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The map label for this gene is prsA [H]

Identifier: 51894079

GI number: 51894079

Start: 3168074

End: 3168967

Strand: Reverse

Name: prsA [H]

Synonym: STH2943

Alternate gene names: 51894079

Gene position: 3168967-3168074 (Counterclockwise)

Preceding gene: 51894080

Following gene: 51894078

Centisome position: 88.86

GC content: 66.11

Gene sequence:

>894_bases
GTGTTGGCCAACGGGAATAACCGGGCGACGATCGCCCTGGCCGTGGTGGCCACCCTGGTGGTGGCAGGACTCGGCGGCTA
CTTCGTGGGCAGCAGCCTGCAGCGGCCCGGCACCGGCAACGATCCCGCCGTGGTCGCGACGGTCAACGGCGAGCAGATCA
CCCGGGACGAAGTGCACCAGAAGCTGATGACCTACTACGGGGCAGCCGTCGTCGACGACATGATTCTCACCCGCCTCGTG
GATCAGGAAGCCGCCAGGGCGGGCGTGACCGTGACCGATGCCGAGGTGGAGGAGGAGGTCGAGGCGACCAAGGCCGCGTA
CGGCGGCGACCTGTACTTCTCCTGGGCGCTGAGCCAGTATGGGCTGAGCGAGGCGCAGTTCCGCGACATGCTGCGCCGGG
ACATGGTCGCCACCGCTGTGCTCCGCCAGCAGCTGCAGCCGGACGATGCCACGCTGAAGGCGTACTTCGACGAGATGCAG
AGCGCGGAACAGACTCGGAAGATCAAGGTGCGCCACATCCTCGTCGACACGGAGGAGAAGGCCAACGAGATTAAGGCCCG
GCTGGACGCCGGCGCCGACTTCGCCCAGCTCGCGCAGGCGGAGTCCAAGGACACGGCCAGCGCCGCCAAGGGCGGCGACC
TGGGTCTGATCGGCAAGGGCGACACCGTCTCCGAGTTTGAGGCAGCAGCCTTCGCCCTGAACGACGGTGAGATCTCCGCC
CCCGTGCAGAGCACGTACGGCTGGCACATCATCCAGGCCTACCAGTTGCACTTTGAGCAGGAGAAGCAGACCATTCTGGA
GCAGTATCTGAACGAGAAGGTGAGCGCGCGGCTGGGCACCTGGTACAGCGAACTGCGGGAGAACGCCCAGATCACGAACA
CGCTCGCCCAGTAA

Upstream 100 bases:

>100_bases
AGCGGATACGCGCCCGCGTTCCCGCCATTGGCATCCGGCCCGAAGTGCGTTACCATAGCGGGTGTGACCCTGATTCAAGC
CTGAACCAAAGGAGCGTGGC

Downstream 100 bases:

>100_bases
GCGCCTGAGACCGGGCCAGGCCAGGGGGCAACCTCCTGGCCTGCTGGTGCATGAACGGGGGTGGTGTCGGGTGGACCCGC
GCGCGCGCTGGCGGCTCTTC

Product: putative post-translocation molecular chaperone

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MLANGNNRATIALAVVATLVVAGLGGYFVGSSLQRPGTGNDPAVVATVNGEQITRDEVHQKLMTYYGAAVVDDMILTRLV
DQEAARAGVTVTDAEVEEEVEATKAAYGGDLYFSWALSQYGLSEAQFRDMLRRDMVATAVLRQQLQPDDATLKAYFDEMQ
SAEQTRKIKVRHILVDTEEKANEIKARLDAGADFAQLAQAESKDTASAAKGGDLGLIGKGDTVSEFEAAAFALNDGEISA
PVQSTYGWHIIQAYQLHFEQEKQTILEQYLNEKVSARLGTWYSELRENAQITNTLAQ

Sequences:

>Translated_297_residues
MLANGNNRATIALAVVATLVVAGLGGYFVGSSLQRPGTGNDPAVVATVNGEQITRDEVHQKLMTYYGAAVVDDMILTRLV
DQEAARAGVTVTDAEVEEEVEATKAAYGGDLYFSWALSQYGLSEAQFRDMLRRDMVATAVLRQQLQPDDATLKAYFDEMQ
SAEQTRKIKVRHILVDTEEKANEIKARLDAGADFAQLAQAESKDTASAAKGGDLGLIGKGDTVSEFEAAAFALNDGEISA
PVQSTYGWHIIQAYQLHFEQEKQTILEQYLNEKVSARLGTWYSELRENAQITNTLAQ
>Mature_297_residues
MLANGNNRATIALAVVATLVVAGLGGYFVGSSLQRPGTGNDPAVVATVNGEQITRDEVHQKLMTYYGAAVVDDMILTRLV
DQEAARAGVTVTDAEVEEEVEATKAAYGGDLYFSWALSQYGLSEAQFRDMLRRDMVATAVLRQQLQPDDATLKAYFDEMQ
SAEQTRKIKVRHILVDTEEKANEIKARLDAGADFAQLAQAESKDTASAAKGGDLGLIGKGDTVSEFEAAAFALNDGEISA
PVQSTYGWHIIQAYQLHFEQEKQTILEQYLNEKVSARLGTWYSELRENAQITNTLAQ

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

None

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF05698 Trigger_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 32375; Mature: 32375

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLANGNNRATIALAVVATLVVAGLGGYFVGSSLQRPGTGNDPAVVATVNGEQITRDEVHQ
CCCCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHH
KLMTYYGAAVVDDMILTRLVDQEAARAGVTVTDAEVEEEVEATKAAYGGDLYFSWALSQY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHCCCCCEEEHHHHHH
GLSEAQFRDMLRRDMVATAVLRQQLQPDDATLKAYFDEMQSAEQTRKIKVRHILVDTEEK
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEEEEEECCHHH
ANEIKARLDAGADFAQLAQAESKDTASAAKGGDLGLIGKGDTVSEFEAAAFALNDGEISA
HHHHHHHHCCCCCHHHHHHHCCCCHHHHCCCCCEEEECCCCCHHHHHHHHEEECCCCCCC
PVQSTYGWHIIQAYQLHFEQEKQTILEQYLNEKVSARLGTWYSELRENAQITNTLAQ
CHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCC
>Mature Secondary Structure
MLANGNNRATIALAVVATLVVAGLGGYFVGSSLQRPGTGNDPAVVATVNGEQITRDEVHQ
CCCCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHH
KLMTYYGAAVVDDMILTRLVDQEAARAGVTVTDAEVEEEVEATKAAYGGDLYFSWALSQY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHCCCCCEEEHHHHHH
GLSEAQFRDMLRRDMVATAVLRQQLQPDDATLKAYFDEMQSAEQTRKIKVRHILVDTEEK
CCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEEEEEEECCHHH
ANEIKARLDAGADFAQLAQAESKDTASAAKGGDLGLIGKGDTVSEFEAAAFALNDGEISA
HHHHHHHHCCCCCHHHHHHHCCCCHHHHCCCCCEEEECCCCCHHHHHHHHEEECCCCCCC
PVQSTYGWHIIQAYQLHFEQEKQTILEQYLNEKVSARLGTWYSELRENAQITNTLAQ
CHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA