLYIVSKIC
HHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
DYLGHSVKLDSEVGKGTTIKIIFHNAANNQSEHAEKVTEA
HHCCCCEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7952181; 9384377; 8867804 [H]