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The map label for this gene is fadR [H]

Identifier: 51894151

GI number: 51894151

Start: 3235068

End: 3235706

Strand: Reverse

Name: fadR [H]

Synonym: STH3015

Alternate gene names: 51894151

Gene position: 3235706-3235068 (Counterclockwise)

Preceding gene: 51894152

Following gene: 51894150

Centisome position: 90.73

GC content: 64.95

Gene sequence:

>639_bases
GTGTCCGTACGGGGCGGCGACAAGTACGCCGCAATCCTGGATGCCGCTCAGCACGTGATCGCCCGACAGGGCTACCACAA
CGCCCAGATCTCGCGCATCGCCGCGGAGGCCGGCGTCGCAGCGGGAACCGTCTACCTCTACTTCCAGAACAAGCCGGACC
TGCTCGTCTGCCTCTTCCGGGAGCGGCTGAATCTGCTGGTCAGCGAGATCAAGGAAGCCATCGGGGACGCGGTCGATCCC
CGCGAGAAGCTCAGGCGGGCCATCGCGCAGCACCTGCGGTCCCTGGGCACCCGCCCGGAGCTGGCCGCCGTCACCCAGAT
CGAGATGCGCCAGGCGGACACGCAGGTGCAGCAGCAGATCAGCAACCTGATGAAGGGCTGGTTCGCGGTCATCGACCAGA
TCATCGCTGAGGGGCAGGCGTCAGGGCTCTTCACCCGTGAGGTCCCGGCCAAGCAGATCCGCAACCTGATCTTCGGCACC
CTCGACCAGACCGTGACCGCATGGGTGATGTCGGGGTACAAGTTCGACATCCTGGCCCTGGCTGAGCCCACCTATCGGCT
CATCGCCCATGGCGTGATGCAACACCGCGAAGGAGGCGTGGGGAATGGAGATTCTGGTTCTCCTGAAGCAGACCTTTGA

Upstream 100 bases:

>100_bases
GCATCATCGAGTTCCGGGACGAGCTGCCCAAGTCCCTGGTCGGCAAGGTGCTGCGGCGGGTGCTCCTCGAGGAGGAACAG
AGCCGGAAGGGGGTCGTGTA

Downstream 100 bases:

>100_bases
CACAGAAGCAAAGGTAACCGTGAAGGATGGCCGCGTGGTCGACGACGACGTTACGCTGGTGATCAACCCCTACGATGAGT
ACGCCGTGGAGGAAGCCCTG

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MSVRGGDKYAAILDAAQHVIARQGYHNAQISRIAAEAGVAAGTVYLYFQNKPDLLVCLFRERLNLLVSEIKEAIGDAVDP
REKLRRAIAQHLRSLGTRPELAAVTQIEMRQADTQVQQQISNLMKGWFAVIDQIIAEGQASGLFTREVPAKQIRNLIFGT
LDQTVTAWVMSGYKFDILALAEPTYRLIAHGVMQHREGGVGNGDSGSPEADL

Sequences:

>Translated_212_residues
MSVRGGDKYAAILDAAQHVIARQGYHNAQISRIAAEAGVAAGTVYLYFQNKPDLLVCLFRERLNLLVSEIKEAIGDAVDP
REKLRRAIAQHLRSLGTRPELAAVTQIEMRQADTQVQQQISNLMKGWFAVIDQIIAEGQASGLFTREVPAKQIRNLIFGT
LDQTVTAWVMSGYKFDILALAEPTYRLIAHGVMQHREGGVGNGDSGSPEADL
>Mature_211_residues
SVRGGDKYAAILDAAQHVIARQGYHNAQISRIAAEAGVAAGTVYLYFQNKPDLLVCLFRERLNLLVSEIKEAIGDAVDPR
EKLRRAIAQHLRSLGTRPELAAVTQIEMRQADTQVQQQISNLMKGWFAVIDQIIAEGQASGLFTREVPAKQIRNLIFGTL
DQTVTAWVMSGYKFDILALAEPTYRLIAHGVMQHREGGVGNGDSGSPEADL

Specific function: Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation, including acdA, fadA, fadB, fadE, fadF, fadG, fadH, fadM, fadN, lcfA and lcfB. Binding of FadR to DNA is specifical

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647
- InterPro:   IPR013570 [H]

Pfam domain/function: PF08359 TetR_C_4; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 23271; Mature: 23140

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVRGGDKYAAILDAAQHVIARQGYHNAQISRIAAEAGVAAGTVYLYFQNKPDLLVCLFR
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHH
ERLNLLVSEIKEAIGDAVDPREKLRRAIAQHLRSLGTRPELAAVTQIEMRQADTQVQQQI
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
SNLMKGWFAVIDQIIAEGQASGLFTREVPAKQIRNLIFGTLDQTVTAWVMSGYKFDILAL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
AEPTYRLIAHGVMQHREGGVGNGDSGSPEADL
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SVRGGDKYAAILDAAQHVIARQGYHNAQISRIAAEAGVAAGTVYLYFQNKPDLLVCLFR
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHH
ERLNLLVSEIKEAIGDAVDPREKLRRAIAQHLRSLGTRPELAAVTQIEMRQADTQVQQQI
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
SNLMKGWFAVIDQIIAEGQASGLFTREVPAKQIRNLIFGTLDQTVTAWVMSGYKFDILAL
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
AEPTYRLIAHGVMQHREGGVGNGDSGSPEADL
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]