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The map label for this gene is vba [H]

Identifier: 52140387

GI number: 52140387

Start: 4958474

End: 4960108

Strand: Direct

Name: vba [H]

Synonym: BCZK4873

Alternate gene names: 52140387

Gene position: 4958474-4960108 (Clockwise)

Preceding gene: 52140388

Following gene: 52140369

Centisome position: 93.54

GC content: 37.92

Gene sequence:

>1635_bases
ATGACTATTTTATTCGCACGTAATATTGAGAAGAGCTTTGGTGATCGCACACTATTTACGTTACCGTCACTGGAAATTCA
AGCACGGGATCGCATAGGAATTGTCGGCGTCAACGGGGCTGGTAAATCTACGTTACTACAAATATTAAGTAAAGAAATAG
AAGCTGACAAAGGCATAGTAACTCACCATAGCTCTATCAGCATCATTCCTCAAATTAGCGAGGAATTACCAAAAGTCGCT
TCTTCTACAGCAAAAGGAAAATGGAATATTTCAAACATCTCAAATTCAATGAGCGGCGGGGAACGAATGCGTCTAAAGAT
TGCCCATGCTCTCGAACAAGATGCAGGCATTCTATTCGCTGATGAACCAACAAGCCACTTAGATATGTTCGGTACAGAGC
AATTAGAAAAGGCACTTTTATCTTATAAAGGTGCACTTGTTTTAATATCACATGATCGTGAATTTCTAGATAATATATGC
ACAAAAATCATTGAAATTGAAGACGGGATAATTCAAGAATATAAAGGAAACTATTCCAACTATCGAAAGCAAAAAGAACG
TGAACGAACACAAAAACAAGCAGAATACGAGCAGTATATAAACGAAAAAGAGCGTTTAGAGAAGTCCATTTTACAAAAAA
AGCAACGTGCTTCTAGCATGACAAAAATCCCAACACGGTTCAGTTCATCTGAATCTAAACTTTATAAATTAAGTGGGGCT
CATGGCCAAGAACAGGTTAGTAAAGCAGCAAAAGCATTAGAGACACGTCTTGAAAAACTAGAAAAGAAAGAAAAGCCAAA
GGAGCTTTCTCAAGCCCAGTTTGACGTACAATACCATACACCCATTCATAGTAAAGTGGCAGTACAGTTCAATAAAGCAA
CAAAGAAAATAGGTGACCGCACACTATTTAAAAATATGAATGGAACGATTGCTCCTGGTGCAAAGCTTGCTATTTTAGGG
ACAAACGGAAGTGGAAAAACGACCCTGTTTAACATGCTTCTCGCAAACGAGCGTGGCATTCAGTTTTCAAAAAGTTGTAA
GATTGGGTACTTTGAACAAACACTATCCATTTTAAAAACAGATAAAACCATTTTAGAAAATGTTCTAGAAGAAACAAACT
ATACAGAGTCGTTCGTTCGCACAATACTTGCAAGGCTTCTATTCCGACGTGAAGATGTTCATAAACCTGTGCACGTTCTA
AGCGGGGGTGAGCGAATGAAGGTTGCACTCGCAAAAGTATTTTTGGGAAACTATAATATGCTTCTGCTCGATGAACCGAC
AAACTATTTAGACTTAGCGACGCAAGAAGAATTAGAAAGCATGTTACAAGAATATCCTGGCACTATACTTTTCATTAGCC
ATGACCGTGCCTTCATTCGTTCTGTTGCAGACCATATTCTACAAGTAGATGAAAGTGAACCAAGAGTATTCCACGGTAAT
TACGAGCAATACACAAACAGAACAGCCGATGCTTCTGTAAACGTTACTGCACAAGAATTATTACGATTACAAACAAAATT
AACAGAAATCATCGGCCGAATTTCCATACCAAATCATCACGATGACATCACATCTCTCGAACAAGAATACGAAACATTAT
TAGTTAAAATCCGGAAATGTAAAGAAGCACTCTAA

Upstream 100 bases:

>100_bases
TCTTTCGAAACGATCATGTAAAAAAATCGTTTATTTATGTACGATTTTTACATGCAAGGGCGACGTTTATCCTCTCTAGT
GAAACTAGGGAGGTTTTTTT

Downstream 100 bases:

>100_bases
TGTCTTCCCTATATATCGACGGGACCTTCCGCATTTCCCAAGAAATATTGAATCTTCGACATAGCATACAAAAAGCCGTG
CAGTTCATCAGCACGGCCTT

Product: MDR-type ABC transporter, ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 544; Mature: 543

Protein sequence:

>544_residues
MTILFARNIEKSFGDRTLFTLPSLEIQARDRIGIVGVNGAGKSTLLQILSKEIEADKGIVTHHSSISIIPQISEELPKVA
SSTAKGKWNISNISNSMSGGERMRLKIAHALEQDAGILFADEPTSHLDMFGTEQLEKALLSYKGALVLISHDREFLDNIC
TKIIEIEDGIIQEYKGNYSNYRKQKERERTQKQAEYEQYINEKERLEKSILQKKQRASSMTKIPTRFSSSESKLYKLSGA
HGQEQVSKAAKALETRLEKLEKKEKPKELSQAQFDVQYHTPIHSKVAVQFNKATKKIGDRTLFKNMNGTIAPGAKLAILG
TNGSGKTTLFNMLLANERGIQFSKSCKIGYFEQTLSILKTDKTILENVLEETNYTESFVRTILARLLFRREDVHKPVHVL
SGGERMKVALAKVFLGNYNMLLLDEPTNYLDLATQEELESMLQEYPGTILFISHDRAFIRSVADHILQVDESEPRVFHGN
YEQYTNRTADASVNVTAQELLRLQTKLTEIIGRISIPNHHDDITSLEQEYETLLVKIRKCKEAL

Sequences:

>Translated_544_residues
MTILFARNIEKSFGDRTLFTLPSLEIQARDRIGIVGVNGAGKSTLLQILSKEIEADKGIVTHHSSISIIPQISEELPKVA
SSTAKGKWNISNISNSMSGGERMRLKIAHALEQDAGILFADEPTSHLDMFGTEQLEKALLSYKGALVLISHDREFLDNIC
TKIIEIEDGIIQEYKGNYSNYRKQKERERTQKQAEYEQYINEKERLEKSILQKKQRASSMTKIPTRFSSSESKLYKLSGA
HGQEQVSKAAKALETRLEKLEKKEKPKELSQAQFDVQYHTPIHSKVAVQFNKATKKIGDRTLFKNMNGTIAPGAKLAILG
TNGSGKTTLFNMLLANERGIQFSKSCKIGYFEQTLSILKTDKTILENVLEETNYTESFVRTILARLLFRREDVHKPVHVL
SGGERMKVALAKVFLGNYNMLLLDEPTNYLDLATQEELESMLQEYPGTILFISHDRAFIRSVADHILQVDESEPRVFHGN
YEQYTNRTADASVNVTAQELLRLQTKLTEIIGRISIPNHHDDITSLEQEYETLLVKIRKCKEAL
>Mature_543_residues
TILFARNIEKSFGDRTLFTLPSLEIQARDRIGIVGVNGAGKSTLLQILSKEIEADKGIVTHHSSISIIPQISEELPKVAS
STAKGKWNISNISNSMSGGERMRLKIAHALEQDAGILFADEPTSHLDMFGTEQLEKALLSYKGALVLISHDREFLDNICT
KIIEIEDGIIQEYKGNYSNYRKQKERERTQKQAEYEQYINEKERLEKSILQKKQRASSMTKIPTRFSSSESKLYKLSGAH
GQEQVSKAAKALETRLEKLEKKEKPKELSQAQFDVQYHTPIHSKVAVQFNKATKKIGDRTLFKNMNGTIAPGAKLAILGT
NGSGKTTLFNMLLANERGIQFSKSCKIGYFEQTLSILKTDKTILENVLEETNYTESFVRTILARLLFRREDVHKPVHVLS
GGERMKVALAKVFLGNYNMLLLDEPTNYLDLATQEELESMLQEYPGTILFISHDRAFIRSVADHILQVDESEPRVFHGNY
EQYTNRTADASVNVTAQELLRLQTKLTEIIGRISIPNHHDDITSLEQEYETLLVKIRKCKEAL

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=455, Percent_Identity=28.1318681318681, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI10947137, Length=524, Percent_Identity=27.0992366412214, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI27881506, Length=524, Percent_Identity=27.0992366412214, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI10947135, Length=404, Percent_Identity=27.4752475247525, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI69354671, Length=404, Percent_Identity=27.4752475247525, Blast_Score=132, Evalue=7e-31,
Organism=Escherichia coli, GI1787041, Length=550, Percent_Identity=29.2727272727273, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1789751, Length=541, Percent_Identity=30.8687615526802, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI2367384, Length=432, Percent_Identity=33.5648148148148, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1787182, Length=533, Percent_Identity=26.6416510318949, Blast_Score=188, Evalue=8e-49,
Organism=Escherichia coli, GI1788165, Length=197, Percent_Identity=26.9035532994924, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788225, Length=220, Percent_Identity=25.4545454545455, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1787164, Length=198, Percent_Identity=26.2626262626263, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17559834, Length=413, Percent_Identity=26.1501210653753, Blast_Score=151, Evalue=9e-37,
Organism=Caenorhabditis elegans, GI17555318, Length=526, Percent_Identity=26.9961977186312, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17553372, Length=404, Percent_Identity=28.960396039604, Blast_Score=143, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6320874, Length=404, Percent_Identity=27.7227722772277, Blast_Score=145, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6321121, Length=421, Percent_Identity=28.2660332541568, Blast_Score=140, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6323278, Length=178, Percent_Identity=31.4606741573034, Blast_Score=100, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6324314, Length=180, Percent_Identity=30, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6325030, Length=203, Percent_Identity=31.0344827586207, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24642252, Length=547, Percent_Identity=26.508226691042, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI18859989, Length=547, Percent_Identity=26.508226691042, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24666836, Length=412, Percent_Identity=26.9417475728155, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24641342, Length=416, Percent_Identity=27.8846153846154, Blast_Score=146, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 61596; Mature: 61465

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILFARNIEKSFGDRTLFTLPSLEIQARDRIGIVGVNGAGKSTLLQILSKEIEADKGIV
CEEEEECCHHHHCCCCEEEECCCCEEEECCCEEEEEECCCCHHHHHHHHHHHHCCCCCEE
THHSSISIIPQISEELPKVASSTAKGKWNISNISNSMSGGERMRLKIAHALEQDAGILFA
EECCCEEECHHHHHHHHHHHHCCCCCCEEHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEE
DEPTSHLDMFGTEQLEKALLSYKGALVLISHDREFLDNICTKIIEIEDGIIQEYKGNYSN
CCCCHHHHHCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHH
YRKQKERERTQKQAEYEQYINEKERLEKSILQKKQRASSMTKIPTRFSSSESKLYKLSGA
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCC
HGQEQVSKAAKALETRLEKLEKKEKPKELSQAQFDVQYHTPIHSKVAVQFNKATKKIGDR
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCEEECCCCCCCEEEEEHHHHHHHCCH
TLFKNMNGTIAPGAKLAILGTNGSGKTTLFNMLLANERGIQFSKSCKIGYFEQTLSILKT
HHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHC
DKTILENVLEETNYTESFVRTILARLLFRREDVHKPVHVLSGGERMKVALAKVFLGNYNM
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHCCCCE
LLLDEPTNYLDLATQEELESMLQEYPGTILFISHDRAFIRSVADHILQVDESEPRVFHGN
EEEECCCCHHHCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCEEECC
YEQYTNRTADASVNVTAQELLRLQTKLTEIIGRISIPNHHDDITSLEQEYETLLVKIRKC
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
KEAL
HHCC
>Mature Secondary Structure 
TILFARNIEKSFGDRTLFTLPSLEIQARDRIGIVGVNGAGKSTLLQILSKEIEADKGIV
EEEEECCHHHHCCCCEEEECCCCEEEECCCEEEEEECCCCHHHHHHHHHHHHCCCCCEE
THHSSISIIPQISEELPKVASSTAKGKWNISNISNSMSGGERMRLKIAHALEQDAGILFA
EECCCEEECHHHHHHHHHHHHCCCCCCEEHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEE
DEPTSHLDMFGTEQLEKALLSYKGALVLISHDREFLDNICTKIIEIEDGIIQEYKGNYSN
CCCCHHHHHCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHH
YRKQKERERTQKQAEYEQYINEKERLEKSILQKKQRASSMTKIPTRFSSSESKLYKLSGA
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCC
HGQEQVSKAAKALETRLEKLEKKEKPKELSQAQFDVQYHTPIHSKVAVQFNKATKKIGDR
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCEEECCCCCCCEEEEEHHHHHHHCCH
TLFKNMNGTIAPGAKLAILGTNGSGKTTLFNMLLANERGIQFSKSCKIGYFEQTLSILKT
HHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHC
DKTILENVLEETNYTESFVRTILARLLFRREDVHKPVHVLSGGERMKVALAKVFLGNYNM
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHCCCCE
LLLDEPTNYLDLATQEELESMLQEYPGTILFISHDRAFIRSVADHILQVDESEPRVFHGN
EEEECCCCHHHCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCCCCCEEECC
YEQYTNRTADASVNVTAQELLRLQTKLTEIIGRISIPNHHDDITSLEQEYETLLVKIRKC
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
KEAL
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]