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The map label for this gene is mcpA [H]

Identifier: 52140521

GI number: 52140521

Start: 4829534

End: 4831534

Strand: Reverse

Name: mcpA [H]

Synonym: BCZK4739

Alternate gene names: 52140521

Gene position: 4831534-4829534 (Counterclockwise)

Preceding gene: 52140517

Following gene: 52140520

Centisome position: 91.15

GC content: 37.23

Gene sequence:

>2001_bases
ATGTTAAGAAGTTTACGTTTAAAAATTGCGGTAGTATTTTCGGTACTTATTTCTATGATGTTCGTAATATTGGGTACAGC
TATGTATGAATTACAGAAAGAGAAGGAAGTGCGCTCCTTAGACCAGTATTCTCAAAATACGATGGATCTTGTGACAGAGC
AACTTACAACATTTGTTCAAAGAACGGATGAAGATATGGGGTATTATGCGAACAGTGAAATGATTCGTAATATGCTTCAA
GATGGAGTTACTCCAGAAGAGGAAGCATTTTTGACGAAAGAGTTTTCGGAGTATAAAAAGAATCATCCTGGCATTTTAGA
CTTATATATTGGTACGAAAGATAAAAAAACATTAAGTGCCAATCTTGCTGAAGGTGGAAAAGTGCCAGAGGGATATGATC
CAACGACAAGACCTTGGTATAAAGACTCAGAAGGTGATGTGAAAACGGTTCACTGGGGACAACCTATGTATGAAATTGCA
ACAGGTAAGTTAAGCGTGGGAGTTTCTAAAGCAATTACAGCTCAAGATGGCTCTGTATTAGGTGTTGTGGCGATGGATGT
ATCGCTCGGAACAATTCAGAAATTACTTCATAATATTCAATACAATAACGGTGGAGAAATGTTTATTATAAATGATAAAA
ATATGGCTCTTGTTTACCCAGAAAAGATAGGGAAAGATGTTTCGAAAGAGCCACTTGTGAAGAGTTTAAATAAAGATGTA
ACAAAGTATGCTGTCACTACATTAAAAGGTGAAGATGTAGTTGCATATAGTCAGTCATTTGATTTGATGAAATGGAAGAT
AGGAATTTTTTATCCGAAAGAAACGATTGATGGACTATTAAATAGTACGAGAAATACAGTCATTATAATGGCATGTATTA
GCCTATTCGTTGGAATCGTAGCTTCATACTTGTTCTCACGAAGATTAGCAAGACCACTGCAACTATTAACGAATCACGTT
CAAAAAGTAGCAGAAGGTGATTTAACGTTGAAAATGAAAGTGACAAGTAAGGATGAAGTTGGAGAACTGACGAACCATTT
TAATCATATGGTTGAGCAAATGAATGAAATGGTAAGTAAAATTAAAAATAGTGTATCAACCGTGCAACAATCAACGAATA
ATCTACATTATTTAACGAATGAAACTGTAGCAGCTAGTAAAGAAGTGTCAGGTGCAATGGATGATGTGAGCGGAGGAGCT
TCTACGCTCGCTAATAGTGTAGATGAAGTTTCAGAACAGCTTGAGAATATGATACAGTCAGTGGAACAAATGAATAGCTC
CGTTGGTGAAATAAAAGGAGTAGCTGGCAAAGCAGAAGAGGCATCTAAGCAAGGATTGAATACGATGCGAAATTTAGTTC
GTACAAGAGAACAATCCTCTTCAATTGTTGTTCATACAGAGGAAGCATCTGGAAAGCTAGAGCAAAGGGTTGGATCGATT
CAAAATGTTGTAGAGCTTATAAAAGGTATTTCGGATCAAACGAATTTACTTGCTTTAAATGCTTCAATCGAGGCGGCACG
TGCGGGTGAACAAGGTAAAGGCTTTGCTGTTGTTGCTGAAGAGGTTCGGAAATTAGCGGAACAATCAAAAGAAGCAACAG
TAGAAATTGCGACGATGATTGGTGATGTACAAGTAGAGGTAAGACGAGTTGTAGAAGTTGTAAGTAAATTAAAAGATATT
GCGGATATACAAAATAATGTTACGACAGAAGCAGAGGCGGAGTTCCGTACAATTATGTCAGTTGTTAATACCATTAGTAC
CTCAGTGGAACAAATTGTAGAAGAGGTACATAACATCGGTCACGAGCAAGGAGAAATTACAGCGGTAATGCATACAATTG
CTGGTACGAGTCAAGAAAGTGCAGCTGTTTCGGAAGAAGTAAATGCTGCAACTGAATCACAAGTGAATCATCTAGAAAAG
GTAGCTCATACGATGGAAAGCTTGACCGAGCATATGAGAGACTTGGAAAGATTGGTTGAGCAATTTAAAATAGAGGAATA
A

Upstream 100 bases:

>100_bases
TAAGGTGAGAATTAATTTCAATTTTTTAATTTTATCTATTATACTTAATATAATGATTAATAAGATTTAAATTCAATGCG
AAGGGGATGCTTGGGGGAAG

Downstream 100 bases:

>100_bases
CAAATTAGTAAAATGATGCGTATTTCGGTAAAATAGATAATGGATATATAAGAAGCAATTATAGGAGGAAGACTACTATG
GCAATTGTTGACGTATCGAT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 666; Mature: 666

Protein sequence:

>666_residues
MLRSLRLKIAVVFSVLISMMFVILGTAMYELQKEKEVRSLDQYSQNTMDLVTEQLTTFVQRTDEDMGYYANSEMIRNMLQ
DGVTPEEEAFLTKEFSEYKKNHPGILDLYIGTKDKKTLSANLAEGGKVPEGYDPTTRPWYKDSEGDVKTVHWGQPMYEIA
TGKLSVGVSKAITAQDGSVLGVVAMDVSLGTIQKLLHNIQYNNGGEMFIINDKNMALVYPEKIGKDVSKEPLVKSLNKDV
TKYAVTTLKGEDVVAYSQSFDLMKWKIGIFYPKETIDGLLNSTRNTVIIMACISLFVGIVASYLFSRRLARPLQLLTNHV
QKVAEGDLTLKMKVTSKDEVGELTNHFNHMVEQMNEMVSKIKNSVSTVQQSTNNLHYLTNETVAASKEVSGAMDDVSGGA
STLANSVDEVSEQLENMIQSVEQMNSSVGEIKGVAGKAEEASKQGLNTMRNLVRTREQSSSIVVHTEEASGKLEQRVGSI
QNVVELIKGISDQTNLLALNASIEAARAGEQGKGFAVVAEEVRKLAEQSKEATVEIATMIGDVQVEVRRVVEVVSKLKDI
ADIQNNVTTEAEAEFRTIMSVVNTISTSVEQIVEEVHNIGHEQGEITAVMHTIAGTSQESAAVSEEVNAATESQVNHLEK
VAHTMESLTEHMRDLERLVEQFKIEE

Sequences:

>Translated_666_residues
MLRSLRLKIAVVFSVLISMMFVILGTAMYELQKEKEVRSLDQYSQNTMDLVTEQLTTFVQRTDEDMGYYANSEMIRNMLQ
DGVTPEEEAFLTKEFSEYKKNHPGILDLYIGTKDKKTLSANLAEGGKVPEGYDPTTRPWYKDSEGDVKTVHWGQPMYEIA
TGKLSVGVSKAITAQDGSVLGVVAMDVSLGTIQKLLHNIQYNNGGEMFIINDKNMALVYPEKIGKDVSKEPLVKSLNKDV
TKYAVTTLKGEDVVAYSQSFDLMKWKIGIFYPKETIDGLLNSTRNTVIIMACISLFVGIVASYLFSRRLARPLQLLTNHV
QKVAEGDLTLKMKVTSKDEVGELTNHFNHMVEQMNEMVSKIKNSVSTVQQSTNNLHYLTNETVAASKEVSGAMDDVSGGA
STLANSVDEVSEQLENMIQSVEQMNSSVGEIKGVAGKAEEASKQGLNTMRNLVRTREQSSSIVVHTEEASGKLEQRVGSI
QNVVELIKGISDQTNLLALNASIEAARAGEQGKGFAVVAEEVRKLAEQSKEATVEIATMIGDVQVEVRRVVEVVSKLKDI
ADIQNNVTTEAEAEFRTIMSVVNTISTSVEQIVEEVHNIGHEQGEITAVMHTIAGTSQESAAVSEEVNAATESQVNHLEK
VAHTMESLTEHMRDLERLVEQFKIEE
>Mature_666_residues
MLRSLRLKIAVVFSVLISMMFVILGTAMYELQKEKEVRSLDQYSQNTMDLVTEQLTTFVQRTDEDMGYYANSEMIRNMLQ
DGVTPEEEAFLTKEFSEYKKNHPGILDLYIGTKDKKTLSANLAEGGKVPEGYDPTTRPWYKDSEGDVKTVHWGQPMYEIA
TGKLSVGVSKAITAQDGSVLGVVAMDVSLGTIQKLLHNIQYNNGGEMFIINDKNMALVYPEKIGKDVSKEPLVKSLNKDV
TKYAVTTLKGEDVVAYSQSFDLMKWKIGIFYPKETIDGLLNSTRNTVIIMACISLFVGIVASYLFSRRLARPLQLLTNHV
QKVAEGDLTLKMKVTSKDEVGELTNHFNHMVEQMNEMVSKIKNSVSTVQQSTNNLHYLTNETVAASKEVSGAMDDVSGGA
STLANSVDEVSEQLENMIQSVEQMNSSVGEIKGVAGKAEEASKQGLNTMRNLVRTREQSSSIVVHTEEASGKLEQRVGSI
QNVVELIKGISDQTNLLALNASIEAARAGEQGKGFAVVAEEVRKLAEQSKEATVEIATMIGDVQVEVRRVVEVVSKLKDI
ADIQNNVTTEAEAEFRTIMSVVNTISTSVEQIVEEVHNIGHEQGEITAVMHTIAGTSQESAAVSEEVNAATESQVNHLEK
VAHTMESLTEHMRDLERLVEQFKIEE

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=305, Percent_Identity=28.8524590163934, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1787690, Length=380, Percent_Identity=27.1052631578947, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1788195, Length=240, Percent_Identity=29.1666666666667, Blast_Score=110, Evalue=4e-25,
Organism=Escherichia coli, GI1788194, Length=361, Percent_Identity=27.1468144044321, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1789453, Length=329, Percent_Identity=30.0911854103343, Blast_Score=100, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 73554; Mature: 73554

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRSLRLKIAVVFSVLISMMFVILGTAMYELQKEKEVRSLDQYSQNTMDLVTEQLTTFVQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTDEDMGYYANSEMIRNMLQDGVTPEEEAFLTKEFSEYKKNHPGILDLYIGTKDKKTLSA
HCCHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHC
NLAEGGKVPEGYDPTTRPWYKDSEGDVKTVHWGQPMYEIATGKLSVGVSKAITAQDGSVL
CHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHCCCEECCHHHHEECCCCCEE
GVVAMDVSLGTIQKLLHNIQYNNGGEMFIINDKNMALVYPEKIGKDVSKEPLVKSLNKDV
EEEEECCCHHHHHHHHHHCCCCCCCCEEEEECCCEEEECHHHHCCCCCCHHHHHHHHHHH
TKYAVTTLKGEDVVAYSQSFDLMKWKIGIFYPKETIDGLLNSTRNTVIIMACISLFVGIV
HHHHHHHCCCCCEEEECCCCCCEEEEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ASYLFSRRLARPLQLLTNHVQKVAEGDLTLKMKVTSKDEVGELTNHFNHMVEQMNEMVSK
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
IKNSVSTVQQSTNNLHYLTNETVAASKEVSGAMDDVSGGASTLANSVDEVSEQLENMIQS
HHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VEQMNSSVGEIKGVAGKAEEASKQGLNTMRNLVRTREQSSSIVVHTEEASGKLEQRVGSI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHCCHHHHHHHHH
QNVVELIKGISDQTNLLALNASIEAARAGEQGKGFAVVAEEVRKLAEQSKEATVEIATMI
HHHHHHHHCCCCCCCEEEEECCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GDVQVEVRRVVEVVSKLKDIADIQNNVTTEAEAEFRTIMSVVNTISTSVEQIVEEVHNIG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HEQGEITAVMHTIAGTSQESAAVSEEVNAATESQVNHLEKVAHTMESLTEHMRDLERLVE
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFKIEE
HHCCCC
>Mature Secondary Structure
MLRSLRLKIAVVFSVLISMMFVILGTAMYELQKEKEVRSLDQYSQNTMDLVTEQLTTFVQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTDEDMGYYANSEMIRNMLQDGVTPEEEAFLTKEFSEYKKNHPGILDLYIGTKDKKTLSA
HCCHHCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHC
NLAEGGKVPEGYDPTTRPWYKDSEGDVKTVHWGQPMYEIATGKLSVGVSKAITAQDGSVL
CHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHCCCEECCHHHHEECCCCCEE
GVVAMDVSLGTIQKLLHNIQYNNGGEMFIINDKNMALVYPEKIGKDVSKEPLVKSLNKDV
EEEEECCCHHHHHHHHHHCCCCCCCCEEEEECCCEEEECHHHHCCCCCCHHHHHHHHHHH
TKYAVTTLKGEDVVAYSQSFDLMKWKIGIFYPKETIDGLLNSTRNTVIIMACISLFVGIV
HHHHHHHCCCCCEEEECCCCCCEEEEEEEECCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ASYLFSRRLARPLQLLTNHVQKVAEGDLTLKMKVTSKDEVGELTNHFNHMVEQMNEMVSK
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
IKNSVSTVQQSTNNLHYLTNETVAASKEVSGAMDDVSGGASTLANSVDEVSEQLENMIQS
HHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VEQMNSSVGEIKGVAGKAEEASKQGLNTMRNLVRTREQSSSIVVHTEEASGKLEQRVGSI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHCCHHHHHHHHH
QNVVELIKGISDQTNLLALNASIEAARAGEQGKGFAVVAEEVRKLAEQSKEATVEIATMI
HHHHHHHHCCCCCCCEEEEECCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GDVQVEVRRVVEVVSKLKDIADIQNNVTTEAEAEFRTIMSVVNTISTSVEQIVEEVHNIG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HEQGEITAVMHTIAGTSQESAAVSEEVNAATESQVNHLEKVAHTMESLTEHMRDLERLVE
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFKIEE
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353924; 9384377 [H]