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The map label for this gene is slt [C]

Identifier: 51894446

GI number: 51894446

Start: 3538637

End: 3539419

Strand: Reverse

Name: slt [C]

Synonym: STH3312

Alternate gene names: 51894446

Gene position: 3539419-3538637 (Counterclockwise)

Preceding gene: 51894447

Following gene: 51894445

Centisome position: 99.25

GC content: 68.45

Gene sequence:

>783_bases
TTGCTTCGCGACAGGCTTCGACAAATTTCGCGCCCGGCGCATGGTAAAGTCTTCCTGAGGTGGGAATTCATGAGAAGCGA
CCGTGCCCGCAGGAGGTTCCGGGCGCGCCGCCTGCGCCGTGACCTCATGGCGCTGGTGGTGTTCCTGTTCATCTTTGCGC
TGAACGGCATGCAGGGCCGGCTGGAGGCCGCCGGCGTACCGCAGGCCCTGGGCCCGGTGGAGCCCACGATCCCCGAGCAC
GACCTGATGCTCGCCCAGCGGCGGGCGGAGGCGGCGCGGCGAAGCGCATCCCTGGTCGCCCGGGAAGCGGAGGAGGCGGC
GGCTGATTTGACGGCAGCCCAGCGGCAGCTGGCGCGACAGGCGGATGCCGAGCGGCGTCGGGATCTGGAGCGCATCGCCG
ACCTGGTGCCCCCCGAGTTCCGCCAGATGGTGCTCGATCTTTCCGCCCAGTACGGGGTCGACCCGCGCCTGGTCGCCGCG
GTGGGTCACGTGGAGAGCCGGTGGAACCCGCGAACGGTCGGGACGCATAACGATACAGGACTGATGCAGATCCTGCCCGG
TACCGCGCAGTGGATTGCCAGCCGCCTGGGCTGGACGGAGTACGACCTCTTCGACCCGTGGACCAACTTGCACATGGGCA
TCTGGTACCTGCAGGCGCTTTACCGGGAGTACGGTTCCTGGGACAAGGCCCTGGCCGCGTACAACGGTGGCCCGAGGCAG
GCCCACCTGGGGGCGGATCATCCCTACGTCGGCCGGGTGATGCGCGTCTACGCGGCCCATTAA

Upstream 100 bases:

>100_bases
ATGCTATGAAGCGACTCGTCAATCCTGGCGAACCGCCGGATGCGGACCCGCATGTCCGGTGGTGTGAGAGGACGGGGGCT
AGCCGCCCCCTCCTACTCGA

Downstream 100 bases:

>100_bases
CGAATGGGACATCCATACAGACCATAGAAAAAGTGTCAGGCAGTGGTTCCGCGTTCTCCGGAAACCTGGCAGGAAATACA
CCATACAAAGCGAAACTATA

Product: hypothetical protein

Products: 1,6-Anhydrobond [C]

Alternate protein names: Transglycosylase SLT Domain Protein; Transglycosylase; Soluble Lytic Murein Transglycosylase; Soluble Lytic Transglycosylase; Slt Family Transglycosylase; Lytic Transglycosylase -Like Protein; Lytic Transglycosylase; Lytic Murein Transglycosylase; Murein Transglycosylase Domain-Containing Protein; Transglycosylase SLT Domain-Containing Protein; Secreted Protein; Murein Transglycosylase-Like Protein

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MLRDRLRQISRPAHGKVFLRWEFMRSDRARRRFRARRLRRDLMALVVFLFIFALNGMQGRLEAAGVPQALGPVEPTIPEH
DLMLAQRRAEAARRSASLVAREAEEAAADLTAAQRQLARQADAERRRDLERIADLVPPEFRQMVLDLSAQYGVDPRLVAA
VGHVESRWNPRTVGTHNDTGLMQILPGTAQWIASRLGWTEYDLFDPWTNLHMGIWYLQALYREYGSWDKALAAYNGGPRQ
AHLGADHPYVGRVMRVYAAH

Sequences:

>Translated_260_residues
MLRDRLRQISRPAHGKVFLRWEFMRSDRARRRFRARRLRRDLMALVVFLFIFALNGMQGRLEAAGVPQALGPVEPTIPEH
DLMLAQRRAEAARRSASLVAREAEEAAADLTAAQRQLARQADAERRRDLERIADLVPPEFRQMVLDLSAQYGVDPRLVAA
VGHVESRWNPRTVGTHNDTGLMQILPGTAQWIASRLGWTEYDLFDPWTNLHMGIWYLQALYREYGSWDKALAAYNGGPRQ
AHLGADHPYVGRVMRVYAAH
>Mature_260_residues
MLRDRLRQISRPAHGKVFLRWEFMRSDRARRRFRARRLRRDLMALVVFLFIFALNGMQGRLEAAGVPQALGPVEPTIPEH
DLMLAQRRAEAARRSASLVAREAEEAAADLTAAQRQLARQADAERRRDLERIADLVPPEFRQMVLDLSAQYGVDPRLVAA
VGHVESRWNPRTVGTHNDTGLMQILPGTAQWIASRLGWTEYDLFDPWTNLHMGIWYLQALYREYGSWDKALAAYNGGPRQ
AHLGADHPYVGRVMRVYAAH

Specific function: Murein-Degrading Enzyme. Catalyzes The Cleavage Of The Glycosidic Bonds Between N-Acetylmuramic Acid And N- Acetylglucosamine Residues In Peptidoglycan. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division. [C]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Periplasmic Protein. Tightly Associated With The Murein Sacculus [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 29760; Mature: 29760

Theoretical pI: Translated: 10.73; Mature: 10.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRDRLRQISRPAHGKVFLRWEFMRSDRARRRFRARRLRRDLMALVVFLFIFALNGMQGR
CCHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LEAAGVPQALGPVEPTIPEHDLMLAQRRAEAARRSASLVAREAEEAAADLTAAQRQLARQ
HHHCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADAERRRDLERIADLVPPEFRQMVLDLSAQYGVDPRLVAAVGHVESRWNPRTVGTHNDTG
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
LMQILPGTAQWIASRLGWTEYDLFDPWTNLHMGIWYLQALYREYGSWDKALAAYNGGPRQ
HHEECCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCC
AHLGADHPYVGRVMRVYAAH
CCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MLRDRLRQISRPAHGKVFLRWEFMRSDRARRRFRARRLRRDLMALVVFLFIFALNGMQGR
CCHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LEAAGVPQALGPVEPTIPEHDLMLAQRRAEAARRSASLVAREAEEAAADLTAAQRQLARQ
HHHCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADAERRRDLERIADLVPPEFRQMVLDLSAQYGVDPRLVAAVGHVESRWNPRTVGTHNDTG
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
LMQILPGTAQWIASRLGWTEYDLFDPWTNLHMGIWYLQALYREYGSWDKALAAYNGGPRQ
HHEECCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCC
AHLGADHPYVGRVMRVYAAH
CCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA