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The map label for this gene is murB [H]

Identifier: 52140460

GI number: 52140460

Start: 4893313

End: 4894230

Strand: Reverse

Name: murB [H]

Synonym: BCZK4798

Alternate gene names: 52140460

Gene position: 4894230-4893313 (Counterclockwise)

Preceding gene: 52140458

Following gene: 52140461

Centisome position: 92.33

GC content: 36.93

Gene sequence:

>918_bases
ATGAATATGCAAGAGGTTTATGAATATTTAAGTACGGTATTGCCTGAAGGTCATGTGAAACAAGATGAAATGTTAAAGAA
TCATACGCATATTAAAGTTGGTGGAAAAGCAGATGTGTTCGTTGCGCCGACAAATTATGATGAAATTCAAGAAGTTATTA
AATATGCTAACAAATATAATATTCCAGTTACGTTTTTAGGGAACGGTTCGAATGTCATTATTAAAGATGGTGGAATTCGC
GGGATTACAGTAAGTTTAATTCATATTACAGGTGTTACTGTAACAGGAACGACAATTGTAGCACAGTGCGGTGCAGCAAT
TATTGACGTATCACGTATTGCGTTAGACCATAACTTAACGGGTCTTGAGTTTGCTTGTGGTATTCCGGGTTCAGTTGGCG
GAGCATTGTATATGAATGCTGGTGCATACGGCGGTGAAATTTCGTTTGTATTAACAGAAGCTGTTGTAATGACAGGTGAT
GGAGAGCTACGTACTTTGACGAAAGAAGCATTTGAATTTGGATATCGTAAGAGTGTATTTGCGAACAACCATTACATTAT
TCTGGAAGCGAGATTTGAACTTGAAGAAGGTGTACATGAAGAAATTAAAGCAAAAATGGATGATTTAACGTTTAAACGTG
AGTCAAAACAACCTCTAGAATATCCTTCATGTGGTAGCGTATTTAAACGCCCACCAAATAACTTTGCTGGCAAATTGATT
CAAGATTCAGGACTACAAGGTAAGCGAATTGGCGGAGTGGAAGTTTCTCTAAAACACGCTGGATTTATGGTAAATGTTGA
TAACGGAACAGCACAAGATTACATCGATTTAATTCACTTCGTACAAAAAACAGTTGAAGAGAAATTTGGCGTGAAGTTAG
AGCGCGAAGTAAGGATTATTGGAGAAGATAAAGAATAA

Upstream 100 bases:

>100_bases
GGTACACTGTATCCACCACTTTAGGTTCGTTCATGTATGTGGGGATATTATGGGCCCGTATAACGGGATAAAAAGAATAT
AGAAATAGAGGAATCGTAAA

Downstream 100 bases:

>100_bases
TATATACGTATGAAACTGCGAATTATTTTAAAATAATATTTGGGTATTGTTGACAATTTGTTTACAATTCAATATAATGG
CTAATAATTTAACAAATAAC

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase 2 [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MNMQEVYEYLSTVLPEGHVKQDEMLKNHTHIKVGGKADVFVAPTNYDEIQEVIKYANKYNIPVTFLGNGSNVIIKDGGIR
GITVSLIHITGVTVTGTTIVAQCGAAIIDVSRIALDHNLTGLEFACGIPGSVGGALYMNAGAYGGEISFVLTEAVVMTGD
GELRTLTKEAFEFGYRKSVFANNHYIILEARFELEEGVHEEIKAKMDDLTFKRESKQPLEYPSCGSVFKRPPNNFAGKLI
QDSGLQGKRIGGVEVSLKHAGFMVNVDNGTAQDYIDLIHFVQKTVEEKFGVKLEREVRIIGEDKE

Sequences:

>Translated_305_residues
MNMQEVYEYLSTVLPEGHVKQDEMLKNHTHIKVGGKADVFVAPTNYDEIQEVIKYANKYNIPVTFLGNGSNVIIKDGGIR
GITVSLIHITGVTVTGTTIVAQCGAAIIDVSRIALDHNLTGLEFACGIPGSVGGALYMNAGAYGGEISFVLTEAVVMTGD
GELRTLTKEAFEFGYRKSVFANNHYIILEARFELEEGVHEEIKAKMDDLTFKRESKQPLEYPSCGSVFKRPPNNFAGKLI
QDSGLQGKRIGGVEVSLKHAGFMVNVDNGTAQDYIDLIHFVQKTVEEKFGVKLEREVRIIGEDKE
>Mature_305_residues
MNMQEVYEYLSTVLPEGHVKQDEMLKNHTHIKVGGKADVFVAPTNYDEIQEVIKYANKYNIPVTFLGNGSNVIIKDGGIR
GITVSLIHITGVTVTGTTIVAQCGAAIIDVSRIALDHNLTGLEFACGIPGSVGGALYMNAGAYGGEISFVLTEAVVMTGD
GELRTLTKEAFEFGYRKSVFANNHYIILEARFELEEGVHEEIKAKMDDLTFKRESKQPLEYPSCGSVFKRPPNNFAGKLI
QDSGLQGKRIGGVEVSLKHAGFMVNVDNGTAQDYIDLIHFVQKTVEEKFGVKLEREVRIIGEDKE

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 33507; Mature: 33507

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMQEVYEYLSTVLPEGHVKQDEMLKNHTHIKVGGKADVFVAPTNYDEIQEVIKYANKYN
CCHHHHHHHHHHHCCCCCCCHHHHHHCCCEEEECCCEEEEEECCCHHHHHHHHHHHHCCC
IPVTFLGNGSNVIIKDGGIRGITVSLIHITGVTVTGTTIVAQCGAAIIDVSRIALDHNLT
CEEEEEECCCEEEEECCCCCEEEEEEEEEEEEEEECHHHHHHCCHHHHHHHHHHCCCCCC
GLEFACGIPGSVGGALYMNAGAYGGEISFVLTEAVVMTGDGELRTLTKEAFEFGYRKSVF
CEEEECCCCCCCCCEEEEECCCCCCEEEEEEEEEEEEECCCCHHHHHHHHHHCCCCCEEE
ANNHYIILEARFELEEGVHEEIKAKMDDLTFKRESKQPLEYPSCGSVFKRPPNNFAGKLI
ECCCEEEEEEEECHHCCHHHHHHHHHHHHEECCCCCCCCCCCCCCHHHCCCCCHHHHHHH
QDSGLQGKRIGGVEVSLKHAGFMVNVDNGTAQDYIDLIHFVQKTVEEKFGVKLEREVRII
HCCCCCCCCCCCEEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEEE
GEDKE
ECCCC
>Mature Secondary Structure
MNMQEVYEYLSTVLPEGHVKQDEMLKNHTHIKVGGKADVFVAPTNYDEIQEVIKYANKYN
CCHHHHHHHHHHHCCCCCCCHHHHHHCCCEEEECCCEEEEEECCCHHHHHHHHHHHHCCC
IPVTFLGNGSNVIIKDGGIRGITVSLIHITGVTVTGTTIVAQCGAAIIDVSRIALDHNLT
CEEEEEECCCEEEEECCCCCEEEEEEEEEEEEEEECHHHHHHCCHHHHHHHHHHCCCCCC
GLEFACGIPGSVGGALYMNAGAYGGEISFVLTEAVVMTGDGELRTLTKEAFEFGYRKSVF
CEEEECCCCCCCCCEEEEECCCCCCEEEEEEEEEEEEECCCCHHHHHHHHHHCCCCCEEE
ANNHYIILEARFELEEGVHEEIKAKMDDLTFKRESKQPLEYPSCGSVFKRPPNNFAGKLI
ECCCEEEEEEEECHHCCHHHHHHHHHHHHEECCCCCCCCCCCCCCHHHCCCCCHHHHHHH
QDSGLQGKRIGGVEVSLKHAGFMVNVDNGTAQDYIDLIHFVQKTVEEKFGVKLEREVRII
HCCCCCCCCCCCEEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEEEE
GEDKE
ECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]