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The map label for this gene is arlR [H]

Identifier: 52140441

GI number: 52140441

Start: 4908197

End: 4908874

Strand: Reverse

Name: arlR [H]

Synonym: BCZK4816

Alternate gene names: 52140441

Gene position: 4908874-4908197 (Counterclockwise)

Preceding gene: 52140442

Following gene: 52140443

Centisome position: 92.6

GC content: 34.07

Gene sequence:

>678_bases
GTGAGGCAGGTGTTAGTAATTAAAAATGAACGGTCTCTAGCAAAGAAAATCGTAAGCGGTTTAATGGAAGAAGGCCATTT
CATTTTAAAACTTCACAATGAAAACGAAGGTTTAAATATAATATATGAACAAGATTGGGATATTATCATATTAGATTGGG
ATTCATTAAGCATATCCGGACCAGAAATTTGCAGACAAATACGGCTTGTTAAAATGACACCGGTCATTATTGTGACCGAC
AATATTTCTAGCAAGGATTGCGTAGCTGGGTTACAAGCAGGAGCTGATGATTATATAAGAAAACCATTTGCGAAAGAAGA
ATTAGTAGCAAGGGTTCAAGCTATTTTAAGGAGAAGCGACTGTAACCTGCAAAATGAGATAACCTTTTATCAGTTTAAAG
ATCTCTTTGTTGATGCATCTAGCAATATTGTGAAAAAAGGTGGTAAAAATCTCTCGCTTACGAAGCGTGAGTACGATTTA
CTTGTATTTTTAATTAAGAATAAAAATACAATATTGAGCCGTGAAATGCTTTTGAACCAAGTTTGGGGACATAACGTAGT
CGTAAATCCAAATGTAGTAGACTTATATATTGGGTATGTAAGAAAAAAGCTAAAGTGTGAGAAGAAAAATAGATATATTC
AAACGATACATGGCAGAGGCTATTCAATGGTTGAATGA

Upstream 100 bases:

>100_bases
TAATAAGCTGTTTGAATGGATTTTTTAGGGATTTAATATTTATAAATCTTAAATAATTTTTTATCTAACTAAGTTATATT
GAAGTAGAGGTGAACCATCG

Downstream 100 bases:

>100_bases
TAAAAATAAGATAATAAAGTAGTTTCTGTGAAATATGAAAAGACAGAAACTATAAAAAGAAGATTGCTATCAGGAAATGG
TCATTTTTTTGCAGTAGAAA

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MRQVLVIKNERSLAKKIVSGLMEEGHFILKLHNENEGLNIIYEQDWDIIILDWDSLSISGPEICRQIRLVKMTPVIIVTD
NISSKDCVAGLQAGADDYIRKPFAKEELVARVQAILRRSDCNLQNEITFYQFKDLFVDASSNIVKKGGKNLSLTKREYDL
LVFLIKNKNTILSREMLLNQVWGHNVVVNPNVVDLYIGYVRKKLKCEKKNRYIQTIHGRGYSMVE

Sequences:

>Translated_225_residues
MRQVLVIKNERSLAKKIVSGLMEEGHFILKLHNENEGLNIIYEQDWDIIILDWDSLSISGPEICRQIRLVKMTPVIIVTD
NISSKDCVAGLQAGADDYIRKPFAKEELVARVQAILRRSDCNLQNEITFYQFKDLFVDASSNIVKKGGKNLSLTKREYDL
LVFLIKNKNTILSREMLLNQVWGHNVVVNPNVVDLYIGYVRKKLKCEKKNRYIQTIHGRGYSMVE
>Mature_225_residues
MRQVLVIKNERSLAKKIVSGLMEEGHFILKLHNENEGLNIIYEQDWDIIILDWDSLSISGPEICRQIRLVKMTPVIIVTD
NISSKDCVAGLQAGADDYIRKPFAKEELVARVQAILRRSDCNLQNEITFYQFKDLFVDASSNIVKKGGKNLSLTKREYDL
LVFLIKNKNTILSREMLLNQVWGHNVVVNPNVVDLYIGYVRKKLKCEKKNRYIQTIHGRGYSMVE

Specific function: Member of the two-component regulatory system ArlS/ArlR involved in the regulation of adhesion, autolysis, multidrug resistance and virulence [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=34.0807174887892, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=31.981981981982, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=31.5555555555556, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=33.6322869955157, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=29.4642857142857, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=31.2217194570136, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI2367329, Length=174, Percent_Identity=36.7816091954023, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=30.5309734513274, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=29.4372294372294, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=28.6363636363636, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=30.1801801801802, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=28.6995515695067, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=26.431718061674, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25941; Mature: 25941

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQVLVIKNERSLAKKIVSGLMEEGHFILKLHNENEGLNIIYEQDWDIIILDWDSLSISG
CCEEEEEECCHHHHHHHHHHHHHCCEEEEEEECCCCCEEEEEECCCCEEEEECCCCCCCC
PEICRQIRLVKMTPVIIVTDNISSKDCVAGLQAGADDYIRKPFAKEELVARVQAILRRSD
HHHHHHEEEEEECEEEEEECCCCCHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHCC
CNLQNEITFYQFKDLFVDASSNIVKKGGKNLSLTKREYDLLVFLIKNKNTILSREMLLNQ
CCCCCCEEEEEEEEEEEECCCHHHHCCCCCCEEEEECEEEEEEEEECCCCHHHHHHHHHH
VWGHNVVVNPNVVDLYIGYVRKKLKCEKKNRYIQTIHGRGYSMVE
HCCCCEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MRQVLVIKNERSLAKKIVSGLMEEGHFILKLHNENEGLNIIYEQDWDIIILDWDSLSISG
CCEEEEEECCHHHHHHHHHHHHHCCEEEEEEECCCCCEEEEEECCCCEEEEECCCCCCCC
PEICRQIRLVKMTPVIIVTDNISSKDCVAGLQAGADDYIRKPFAKEELVARVQAILRRSD
HHHHHHEEEEEECEEEEEECCCCCHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHCC
CNLQNEITFYQFKDLFVDASSNIVKKGGKNLSLTKREYDLLVFLIKNKNTILSREMLLNQ
CCCCCCEEEEEEEEEEEECCCHHHHCCCCCCEEEEECEEEEEEEEECCCCHHHHHHHHHH
VWGHNVVVNPNVVDLYIGYVRKKLKCEKKNRYIQTIHGRGYSMVE
HCCCCEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA