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The map label for this gene is steT [H]

Identifier: 52140515

GI number: 52140515

Start: 4836474

End: 4837790

Strand: Reverse

Name: steT [H]

Synonym: BCZK4743

Alternate gene names: 52140515

Gene position: 4837790-4836474 (Counterclockwise)

Preceding gene: 52140513

Following gene: 52140516

Centisome position: 91.26

GC content: 36.83

Gene sequence:

>1317_bases
ATGCATCATGATGAGAAGAACAAAATTGGTTTAACGGTAGCACTTTCTATCGTAGTAGGAACGATTATTGGGTCTGGTGT
GTTTATGAAACCAGGGAGCGTATTAGATTACTCGGGGAGTTCTAATATGGCGATTCTTGCTTGGGTAATTGGTGGTCTGT
TAACGTTAGCAAGCGGTTTAACAGTAGCTGAAATAGGAGCGCAAATCCCGAAAAATGGTGGGTTGTATACGTATTTAGAG
GAGATTTACGGAAGTTTTTGGGGATATTTATCAGGCTGGATGCAAACGATTGTGTATGGGCCAGCTATTATTGGAACATT
AGGGCTATACTTTAGTTCTTTAATGATTAATTTTTTCTATTTAGATAAAGTATGGAATTTACCAATCGCAATTGGAACAG
TTGTGTTCCTTGGCGTTGTAAATAGTATGGGAACAAAATACGGAGGTATCGTTCAAACGATCACGACAATCGGGAAAATG
ATTCCAATCGTATTAATTGTTGTGTTAGGTTTTTGGAAAGGGAATAGCGATATCTTTAACGTAGTTGTGCCGATATCAGA
AAATCAAAGTATCGGGATGGCGATTTTAGCAACATTATTTGCTTATGACGGCTGGATTCTACTTGCGTCAATTGGCGGAG
AAATGAAGAATCCAACAAAGTTATTACCGAAAGCAATGACAGTTGGGATTTTAATTGTAACAGCTGCTTACGTATTAATT
AATTTGGCACTATTAAATGTATTACCAGCAGTGGAAATTGTGGACCTTGGAGAAAATGCAACAGCGACAGCTGCGGGCAT
GTTACTTGGAGAATATGGTGGAAAAATTATTAGTATCGGTATTATCGTGTCTATTTTCGGTTGTTTAAATGGAAAGATTT
TAACGTTCCCACGTATCCCGATGTCGATGGCAGAACGTGGACAACTTCCATTTGCTAAGTTTATTGCAAAAGAAAGTCCA
AGATTTAAAACACCAGCAAATGCAATTACTGTTGAAATTATTTTAGGAATTATTTTAATGATTATTAGTGATCCGAATAA
GCTATCTGAGATTTCCGTATTCATTATTTATATTTTCTACGTAATGACGTTTATCGGTGTCTTTATTTTAAGAAAACGTA
ATAAGAATAAAGAGCGTGCATACAGTGTACCGTTATTCCCAATCGTACCAATCGTTGCGATTTTCGGTTCGCTCTTTGTA
ATTGGTAGTGCGATTATCAACGATCCACTAAGTTGTTTCTTATCCATTGGAATTGTCTTTACGGGACTGCCGGTGTATTG
GTATTTAAACAAGAAGAACAAAACTGAAGTGTCATAA

Upstream 100 bases:

>100_bases
AGGGTGGAACCACGAATATAACACTCGTCCCTTTTTTAGGGAGGAGTGTTTTTTTATTTCATTTTTGCATCACACTAGGA
TTGGAAGGAGGATACGCAGC

Downstream 100 bases:

>100_bases
TTGAAAGGTAGGCGTATCATACGCCTACCTTTTTTGCTGTAAAAAAATTGTACTTGTGTTCAACTTCTATTTTGGTTACT
ATAGTAGTAGTAACCAAAAT

Product: amino acid permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MHHDEKNKIGLTVALSIVVGTIIGSGVFMKPGSVLDYSGSSNMAILAWVIGGLLTLASGLTVAEIGAQIPKNGGLYTYLE
EIYGSFWGYLSGWMQTIVYGPAIIGTLGLYFSSLMINFFYLDKVWNLPIAIGTVVFLGVVNSMGTKYGGIVQTITTIGKM
IPIVLIVVLGFWKGNSDIFNVVVPISENQSIGMAILATLFAYDGWILLASIGGEMKNPTKLLPKAMTVGILIVTAAYVLI
NLALLNVLPAVEIVDLGENATATAAGMLLGEYGGKIISIGIIVSIFGCLNGKILTFPRIPMSMAERGQLPFAKFIAKESP
RFKTPANAITVEIILGIILMIISDPNKLSEISVFIIYIFYVMTFIGVFILRKRNKNKERAYSVPLFPIVPIVAIFGSLFV
IGSAIINDPLSCFLSIGIVFTGLPVYWYLNKKNKTEVS

Sequences:

>Translated_438_residues
MHHDEKNKIGLTVALSIVVGTIIGSGVFMKPGSVLDYSGSSNMAILAWVIGGLLTLASGLTVAEIGAQIPKNGGLYTYLE
EIYGSFWGYLSGWMQTIVYGPAIIGTLGLYFSSLMINFFYLDKVWNLPIAIGTVVFLGVVNSMGTKYGGIVQTITTIGKM
IPIVLIVVLGFWKGNSDIFNVVVPISENQSIGMAILATLFAYDGWILLASIGGEMKNPTKLLPKAMTVGILIVTAAYVLI
NLALLNVLPAVEIVDLGENATATAAGMLLGEYGGKIISIGIIVSIFGCLNGKILTFPRIPMSMAERGQLPFAKFIAKESP
RFKTPANAITVEIILGIILMIISDPNKLSEISVFIIYIFYVMTFIGVFILRKRNKNKERAYSVPLFPIVPIVAIFGSLFV
IGSAIINDPLSCFLSIGIVFTGLPVYWYLNKKNKTEVS
>Mature_438_residues
MHHDEKNKIGLTVALSIVVGTIIGSGVFMKPGSVLDYSGSSNMAILAWVIGGLLTLASGLTVAEIGAQIPKNGGLYTYLE
EIYGSFWGYLSGWMQTIVYGPAIIGTLGLYFSSLMINFFYLDKVWNLPIAIGTVVFLGVVNSMGTKYGGIVQTITTIGKM
IPIVLIVVLGFWKGNSDIFNVVVPISENQSIGMAILATLFAYDGWILLASIGGEMKNPTKLLPKAMTVGILIVTAAYVLI
NLALLNVLPAVEIVDLGENATATAAGMLLGEYGGKIISIGIIVSIFGCLNGKILTFPRIPMSMAERGQLPFAKFIAKESP
RFKTPANAITVEIILGIILMIISDPNKLSEISVFIIYIFYVMTFIGVFILRKRNKNKERAYSVPLFPIVPIVAIFGSLFV
IGSAIINDPLSCFLSIGIVFTGLPVYWYLNKKNKTEVS

Specific function: Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family [H]

Homologues:

Organism=Homo sapiens, GI187423910, Length=444, Percent_Identity=31.5315315315315, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI7657591, Length=444, Percent_Identity=31.5315315315315, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI33286428, Length=452, Percent_Identity=30.3097345132743, Blast_Score=182, Evalue=8e-46,
Organism=Homo sapiens, GI115648063, Length=443, Percent_Identity=29.7968397291196, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI115648022, Length=443, Percent_Identity=29.7968397291196, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI186910308, Length=432, Percent_Identity=28.0092592592593, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI186910306, Length=432, Percent_Identity=28.0092592592593, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI186910304, Length=432, Percent_Identity=28.0092592592593, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI7657683, Length=431, Percent_Identity=29.6983758700696, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI71979932, Length=441, Percent_Identity=29.2517006802721, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI9790235, Length=434, Percent_Identity=29.9539170506912, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI33286430, Length=255, Percent_Identity=30.1960784313725, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI71999149, Length=411, Percent_Identity=25.7907542579075, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI258645169, Length=399, Percent_Identity=24.5614035087719, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI258614003, Length=399, Percent_Identity=24.812030075188, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI258614005, Length=401, Percent_Identity=24.6882793017456, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI114326544, Length=409, Percent_Identity=22.2493887530562, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI114326550, Length=409, Percent_Identity=22.2493887530562, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI87082250, Length=442, Percent_Identity=27.6018099547511, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1786694, Length=390, Percent_Identity=24.6153846153846, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI2367353, Length=401, Percent_Identity=26.6832917705736, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787890, Length=453, Percent_Identity=23.1788079470199, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI87081708, Length=414, Percent_Identity=22.2222222222222, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI87081915, Length=396, Percent_Identity=23.989898989899, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17568033, Length=452, Percent_Identity=28.0973451327434, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17540018, Length=436, Percent_Identity=28.4403669724771, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71993915, Length=400, Percent_Identity=28, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI32566699, Length=310, Percent_Identity=30.9677419354839, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71995388, Length=453, Percent_Identity=26.4900662251656, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI71995382, Length=453, Percent_Identity=26.4900662251656, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI71982612, Length=452, Percent_Identity=26.3274336283186, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI71982608, Length=452, Percent_Identity=26.3274336283186, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71990446, Length=451, Percent_Identity=26.6075388026608, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI193208714, Length=401, Percent_Identity=24.1895261845387, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI32566695, Length=401, Percent_Identity=24.1895261845387, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17533459, Length=403, Percent_Identity=27.0471464019851, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17532491, Length=362, Percent_Identity=27.0718232044199, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71982623, Length=280, Percent_Identity=27.5, Blast_Score=88, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17531343, Length=379, Percent_Identity=23.2189973614776, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71987339, Length=80, Percent_Identity=37.5, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6321751, Length=441, Percent_Identity=24.2630385487528, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6321492, Length=364, Percent_Identity=22.8021978021978, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24651635, Length=445, Percent_Identity=28.9887640449438, Blast_Score=173, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24651633, Length=445, Percent_Identity=28.9887640449438, Blast_Score=173, Evalue=3e-43,
Organism=Drosophila melanogaster, GI45550968, Length=441, Percent_Identity=26.984126984127, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI19921172, Length=441, Percent_Identity=26.984126984127, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI221331183, Length=436, Percent_Identity=28.6697247706422, Blast_Score=155, Evalue=6e-38,
Organism=Drosophila melanogaster, GI17647653, Length=436, Percent_Identity=28.6697247706422, Blast_Score=155, Evalue=6e-38,
Organism=Drosophila melanogaster, GI24664379, Length=436, Percent_Identity=28.6697247706422, Blast_Score=155, Evalue=6e-38,
Organism=Drosophila melanogaster, GI21357367, Length=433, Percent_Identity=27.9445727482679, Blast_Score=155, Evalue=7e-38,
Organism=Drosophila melanogaster, GI24641995, Length=392, Percent_Identity=27.2959183673469, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24641993, Length=392, Percent_Identity=27.2959183673469, Blast_Score=138, Evalue=8e-33,
Organism=Drosophila melanogaster, GI24667468, Length=395, Percent_Identity=25.0632911392405, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI281366235, Length=395, Percent_Identity=25.0632911392405, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI116007820, Length=395, Percent_Identity=25.0632911392405, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24666159, Length=396, Percent_Identity=22.979797979798, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221512776, Length=396, Percent_Identity=22.979797979798, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI116007818, Length=349, Percent_Identity=26.3610315186246, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI85725152, Length=349, Percent_Identity=26.3610315186246, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24668806, Length=398, Percent_Identity=24.3718592964824, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356285, Length=398, Percent_Identity=24.3718592964824, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24668802, Length=398, Percent_Identity=24.3718592964824, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 47277; Mature: 47277

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHHDEKNKIGLTVALSIVVGTIIGSGVFMKPGSVLDYSGSSNMAILAWVIGGLLTLASGL
CCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCEEEECCCCCHHHHHHHHHHHHHHHCCC
TVAEIGAQIPKNGGLYTYLEEIYGSFWGYLSGWMQTIVYGPAIIGTLGLYFSSLMINFFY
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDKVWNLPIAIGTVVFLGVVNSMGTKYGGIVQTITTIGKMIPIVLIVVLGFWKGNSDIFN
HHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
VVVPISENQSIGMAILATLFAYDGWILLASIGGEMKNPTKLLPKAMTVGILIVTAAYVLI
EEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NLALLNVLPAVEIVDLGENATATAAGMLLGEYGGKIISIGIIVSIFGCLNGKILTFPRIP
HHHHHHHHCCHHEEECCCCCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHCCCEEEECCCC
MSMAERGQLPFAKFIAKESPRFKTPANAITVEIILGIILMIISDPNKLSEISVFIIYIFY
HHHHHCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VMTFIGVFILRKRNKNKERAYSVPLFPIVPIVAIFGSLFVIGSAIINDPLSCFLSIGIVF
HHHHHHHHHHHHCCCCCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGLPVYWYLNKKNKTEVS
HCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MHHDEKNKIGLTVALSIVVGTIIGSGVFMKPGSVLDYSGSSNMAILAWVIGGLLTLASGL
CCCCCCCCCHHHHHHHHHHHHHHCCCEEECCCCEEEECCCCCHHHHHHHHHHHHHHHCCC
TVAEIGAQIPKNGGLYTYLEEIYGSFWGYLSGWMQTIVYGPAIIGTLGLYFSSLMINFFY
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDKVWNLPIAIGTVVFLGVVNSMGTKYGGIVQTITTIGKMIPIVLIVVLGFWKGNSDIFN
HHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
VVVPISENQSIGMAILATLFAYDGWILLASIGGEMKNPTKLLPKAMTVGILIVTAAYVLI
EEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
NLALLNVLPAVEIVDLGENATATAAGMLLGEYGGKIISIGIIVSIFGCLNGKILTFPRIP
HHHHHHHHCCHHEEECCCCCHHHHHHHHHHHHCCCEEHHHHHHHHHHHHCCCEEEECCCC
MSMAERGQLPFAKFIAKESPRFKTPANAITVEIILGIILMIISDPNKLSEISVFIIYIFY
HHHHHCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
VMTFIGVFILRKRNKNKERAYSVPLFPIVPIVAIFGSLFVIGSAIINDPLSCFLSIGIVF
HHHHHHHHHHHHCCCCCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGLPVYWYLNKKNKTEVS
HCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]