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The map label for this gene is ymfH [H]

Identifier: 51894330

GI number: 51894330

Start: 3404754

End: 3406040

Strand: Reverse

Name: ymfH [H]

Synonym: STH3195

Alternate gene names: 51894330

Gene position: 3406040-3404754 (Counterclockwise)

Preceding gene: 51894331

Following gene: 51894329

Centisome position: 95.51

GC content: 68.22

Gene sequence:

>1287_bases
GTGGAGCGGCACTTTGACCCCATCCTGCGTGACGAACTGTACACCGAGCGACTGGAGAACGGCCTGACGGTGGCGGTGCT
GGTCAAGCCCGGCTTCCGGCAGGCCACCGGTCGCGTGGCGGTGCAGTACGGCTCCATCGACAGCTGCTTCGTCGACCCGC
AGTCCGGCGACGAGGTACAGGTGCCTGACGGCATCGCCCATTTCCTGGAACACAAGCTGTTTGAGGGGCCGGACGGCAAC
GTGGCCGACCGGTTCGCGGAGCTGGGCGCGGACGTCAACGCCTACACCACGCACACGCACACGGTGTACTACTTCACCAC
CACCGATCACTTCGCGGCCTGCCTCGACCTGCTGCTGAACTTCGTGCAGGAGCCTTACTTCACGCCCGAGTCGGTGGCCC
GCGAGCAGGGCATCATCGAGCAGGAGATCCGGATGTACCTGGACGACCCGGGCTGGCGCTCCTCCGCCAACCTGATGGAG
GCCCTGTTCGTCCGGCACCCGGTGCGGCTGGACATCGCCGGCACGGTGGAGTCCATCCGCCGGATCGACCAGGACCTGCT
GTACCTCTGCCACCGGATCTTCTATCACCCGTCCAACATGGTGCTGTTCGTCGCCGGCGACCTGGATCCCCGGGCGGTGG
TGGAGCAGGCGAGGGCCGCCTTCGCCGGCCGCCGGTACCCCGCCCAGGCGCCGATCCAGCGGCGCCTGCCCGAGGAGCCG
CAGGCGATCGCCCAGCGGCGGCGGGTCCAGGAGCTGGTCGTGAGCCAGCCGATCTTCCGGCTGGGCTTCAAGGAGAAGCA
GGTCGGCCTTACCGGCCGGCCGCTCCTGGAGCGGGACCTGCTGACTGCCATTCTGCTGGACGTCCTGGTCGGCAAGGGCT
CCCCGCTCTACACCCGGTTGTACGAGAGCGGCCTCATCGACCAGCGCTTCGGCTTCGGGCACGCGCCGGAAGTTACCTTC
GGCTACACCTACGTCTCCGGCCCCACCCCGGATCCCGAGCAGCTGGAGGCCGAGCTCCTGGAGGGGCTGGCGCGGGCCCG
GGAGGAGGGGATCCAGCCGGAGGACTTCGAAAGGGCCCGCCGGAAGCTGGTGGGGCGCATCCTGAACCTGATGAACGACC
TGGAGGGGCTCTCCTACCTGTTCATCGACGGCTTCTTCAAGGGGATCGGGCTCTTCGACGAGATCCCCGCTCTGCAGTCG
CTGACCCTGGATGCGGCGAACCAGCGGCTGCGGGAGCATTTCGACGCCGCGCTGGCGGCCACGTCGGTCATCTCTCCCAG
GCCCTAG

Upstream 100 bases:

>100_bases
CTACCGACAGGTCACCCGGGAGCAGGTGGTCGAGGCCGCCCGCCACTTCACGCCCGACACGGTCTACCTGCTCACCAGGA
AGGAAGGGGGAGCGTAATCG

Downstream 100 bases:

>100_bases
CTGGCTGCCGGGACGATGTCCGGGTAGAGCACAGACGGGGGATCCTCGGCCGCACAGCGTAGTCCCCGGCGTAGACTTTT
AGCGTCCAAAGGTTGGATTT

Product: putative peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MERHFDPILRDELYTERLENGLTVAVLVKPGFRQATGRVAVQYGSIDSCFVDPQSGDEVQVPDGIAHFLEHKLFEGPDGN
VADRFAELGADVNAYTTHTHTVYYFTTTDHFAACLDLLLNFVQEPYFTPESVAREQGIIEQEIRMYLDDPGWRSSANLME
ALFVRHPVRLDIAGTVESIRRIDQDLLYLCHRIFYHPSNMVLFVAGDLDPRAVVEQARAAFAGRRYPAQAPIQRRLPEEP
QAIAQRRRVQELVVSQPIFRLGFKEKQVGLTGRPLLERDLLTAILLDVLVGKGSPLYTRLYESGLIDQRFGFGHAPEVTF
GYTYVSGPTPDPEQLEAELLEGLARAREEGIQPEDFERARRKLVGRILNLMNDLEGLSYLFIDGFFKGIGLFDEIPALQS
LTLDAANQRLREHFDAALAATSVISPRP

Sequences:

>Translated_428_residues
MERHFDPILRDELYTERLENGLTVAVLVKPGFRQATGRVAVQYGSIDSCFVDPQSGDEVQVPDGIAHFLEHKLFEGPDGN
VADRFAELGADVNAYTTHTHTVYYFTTTDHFAACLDLLLNFVQEPYFTPESVAREQGIIEQEIRMYLDDPGWRSSANLME
ALFVRHPVRLDIAGTVESIRRIDQDLLYLCHRIFYHPSNMVLFVAGDLDPRAVVEQARAAFAGRRYPAQAPIQRRLPEEP
QAIAQRRRVQELVVSQPIFRLGFKEKQVGLTGRPLLERDLLTAILLDVLVGKGSPLYTRLYESGLIDQRFGFGHAPEVTF
GYTYVSGPTPDPEQLEAELLEGLARAREEGIQPEDFERARRKLVGRILNLMNDLEGLSYLFIDGFFKGIGLFDEIPALQS
LTLDAANQRLREHFDAALAATSVISPRP
>Mature_428_residues
MERHFDPILRDELYTERLENGLTVAVLVKPGFRQATGRVAVQYGSIDSCFVDPQSGDEVQVPDGIAHFLEHKLFEGPDGN
VADRFAELGADVNAYTTHTHTVYYFTTTDHFAACLDLLLNFVQEPYFTPESVAREQGIIEQEIRMYLDDPGWRSSANLME
ALFVRHPVRLDIAGTVESIRRIDQDLLYLCHRIFYHPSNMVLFVAGDLDPRAVVEQARAAFAGRRYPAQAPIQRRLPEEP
QAIAQRRRVQELVVSQPIFRLGFKEKQVGLTGRPLLERDLLTAILLDVLVGKGSPLYTRLYESGLIDQRFGFGHAPEVTF
GYTYVSGPTPDPEQLEAELLEGLARAREEGIQPEDFERARRKLVGRILNLMNDLEGLSYLFIDGFFKGIGLFDEIPALQS
LTLDAANQRLREHFDAALAATSVISPRP

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Escherichia coli, GI1787770, Length=194, Percent_Identity=26.8041237113402, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71999683, Length=205, Percent_Identity=26.8292682926829, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323421, Length=254, Percent_Identity=27.9527559055118, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323192, Length=379, Percent_Identity=23.7467018469657, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 48272; Mature: 48272

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERHFDPILRDELYTERLENGLTVAVLVKPGFRQATGRVAVQYGSIDSCFVDPQSGDEVQ
CCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHCCCCEEEEECCCCCEEECCCCCCCEE
VPDGIAHFLEHKLFEGPDGNVADRFAELGADVNAYTTHTHTVYYFTTTDHFAACLDLLLN
CCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEEEEEEEEEEECCHHHHHHHHHHHH
FVQEPYFTPESVAREQGIIEQEIRMYLDDPGWRSSANLMEALFVRHPVRLDIAGTVESIR
HHHCCCCCHHHHHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHH
RIDQDLLYLCHRIFYHPSNMVLFVAGDLDPRAVVEQARAAFAGRRYPAQAPIQRRLPEEP
HHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCH
QAIAQRRRVQELVVSQPIFRLGFKEKQVGLTGRPLLERDLLTAILLDVLVGKGSPLYTRL
HHHHHHHHHHHHHHHCHHHHHCCCHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHH
YESGLIDQRFGFGHAPEVTFGYTYVSGPTPDPEQLEAELLEGLARAREEGIQPEDFERAR
HHCCCCHHHCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
RKLVGRILNLMNDLEGLSYLFIDGFFKGIGLFDEIPALQSLTLDAANQRLREHFDAALAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
TSVISPRP
HHHCCCCC
>Mature Secondary Structure
MERHFDPILRDELYTERLENGLTVAVLVKPGFRQATGRVAVQYGSIDSCFVDPQSGDEVQ
CCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHCCCCEEEEECCCCCEEECCCCCCCEE
VPDGIAHFLEHKLFEGPDGNVADRFAELGADVNAYTTHTHTVYYFTTTDHFAACLDLLLN
CCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEEEEEEEEEEECCHHHHHHHHHHHH
FVQEPYFTPESVAREQGIIEQEIRMYLDDPGWRSSANLMEALFVRHPVRLDIAGTVESIR
HHHCCCCCHHHHHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHH
RIDQDLLYLCHRIFYHPSNMVLFVAGDLDPRAVVEQARAAFAGRRYPAQAPIQRRLPEEP
HHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCH
QAIAQRRRVQELVVSQPIFRLGFKEKQVGLTGRPLLERDLLTAILLDVLVGKGSPLYTRL
HHHHHHHHHHHHHHHCHHHHHCCCHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHH
YESGLIDQRFGFGHAPEVTFGYTYVSGPTPDPEQLEAELLEGLARAREEGIQPEDFERAR
HHCCCCHHHCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
RKLVGRILNLMNDLEGLSYLFIDGFFKGIGLFDEIPALQSLTLDAANQRLREHFDAALAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
TSVISPRP
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]