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The map label for this gene is lrgB [H]

Identifier: 52140436

GI number: 52140436

Start: 4914270

End: 4914962

Strand: Reverse

Name: lrgB [H]

Synonym: BCZK4821

Alternate gene names: 52140436

Gene position: 4914962-4914270 (Counterclockwise)

Preceding gene: 52140437

Following gene: 52140438

Centisome position: 92.72

GC content: 39.25

Gene sequence:

>693_bases
ATGAGTCAAATATTAATCGGGATCGGTTGGGTTCTTTTTACGGTGCTATTATATCAATTATCTAAAAAAATCTATAAATT
ATTTCCAACACCATTCACCATTCCAATGCTTGTAGCAACAGGATTAATGGCTTTCTTATTGATCGTGCTTGATATACCAT
ATCAACATTATATGGAAAGTGGTGGCGGCTGGATTGCAAAACTGCTCGGACCCGGTGTTGTAGCATTTGCAATCCCTCTT
TATAAACAACGTCACGTTCTGCAAAAGTATGTTGTACCGATTGCGGGTGGTGTATTAGTAGGTACAACAGTTGCCATCGC
AAGTGACTTTGCTATTGCCTCACTTATGGGAACAGATAAAAGCTTAATTTTATCTTCTTTACCAAAATCGGTGACAATGC
CAGTTGCGATGAGTGTTTCGGAGCAAGTTGGTGGTGTACCGTCATTAACAGCAGCTTTCGTTGTTATTGCAGGTATTACT
GGAACGATTACTGGACCGCTTTTATTAAAATGGAGCCGTGTTACAAACTCAGTTGGTAAAGGGATCGGATTTGGATGTGC
TTCTCATATTATGGGTGTGATGAGAGCGATGAAAAATAATGAACATGAAGGTGTTATTGGATCGGTAACAATGACATTAA
CAGCCATTTTAACATGTTTGCTCGGGCCGTTATTTGCAATGATGTTCATGTAA

Upstream 100 bases:

>100_bases
TTTCTCTTTTCATTACAGTTGTAGCGAGTACATTTTTAATTATTATTGTCGCAGGACATACAGGACAATATCTTGCGAAT
AGAAAGGAAAGAGAGTCGCG

Downstream 100 bases:

>100_bases
GAGAAGAAAAACGAGAGCGACCTTATAGCTCTCGCTTTTCTATAGGATTTATGCTACAGTTACAATAACTGAATTTTTGT
AGGAGGTACGCCAAGTGCAT

Product: murein hydrolase export regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MSQILIGIGWVLFTVLLYQLSKKIYKLFPTPFTIPMLVATGLMAFLLIVLDIPYQHYMESGGGWIAKLLGPGVVAFAIPL
YKQRHVLQKYVVPIAGGVLVGTTVAIASDFAIASLMGTDKSLILSSLPKSVTMPVAMSVSEQVGGVPSLTAAFVVIAGIT
GTITGPLLLKWSRVTNSVGKGIGFGCASHIMGVMRAMKNNEHEGVIGSVTMTLTAILTCLLGPLFAMMFM

Sequences:

>Translated_230_residues
MSQILIGIGWVLFTVLLYQLSKKIYKLFPTPFTIPMLVATGLMAFLLIVLDIPYQHYMESGGGWIAKLLGPGVVAFAIPL
YKQRHVLQKYVVPIAGGVLVGTTVAIASDFAIASLMGTDKSLILSSLPKSVTMPVAMSVSEQVGGVPSLTAAFVVIAGIT
GTITGPLLLKWSRVTNSVGKGIGFGCASHIMGVMRAMKNNEHEGVIGSVTMTLTAILTCLLGPLFAMMFM
>Mature_229_residues
SQILIGIGWVLFTVLLYQLSKKIYKLFPTPFTIPMLVATGLMAFLLIVLDIPYQHYMESGGGWIAKLLGPGVVAFAIPLY
KQRHVLQKYVVPIAGGVLVGTTVAIASDFAIASLMGTDKSLILSSLPKSVTMPVAMSVSEQVGGVPSLTAAFVVIAGITG
TITGPLLLKWSRVTNSVGKGIGFGCASHIMGVMRAMKNNEHEGVIGSVTMTLTAILTCLLGPLFAMMFM

Specific function: Unknown

COG id: COG1346

COG function: function code M; Putative effector of murein hydrolase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the yohK (E.coli)/ywbG (IPA-22R) (B.subtilis) family [H]

Homologues:

Organism=Escherichia coli, GI1788464, Length=220, Percent_Identity=33.1818181818182, Blast_Score=122, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007300 [H]

Pfam domain/function: PF04172 LrgB [H]

EC number: NA

Molecular weight: Translated: 24378; Mature: 24247

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQILIGIGWVLFTVLLYQLSKKIYKLFPTPFTIPMLVATGLMAFLLIVLDIPYQHYMES
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHC
GGGWIAKLLGPGVVAFAIPLYKQRHVLQKYVVPIAGGVLVGTTVAIASDFAIASLMGTDK
CCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCH
SLILSSLPKSVTMPVAMSVSEQVGGVPSLTAAFVVIAGITGTITGPLLLKWSRVTNSVGK
HHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
GIGFGCASHIMGVMRAMKNNEHEGVIGSVTMTLTAILTCLLGPLFAMMFM
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
SQILIGIGWVLFTVLLYQLSKKIYKLFPTPFTIPMLVATGLMAFLLIVLDIPYQHYMES
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHC
GGGWIAKLLGPGVVAFAIPLYKQRHVLQKYVVPIAGGVLVGTTVAIASDFAIASLMGTDK
CCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCH
SLILSSLPKSVTMPVAMSVSEQVGGVPSLTAAFVVIAGITGTITGPLLLKWSRVTNSVGK
HHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
GIGFGCASHIMGVMRAMKNNEHEGVIGSVTMTLTAILTCLLGPLFAMMFM
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7584049; 9384377; 10568751 [H]